DrLLPS - Data resource of LLPS

LLPS-Dio-3372
Pgls

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	6-phosphogluconolactonase
Gene Name:	Pgls
Ensembl Gene:	ENSDORG00000007681.2
Ensembl Protein:	ENSDORP00000007197.2
Organism:	Dipodomys ordii
Taxa ID:	10020
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0118	O95336	Client	Nucleolus	84.57	1e-93	280

▼ FUNCTION

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSDORT00000007680.2	ENSDORP00000007197.2
UniProt		A0A1S3G4P7, A0A1S3G4P7_DIPOR
RefSeq	, XM_013028339.1	, XP_012883793.1, XP_012883793.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 THLLSRLPVP ASQVLSIDPA LPLEAAAEDY ATKLRQALGD DAIPVFDLLI LGVGPDGHTC 60 61 SLFPGHPLLQ ERDRIVAPIS DSPKPPPQRV TLTLPVLNAA RTVVFVATGE GKAAVLKRIL 120 121 EETEESPLPA ALVRPHTGQL RWFLDESAAR LLTVPFEKHS AL 162
Nucleotide CDS Sequence (FASTA)
1 ACGCACCTGC TCTCCAGACT GCCCGTCCCC GCCAGCCAGG TGCTCAGCAT CGACCCCGCG 60 61 CTGCCGCTAG AGGCGGCGGC CGAGGACTAC GCGACCAAGC TCAGACAGGC CCTGGGAGAT 120 121 GACGCCATTC CAGTGTTTGA CCTGCTGATC CTGGGCGTGG GCCCCGATGG CCACACCTGC 180 181 TCCCTCTTCC CCGGACACCC CCTCCTGCAA GAGCGAGACA GGATTGTGGC CCCCATCAGT 240 241 GACTCCCCGA AGCCGCCGCC CCAGCGCGTG ACCCTCACCC TGCCTGTGCT CAATGCCGCA 300 301 CGGACCGTCG TCTTTGTGGC CACTGGGGAA GGCAAGGCTG CCGTCCTGAA GCGCATCCTG 360 361 GAGGAGACAG AGGAAAGCCC GCTCCCGGCC GCGCTGGTGC GGCCGCACAC GGGGCAGCTC 420 421 CGCTGGTTCC TGGACGAGTC GGCCGCACGC CTGCTGACGG TGCCCTTCGA GAAGCATTCC 480 481 GCTTTGTAG 489

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0378	Hydrolase
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0017057	Molecular Function	6-phosphogluconolactonase activity
GO:0005975	Biological Process	Carbohydrate metabolic process
GO:0006098	Biological Process	Pentose-phosphate shunt

