LLPS-Dio-2970
Usp8
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | ubiquitin carboxyl-terminal hydrolase 8 |
| Gene Name: | Usp8 |
| Ensembl Gene: | ENSDORG00000005653.2 |
| Ensembl Protein: | ENSDORP00000018631.1 |
| Organism: | Dipodomys ordii |
| Taxa ID: | 10020 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDORT00000025821.1 | ENSDORP00000018631.1 |
| Ensembl | ENSDORT00000005655.2 | ENSDORP00000005292.2 |
| UniProt | A0A1S3EM05, A0A1S3EM05_DIPOR | |
| RefSeq | , XM_013009959.1 | , XP_012865413.1, XP_012865413.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPAVASVPKE LYLSSSLKDL NKKTEVKPEK ISTKNYVHSA LKIFKAAEEC RLDRDEEKAY 60 61 VLYMKFVSVY NLIKKRSDFK QQQDYYNSMV GLTNIKKAIE EAERLSESLK LRYNHYYEIF 120 121 IKILRLALSK MKKKKINENK ILLQELYTLM MDENTSLIIM DARRTRDYQH SCILNSLSVP 180 181 EEAISPGVTA SRIEANLPDD SKDTWMKRGN VDYVVLLDWF SSAKDLQLGT TLRSLKDALF 240 241 KVSNLRLTIP CNMHEKYKYY LWKLLFFKKQ MLFSLGILVD FTYPSLEEPA PSRPPGQVAP 300 301 PVEVNDKVTL ITVPEERRRA PAKPVAASKA DVSPLIQPGP IIKNIPQIDR TKKPTVKLPE 360 361 DHRIKPESTV LPDRSTKPTF PPVTAMLTDE EKARIHAETA LLMEKNKQEK ELRERQQEEQ 420 421 KEKLMREEQE QKARQKQEAR ENETTESEPK AKEEEERRDG EQARREGKEP SVKRGRELTG 480 481 IKRQSRSEHE MSDAKIPMEG EKRCPTPEMQ KKSTGDVSPL AVSGDASAGK AQREPLTRAR 540 541 SEEMGRIVPG LPSGWAKFLD PITGTFRYYH SPTNTVHMYP PEMAPSSAPP STPPTHKAKP 600 601 QVPAERDREP SKLKRSYSSP DITQAIQEEE KRKPAVTPAV NRENKPTCYP KAEISRLSAS 660 661 QIRNLNPVFG GSGPALTGLR NLGNTCYMNS ILQCLCNAPH LADYFNRNCY QDDINRSNLL 720 721 GHKGEVAEEF GIIMKALWTG QYRYISPRDF KVTIGKINDQ FAGYSQQDSQ ELLLFLMDGL 780 781 HEDLNKADNR KRYKEENNDH LDDFKAAEHA WQKHKQLNES IIVTLFQGQF KSTVQCLTCH 840 841 KKSRTFEAFM YLSLPLASTS KCTLQDCLRL FSKEEKLTDN NRFYCSHCRA RRDSLKKIEI 900 901 WKLPPVLLVH LKRFSYDGRW KQKLQTSVDF PLENLDLSQY VIGPKNSLKK YNLFSVSNHY 960 961 GGLDGGHYTA YCKNAARQRW FKFDDHEVSD ISVGAVRSSA AYILFYTSLG PRAADMAT 1018 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCTGCCG TGGCTTCAGT TCCTAAAGAA CTCTACCTCA GCTCATCCCT GAAAGACCTC 60 61 AACAAGAAAA CTGAAGTTAA ACCAGAGAAA ATAAGCACAA AGAAGTATTT TTTTTTTCCA 120 121 ATTTTAAGCT ATGTGCACAG TGCTCTGAAG ATCTTCAAAG CTGCAGAAGA ATGCAGATTA 180 181 GATCGTGATG AGGAAAAGGC CTATGTGCTA TATATGAAAT TTGTGAGTGT TTATAATCTC 240 241 ATCAAAAAAA GATCTGACTT CAAGCAACAG CAGGACTACT ATAATTCAAT GGTTGGACTC 300 301 ACCAACATCA AAAAAGCTAT TGAAGAAGCT