LLPS-Dar-3726
kars

▼ OVERVIEW

Status: Unreviewed
Protein Name: Lysine--tRNA ligase; Lysyl-tRNA synthetase
Gene Name: kars
Ensembl Gene: ENSDARG00000103799.3
Ensembl Protein: ENSDARP00000134262.1
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic density, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLTLVRICQL  QALRPRTLAL  PGSQNLPLLI  QGIRWKSDKS  ELKRRMKAEK  KAAEKEAKVK  60
61    EQQEQKETND  KPQQNAYGAD  EETLDPNQYF  KIRSQAIQAL  KGTAEDPYPH  KFHVDLSLTE  120
121   FIERYNHLQP  GDHLTDVVLN  LSGRVHAKRA  SGAKLLFYDL  RGEGVKLQVM  ANSRNYTSEE  180
181   AFVHINNKLR  RGDIIGVRGN  PGKTKKGELS  IIPVEMTLLS  PCLHMLPHLH  FGLKDKETRF  240
241   RQRYLDLILN  DFVRQKFVTR  SKIITYLRSF  LDQLGFLEIE  TPMMNLIPGG  AVAKPFITYH  300
301   NDLNMNLYMR  IAPELYHKML  VVGGIDRVYE  IGRQFRNEGI  DLTHNPEFTT  CEFYMAYADY  360
361   HDLMEITEKL  LSGMVKHITG  AYKVTYHPDG  PEGQAYEIDF  TPPFRRISMT  QELEKELGVK  420
421   FPPPDTYDSD  EMRKFLDDLC  VQKEVECPPP  RTTARLLDKL  VGDFLEVKCI  NPTYICDHPQ  480
481   IMSPLAKWHR  SQKGLTERFE  LFVMKKEICN  AYTELNDPIR  QRELFEQQAK  AKAEGDDEAM  540
541   FIDETFCTAL  EYGLPPTAGW  GMGIDRLTMF  LTDSNNIKEV  LLFPAMKPED  NKPAAPAEGT  600
601   SV  602
Nucleotide CDS Sequence (FASTA)
1     ATGTTGACTC  TGGTCAGAAT  ATGCCAACTG  CAAGCGCTCA  GGCCGCGGAC  GCTTGCTCTT  60
61    CCCGGCTCAC  AAAACCTGCC  TTTGCTTATT  CAAGGAATAC  GCTGGAAAAG  TGACAAAAGT  120
121   GAGCTGAAAA  GGCGCATGAA  AGCTGAGAAG  AAAGCAGCTG  AGAAGGAAGC  CAAGGTCAAA  180
181   GAGCAGCAGG  AACAGAAGGA  GACCAATGAC  AAGCCACAGC  AGAACGCATA  CGGGGCAGAT  240
241   GAGGAAACAC  TGGACCCCAA  TCAATACTTC  AAGATACGTT  CACAAGCCAT  TCAAGCCTTG  300
301   AAGGGAACAG  CCGAAGATCC  TTACCCTCAC  AAATTTCACG  TGGACTTGTC  TCTTACTGAG  360
361   TTCATTGAGC  GCTATAACCA  CCTTCAGCCT  GGAGACCACT  TGACAGATGT  TGTCCTCAAT  420
421   TTATCAGGTC  GTGTTCATGC  TAAGAGGGCT  TCAGGCGCCA  AGCTGCTGTT  CTATGATCTG  480
481   CGAGGAGAAG  GAGTCAAGCT  GCAGGTCATG  GCCAACTCCA  GAAACTACAC  ATCAGAAGAA  540
541   GCGTTTGTGC  ACATCAACAA  CAAACTGAGG  CGTGGAGACA  TCATCGGGGT  CCGGGGGAAC  600
601   CCTGGCAAGA  CAAAGAAGGG  CGAGTTGAGC  ATCATCCCAG  TGGAGATGAC  CCTGCTGTCT  660
661   CCATGTCTTC  ATATGCTTCC  ACATCTTCAC  TTTGGCCTGA  AAGACAAGGA  AACCAGGTTC  720
721   AGACAGCGAT  ATCTGGACCT  GATTCTTAAT  GATTTTGTGA  GACAGAAGTT  TGTTACTCGT  780
781   TCCAAGATTA  TCACGTATCT  CCGCAGCTTT  CTTGACCAGC  TTGGATTTCT  GGAGATTGAA  840
841   ACCCCAATGA  TGAACCTGAT  CCCTGGTGGC  GCAGTAGCAA  AGCCATTTAT  CACCTATCAC  900
901   AATGATCTGA  ACATGAACCT  GTACATGAGA  ATTGCTCCTG  AGCTTTACCA  TAAGATGTTG  960
961   GTAGTTGGAG  GAATCGACCG  CGTGTACGAG  ATTGGCCGTC  AGTTCCGTAA  TGAAGGCATC  1020
1021  GATCTCACTC  ACAACCCAGA  GTTCACCACC  TGTGAGTTCT  ACATGGCCTA  TGCCGACTAT  1080
1081  CACGACCTGA  TGGAAATCAC  AGAGAAGCTT  CTCTCAGGAA  TGGTGAAGCA  CATTACCGGA  1140
