• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-1261
Cdk7

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: cyclin-dependent kinase 7
Gene Name: Cdk7
Ensembl Gene: ENSDORG00000026411.1
Ensembl Protein: ENSDORP00000019533.1
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Cajal body, Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     DNSLVLTPSH  IKAYVLMTLQ  GLEYLHQHWI  LHRDLKPNNL  LLDENGVLKL  ADFGLAKSFG  60
61    SPNRAYTHQV  VTRWYRAPEL  LFGARMYGVG  VDMWAVGCIL  AELLLRVPFL  PGDSDLDQLT  120
121   RIFETLGTPT  EEQWPDMCSL  PDYVTFKSFP  GIPLQHIFIA  AGDDLLELIQ  GLFLFNPCTR  180
181   ITASQALKTK  YFSNRPGPTP  GCQLPRPNCP  VETLKEQSNP  AMATKRKRTE  GLEQGGLPKK  240
241   LIF  243
Nucleotide CDS Sequence (FASTA)
1     GATAATAGTC  TTGTGCTGAC  ACCTTCTCAC  ATTAAAGCAT  ATGTGTTGAT  GACTCTTCAA  60
61    GGGTTAGAAT  ATTTACATCA  GCATTGGATT  CTACATAGGG  ATCTAAAACC  AAACAATTTG  120
121   TTGCTAGATG  AAAATGGAGT  GCTAAAACTG  GCAGATTTTG  GCCTGGCCAA  ATCATTTGGG  180
181   AGCCCTAATA  GAGCATATAC  ACATCAAGTT  GTAACCAGAT  GGTATCGGGC  CCCTGAGTTG  240
241   CTATTTGGAG  CTAGGATGTA  TGGTGTGGGT  GTGGATATGT  GGGCTGTTGG  CTGCATATTA  300
301   GCAGAATTGC  TTCTAAGGGT  ACCTTTTCTG  CCAGGAGACT  CAGATCTTGA  TCAGCTAACA  360
361   AGAATATTTG  AAACTTTGGG  CACACCTACT  GAGGAGCAGT  GGCCTGACAT  GTGCAGTCTT  420
421   CCTGATTACG  TGACATTTAA  GAGTTTCCCT  GGGATCCCAT  TACAACACAT  CTTCATTGCC  480
481   GCAGGAGATG  ACTTGCTTGA  ACTAATACAA  GGCTTATTCT  TATTCAATCC  TTGCACTCGA  540
541   ATTACAGCCT  CACAGGCATT  GAAGACGAAG  TACTTCAGTA  ACCGGCCAGG  TCCAACCCCT  600
601   GGTTGTCAGC  TGCCAAGACC  AAACTGTCCA  GTGGAGACAT  TAAAGGAACA  GTCCAATCCA  660
661   GCCATGGCAA  CAAAACGGAA  ACGAACAGAG  GGCTTAGAGC  AAGGAGGATT  GCCTAAGAAG  720
721   CTGATTTTTT  AG  732

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-0151Ictidomys tridecemlineatus98.352e-179 504
LLPS-Orc-1418Oryctolagus cuniculus97.947e-178 500
LLPS-Otg-3034Otolemur garnettii97.539e-178 499
LLPS-Ran-0193Rattus norvegicus97.532e-177 499
LLPS-Sus-2344Sus scrofa97.124e-177 498
LLPS-Urm-2264Ursus maritimus96.716e-177 498
LLPS-Fec-1797Felis catus96.716e-177 498
LLPS-Caf-0877Canis familiaris96.716e-176 495
LLPS-Bot-0678Bos taurus96.711e-176 497
LLPS-Tut-1122Tursiops truncatus96.712e-176 496
LLPS-Aim-3789Ailuropoda melanoleuca96.716e-177 498
LLPS-Ova-3530Ovis aries96.711e-176 497
LLPS-Myl-3594Myotis lucifugus96.716e-177 498
LLPS-Eqc-3675Equus caballus96.66e-168 476
LLPS-Man-4616Macaca nemestrina96.33e-175 493
LLPS-Loa-3518Loxodonta africana96.37e-176 495
LLPS-Mam-1604Macaca mulatta96.33e-175 493
LLPS-Cea-0866Cercocebus atys96.33e-175 493
LLPS-Maf-2306Macaca fascicularis96.33e-175 493
LLPS-Chs-1552Chlorocebus sabaeus96.33e-175 493
LLPS-Mup-0468Mustela putorius furo96.32e-176 496
LLPS-Hos-0677Homo sapiens95.882e-174 491
LLPS-Pat-2199Pan troglodytes95.882e-174 491
LLPS-Pap-2605Pan paniscus95.882e-174 491