GAAAGACTCT CTGAGAGCCT TAAACTCAGG 360 361 TACAACCATT ATTATGAAAT CTTTATAAAA ATTCTGAGGC TAGCCCTAAG CAAAATGAAA 420 421 AAAAAAAAAA TTAACGAAAA TAAGATATTG CTGCAGGAGC TGTATACACT CATGATGGAT 480 481 GAAAACACCA GCCTGATTAT AATGGATGCG CGAAGAACTC GGGACTACCA GCATTCCTGT 540 541 ATCTTAAATT CACTCAGTGT TCCTGAAGAA GCCATCAGTC CAGGAGTCAC TGCTAGTCGG 600 601 ATTGAAGCAA ACCTCCCGGA TGATTCAAAG GACACATGGA TGAAAAGGGG AAATGTGGAT 660 661 TATGTGGTAC TTCTTGACTG GTTTAGTTCT GCAAAAGATT TACAGCTTGG AACAACTTTA 720 721 CGGAGTCTGA AAGATGCACT TTTCAAGGTT AGCAAGTTTC CTTTGGTAGA GTGCTCGCTG 780 781 AGCAACCATG TGGAATGCCC TAGATTCTAC ACTGATCAAA AAATCAGCAT TGTGGATTTT 840 841 ACTTACCCCT CACTGGAAGA ACCGGCTCCC TCCAGACCTC CTGGCCAGGT TGCTCCTCCT 900 901 GTGGAAGTAA ATGACAAGGT CACCTTGATA ACTGTCCCTG AGGAGAGGAG GAGAGCGCCC 960 961 GCCAAACCAG TCGCTGCTTC CAAAGCGGAT GTTTCACCTC TCATTCAGCC AGGGCCCATT 1020 1021 ATCAAGAACA TTCCACAGAT TGATCGTACT AAAAAACCCA CAGTGAAGTT GCCTGAAGAT 1080 1081 CATAGAATAA AACCTGAAAG TACAGTTCTT CCCGATCGAT CCACCAAACC CACATTTCCC 1140 1141 CCCGTGACCG CCATGTTAAC AGATGAAGAG AAAGCCCGCA TCCATGCAGA AACTGCTCTT 1200 1201 CTAATGGAGA AAAACAAGCA GGAAAAAGAA CTTCGGGAAA GGCAGCAAGA GGAACAGAAG 1260 1261 GAGAAGCTGA TGCGGGAAGA GCAAGAGCAG AAAGCCAGAC AGAAACAAGA AGCTCGAGAA 1320 1321 AATGAGACCA CAGAAAGCGA GCCGAAAGCC AAGGAGGAAG AGGAGAGGAG AGACGGTGAG 1380 1381 CAGGCCAGGA GAGAAGGCAA GGAGCCCTCA GTGAAGAGGG GCAGAGAACT AACAGGAATA 1440 1441 AAAAGACAGA GTAGAAGTGA GCACGAAATG TCTGATGCCA AGATACCTAT GGAGGGAGAG 1500 1501 AAAAGGTGTC CGACTCCGGA AATGCAGAAG AAGTCAACAG GAGATGTGTC TCCTCTAGCT 1560 1561 GTATCGGGAG ATGCCAGTGC AGGCAAGGCG CAGCGTGAGC CCTTGACAAG AGCGCGGAGC 1620 1621 GAGGAAATGG GGAGGATCGT GCCTGGGCTG CCTTCAGGCT GGGCCAAGTT TCTCGACCCA 1680 1681 ATCACAGGGA CCTTCCGCTA CTACCACTCA CCTACCAACA CCGTTCACAT GTATCCACCG 1740 1741 GAGATGGCCC CTTCCTCTGC ACCTCCCTCC ACCCCCCCAA CGCACAAAGC CAAGCCCCAG 1800 1801 GTCCCCGCCG AGCGCGACCG GGAACCCTCC AAGCTGAAGC GCTCCTACTC CTCCCCGGAC 1860 1861 ATCACCCAGG CCATTCAAGA GGAGGAGAAG AGGAAGCCAG CAGTGACCCC AGCAGTGAAT 1920 1921 CGGGAAAACA AGCCAACATG CTACCCCAAA GCTGAGATCT CGAGGCTTTC TGCCTCTCAG 1980 1981 ATTCGGAACC TCAACCCTGT GTTTGGAGGA TCTGGGCCAG CTCTTACTGG ACTTCGTAAT 2040 2041 TTAGGAAACA CTTGTTATAT GAACTCTATA CTGCAGTGCC TCTGTAACGC CCCCCACTTG 2100 2101 GCTGATTATT TCAACAGAAA CTGTTACCAG GATGATATCA ACAGGTCAAA