• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-0777
Pard6a

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: partitioning defective 6 homolog alpha
Gene Name: Pard6a
Ensembl Gene: ENSDORG00000000114.2
Ensembl Protein: ENSDORP00000000102.2
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MARPQRTPAR  SPDSIVEVKS  KFDAEFRRFA  LPRASVSGFQ  EFSRLLRAVH  QIPGLDVLLG  60
61    YTDAHGDLLP  LTNDDSLHRA  LASGPPPLRL  LVQKREADSS  GLAFASNSLQ  RRKKGLLLRP  120
121   VASLRTRPPL  LISLPQDFRQ  VSSVIDVDLL  PETHRRVRLH  KHGSDRPLGF  YIRDGMSMRV  180
181   APQGLERVPG  IFISRLVRGG  LAESTGLLAV  SDEILEVNGI  EVAGKTLDQV  TDMMVANSHN  240
241   LIVTVKPANQ  RNNVVRGASG  RLTRPPSTGP  GPAEADSDDD  TSDLVMENRH  PSCSNGLSQG  300
301   SPCWDLQPGC  LLPGIGSSLP  SLNGQEQTSS  VWGSGIRGDG  SGFSL  345
Nucleotide CDS Sequence (FASTA)
1     ATGGCCAGGC  CGCAGCGGAC  TCCAGCACGC  AGTCCCGACA  GCATCGTCGA  GGTGAAGAGC  60
61    AAATTTGACG  CTGAGTTCCG  ACGCTTTGCG  CTGCCCCGCG  CTTCGGTGAG  TGGCTTCCAA  120
121   GAGTTCTCGA  GGTTGCTGCG  TGCGGTACAC  CAGATCCCAG  GCCTGGACGT  GCTGCTTGGT  180
181   TATACGGATG  CTCATGGTGA  CTTGCTGCCC  CTCACCAACG  ATGACAGCCT  GCACCGGGCC  240
241   CTGGCCAGCG  GGCCCCCACC  ACTACGTCTA  CTAGTGCAGA  AGCGGGAAGC  AGACTCCAGT  300
301   GGCCTGGCTT  TTGCATCCAA  CTCCCTGCAA  CGGCGTAAGA  AAGGGCTCCT  GCTGCGGCCA  360
361   GTGGCATCCC  TACGCACCCG  GCCACCCTTG  CTAATCAGCT  TGCCCCAAGA  TTTCCGCCAG  420
421   GTCTCTTCAG  TCATAGATGT  GGACCTACTG  CCTGAAACCC  ATCGACGGGT  GCGACTGCAC  480
481   AAGCATGGTT  CAGACCGCCC  CCTGGGCTTC  TATATCCGAG  ATGGCATGAG  CATGCGTGTG  540
541   GCTCCCCAGG  GCCTGGAGCG  GGTCCCAGGC  ATCTTCATCT  CCCGCCTGGT  ACGTGGGGGC  600
601   CTGGCTGAGA  GTACAGGGCT  ACTGGCAGTC  AGTGATGAGA  TCCTCGAGGT  TAATGGCATT  660
661   GAGGTGGCTG  GCAAGACTTT  GGACCAAGTA  ACAGACATGA  TGGTCGCCAA  CAGCCATAAC  720
721   CTCATTGTCA  CTGTCAAGCC  TGCCAACCAG  CGCAATAATG  TGGTGCGAGG  GGCATCTGGG  780
781   CGTCTAACAA  GGCCACCATC  TACAGGGCCT  GGGCCTGCTG  AGGCGGACAG  TGATGATGAC  840
841   ACCAGTGACC  TGGTCATGGA  GAATCGCCAC  CCTTCCTGTT  CTAATGGGCT  GTCTCAGGGG  900
901   TCTCCATGCT  GGGACCTGCA  ACCTGGCTGC  CTACTTCCTG  GTATTGGTAG  CTCTCTGCCT  960
961   TCCCTGAATG  GCCAGGAGCA  GACCAGCTCT  GTCTGGGGGA  GTGGCATTCG  AGGAGATGGT  1020
1021  AGTGGCTTCA  GCCTCTGA  1038

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-2711Ictidomys tridecemlineatus94.220.0 591
LLPS-Poa-2640Pongo abelii93.640.0 591
LLPS-Pap-2998Pan paniscus93.640.0 591
LLPS-Hos-1863Homo sapiens93.640.0 591
LLPS-Eqc-0417Equus caballus93.350.0 593
LLPS-Pat-2134Pan troglodytes93.060.0 585
LLPS-Man-1102Macaca nemestrina93.040.0 586
LLPS-Cap-3748Cavia porcellus92.770.0 586