LLPS-Rhb-2905Rhinopithecus bieti95.882e-174 491
LLPS-Poa-0645Pongo abelii95.887e-174 490
LLPS-Aon-2322Aotus nancymaae95.881e-174 492
LLPS-Caj-2343Callithrix jacchus95.881e-174 492
LLPS-Gog-0950Gorilla gorilla95.882e-174 491
LLPS-Mal-0416Mandrillus leucophaeus95.882e-174 491
LLPS-Mum-0585Mus musculus95.471e-173 489
LLPS-Fud-2655Fukomys damarensis95.472e-173 488
LLPS-Sah-1133Sarcophilus harrisii95.193e-130 377
LLPS-Cas-0219Carlito syrichta94.656e-162 459
LLPS-Mod-1649Monodelphis domestica93.422e-170 481
LLPS-Mea-1783Mesocricetus auratus92.663e-119 346
LLPS-Cap-1730Cavia porcellus90.958e-161 456
LLPS-Ora-1736Ornithorhynchus anatinus89.744e-147 421
LLPS-Fia-3184Ficedula albicollis87.651e-157 448
LLPS-Anp-1240Anas platyrhynchos87.611e-153 436
LLPS-Pes-2589Pelodiscus sinensis86.838e-152 434
LLPS-Tag-0161Taeniopygia guttata86.423e-143 412
LLPS-Gaga-2126Gallus gallus85.191e-151 433
LLPS-Anc-0365Anolis carolinensis84.771e-150 431
LLPS-Lac-0143Latimeria chalumnae84.655e-118 343
LLPS-Nol-3059Nomascus leucogenys84.46e-150 429
LLPS-Xet-2394Xenopus tropicalis84.362e-151 433
LLPS-Paa-2438Papio anubis83.673e-144 414
LLPS-Leo-2323Lepisosteus oculatus82.727e-145 416
LLPS-Scf-1551Scleropages formosus81.073e-146 420
LLPS-Dar-0031Danio rerio80.662e-144 415
LLPS-Icp-3690Ictalurus punctatus79.841e-143 413
LLPS-Orl-1265Oryzias latipes78.973e-135 393
LLPS-Pof-3571Poecilia formosa78.65e-143 412
LLPS-Asm-1326Astyanax mexicanus78.192e-136 395
LLPS-Orn-3395Oreochromis niloticus77.782e-140 405
LLPS-Gaa-1387Gasterosteus aculeatus77.787e-139 401
LLPS-Xim-2011Xiphophorus maculatus77.781e-141 408
LLPS-Scm-2694Scophthalmus maximus77.144e-137 398
LLPS-Ten-2146Tetraodon nigroviridis77.056e-138 399
LLPS-Tar-3266Takifugu rubripes77.053e-137 397
LLPS-Cii-1190Ciona intestinalis65.981e-113 337
LLPS-Drm-1433Drosophila melanogaster63.016e-109 325
LLPS-Brr-0399Brassica rapa58.451e-85 267
LLPS-Gor-0740Gossypium raimondii58.457e-86 268
LLPS-Thc-0037Theobroma cacao58.172e-81 257
LLPS-Orbr-0072Oryza brachyantha57.491e-83 261
LLPS-Dac-1216Daucus carota57.499e-85 265
LLPS-Lep-0113Leersia perrieri57.493e-84 264
LLPS-Orp-1226Oryza punctata57.02e-81 260
LLPS-Orm-0472Oryza meridionalis57.04e-83 261
LLPS-Orr-0758Oryza rufipogon57.04e-83 261
LLPS-Org-0931Oryza glaberrima57.03e-83 261
LLPS-Orb-1615Oryza barthii57.05e-84 260
LLPS-Ori-0634Oryza indica57.04e-83 261
LLPS-Orni-1538Oryza nivara57.05e-83 261
LLPS-Orgl-0946Oryza glumaepatula57.03e-83 261
LLPS-Cae-0633Caenorhabditis elegans56.733e-80 251
LLPS-Hov-0702Hordeum vulgare56.731e-82 260
LLPS-Tra-2312Triticum aestivum56.731e-82 260
LLPS-Hea-0735Helianthus annuus56.689e-86 268
LLPS-Art-2083Arabidopsis thaliana56.525e-86 268
LLPS-Sob-1547Sorghum bicolor56.521e-82 260
LLPS-Zem-0774Zea mays56.522e-82 259
LLPS-Arl-1916Arabidopsis lyrata56.527e-86 267
LLPS-Sei-1689Setaria italica56.521e-81 258
