LLPS-Drm-0487
Arl2

▼ OVERVIEW

Status: Unreviewed
Protein Name: ADP-ribosylation factor-like protein 2
Gene Name: Arl2, Arf84F, CG7435
Ensembl Gene: FBgn0004908
Ensembl Protein: FBpp0081328
Organism: Drosophila melanogaster
Taxa ID: 7227
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGFLTVLKKM  RQKEREMRIL  LLGLDNAGKT  TILKRFNGEP  IDTISPTLGF  NIKTLEHNGY  60
61    TLNMWDVGGQ  KSLRSYWRNY  FESTDGLVWV  VDSADRMRLE  SCGQELQVLL  QEERLAGATL  120
121   LVLCNKQDLP  GALSSNEIKE  ILHLEDITTH  HWLVAGVSAV  TGEKLLSSMD  WLIADIAKRI  180
181   FTLD  184
Nucleotide CDS Sequence (FASTA)
1     ATGGGCTTCC  TCACAGTATT  AAAAAAGATG  CGACAGAAGG  AAAGGGAAAT  GCGCATATTA  60
61    CTGCTAGGTC  TGGATAATGC  CGGCAAGACG  ACAATCCTGA  AGCGCTTTAA  TGGCGAACCC  120
121   ATAGACACCA  TCTCACCCAC  ACTGGGATTC  AATATTAAAA  CCTTGGAGCA  CAACGGCTAC  180
181   ACCCTGAATA  TGTGGGATGT  CGGTGGCCAG  AAGTCTCTGC  GATCCTACTG  GAGAAACTAC  240
241   TTCGAGTCCA  CTGATGGTCT  GGTCTGGGTG  GTGGATAGCG  CTGACAGGAT  GCGCCTAGAG  300
301   TCCTGCGGCC  AGGAGCTGCA  AGTTCTGCTC  CAGGAAGAGC  GATTAGCTGG  AGCCACACTC  360
361   CTAGTTCTCT  GCAACAAACA  GGATCTACCG  GGAGCCCTCT  CATCCAACGA  AATTAAAGAG  420
421   ATACTACACC  TAGAGGATAT  CACCACACAT  CATTGGCTGG  TGGCCGGAGT  TAGTGCAGTG  480
481   ACTGGCGAGA  AACTGCTTAG  CTCCATGGAC  TGGTTGATCG  CCGATATAGC  TAAGCGTATA  540
541   TTCACTTTGG  AT  552

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Lipoprotein
Myristate
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Presynapse
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Establishment of mitotic spindle orientation
Biological Process
Establishment or maintenance of neuroblast polarity
Biological Process
Microtubule cytoskeleton organization involved in mitosis
Biological Process
Neurotransmitter secretion
Biological Process
Synaptic vesicle endocytosis

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caf-0071Canis familiaris83.338e-59 187
LLPS-Man-2179Macaca nemestrina82.355e-57 185
LLPS-Pof-2421Poecilia formosa78.027e-95 280
LLPS-Tar-3071Takifugu rubripes77.479e-96 283
LLPS-Ten-2235Tetraodon nigroviridis76.923e-94 279
LLPS-Xet-3228Xenopus tropicalis76.631e-95 282
LLPS-Orn-2483Oreochromis niloticus76.633e-95 281
LLPS-Dar-0132Danio rerio76.632e-95 282
LLPS-Xim-2435Xiphophorus maculatus76.373e-95 281
LLPS-Eqc-2538Equus caballus76.097e-96 283
LLPS-Icp-3120Ictalurus punctatus76.091e-94 280
LLPS-Leo-1378Lepisosteus oculatus76.091e-92 275
LLPS-Nol-4552Nomascus leucogenys75.543e-93 276
LLPS-Otg-4746Otolemur garnettii75.544e-95 281
LLPS-Pap-4067Pan paniscus75.544e-95 281
LLPS-Pat-2385Pan troglodytes75.544e-95 281
LLPS-Hos-1559Homo sapiens75.549e-96 283
