• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-2837
Tnrc6a

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: trinucleotide repeat-containing gene 6A protein isoform X1
Gene Name: Tnrc6a
Ensembl Gene: ENSDORG00000029374.1
Ensembl Protein: ENSDORP00000019601.1
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granule, Chromatoid bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFGVGNTAAQ  PRGMQQPPAQ  PLSSSQPNLR  AQVPPPLLSP  QVPVSLLKYA  PNNGGLNPLF  60
61    GPQQVAMLNQ  LSQLNQLSQI  SQLQRLLAQQ  QRAQSQRSVP  SGNRQQQEQQ  SRPLSVQQQM  120
121   MQQSRQLDPN  LLVKQQTPPS  QQQSLHQPAM  KSFLDNVMPH  TTPELQKGPS  PINAFSNFPI  180
181   GLNSNLNVNM  DVNSIKEPQS  RLRKWTTVDS  ISVNTSLDQN  SSKHGAISSG  FRLEESPFVP  240
241   YDFMNSSTSP  ASPPGSIGDG  WPRAKSPNGS  SSVNWPPEFR  PGEPWKGYPN  IDPETDPYVT  300
301   PGSVINNLSI  NTVREVDHLR  DRNSGSSSSL  NTTLPSTSAW  SSIRASNYNV  PLSSTAQSTS  360
361   ARNSDSKLTW  SPGSVTNTSL  AHELWKVPLP  PKSITAPSRP  PPGLTGQKPP  LSTWDNSPLR  420
421   VGGGWGNSDA  RYTPGSSWGE  SSSGRITNWL  VLKNLTPQID  GSTLRTLCMQ  HGPLITFHLN  480
481   LPHGNALVRY  SSKEEVVKAQ  KSLHMCVLGN  TTILAEFASE  EEISRFFAQS  QSLTPSPGWQ  540
541   SLGSSQSRLG  SLDCSHAFSS  RTDLNHWNGA  ALSGANCGDL  HGTSLWGTPH  YATSLWAPPS  600
601   SSDPRGISSP  SPINAFLSVD  HLGGGGESM  629
Nucleotide CDS Sequence (FASTA)
1     ATGTTTGGTG  TTGGAAACAC  AGCAGCACAA  CCCCGGGGCA  TGCAGCAGCC  TCCAGCACAA  60
61    CCTCTTAGTT  CATCTCAGCC  TAATCTCCGT  GCTCAAGTGC  CTCCTCCATT  ACTCTCCCCT  120
121   CAGGTTCCAG  TTTCATTGCT  GAAGTATGCA  CCAAACAACG  GTGGCCTGAA  CCCGCTCTTT  180
181   GGCCCTCAGC  AGGTAGCCAT  GCTGAACCAG  CTCTCCCAGC  TAAACCAGCT  TTCTCAGATC  240
241   TCCCAGTTAC  AGCGATTGTT  AGCGCAGCAG  CAAAGGGCGC  AGAGTCAGAG  AAGCGTGCCT  300
301   TCTGGTAACC  GGCAGCAGCA  AGAACAGCAG  AGTCGGCCTC  TCAGTGTGCA  GCAGCAAATG  360
361   ATGCAGCAGT  CTCGCCAGCT  GGATCCCAAC  CTGTTGGTGA  AGCAACAGAC  GCCGCCATCC  420
421   CAGCAGCAAT  CCCTCCATCA  GCCAGCCATG  AAGTCTTTCC  TCGACAATGT  CATGCCCCAC  480
481   ACTACACCGG  AGCTGCAAAA  AGGGCCATCA  CCAATCAATG  CTTTCAGCAA  CTTTCCTATA  540
541   GGCTTGAACT  CAAACTTGAA  TGTAAATATG  GATGTGAACA  GTATTAAAGA  GCCGCAGTCA  600
601   AGACTAAGGA  AGTGGACTAC  AGTGGACAGC  ATTTCTGTGA  ACACATCTTT  GGATCAGAAC  660
661   TCCAGCAAAC  ATGGTGCTAT  TTCAAGTGGT  TTCAGGCTGG  AAGAGTCTCC  ATTTGTTCCC  720