TCTGTTGGGG 2160 2161 CACAAAGGCG AAGTGGCAGA AGAATTTGGA ATAATCATGA AGGCATTGTG GACAGGGCAG 2220 2221 TACAGATACA TCAGCCCAAG AGACTTCAAA GTCACCATTG GGAAGATTAA CGATCAGTTT 2280 2281 GCGGGGTACA GCCAGCAAGA TTCACAAGAG CTGCTCCTCT TCCTCATGGA CGGCCTCCAT 2340 2341 GAAGACCTGA ATAAAGCTGA CAATCGGAAG AGGTATAAAG AAGAAAATAA CGATCATCTT 2400 2401 GATGACTTCA AAGCTGCAGA ACATGCGTGG CAGAAACACA AGCAGCTCAA CGAGTCCATT 2460 2461 ATCGTTACGC TTTTTCAGGG TCAGTTCAAG TCCACAGTAC AGTGCCTCAC CTGCCACAAG 2520 2521 AAGTCGAGGA CGTTTGAGGC CTTTATGTAT CTGTCTCTAC CGCTCGCATC CACGAGTAAA 2580 2581 TGTACATTAC AGGATTGCCT TAGGTTATTT TCCAAAGAAG AAAAACTCAC CGACAACAAC 2640 2641 CGATTTTACT GCAGTCACTG CAGAGCCCGG AGGGACTCCC TGAAGAAGAT TGAAATCTGG 2700 2701 AAGCTGCCGC CGGTGCTTTT AGTGCATCTG AAACGCTTCT CCTATGATGG TAGATGGAAG 2760 2761 CAGAAACTGC AGACGTCCGT GGACTTCCCG TTGGAAAACC TGGACTTGTC ACAGTACGTC 2820 2821 ATTGGTCCAA AGAACAGCTT GAAGAAGTAC AACTTGTTTT CTGTCTCCAA TCACTACGGC 2880 2881 GGCCTGGACG GCGGCCATTA CACGGCCTAC TGCAAGAATG CGGCGCGGCA GCGGTGGTTC 2940 2941 AAGTTCGATG ACCACGAAGT TTCAGACATC TCCGTGGGCG CGGTGAGATC CTCAGCCGCC 3000 3001 TACATCCTCT TCTACACTTC GCTGGGCCCG CGGGCCGCCG ACATGGCCAC ATAG 3054 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Gaga-0335 | Gallus gallus | 91.54 | 0.0 | 645 |
| LLPS-Cas-3066 | Carlito syrichta | 90.27 | 3e-53 | 206 |
| LLPS-Anp-2069 | Anas platyrhynchos | 90.06 | 0.0 | 897 |
| LLPS-Loa-1662 | Loxodonta africana | 87.61 | 4e-50 | 197 |
| LLPS-Fud-2854 | Fukomys damarensis | 85.0 | 9e-51 | 199 |
| LLPS-Ora-0726 | Ornithorhynchus anatinus | 84.96 | 7e-49 | 193 |
| LLPS-Pes-0163 | Pelodiscus sinensis | 84.35 | 2e-50 | 196 |
| LLPS-Meg-1054 | Meleagris gallopavo | 84.07 | 5e-49 | 193 |
| LLPS-Lac-0855 | Latimeria chalumnae | 81.98 | 0.0 | 844 |
| LLPS-Fia-0828 | Ficedula albicollis | 81.42 | 7e-47 | 187 |
| LLPS-Chs-0565 | Chlorocebus sabaeus | 79.1 | 0.0 | 1317 |
| LLPS-Eqc-3493 | Equus caballus | 78.4 | 0.0 | 1352 |
| LLPS-Orc-2602 | Oryctolagus cuniculus | 76.81 | 0.0 | 1505 |
| LLPS-Orn-2564 | Oreochromis niloticus | 76.67 | 0.0 | 788 |
| LLPS-Scf-0499 | Scleropages formosus | 76.36 | 0.0 | 765 |
| LLPS-Leo-1034 | Lepisosteus oculatus | 76.19 | 0.0 | 754 |
| LLPS-Ova-1349 | Ovis aries | 75.71 | 0.0 | 1511 |
| LLPS-Ict-2095 | Ictidomys tridecemlineatus | 75.55 | 0.0 | 1479 |