LLPS-Scm-3572Scophthalmus maximus75.541e-94 280
LLPS-Mup-3803Mustela putorius furo75.543e-94 279
LLPS-Gaa-3565Gasterosteus aculeatus75.545e-94 278
LLPS-Asm-2292Astyanax mexicanus75.541e-93 277
LLPS-Fud-0699Fukomys damarensis75.548e-95 280
LLPS-Gog-4750Gorilla gorilla75.544e-95 281
LLPS-Orl-3596Oryzias latipes75.545e-92 273
LLPS-Mod-3204Monodelphis domestica75.277e-94 278
LLPS-Caj-4011Callithrix jacchus75.271e-93 278
LLPS-Sah-0656Sarcophilus harrisii75.276e-94 278
LLPS-Ict-4014Ictidomys tridecemlineatus75.08e-95 280
LLPS-Mam-1134Macaca mulatta75.04e-94 278
LLPS-Cap-2524Cavia porcellus75.08e-94 278
LLPS-Loa-2863Loxodonta africana75.04e-93 276
LLPS-Fec-4136Felis catus75.08e-94 278
LLPS-Paa-3136Papio anubis75.01e-93 278
LLPS-Ova-2560Ovis aries75.04e-94 279
LLPS-Myl-1566Myotis lucifugus75.02e-94 280
LLPS-Bot-1797Bos taurus75.04e-94 279
LLPS-Cea-2669Cercocebus atys75.04e-94 278
LLPS-Maf-4465Macaca fascicularis75.04e-94 278
LLPS-Cii-0249Ciona intestinalis75.04e-91 271
LLPS-Chs-3184Chlorocebus sabaeus75.04e-94 278
LLPS-Aon-3471Aotus nancymaae74.738e-91 270
LLPS-Rhb-0692Rhinopithecus bieti74.467e-93 276
LLPS-Pes-3527Pelodiscus sinensis74.466e-92 274
LLPS-Dio-4365Dipodomys ordii74.467e-93 275
LLPS-Sus-3071Sus scrofa74.469e-93 276
LLPS-Mea-0664Mesocricetus auratus74.461e-93 278
LLPS-Mum-4962Mus musculus73.911e-93 277
LLPS-Ran-3257Rattus norvegicus73.713e-88 263
LLPS-Aim-1390Ailuropoda melanoleuca73.168e-92 273
LLPS-Anc-0940Anolis carolinensis72.964e-76 232
LLPS-Urm-2894Ursus maritimus70.271e-82 249
LLPS-Cis-1955Ciona savignyi70.112e-87 261
LLPS-Orc-2839Oryctolagus cuniculus69.025e-87 261
LLPS-Lep-2225Leersia perrieri64.081e-57 187
LLPS-Coo-1050Colletotrichum orbiculare63.311e-55 179
LLPS-Sem-1782Selaginella moellendorffii62.72e-74 228
LLPS-Orgl-1570Oryza glumaepatula62.684e-58 186
LLPS-Coc-1505Corchorus capsularis62.583e-63 202
LLPS-Scf-4057Scleropages formosus61.414e-70 216
LLPS-Cae-0765Caenorhabditis elegans61.412e-76 233
LLPS-Bro-2164Brassica oleracea61.087e-68 212
LLPS-Mae-0707Manihot esculenta61.085e-74 228
LLPS-Brn-3034Brassica napus61.087e-68 212
LLPS-Asf-0185Aspergillus flavus60.566e-52 171
LLPS-Arl-2017Arabidopsis lyrata60.542e-61 195
LLPS-Gor-1003Gossypium raimondii60.03e-74 228
LLPS-Brr-0483Brassica rapa60.07e-66 207
LLPS-Hov-2068Hordeum vulgare60.01e-72 226
LLPS-Chr-1730Chlamydomonas reinhardtii60.01e-61 195
LLPS-Ori-0569Oryza indica60.04e-71 220
LLPS-Tra-2776Triticum aestivum59.462e-73 226
LLPS-Prp-2578Prunus persica59.382e-56 183
LLPS-Org-2251Oryza glaberrima58.924e-72 223
LLPS-Cas-2287Carlito syrichta58.769e-60 190
LLPS-Ved-0922Verticillium dahliae58.333e-50 165