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Fud-1879	Fukomys damarensis	85.8	3e-95	280
LLPS-Hos-0118	Homo sapiens	84.57	3e-94	281
LLPS-Pap-4251	Pan paniscus	84.57	4e-94	280
LLPS-Pat-3122	Pan troglodytes	84.57	4e-94	280
LLPS-Caf-0830	Canis familiaris	84.57	6e-94	280
LLPS-Poa-3663	Pongo abelii	84.47	8e-93	278
LLPS-Rhb-4128	Rhinopithecus bieti	83.95	7e-94	278
LLPS-Fec-3689	Felis catus	83.95	7e-93	277
LLPS-Nol-2353	Nomascus leucogenys	83.95	7e-94	280
LLPS-Ict-0191	Ictidomys tridecemlineatus	83.95	2e-93	279
LLPS-Eqc-1734	Equus caballus	83.95	2e-93	278
LLPS-Myl-4251	Myotis lucifugus	83.95	1e-92	276
LLPS-Mup-2796	Mustela putorius furo	83.95	7e-93	277
LLPS-Urm-4056	Ursus maritimus	83.33	2e-93	276
LLPS-Man-2920	Macaca nemestrina	83.33	2e-93	278
LLPS-Cas-3782	Carlito syrichta	83.33	2e-91	272
LLPS-Mam-2996	Macaca mulatta	83.33	2e-93	278
LLPS-Chs-3956	Chlorocebus sabaeus	83.33	3e-92	278
LLPS-Maf-0157	Macaca fascicularis	83.33	2e-93	278
LLPS-Cea-4008	Cercocebus atys	83.33	5e-93	278
LLPS-Mal-3737	Mandrillus leucophaeus	83.33	5e-93	276
LLPS-Paa-2688	Papio anubis	83.33	7e-93	277
LLPS-Otg-3715	Otolemur garnettii	82.72	8e-92	275
LLPS-Cap-3317	Cavia porcellus	82.72	1e-90	271
LLPS-Caj-2052	Callithrix jacchus	82.72	4e-91	273
LLPS-Ova-2134	Ovis aries	82.72	3e-91	273
LLPS-Tut-0386	Tursiops truncatus	82.72	2e-92	276
LLPS-Sus-0131	Sus scrofa	82.1	2e-91	274
LLPS-Bot-2966	Bos taurus	82.1	1e-90	271
LLPS-Loa-4536	Loxodonta africana	81.99	3e-90	271
LLPS-Mum-3124	Mus musculus	81.48	1e-87	264
LLPS-Ran-4065	Rattus norvegicus	81.48	2e-88	267
LLPS-Meg-2584	Meleagris gallopavo	80.43	4e-45	149
LLPS-Pes-3031	Pelodiscus sinensis	79.57	5e-46	152
LLPS-Mod-3490	Monodelphis domestica	79.01	1e-87	264
LLPS-Ora-3530	Ornithorhynchus anatinus	78.4	7e-87	261
LLPS-Mea-3697	Mesocricetus auratus	77.16	2e-84	256
LLPS-Gaga-2304	Gallus gallus	76.4	3e-80	245
LLPS-Gog-3378	Gorilla gorilla	73.68	3e-10	59.3
LLPS-Xet-3700	Xenopus tropicalis	73.51	3e-71	219
LLPS-Anc-3964	Anolis carolinensis	72.39	8e-78	238
LLPS-Lac-3277	Latimeria chalumnae	70.19	2e-74	230
LLPS-Leo-3623	Lepisosteus oculatus	63.98	5e-65	206
LLPS-Aon-0822	Aotus nancymaae	62.05	9e-55	179
LLPS-Dar-3634	Danio rerio	62.03	6e-64	203
LLPS-Scf-2478	Scleropages formosus	61.49	2e-62	199
LLPS-Cii-0018	Ciona intestinalis	61.11	1e-14	72.4
LLPS-Icp-2305	Ictalurus punctatus	60.76	6e-61	195
LLPS-Chc-0635	Chondrus crispus	60.71	7e-47	158
LLPS-Asm-0701	Astyanax mexicanus	60.13	2e-62	199
LLPS-Orl-2963	Oryzias latipes	58.86	4e-59	191
LLPS-Scm-0255	Scophthalmus maximus	58.39	1e-58	191
LLPS-Pof-2873	Poecilia formosa	58.39	4e-61	196
LLPS-Xim-2088	Xiphophorus maculatus	58.39	4e-61	196