1141  GCTTATAAAG  TGACGTATCA  TCCTGATGGT  CCAGAGGGAC  AGGCCTACGA  AATAGACTTC  1200
1201  ACCCCTCCCT  TCAGGCGAAT  CAGCATGACC  CAAGAGCTGG  AGAAGGAGTT  GGGTGTGAAG  1260
1261  TTTCCACCTC  CTGACACCTA  TGACAGTGAC  GAAATGCGCA  AGTTCTTAGA  CGACCTGTGT  1320
1321  GTTCAGAAAG  AAGTTGAATG  TCCTCCTCCC  AGGACAACTG  CTCGACTTCT  TGATAAGTTG  1380
1381  GTGGGAGACT  TCCTGGAGGT  GAAGTGCATC  AACCCAACAT  ACATCTGCGA  TCATCCACAG  1440
1441  ATAATGAGTC  CTCTTGCTAA  ATGGCACAGG  TCACAGAAAG  GTCTAACTGA  ACGTTTTGAA  1500
1501  CTCTTTGTGA  TGAAGAAGGA  GATCTGCAAT  GCCTACACAG  AGTTGAACGA  TCCCATCAGA  1560
1561  CAGCGAGAAC  TGTTTGAGCA  GCAGGCTAAG  GCTAAGGCAG  AAGGTGACGA  CGAGGCCATG  1620
1621  TTCATTGATG  AGACCTTCTG  CACCGCTTTA  GAGTACGGTC  TTCCCCCCAC  AGCAGGATGG  1680
1681  GGAATGGGCA  TCGACCGCCT  CACCATGTTC  CTCACAGACT  CCAACAACAT  CAAGGAGGTG  1740
1741  CTGCTTTTCC  CTGCCATGAA  GCCAGAAGAC  AATAAACCAG  CTGCACCTGC  AGAGGGCACA  1800
1801  TCAGTCTAA  1809

▼ ANNOTATION

Disorder
IUPred2A
Interaction
MIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-0104Oreochromis niloticus90.320.01037
LLPS-Scf-0901Scleropages formosus89.890.01022
LLPS-Leo-0447Lepisosteus oculatus89.080.01043
LLPS-Asm-2177Astyanax mexicanus88.980.01094
LLPS-Icp-0437Ictalurus punctatus87.990.01071
LLPS-Mam-0827Macaca mulatta87.273e-62 207
LLPS-Mum-3957Mus musculus86.120.0 980
LLPS-Caf-1453Canis familiaris85.60.0 968
LLPS-Ran-0288Rattus norvegicus85.360.0 975
LLPS-Hos-0400Homo sapiens85.330.0 966
LLPS-Fud-1216Fukomys damarensis85.330.0 964
LLPS-Fec-0176Felis catus85.220.0 969
LLPS-Sus-0241Sus scrofa85.010.0 971
LLPS-Poa-0708Pongo abelii84.940.0 964
LLPS-Orl-2374Oryzias latipes84.830.01038
LLPS-Aon-0207Aotus nancymaae84.790.0 970
LLPS-Scm-0412Scophthalmus maximus84.590.01032
LLPS-Caj-0631Callithrix jacchus84.510.0 972
LLPS-Mup-1418Mustela putorius furo84.440.0 968
LLPS-Urm-0726Ursus maritimus84.410.0 970
LLPS-Man-2990Macaca nemestrina84.360.0 958
LLPS-Maf-1109Macaca fascicularis84.360.0 958
LLPS-Chs-0942Chlorocebus sabaeus84.360.0 955
LLPS-Mal-4318Mandrillus leucophaeus84.360.0 956
LLPS-Aim-1546Ailuropoda melanoleuca84.220.0 968
LLPS-Xim-0815Xiphophorus maculatus84.210.01033
LLPS-Ict-0843Ictidomys tridecemlineatus84.050.0 972
LLPS-Dio-0667Dipodomys ordii84.030.0 961
LLPS-Pof-0078Poecilia formosa83.720.01038
LLPS-Gaa-1719Gasterosteus aculeatus83.520.01025
LLPS-Myl-1908Myotis lucifugus83.430.0 960
LLPS-Tut-0669Tursiops truncatus83.40.0 962
LLPS-Anp-2493Anas platyrhynchos83.370.0 910
LLPS-Cas-1142Carlito syrichta83.270.0 982
LLPS-Lac-2951Latimeria chalumnae83.160.0 972
LLPS-Gaga-2768Gallus gallus83.150.0 955
LLPS-Pat-1151Pan troglodytes83.140.0 937
LLPS-Gog-1873Gorilla gorilla83.140.0 937
