LLPS-Dar-3730
usp2a

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ubiquitin-specific peptidase 2a
Gene Name: usp2a
Ensembl Gene: ENSDARG00000020107.10
Ensembl Protein: ENSDARP00000126799.1
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPSMRHSYTV  TIPEEPPATA  LSLLKQDMRR  KNSVSGSMLV  STFVGLLINH  AKNSKSAQGL  60
61    VGLRNLGNTC  FMNSILQCLS  NTQSLRDYCL  HNSHRRDLNN  NNRTHTALME  EFAKLIQTMW  120
121   TSSSSEAVSP  SEFKTQIQRY  APRFVGYNQQ  DAQEFLRFLL  DGLHNEVNRV  TVRPRGNTED  180
181   FDHLPDEEKG  KKMWSKYLER  EDSKIVDLFV  GQLKSSLTCS  ECGYCSTVFD  PFWDLSLPIA  240
241   KGYGEVSLMD  CMRLFTKEDV  LDGDEKPTCY  RCKARRRCTK  KFTVQKFPKI  LVLHLKRFSE  300
301   ARIRTSKLST  FVNFPMKDLD  LREFASDRSS  SAVYNLYAVS  NHSGTTMGGH  YTAYCCNPEN  360
361   GEWYTYNDSR  VTPMSASQVR  SSDAYVLFYE  RAGL  394
Nucleotide CDS Sequence (FASTA)
1     ATGCCAAGCA  TGCGACATTC  ATATACAGTG  ACAATACCAG  AGGAGCCACC  TGCGACTGCG  60
61    CTCTCTCTTC  TCAAACAAGA  CATGAGGAGG  AAAAACTCTG  TGTCCGGCTC  CATGCTGGTC  120
121   TCCACATTCG  TCGGGCTTCT  TATTAATCAT  GCCAAGAACT  CAAAGAGTGC  CCAGGGCCTG  180
181   GTCGGGCTTC  GTAATCTGGG  AAATACATGT  TTTATGAACT  CCATCCTCCA  GTGTCTTAGC  240
241   AACACACAGA  GCCTGCGAGA  CTACTGTCTT  CACAACTCCC  ACCGCCGAGA  CCTCAACAAC  300
301   AACAACCGCA  CACACACTGC  TCTCATGGAA  GAGTTTGCCA  AGCTTATCCA  GACAATGTGG  360
361   ACTTCCTCAA  GCAGTGAAGC  TGTCAGTCCC  TCTGAGTTCA  AAACACAGAT  TCAGAGATAC  420
421   GCCCCCAGAT  TTGTGGGCTA  CAATCAACAG  GATGCTCAGG  AGTTTCTACG  GTTCCTGCTT  480
481   GACGGCTTGC  ACAATGAAGT  AAACAGGGTC  ACGGTCCGGC  CACGGGGAAA  CACAGAAGAT  540
541   TTTGACCACT  TGCCTGATGA  AGAAAAAGGG  AAAAAGATGT  GGTCTAAGTA  TTTAGAGAGA  600
601   GAAGACAGCA  AAATTGTAGA  TCTGTTTGTA  GGCCAGCTAA  AGAGCTCTCT  GACCTGCAGC  660
661   GAATGCGGTT  ATTGTTCCAC  TGTGTTCGAT  CCCTTCTGGG  ATCTTTCCTT  ACCTATCGCC  720
721   AAGGGCTATG  GAGAGGTGAG  CCTAATGGAC  TGCATGCGGC  TCTTTACAAA  AGAAGACGTG  780
781   CTTGATGGGG  ACGAGAAGCC  TACATGTTAC  AGATGCAAAG  CCAGACGGCG  ATGTACGAAG  840
841   AAATTTACGG  TTCAGAAGTT  TCCTAAAATT  TTAGTTCTTC  ATCTGAAACG  CTTCTCAGAA  900
901   GCCCGCATTC  GAACCAGCAA  ACTGTCTACT  TTTGTCAACT  TCCCAATGAA  AGACCTGGAC  960
961   CTCAGGGAAT  TTGCCTCTGA  CAGAAGCAGT  AGTGCTGTGT  ATAATCTGTA  TGCAGTGTCC  1020
1021  AATCACTCAG  GCACGACTAT  GGGAGGCCAC  TACACAGCAT  ACTGCTGCAA  TCCTGAAAAT  1080
1081  GGGGAATGGT  ACACGTATAA  TGACTCCAGA  GTCACGCCAA  TGTCTGCCAG  CCAAGTTCGC  1140
1141  AGTAGCGACG  CCTATGTGCT  GTTCTACGAG  CGAGCTGGAC  TCTGA  1185

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
MIST
Drug
CTD
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-3766Astyanax mexicanus92.820.0 672
LLPS-Xim-3506Xiphophorus maculatus92.440.0 654
LLPS-Orn-3647Oreochromis niloticus92.240.0 649
LLPS-Pof-0919Poecilia formosa91.860.0 648
LLPS-Orl-3050Oryzias latipes90.210.0 600
LLPS-Ten-2383Tetraodon nigroviridis87.50.0 666
LLPS-Lac-2954Latimeria chalumnae86.830.0 609
LLPS-Scf-3698Scleropages formosus86.220.0 673
LLPS-Sah-3224Sarcophilus harrisii82.650.0 570
LLPS-Mod-1500Monodelphis domestica82.650.0 570
LLPS-Aim-0513Ailuropoda melanoleuca81.820.0 568