LLPS-Orn-1096	Oreochromis niloticus	58.23	5e-61	196
LLPS-Trr-1252	Trichoderma reesei	57.89	1e-36	132
LLPS-Trv-1446	Trichoderma virens	57.89	1e-35	130
LLPS-Tar-2213	Takifugu rubripes	57.76	1e-59	192
LLPS-Ten-2163	Tetraodon nigroviridis	57.5	4e-58	188
LLPS-Ved-1484	Verticillium dahliae	57.02	2e-35	130
LLPS-Fuo-1033	Fusarium oxysporum	57.02	3e-36	132
LLPS-Fuv-1156	Fusarium verticillioides	57.02	2e-36	132
LLPS-Nec-1058	Neurospora crassa	57.02	2e-36	132
LLPS-Cog-0796	Colletotrichum gloeosporioides	56.14	2e-35	130
LLPS-Cogr-1013	Colletotrichum graminicola	56.14	5e-36	131
LLPS-Asn-0079	Aspergillus nidulans	56.14	7e-37	134
LLPS-Map-0700	Magnaporthe poae	56.14	9e-35	126
LLPS-Cis-1818	Ciona savignyi	56.12	3e-46	157
LLPS-Gaa-1549	Gasterosteus aculeatus	55.9	2e-56	184
LLPS-Coo-0692	Colletotrichum orbiculare	55.26	1e-34	128
LLPS-Asni-1548	Aspergillus niger	55.26	7e-37	134
LLPS-Nef-1251	Neosartorya fischeri	54.39	1e-35	130
LLPS-Beb-1638	Beauveria bassiana	54.39	2e-33	124
LLPS-Asfu-0014	Aspergillus fumigatus	54.39	1e-35	130
LLPS-Scs-0848	Sclerotinia sclerotiorum	54.39	1e-33	125
LLPS-Zyt-1068	Zymoseptoria tritici	54.39	1e-33	125
LLPS-Osl-0836	Ostreococcus lucimarinus	54.2	4e-39	139
LLPS-Crn-0351	Cryptococcus neoformans	53.38	2e-38	139
LLPS-Php-1834	Physcomitrella patens	52.87	3e-47	162
LLPS-Phn-0870	Phaeosphaeria nodorum	51.26	1e-33	125
LLPS-Yal-1359	Yarrowia lipolytica	51.06	4e-39	139
LLPS-Sem-1874	Selaginella moellendorffii	50.97	7e-40	141
LLPS-Abg-0897	Absidia glauca	50.32	2e-46	158
LLPS-Usm-0224	Ustilago maydis	49.68	1e-37	135
LLPS-Ast-1121	Aspergillus terreus	49.24	4e-32	124
LLPS-Gag-1509	Gaeumannomyces graminis	49.07	1e-36	132
LLPS-Spr-0868	Sporisorium reilianum	49.03	3e-37	134
LLPS-Kop-0747	Komagataella pastoris	48.7	5e-32	120
LLPS-Lem-0905	Leptosphaeria maculans	48.18	4e-27	108
LLPS-Sac-1430	Saccharomyces cerevisiae	48.15	7e-24	99.0
LLPS-Pug-1447	Puccinia graminis	47.74	2e-36	132
LLPS-Mao-0001	Magnaporthe oryzae	47.5	8e-36	130
LLPS-Scc-1340	Schizosaccharomyces cryophilus	47.33	6e-35	128
LLPS-Chr-1294	Chlamydomonas reinhardtii	47.2	3e-37	137
LLPS-Met-0733	Medicago truncatula	47.17	1e-42	149
LLPS-Mel-1201	Melampsora laricipopulina	47.06	2e-36	132
LLPS-Drm-0776	Drosophila melanogaster	47.02	2e-37	134
LLPS-Fus-1008	Fusarium solani	46.88	2e-37	135
LLPS-Pot-2280	Populus trichocarpa	46.88	8e-39	139
LLPS-Scp-1423	Schizosaccharomyces pombe	46.72	1e-32	122
LLPS-Asc-1657	Aspergillus clavatus	46.71	4e-34	126
LLPS-Scj-1446	Schizosaccharomyces japonicus	46.67	3e-33	124
LLPS-Asf-1143	Aspergillus flavus	46.63	7e-38	136
LLPS-Aso-1548	Aspergillus oryzae	46.63	8e-38	136
LLPS-Pytr-0408	Pyrenophora triticirepentis	46.36	6e-26	104
