LLPS-Dar-a316
capza1a
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | F-actin-capping protein subunit alpha |
| Gene Name: | capza1a, capza1 |
| Ensembl Gene: | ENSDARG00000034240.9 |
| Ensembl Protein: | ENSDARP00000123699.1 |
| Organism: | Danio rerio |
| Taxa ID: | 7955 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDART00000149159.2 | ENSDARP00000123699.1 |
| Ensembl | ENSDART00000046973.8 | ENSDARP00000046972.5 |
| UniProt | Q6NWK1, Q6NWK1_DANRE | |
| GeneBank | CU469362, FO904856, BC067561 | , AAH67561.1 |
| Entrez | 327029 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MADFEEQLSD DEKVRIAANF VIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNMD 60 61 QFTPAKLDGS EDQVLITEHG DLGHGRFFDP RKKQSFKFDH LRKEASEAQS YEGEAALRPW 120 121 RDAVDEALRA YVKEHYPSGV CTVYGKTIDG QKTIIACIEG HRFQPQNFWN GRCRSEWKFS 180 181 ISQATAQVVG VLKIQVHYYE DGNVQLVSHK DVQDSLVIST EVQTAKEFVE IIKNAENEYQ 240 241 TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA 286 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGACT TTGAGGAACA GCTTTCCGAC GATGAGAAGG TCCGCATTGC TGCAAATTTT 60 61 GTCATTCATG CGCCCCCTGG AGAGTTTAAT GAAGTCTTCA ATGATGTGCG GCTACTGCTC 120 121 AATAATGACA ATCTGCTCAG GGAAGGGGCG GCTCATGCCT TTGCCCAGTA TAACATGGAT 180 181 CAGTTCACAC CTGCTAAACT TGATGGAAGT GAAGATCAGG TTTTGATCAC AGAGCATGGA 240 241 GATCTTGGCC ACGGCCGATT CTTTGACCCT CGTAAGAAAC AGTCGTTCAA GTTCGACCAC 300 301 CTGAGGAAAG AGGCGAGTGA AGCTCAGTCG TATGAGGGCG AGGCGGCGCT CAGGCCGTGG 360 361 AGAGATGCTG TAGATGAGGC TCTGAGGGCG TACGTTAAAG AACATTACCC CAGCGGAGTC 420 421 TGCACTGTTT ATGGAAAAAC TATAGATGGA CAGAAAACCA TCATTGCCTG TATTGAGGGT 480 481 CATCGATTTC AGCCTCAAAA TTTCTGGAAT GGCCGCTGCC GATCGGAGTG GAAGTTCTCC 540 541 ATTTCTCAGG CCACCGCTCA GGTGGTGGGA GTGCTGAAGA TCCAGGTTCA TTACTATGAG 600 601 GATGGAAACG TGCAGCTGGT CAGCCATAAG GATGTGCAAG ACTCTCTTGT CATCTCTACT 660 661 GAGGTACAGA CTGCCAAGGA GTTTGTCGAG ATCATTAAAA ACGCTGAAAA TGAGTATCAG 720 721 ACGGCCATCA GCGAGAACTA CCAGACCATG TCTGATACCA CCTTCAAGGC CTTACGTCGG 780 781 CAGCTTCCAG TCACCCGCAC CAAGATCGAC TGGAACAAGA TCCTTAGCTA CAAGATCGGC 840 841 AAAGAGATGC AGAACGCTTA G 861 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Actin cortical patch | |
Cellular Component | F-actin capping protein complex | |
Cellular Component | Z disc | |
Molecular Function | Actin filament binding | |
Biological Process | Actin cytoskeleton organization | |
Biological Process | Barbed-end actin filament capping |