LLPS-Mup-3886Mustela putorius furo81.820.0 569
LLPS-Caj-2711Callithrix jacchus81.820.0 567
LLPS-Eqc-3112Equus caballus81.820.0 567
LLPS-Fec-3194Felis catus81.820.0 568
LLPS-Leo-3663Lepisosteus oculatus81.770.0 598
LLPS-Ran-3666Rattus norvegicus81.520.0 563
LLPS-Sus-3989Sus scrofa81.520.0 549
LLPS-Caf-2604Canis familiaris81.520.0 565
LLPS-Nol-4508Nomascus leucogenys81.50.0 531
LLPS-Mal-3885Mandrillus leucophaeus81.230.0 566
LLPS-Paa-4615Papio anubis81.230.0 566
LLPS-Cea-2424Cercocebus atys81.230.0 566
LLPS-Maf-1955Macaca fascicularis81.230.0 566
LLPS-Cas-0056Carlito syrichta81.230.0 565
LLPS-Mam-4615Macaca mulatta81.230.0 566
LLPS-Rhb-2754Rhinopithecus bieti81.230.0 566
LLPS-Otg-4692Otolemur garnettii81.230.0 564
LLPS-Man-2967Macaca nemestrina81.230.0 566
LLPS-Bot-0419Bos taurus80.940.0 548
LLPS-Aon-4196Aotus nancymaae80.940.0 560
LLPS-Mum-3951Mus musculus80.940.0 562
LLPS-Tag-3547Taeniopygia guttata80.940.0 576
LLPS-Orc-2897Oryctolagus cuniculus80.940.0 562
LLPS-Hos-1365Homo sapiens80.940.0 563
LLPS-Pat-0726Pan troglodytes80.940.0 564
LLPS-Pap-3354Pan paniscus80.940.0 563
LLPS-Fia-3445Ficedula albicollis80.70.0 578
LLPS-Gog-1169Gorilla gorilla80.650.0 561
LLPS-Gaga-2716Gallus gallus80.650.0 574
LLPS-Ict-2747Ictidomys tridecemlineatus80.640.0 568
LLPS-Loa-1187Loxodonta africana80.520.0 572
LLPS-Fud-3429Fukomys damarensis80.350.0 559
LLPS-Cap-0678Cavia porcellus80.350.0 559
LLPS-Xet-1307Xenopus tropicalis80.170.0 560
LLPS-Anc-2556Anolis carolinensis79.180.0 565
LLPS-Dio-3202Dipodomys ordii78.460.0 586
LLPS-Chs-1042Chlorocebus sabaeus78.210.0 585
LLPS-Icp-0185Ictalurus punctatus75.860.0 587
LLPS-Scm-3167Scophthalmus maximus75.235e-178 506
LLPS-Meg-1308Meleagris gallopavo75.130.0 581
LLPS-Ova-2932Ovis aries74.480.0 574
LLPS-Ora-0748Ornithorhynchus anatinus73.353e-158 456
LLPS-Gaa-3139Gasterosteus aculeatus72.50.0 582
LLPS-Poa-4143Pongo abelii72.439e-163 476
LLPS-Urm-1663Ursus maritimus67.994e-150 444
LLPS-Tar-2645Takifugu rubripes66.330.0 527
LLPS-Cii-2281Ciona intestinalis51.625e-117 351
LLPS-Mea-3579Mesocricetus auratus51.271e-105 330
LLPS-Cis-0575Ciona savignyi50.741e-111 345
LLPS-Drm-0944Drosophila melanogaster47.792e-96 315
LLPS-Myl-2317Myotis lucifugus42.522e-75 258
LLPS-Put-1289Puccinia triticina42.393e-60 217
LLPS-Anp-2069Anas platyrhynchos42.147e-73 251
LLPS-Abg-1073Absidia glauca38.555e-73 251
LLPS-Miv-1501Microbotryum violaceum38.542e-72 251
LLPS-Mel-1506Melampsora laricipopulina38.536e-64 226
LLPS-Tum-1613Tuber melanosporum37.577e-65 228
LLPS-Brn-1110Brassica napus37.391e-58 204
LLPS-Brr-0733Brassica rapa37.394e-58 204
LLPS-Spr-0486Sporisorium reilianum37.295e-69 241
LLPS-Usm-1191Ustilago maydis37.122e-68 239
LLPS-Bro-0132Brassica oleracea36.54e-57 201
LLPS-Crn-0042Cryptococcus neoformans35.444e-65 230
LLPS-Asg-0962Ashbya gossypii35.312e-49 183
LLPS-Pug-1167Puccinia graminis35.094e-51 190
LLPS-Yal-0826Yarrowia lipolytica34.078e-54 197
LLPS-Lem-0841Leptosphaeria maculans32.985e-56 203
LLPS-Asfu-0783Aspergillus fumigatus32.978e-49 183
LLPS-Asni-1337Aspergillus niger32.511e-48 181
LLPS-Nef-1067Neosartorya fischeri30.432e-48 182