LLPS-Pap-0912Pan paniscus82.950.0 933
LLPS-Nol-1864Nomascus leucogenys82.950.0 934
LLPS-Tag-2307Taeniopygia guttata82.540.0 945
LLPS-Mod-3433Monodelphis domestica82.490.0 925
LLPS-Anc-0523Anolis carolinensis81.820.0 925
LLPS-Cap-0299Cavia porcellus81.420.0 971
LLPS-Tar-1233Takifugu rubripes81.350.0 990
LLPS-Eqc-1290Equus caballus81.110.0 970
LLPS-Fia-1845Ficedula albicollis80.740.0 954
LLPS-Ora-0635Ornithorhynchus anatinus80.440.0 962
LLPS-Ova-1793Ovis aries80.180.0 900
LLPS-Cea-1603Cercocebus atys79.620.0 960
LLPS-Paa-0011Papio anubis79.620.0 960
LLPS-Meg-1811Meleagris gallopavo79.30.0 926
LLPS-Rhb-2042Rhinopithecus bieti79.270.0 955
LLPS-Bot-1847Bos taurus78.590.0 976
LLPS-Loa-1972Loxodonta africana78.380.0 965
LLPS-Otg-0034Otolemur garnettii77.990.0 883
LLPS-Sah-1010Sarcophilus harrisii77.680.0 875
LLPS-Orc-0066Oryctolagus cuniculus75.310.0 865
LLPS-Pes-0155Pelodiscus sinensis74.570.0 834
LLPS-Cis-0586Ciona savignyi71.570.0 817
LLPS-Drm-0604Drosophila melanogaster71.460.0 810
LLPS-Coc-0219Corchorus capsularis70.920.0 555
LLPS-Cii-0143Ciona intestinalis69.740.0 810
LLPS-Chr-0632Chlamydomonas reinhardtii65.490.0 733
LLPS-Abg-0068Absidia glauca64.50.0 716
LLPS-Cae-0047Caenorhabditis elegans63.710.0 705
LLPS-Scc-0057Schizosaccharomyces cryophilus62.980.0 695
LLPS-Vir-1103Vigna radiata62.970.0 616
LLPS-Scp-0894Schizosaccharomyces pombe62.140.0 664
LLPS-Pot-1986Populus trichocarpa61.870.0 685
LLPS-Scj-0570Schizosaccharomyces japonicus61.750.0 662
LLPS-Osl-0393Ostreococcus lucimarinus61.570.0 667
LLPS-Mae-0978Manihot esculenta61.510.0 698
LLPS-Gas-0304Galdieria sulphuraria60.920.0 672
LLPS-Viv-1446Vitis vinifera60.790.0 709
LLPS-Glm-2386Glycine max60.670.0 677
LLPS-Gor-0901Gossypium raimondii60.620.0 701
LLPS-Usm-0852Ustilago maydis60.540.0 650
LLPS-Kop-0288Komagataella pastoris60.310.0 650
LLPS-Hov-0505Hordeum vulgare60.310.0 647
LLPS-Ors-1160Oryza sativa60.290.0 687
LLPS-Org-0459Oryza glaberrima60.290.0 687
LLPS-Sot-0094Solanum tuberosum60.290.0 673
LLPS-Miv-0674Microbotryum violaceum60.270.0 655
LLPS-Orbr-1126Oryza brachyantha60.260.0 688
LLPS-Cus-0591Cucumis sativus60.250.0 704
LLPS-Nia-1370Nicotiana attenuata60.110.0 679
LLPS-Orm-0052Oryza meridionalis60.110.0 667
LLPS-Sob-0411Sorghum bicolor60.080.0 669
LLPS-Spr-0874Sporisorium reilianum60.080.0 647
LLPS-Brd-0277Brachypodium distachyon60.070.0 682
LLPS-Asg-1214Ashbya gossypii60.040.0 645
LLPS-Sac-0519Saccharomyces cerevisiae60.040.0 649
LLPS-Tru-0589Triticum urartu60.00.0 654
LLPS-Met-0219Medicago truncatula59.890.0 667
LLPS-Tum-1163Tuber melanosporum59.880.0 627
LLPS-Zem-2251Zea mays59.810.0 649
LLPS-Via-1295Vigna angularis59.810.0 667
LLPS-Sei-0481Setaria italica59.690.0 653