721   TATGACTTTA  TGAACAGCAG  TACTTCACCA  GCCAGTCCTC  CGGGTTCAAT  AGGAGATGGC  780
781   TGGCCACGTG  CCAAATCGCC  TAATGGCTCT  AGCAGTGTTA  ATTGGCCACC  AGAATTTCGC  840
841   CCTGGTGAAC  CATGGAAAGG  TTATCCAAAC  ATTGACCCCG  AAACTGACCC  TTACGTCACT  900
901   CCTGGCAGTG  TCATAAACAA  TCTTTCAATT  AATACTGTGC  GGGAAGTCGA  CCACCTCAGG  960
961   GACAGGAACA  GTGGGTCATC  CTCATCCTTG  AACACCACGC  TGCCTTCAAC  TAGTGCCTGG  1020
1021  TCATCCATTC  GTGCCTCCAA  CTACAATGTT  CCCCTCAGCA  GTACAGCACA  AAGCACTTCA  1080
1081  GCCAGAAATA  GTGATTCCAA  ATTGACGTGG  TCTCCTGGTT  CAGTTACAAA  CACATCTCTG  1140
1141  GCTCATGAGC  TGTGGAAGGT  CCCTCTGCCA  CCTAAAAGCA  TCACTGCTCC  ATCCCGCCCG  1200
1201  CCTCCGGGAC  TGACTGGTCA  GAAGCCACCC  TTGTCTACGT  GGGATAACTC  TCCCCTTCGA  1260
1261  GTAGGAGGAG  GATGGGGGAA  TTCTGATGCC  AGATATACCC  CAGGTTCCAG  CTGGGGTGAG  1320
1321  AGCAGCTCAG  GGAGAATAAC  AAATTGGCTT  GTTCTGAAAA  ACCTTACACC  TCAGATCGAC  1380
1381  GGCTCAACTC  TGCGAACCCT  GTGCATGCAG  CATGGCCCGC  TGATAACATT  CCACCTGAAC  1440
1441  CTCCCCCACG  GAAATGCTCT  GGTCCGCTAC  AGTTCAAAAG  AAGAGGTAGT  GAAGGCACAA  1500
1501  AAGTCTCTGC  ACATGTGTGT  ACTGGGGAAC  ACTACTATTC  TTGCTGAGTT  TGCCAGTGAA  1560
1561  GAGGAGATCA  GTCGTTTCTT  TGCACAAAGT  CAGTCTCTGA  CCCCTTCTCC  CGGCTGGCAG  1620
1621  TCGCTTGGGT  CCAGCCAGAG  CCGGCTGGGC  TCTCTCGACT  GCTCCCACGC  ATTCTCCAGC  1680
1681  CGGACCGACC  TCAATCACTG  GAATGGTGCT  GCGCTGTCGG  GAGCTAACTG  TGGAGACCTT  1740
1741  CACGGCACTT  CCCTCTGGGG  GACCCCGCAC  TACGCCACAA  GCCTGTGGGC  GCCTCCGAGC  1800
1801  AGCAGCGACC  CCCGGGGAAT  TAGCAGCCCA  TCCCCCATTA  ACGCTTTTCT  TTCTGTTGAC  1860
1861  CACCTGGGTG  GGGGTGGAGA  GTCCATGTGA  1890

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gog-2593Gorilla gorilla98.090.0 957
LLPS-Chs-0212Chlorocebus sabaeus98.090.0 957
LLPS-Sus-3220Sus scrofa98.090.0 957
LLPS-Otg-1101Otolemur garnettii98.090.0 954
LLPS-Hos-0196Homo sapiens98.090.0 957
LLPS-Pat-4848Pan troglodytes98.090.0 957
LLPS-Urm-0827Ursus maritimus98.090.0 955
LLPS-Cas-3430Carlito syrichta98.090.0 951
LLPS-Poa-4062Pongo abelii98.090.0 959
LLPS-Caf-3273Canis familiaris98.090.0 957
LLPS-Mam-3132Macaca mulatta98.090.0 959
LLPS-Orc-3876Oryctolagus cuniculus97.940.0 950
LLPS-Aim-4355Ailuropoda melanoleuca97.930.0 954