LLPS-Pyt-1619	Pyrenophora teres	46.36	6e-26	104
LLPS-Dos-1118	Dothistroma septosporum	46.3	1e-34	127
LLPS-Mae-0738	Manihot esculenta	46.25	6e-39	139
LLPS-Miv-1578	Microbotryum violaceum	46.06	2e-36	132
LLPS-Tum-1346	Tuber melanosporum	46.06	3e-34	127
LLPS-Nia-1438	Nicotiana attenuata	45.62	4e-38	137
LLPS-Prp-0238	Prunus persica	45.62	5e-38	137
LLPS-Sol-0919	Solanum lycopersicum	45.62	7e-38	136
LLPS-Sot-2153	Solanum tuberosum	45.62	9e-38	136
LLPS-Hea-0827	Helianthus annuus	45.34	1e-38	138
LLPS-Phv-1622	Phaseolus vulgaris	45.0	3e-36	132
LLPS-Gor-2327	Gossypium raimondii	45.0	2e-37	135
LLPS-Coc-1514	Corchorus capsularis	45.0	3e-37	134
LLPS-Thc-1735	Theobroma cacao	45.0	1e-36	133
LLPS-Vir-1788	Vigna radiata	45.0	2e-36	132
LLPS-Via-1946	Vigna angularis	45.0	2e-36	132
LLPS-Arl-2890	Arabidopsis lyrata	44.79	1e-35	130
LLPS-Dac-2368	Daucus carota	44.72	7e-40	141
LLPS-Sei-2072	Setaria italica	44.72	1e-42	150
LLPS-Amt-1288	Amborella trichopoda	44.65	3e-40	142
LLPS-Brn-1563	Brassica napus	44.44	5e-35	129
LLPS-Cus-2169	Cucumis sativus	44.44	5e-38	137
LLPS-Glm-2996	Glycine max	44.38	2e-35	130
LLPS-Viv-1966	Vitis vinifera	43.95	2e-35	129
LLPS-Put-0558	Puccinia triticina	43.37	4e-33	123
LLPS-Mua-2524	Musa acuminata	43.29	5e-38	137
LLPS-Cae-1557	Caenorhabditis elegans	43.07	3e-24	100
LLPS-Blg-0033	Blumeria graminis	42.94	5e-33	123
LLPS-Tru-1513	Triticum urartu	42.86	3e-43	150
LLPS-Tra-2537	Triticum aestivum	42.86	9e-43	150
LLPS-Sob-2305	Sorghum bicolor	42.58	3e-36	132
LLPS-Bro-2457	Brassica oleracea	42.41	1e-33	127
LLPS-Art-2999	Arabidopsis thaliana	42.33	3e-33	124
LLPS-Hov-1407	Hordeum vulgare	42.24	7e-42	148
LLPS-Brr-0003	Brassica rapa	41.72	2e-32	122
LLPS-Orp-2396	Oryza punctata	41.38	2e-37	135
LLPS-Orm-0717	Oryza meridionalis	40.99	3e-39	141
LLPS-Orbr-1876	Oryza brachyantha	40.49	4e-34	126
LLPS-Org-0845	Oryza glaberrima	40.23	1e-35	131
LLPS-Orb-1128	Oryza barthii	40.23	1e-35	131
LLPS-Asg-0985	Ashbya gossypii	40.14	3e-22	95.1
LLPS-Orgl-0385	Oryza glumaepatula	40.12	1e-34	129
LLPS-Zem-1701	Zea mays	39.88	1e-33	125
LLPS-Cym-1104	Cyanidioschyzon merolae	39.86	4e-18	83.2
LLPS-Lep-0222	Leersia perrieri	39.66	6e-36	132
LLPS-Brd-1530	Brachypodium distachyon	39.43	2e-35	130
LLPS-Ors-1732	Oryza sativa	39.08	4e-35	129
LLPS-Orr-2059	Oryza rufipogon	39.08	4e-35	129
LLPS-Orni-2239	Oryza nivara	39.08	4e-35	129
LLPS-Ori-1322	Oryza indica	39.08	4e-35	129
LLPS-Gas-0655	Galdieria sulphuraria	37.75	1e-27	110
LLPS-Tag-1479	Taeniopygia guttata	33.97	2e-14	75.1
LLPS-Anp-0349	Anas platyrhynchos	32.9	6e-15	76.6

LLPS-Dio-3372Pgls

Protein Sequence

Nucleotide Sequence

LLPS-Dio-3372
Pgls