LLPS-Phv-1264Phaseolus vulgaris59.630.0 667
LLPS-Yal-0946Yarrowia lipolytica59.620.0 652
LLPS-Brr-1451Brassica rapa59.590.0 675
LLPS-Php-0021Physcomitrella patens59.450.0 663
LLPS-Ori-0297Oryza indica59.40.0 664
LLPS-Thc-1235Theobroma cacao59.360.0 669
LLPS-Bro-1498Brassica oleracea59.340.0 681
LLPS-Asni-0425Aspergillus niger59.250.0 652
LLPS-Brn-2178Brassica napus59.160.0 678
LLPS-Amt-0023Amborella trichopoda59.130.0 686
LLPS-Lem-0504Leptosphaeria maculans59.120.0 528
LLPS-Lep-0203Leersia perrieri59.040.0 657
LLPS-Hea-1890Helianthus annuus58.990.0 685
LLPS-Mua-0189Musa acuminata58.950.0 682
LLPS-Tra-2089Triticum aestivum58.890.0 660
LLPS-Dac-0182Daucus carota58.870.0 674
LLPS-Orp-2030Oryza punctata58.740.0 655
LLPS-Nef-0178Neosartorya fischeri58.650.0 655
LLPS-Art-0103Arabidopsis thaliana58.530.0 664
LLPS-Blg-0152Blumeria graminis58.460.0 631
LLPS-Arl-1613Arabidopsis lyrata58.260.0 669
LLPS-Aso-0303Aspergillus oryzae58.220.0 653
LLPS-Asf-0205Aspergillus flavus58.220.0 653
LLPS-Orgl-0362Oryza glumaepatula58.170.0 630
LLPS-Asn-0676Aspergillus nidulans58.030.0 646
LLPS-Orr-0505Oryza rufipogon57.980.0 628
LLPS-Asc-0974Aspergillus clavatus57.890.0 651
LLPS-Orb-1605Oryza barthii57.790.0 628
LLPS-Orni-0328Oryza nivara57.790.0 627
LLPS-Sol-0793Solanum lycopersicum57.770.0 659
LLPS-Put-0953Puccinia triticina57.640.0 636
LLPS-Asfu-0707Aspergillus fumigatus57.590.0 652
LLPS-Fuo-0284Fusarium oxysporum57.280.0 616
LLPS-Fus-0870Fusarium solani57.20.0 623
LLPS-Prp-0336Prunus persica57.040.0 648
LLPS-Trr-0437Trichoderma reesei56.660.0 613
LLPS-Crn-0179Cryptococcus neoformans56.50.0 608
LLPS-Pytr-0130Pyrenophora triticirepentis56.490.0 608
LLPS-Fuv-0052Fusarium verticillioides56.420.0 615
LLPS-Pyt-0451Pyrenophora teres56.110.0 604
LLPS-Ast-0614Aspergillus terreus56.060.0 651
LLPS-Cogr-0800Colletotrichum graminicola56.010.0 627
LLPS-Mel-0244Melampsora laricipopulina56.010.0 620
LLPS-Trv-0062Trichoderma virens55.860.0 613
LLPS-Cym-0187Cyanidioschyzon merolae55.790.0 625
LLPS-Cog-0289Colletotrichum gloeosporioides55.680.0 614
LLPS-Scs-0299Sclerotinia sclerotiorum55.450.0 612
LLPS-Pug-0910Puccinia graminis54.963e-169 501
LLPS-Beb-0003Beauveria bassiana54.940.0 584
LLPS-Coo-1327Colletotrichum orbiculare53.640.0 589
LLPS-Phn-0471Phaeosphaeria nodorum53.250.0 605
LLPS-Dos-0176Dothistroma septosporum53.240.0 572
LLPS-Zyt-0636Zymoseptoria tritici52.190.0 565
LLPS-Map-0915Magnaporthe poae51.970.0 563
LLPS-Gag-0862Gaeumannomyces graminis51.410.0 557
LLPS-Sem-0173Selaginella moellendorffii51.120.0 551
LLPS-Nec-0388Neurospora crassa50.280.0 563
LLPS-Mao-0004Magnaporthe oryzae50.180.0 555
LLPS-Ved-1100Verticillium dahliae48.82e-170 505
LLPS-Chc-0464Chondrus crispus40.162e-122 380