LLPS-Trv-1403Trichoderma virens58.12e-66 208
LLPS-Tru-1353Triticum urartu57.811e-70 219
LLPS-Lac-3860Latimeria chalumnae57.815e-65 205
LLPS-Trr-0348Trichoderma reesei57.545e-66 207
LLPS-Orm-1093Oryza meridionalis56.761e-64 204
LLPS-Cogr-0464Colletotrichum graminicola56.114e-62 197
LLPS-Ora-3144Ornithorhynchus anatinus55.146e-67 209
LLPS-Ere-0764Erinaceus europaeus51.832e-46 156
LLPS-Put-0380Puccinia triticina51.523e-54 180
LLPS-Scc-1520Schizosaccharomyces cryophilus51.141e-57 185
LLPS-Gaga-0460Gallus gallus50.283e-53 174
LLPS-Anp-1554Anas platyrhynchos50.02e-52 172
LLPS-Meg-1283Meleagris gallopavo50.02e-52 172
LLPS-Php-2145Physcomitrella patens50.01e-50 168
LLPS-Poa-0243Pongo abelii49.725e-51 169
LLPS-Nia-2605Nicotiana attenuata49.695e-44 150
LLPS-Cus-0288Cucumis sativus49.691e-43 149
LLPS-Dac-0065Daucus carota49.691e-43 150
LLPS-Fia-1981Ficedula albicollis49.446e-54 176
LLPS-Tag-2242Taeniopygia guttata49.164e-53 174
LLPS-Tut-2356Tursiops truncatus49.151e-47 160
LLPS-Phv-1926Phaseolus vulgaris49.061e-43 149
LLPS-Met-0249Medicago truncatula49.062e-43 149
LLPS-Thc-2325Theobroma cacao49.067e-44 150
LLPS-Glm-2110Glycine max48.732e-43 149
LLPS-Gas-1069Galdieria sulphuraria48.354e-50 166
LLPS-Osl-0949Ostreococcus lucimarinus47.82e-41 144
LLPS-Orbr-1283Oryza brachyantha46.712e-42 148
LLPS-Orp-0909Oryza punctata46.711e-41 147
LLPS-Pot-1932Populus trichocarpa46.711e-42 147
LLPS-Hea-0819Helianthus annuus46.711e-42 148
LLPS-Mua-1165Musa acuminata46.434e-43 150
LLPS-Zem-2064Zea mays46.395e-43 149
LLPS-Orr-2145Oryza rufipogon46.391e-43 149
LLPS-Ors-2090Oryza sativa46.391e-43 149
LLPS-Orb-1040Oryza barthii46.391e-43 149
LLPS-Brd-1923Brachypodium distachyon46.116e-44 150
LLPS-Kop-1194Komagataella pastoris46.071e-41 145
LLPS-Yal-0856Yarrowia lipolytica46.031e-48 163
LLPS-Amt-1093Amborella trichopoda45.787e-43 147
LLPS-Viv-2049Vitis vinifera45.789e-43 147
LLPS-Art-0760Arabidopsis thaliana45.781e-42 147
LLPS-Vir-1926Vigna radiata45.789e-43 147
LLPS-Sot-2247Solanum tuberosum45.781e-42 147
LLPS-Via-2415Vigna angularis45.781e-42 147
LLPS-Orni-1877Oryza nivara45.786e-43 148
LLPS-Sol-0593Solanum lycopersicum45.789e-43 147
LLPS-Asni-1329Aspergillus niger45.731e-40 142
LLPS-Asn-0113Aspergillus nidulans45.661e-40 142
LLPS-Mal-4556Mandrillus leucophaeus45.282e-40 141
LLPS-Sac-1470Saccharomyces cerevisiae45.26e-44 150
LLPS-Asg-1474Ashbya gossypii44.442e-41 144
LLPS-Crn-1263Cryptococcus neoformans44.312e-40 141
LLPS-Pug-1314Puccinia graminis44.247e-41 142
LLPS-Tum-0971Tuber melanosporum44.09e-43 147
LLPS-Spr-0382Sporisorium reilianum43.371e-40 142
LLPS-Usm-1520Ustilago maydis43.371e-40 142