| LLPS-Xet-0971 | Xenopus tropicalis | 75.5 | 0.0 | 790 |
| LLPS-Xim-1412 | Xiphophorus maculatus | 75.25 | 0.0 | 764 |
| LLPS-Bot-0380 | Bos taurus | 74.86 | 0.0 | 1489 |
| LLPS-Ten-0682 | Tetraodon nigroviridis | 74.65 | 0.0 | 758 |
| LLPS-Hos-2328 | Homo sapiens | 74.6 | 0.0 | 1472 |
| LLPS-Mal-1100 | Mandrillus leucophaeus | 74.6 | 0.0 | 1473 |
| LLPS-Gog-3049 | Gorilla gorilla | 74.6 | 0.0 | 1473 |
| LLPS-Cea-2391 | Cercocebus atys | 74.6 | 0.0 | 1473 |
| LLPS-Maf-0615 | Macaca fascicularis | 74.51 | 0.0 | 1470 |
| LLPS-Aim-2308 | Ailuropoda melanoleuca | 74.46 | 0.0 | 1479 |
| LLPS-Nol-2967 | Nomascus leucogenys | 74.42 | 0.0 | 1467 |
| LLPS-Mam-2574 | Macaca mulatta | 74.42 | 0.0 | 1471 |
| LLPS-Pap-0453 | Pan paniscus | 74.42 | 0.0 | 1475 |
| LLPS-Gaa-1204 | Gasterosteus aculeatus | 74.4 | 0.0 | 756 |
| LLPS-Cap-0999 | Cavia porcellus | 74.38 | 0.0 | 1452 |
| LLPS-Dar-1155 | Danio rerio | 74.34 | 2e-42 | 172 |
| LLPS-Pat-0682 | Pan troglodytes | 74.32 | 0.0 | 1466 |
| LLPS-Ran-2524 | Rattus norvegicus | 74.22 | 0.0 | 1445 |
| LLPS-Aon-4292 | Aotus nancymaae | 74.22 | 0.0 | 1484 |
| LLPS-Poa-3915 | Pongo abelii | 74.15 | 0.0 | 1456 |
| LLPS-Caf-1463 | Canis familiaris | 74.11 | 0.0 | 1468 |
| LLPS-Mea-2417 | Mesocricetus auratus | 74.06 | 0.0 | 1456 |
| LLPS-Caj-1867 | Callithrix jacchus | 73.97 | 0.0 | 1438 |
| LLPS-Mup-1871 | Mustela putorius furo | 73.93 | 0.0 | 1460 |
| LLPS-Fec-0479 | Felis catus | 73.64 | 0.0 | 1465 |
| LLPS-Paa-1472 | Papio anubis | 73.61 | 0.0 | 1466 |
| LLPS-Mum-1143 | Mus musculus | 73.47 | 0.0 | 1444 |
| LLPS-Pof-2461 | Poecilia formosa | 73.45 | 1e-42 | 173 |
| LLPS-Icp-1819 | Ictalurus punctatus | 73.12 | 0.0 | 758 |
| LLPS-Sus-2497 | Sus scrofa | 73.04 | 0.0 | 1478 |
| LLPS-Myl-2317 | Myotis lucifugus | 72.96 | 0.0 | 1439 |
| LLPS-Otg-1664 | Otolemur garnettii | 72.44 | 0.0 | 1435 |
| LLPS-Urm-2212 | Ursus maritimus | 71.95 | 0.0 | 1417 |
| LLPS-Rhb-1891 | Rhinopithecus bieti | 71.84 | 0.0 | 1419 |
| LLPS-Tar-1022 | Takifugu rubripes | 71.68 | 7e-41 | 167 |
| LLPS-Asm-0782 | Astyanax mexicanus | 71.43 | 0.0 | 727 |
| LLPS-Man-0372 | Macaca nemestrina | 70.84 | 0.0 | 1364 |
| LLPS-Orl-1649 | Oryzias latipes | 69.41 | 0.0 | 778 |
| LLPS-Scm-1530 | Scophthalmus maximus | 69.08 | 0.0 | 774 |