LLPS-Aim-2248Ailuropoda melanoleuca92.770.0 609
LLPS-Mal-0559Mandrillus leucophaeus92.770.0 582
LLPS-Paa-1536Papio anubis92.770.0 582
LLPS-Maf-1771Macaca fascicularis92.770.0 582
LLPS-Mam-2335Macaca mulatta92.750.0 587
LLPS-Caf-1556Canis familiaris92.750.0 611
LLPS-Nol-1868Nomascus leucogenys92.490.0 584
LLPS-Rhb-0655Rhinopithecus bieti92.490.0 580
LLPS-Sus-2083Sus scrofa92.490.0 584
LLPS-Chs-1082Chlorocebus sabaeus92.490.0 580
LLPS-Gog-1004Gorilla gorilla92.490.0 595
LLPS-Fec-1881Felis catus92.20.0 585
LLPS-Caj-1438Callithrix jacchus92.20.0 580
LLPS-Bot-2216Bos taurus91.910.0 584
LLPS-Mup-2194Mustela putorius furo91.910.0 583
LLPS-Mum-0299Mus musculus91.620.0 574
LLPS-Fud-3744Fukomys damarensis91.350.0 572
LLPS-Orc-0040Oryctolagus cuniculus91.330.0 597
LLPS-Otg-0386Otolemur garnettii91.330.0 590
LLPS-Ova-2038Ovis aries91.330.0 578
LLPS-Aon-4105Aotus nancymaae91.330.0 594
LLPS-Mea-0094Mesocricetus auratus91.330.0 571
LLPS-Ran-2813Rattus norvegicus91.30.0 577
LLPS-Myl-1262Myotis lucifugus90.860.0 597
LLPS-Tut-1108Tursiops truncatus90.830.0 562
LLPS-Loa-0289Loxodonta africana89.880.0 577
LLPS-Urm-3367Ursus maritimus89.860.0 566
LLPS-Ora-1134Ornithorhynchus anatinus80.489e-149 432
LLPS-Cea-2167Cercocebus atys78.327e-169 481
LLPS-Mod-0468Monodelphis domestica76.623e-175 498
LLPS-Sah-0615Sarcophilus harrisii71.157e-105 315
LLPS-Pes-2041Pelodiscus sinensis70.542e-106 319
LLPS-Asm-1422Astyanax mexicanus70.382e-129 383
LLPS-Gaga-0824Gallus gallus68.658e-138 403
LLPS-Tag-2715Taeniopygia guttata68.442e-128 377
LLPS-Lac-3035Latimeria chalumnae68.073e-73 234
LLPS-Leo-1438Lepisosteus oculatus67.181e-114 345
LLPS-Anc-0750Anolis carolinensis67.06e-132 387
LLPS-Scf-2981Scleropages formosus66.542e-113 341
LLPS-Gaa-2849Gasterosteus aculeatus65.833e-107 326
LLPS-Scm-1649Scophthalmus maximus65.134e-112 339
LLPS-Orn-2594Oreochromis niloticus65.126e-120 359
LLPS-Anp-0832Anas platyrhynchos64.691e-125 372
LLPS-Orl-2308Oryzias latipes64.233e-111 337
LLPS-Icp-3275Ictalurus punctatus64.174e-105 321
LLPS-Dar-2403Danio rerio63.61e-110 334
LLPS-Fia-3434Ficedula albicollis63.146e-103 314
LLPS-Xim-1561Xiphophorus maculatus63.081e-108 330
LLPS-Pof-3033Poecilia formosa62.893e-104 319
LLPS-Tar-1891Takifugu rubripes62.267e-108 327
LLPS-Meg-1008Meleagris gallopavo62.246e-103 315
LLPS-Ten-0011Tetraodon nigroviridis61.623e-113 338
LLPS-Drm-2173Drosophila melanogaster57.969e-88 275
LLPS-Cae-0327Caenorhabditis elegans56.929e-89 276
LLPS-Xet-1427Xenopus tropicalis56.041e-100 309
LLPS-Cii-1054Ciona intestinalis52.899e-75 242
LLPS-Cas-1035Carlito syrichta50.67e-2190.9
LLPS-Cis-1952Ciona savignyi48.914e-77 248