LLPS-Bro-2061Brassica oleracea56.51e-87 270
LLPS-Brn-1795Brassica napus56.51e-87 270
LLPS-Cus-1201Cucumis sativus56.423e-86 269
LLPS-Amt-1558Amborella trichopoda56.362e-85 267
LLPS-Php-2046Physcomitrella patens56.197e-82 258
LLPS-Glm-1202Glycine max56.165e-86 267
LLPS-Sem-0012Selaginella moellendorffii55.815e-85 265
LLPS-Phv-1197Phaseolus vulgaris55.717e-85 265
LLPS-Vir-0595Vigna radiata55.718e-85 265
LLPS-Viv-1805Vitis vinifera55.612e-83 262
LLPS-Coc-0907Corchorus capsularis55.456e-86 266
LLPS-Met-1621Medicago truncatula55.452e-82 259
LLPS-Abg-0763Absidia glauca55.342e-82 256
LLPS-Prp-2455Prunus persica55.32e-84 264
LLPS-Mae-0795Manihot esculenta55.259e-86 268
LLPS-Via-1318Vigna angularis55.251e-84 265
LLPS-Gas-1330Galdieria sulphuraria55.054e-77 243
LLPS-Pot-0253Populus trichocarpa54.892e-82 259
LLPS-Scj-0694Schizosaccharomyces japonicus53.855e-73 232
LLPS-Brd-1177Brachypodium distachyon53.718e-83 260
LLPS-Scp-1262Schizosaccharomyces pombe53.372e-71 228
LLPS-Pug-0733Puccinia graminis53.143e-76 242
LLPS-Miv-0781Microbotryum violaceum53.084e-73 236
LLPS-Osl-1177Ostreococcus lucimarinus52.433e-75 239
LLPS-Scc-0054Schizosaccharomyces cryophilus52.41e-69 223
LLPS-Mua-1555Musa acuminata52.032e-85 268
LLPS-Chc-0548Chondrus crispus51.811e-67 219
LLPS-Cym-0998Cyanidioschyzon merolae51.521e-63 208
LLPS-Coo-0249Colletotrichum orbiculare51.042e-58 197
LLPS-Fus-0197Fusarium solani50.541e-59 197
LLPS-Sol-1596Solanum lycopersicum50.26e-84 263
LLPS-Sot-0643Solanum tuberosum50.26e-84 263
LLPS-Kop-1501Komagataella pastoris50.02e-65 212
LLPS-Usm-0408Ustilago maydis49.793e-80 252
LLPS-Spr-1146Sporisorium reilianum49.584e-76 242
LLPS-Mel-0813Melampsora laricipopulina49.584e-79 249
LLPS-Mao-1007Magnaporthe oryzae49.56e-59 196
LLPS-Fuv-1095Fusarium verticillioides49.469e-58 192
LLPS-Map-0544Magnaporthe poae49.253e-59 196
LLPS-Trr-0092Trichoderma reesei49.241e-58 195
LLPS-Ors-0422Oryza sativa48.926e-59 197
LLPS-Gag-1227Gaeumannomyces graminis48.762e-58 194
LLPS-Yal-0965Yarrowia lipolytica48.688e-59 195
LLPS-Crn-0512Cryptococcus neoformans48.426e-59 195
LLPS-Nec-0542Neurospora crassa48.245e-59 196
LLPS-Cogr-0648Colletotrichum graminicola48.064e-59 196
LLPS-Ved-0119Verticillium dahliae48.021e-59 197
LLPS-Sac-0892Saccharomyces cerevisiae48.026e-63 205
LLPS-Beb-0183Beauveria bassiana47.963e-60 199
LLPS-Asg-0860Ashbya gossypii47.876e-65 211
LLPS-Tum-0229Tuber melanosporum47.643e-58 195
LLPS-Trv-0927Trichoderma virens47.426e-59 196
LLPS-Asc-0828Aspergillus clavatus47.421e-58 195
LLPS-Zyt-0548Zymoseptoria tritici47.292e-61 202
LLPS-Asni-1019Aspergillus niger46.75e-59 197
LLPS-Ere-0279Erinaceus europaeus46.673e-58 193
LLPS-Asn-0885Aspergillus nidulans46.117e-58 193
LLPS-Meg-0197Meleagris gallopavo45.591e-57 192
LLPS-Nef-0156Neosartorya fischeri44.812e-58 196
LLPS-Asfu-0475Aspergillus fumigatus44.812e-58 196