| LLPS-Mod-2726 | Monodelphis domestica | 66.25 | 0.0 | 1321 |
| LLPS-Anc-1567 | Anolis carolinensis | 64.98 | 0.0 | 1061 |
| LLPS-Sah-3282 | Sarcophilus harrisii | 64.61 | 0.0 | 1316 |
| LLPS-Tag-2982 | Taeniopygia guttata | 61.69 | 0.0 | 1214 |
| LLPS-Abg-0315 | Absidia glauca | 52.51 | 2e-52 | 204 |
| LLPS-Sem-2137 | Selaginella moellendorffii | 51.1 | 1e-49 | 190 |
| LLPS-Cii-2135 | Ciona intestinalis | 50.13 | 9e-127 | 419 |
| LLPS-Mua-1442 | Musa acuminata | 49.5 | 2e-51 | 200 |
| LLPS-Cis-1504 | Ciona savignyi | 47.9 | 3e-119 | 397 |
| LLPS-Put-1289 | Puccinia triticina | 45.8 | 2e-71 | 263 |
| LLPS-Drm-0748 | Drosophila melanogaster | 45.08 | 4e-90 | 314 |
| LLPS-Tum-1613 | Tuber melanosporum | 40.4 | 1e-80 | 290 |
| LLPS-Mel-1506 | Melampsora laricipopulina | 40.18 | 9e-72 | 263 |
| LLPS-Crn-0042 | Cryptococcus neoformans | 40.17 | 5e-76 | 277 |
| LLPS-Miv-1501 | Microbotryum violaceum | 40.11 | 2e-79 | 287 |
| LLPS-Brr-0733 | Brassica rapa | 39.1 | 4e-59 | 216 |
| LLPS-Brn-1110 | Brassica napus | 39.1 | 9e-60 | 218 |
| LLPS-Bro-0132 | Brassica oleracea | 38.21 | 4e-58 | 214 |
| LLPS-Spr-0486 | Sporisorium reilianum | 37.05 | 2e-69 | 256 |
| LLPS-Yal-0826 | Yarrowia lipolytica | 36.63 | 2e-64 | 239 |
| LLPS-Usm-1191 | Ustilago maydis | 35.99 | 8e-73 | 266 |
| LLPS-Scj-0776 | Schizosaccharomyces japonicus | 35.92 | 5e-50 | 191 |
| LLPS-Sac-0933 | Saccharomyces cerevisiae | 35.26 | 6e-53 | 204 |
| LLPS-Pug-1167 | Puccinia graminis | 35.12 | 1e-58 | 224 |
| LLPS-Asg-0962 | Ashbya gossypii | 34.99 | 1e-54 | 209 |
| LLPS-Cae-0397 | Caenorhabditis elegans | 33.82 | 6e-53 | 203 |
| LLPS-Kop-1439 | Komagataella pastoris | 33.24 | 8e-50 | 193 |
| LLPS-Asni-1337 | Aspergillus niger | 32.78 | 2e-51 | 199 |
| LLPS-Lem-0841 | Leptosphaeria maculans | 32.26 | 8e-56 | 214 |
| LLPS-Asfu-0783 | Aspergillus fumigatus | 32.22 | 1e-50 | 199 |
| LLPS-Asc-0821 | Aspergillus clavatus | 32.14 | 1e-51 | 201 |
| LLPS-Ast-0351 | Aspergillus terreus | 31.77 | 2e-50 | 197 |
| LLPS-Aso-1059 | Aspergillus oryzae | 31.32 | 1e-50 | 197 |
| LLPS-Asf-0785 | Aspergillus flavus | 31.04 | 2e-51 | 199 |
| LLPS-Nef-1067 | Neosartorya fischeri | 30.82 | 6e-51 | 199 |
| LLPS-Pytr-0138 | Pyrenophora triticirepentis | 30.49 | 2e-52 | 204 |
| LLPS-Asn-0486 | Aspergillus nidulans | 30.49 | 5e-50 | 196 |