LLPS-Ova-3268Ovis aries97.930.0 952
LLPS-Pap-1147Pan paniscus97.930.0 955
LLPS-Man-2954Macaca nemestrina97.930.0 977
LLPS-Ict-3015Ictidomys tridecemlineatus97.770.0 954
LLPS-Bot-1043Bos taurus97.620.0 949
LLPS-Cap-2283Cavia porcellus97.620.0 948
LLPS-Ran-3774Rattus norvegicus97.270.0 949
LLPS-Fec-4120Felis catus97.140.0 949
LLPS-Mum-3069Mus musculus96.980.0 959
LLPS-Myl-1503Myotis lucifugus96.820.0 949
LLPS-Cea-3563Cercocebus atys96.350.0 941
LLPS-Maf-3602Macaca fascicularis96.20.0 939
LLPS-Rhb-4713Rhinopithecus bieti96.20.0 940
LLPS-Caj-4577Callithrix jacchus95.230.0 954
LLPS-Aon-2611Aotus nancymaae95.230.0 954
LLPS-Loa-0917Loxodonta africana94.130.0 971
LLPS-Eqc-3903Equus caballus93.970.0 947
LLPS-Fud-4054Fukomys damarensis93.80.0 906
LLPS-Mea-4466Mesocricetus auratus93.650.0 956
LLPS-Ora-1545Ornithorhynchus anatinus93.480.0 891
LLPS-Anp-2428Anas platyrhynchos92.860.0 858
LLPS-Nol-2354Nomascus leucogenys92.740.0 911
LLPS-Tag-2693Taeniopygia guttata92.370.0 854
LLPS-Fia-1046Ficedula albicollis92.220.0 851
LLPS-Gaga-2968Gallus gallus92.080.0 860
LLPS-Paa-2915Papio anubis90.140.0 841
LLPS-Mod-4325Monodelphis domestica89.470.0 904
LLPS-Sah-0723Sarcophilus harrisii89.160.0 898
LLPS-Mup-0906Mustela putorius furo88.130.0 820
LLPS-Leo-2679Lepisosteus oculatus82.780.0 653
LLPS-Lac-0840Latimeria chalumnae80.030.0 756
LLPS-Xet-0826Xenopus tropicalis79.650.0 753
LLPS-Dar-3653Danio rerio71.810.0 670
LLPS-Asm-0767Astyanax mexicanus71.230.0 610
LLPS-Anc-3399Anolis carolinensis71.180.0 615
LLPS-Icp-2550Ictalurus punctatus70.831e-171 539
LLPS-Scf-0282Scleropages formosus67.660.0 670
LLPS-Meg-0395Meleagris gallopavo60.813e-64 236
LLPS-Scm-0459Scophthalmus maximus60.451e-162 517
LLPS-Gaa-0008Gasterosteus aculeatus60.434e-159 505
LLPS-Orn-3420Oreochromis niloticus60.02e-156 499
LLPS-Pof-0978Poecilia formosa59.345e-151 484
LLPS-Tar-2643Takifugu rubripes58.219e-154 492
LLPS-Orl-0915Oryzias latipes49.171e-97 334
LLPS-Mal-4182Mandrillus leucophaeus48.591e-96 332
LLPS-Xim-1654Xiphophorus maculatus48.291e-89 311
LLPS-Pes-3561Pelodiscus sinensis46.393e-101 343
LLPS-Tut-0994Tursiops truncatus45.911e-100 342
LLPS-Ten-0782Tetraodon nigroviridis45.282e-82 290
LLPS-Drm-0173Drosophila melanogaster34.724e-34 143
LLPS-Cii-0970Ciona intestinalis28.059e-1889.0