LLPS-Dar-3602
otud6b

▼ OVERVIEW

Status: Unreviewed
Protein Name: Deubiquitinase OTUD6B
Gene Name: otud6b, zgc:56305
Ensembl Gene: ENSDARG00000102705.2
Ensembl Protein: ENSDARP00000130662.1
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of different cellular processes.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEEVETAEEQ  LAKQHRKEKK  DLQAKIQSMK  NAVPKNDKKR  RKQLTEDIAK  LEAELSQKHE  60
61    NELKLQNTSS  VEEVSVALDS  MSVANHEEQS  DPSKQSRTSK  AQKRRDKKAA  LEKEREMRIA  120
121   EAEVENLSGS  RHQEGLKLRE  KLVERHLQIK  EISSDGHCMY  RAVEHQLTER  GLALGLKELR  180
181   DQTAQYMRSH  ADDFMPFLTN  PNTGDMYTAE  EFEKYCTDVA  DTAAWGGQLE  LKALSQVLQL  240
241   PLEVIQADSP  CITIGEEYDK  PKITLIYMRH  AYGLGEHYNS  VEPLKDLANE  EEG  293
Nucleotide CDS Sequence (FASTA)
1     Sequence u  navailable  20

▼ KEYWORD

ID
Family
Complete proteome
Hydrolase
Protease
Reference proteome
Thiol protease
Ubl conjugation pathway

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Thiol-dependent ubiquitin-specific protease activity
Molecular Function
Thiol-dependent ubiquitinyl hydrolase activity
Biological Process
Protein deubiquitination

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Interaction
MIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-1318Astyanax mexicanus78.456e-165 467
LLPS-Leo-1459Lepisosteus oculatus72.541e-148 426
LLPS-Ora-1611Ornithorhynchus anatinus69.887e-37 134
LLPS-Ten-0958Tetraodon nigroviridis69.761e-140 406
LLPS-Orn-1631Oreochromis niloticus69.571e-144 416
LLPS-Pof-2935Poecilia formosa69.442e-142 410
LLPS-Scf-2680Scleropages formosus69.366e-143 411
LLPS-Xim-1388Xiphophorus maculatus69.134e-136 394
LLPS-Scm-2731Scophthalmus maximus68.775e-141 407
LLPS-Gaa-1788Gasterosteus aculeatus68.42e-135 392
LLPS-Orl-1952Oryzias latipes67.893e-139 402
LLPS-Tar-0144Takifugu rubripes67.472e-136 395
LLPS-Icp-0871Ictalurus punctatus66.679e-138 399
LLPS-Aim-0639Ailuropoda melanoleuca65.614e-118 349
LLPS-Urm-3045Ursus maritimus65.373e-118 350
LLPS-Mod-3399Monodelphis domestica65.021e-116 345
LLPS-Caj-3531Callithrix jacchus64.662e-119 353
LLPS-Sah-1777Sarcophilus harrisii64.661e-117 347
LLPS-Cap-0882Cavia porcellus64.662e-117 348
LLPS-Otg-3471Otolemur garnettii64.417e-116 342
LLPS-Bot-3063Bos taurus64.392e-115 341
LLPS-Ict-0112Ictidomys tridecemlineatus64.111e-118 350
LLPS-Anp-1861Anas platyrhynchos64.083e-115 342
LLPS-Sus-3492Sus scrofa64.065e-115 340
LLPS-Ran-1459Rattus norvegicus64.035e-113 335
LLPS-Fia-0411Ficedula albicollis64.021e-106 318
LLPS-Tag-0789Taeniopygia guttata63.961e-114 340
LLPS-Mup-1204Mustela putorius furo63.768e-118 348
LLPS-Gog-3407Gorilla gorilla63.762e-119 353
LLPS-Loa-0930Loxodonta africana63.763e-117 346
LLPS-Eqc-1029Equus caballus63.736e-115 340
LLPS-Aon-1342Aotus nancymaae63.447e-116 344
LLPS-Tut-0074Tursiops truncatus63.414e-115 342
LLPS-Chs-3517Chlorocebus sabaeus63.419e-118 347
LLPS-Maf-0883Macaca fascicularis63.415e-117 347
LLPS-Poa-1316Pongo abelii63.413e-118 350
LLPS-Rhb-0288Rhinopithecus bieti63.415e-118 349
LLPS-Fec-1042Felis catus63.254e-115 341
LLPS-Xet-3361Xenopus tropicalis63.235e-123 361
LLPS-Pes-0206Pelodiscus sinensis63.21e-109 326
LLPS-Pat-0793Pan troglodytes63.123e-115 342
LLPS-Pap-0874Pan paniscus63.123e-115 342
LLPS-Cas-2209Carlito syrichta63.091e-118 349
LLPS-Ova-2622Ovis aries63.072e-116 344
LLPS-Paa-3483Papio anubis63.072e-116 345
LLPS-Mal-1229Mandrillus leucophaeus63.072e-116 345
LLPS-Fud-1228Fukomys damarensis63.072e-116 345
LLPS-Orc-2732Oryctolagus cuniculus62.967e-118 348
LLPS-Nol-3117Nomascus leucogenys62.853e-118 350
LLPS-Ere-0240Erinaceus europaeus62.772e-112 334
LLPS-Mea-0300Mesocricetus auratus62.774e-111 332
LLPS-Hos-3175Homo sapiens62.779e-115 341
LLPS-Dio-2937Dipodomys ordii62.722e-116 344
LLPS-Gaga-2804Gallus gallus62.682e-113 337
LLPS-Myl-3277Myotis lucifugus62.545e-122 358
LLPS-Caf-0711Canis familiaris62.412e-113 340
LLPS-Mum-3715Mus musculus62.192e-113 337
LLPS-Meg-0504Meleagris gallopavo61.731e-108 325
LLPS-Lac-2912Latimeria chalumnae60.092e-69 221
LLPS-Anc-2803Anolis carolinensis56.98e-97 295
LLPS-Chr-1403Chlamydomonas reinhardtii45.929e-38 143
LLPS-Abg-0160Absidia glauca45.381e-29 117
LLPS-Cii-2128Ciona intestinalis44.28e-71 227
LLPS-Cis-1579Ciona savignyi44.017e-68 219
LLPS-Sem-1533Selaginella moellendorffii43.013e-38 140
LLPS-Orgl-0195Oryza glumaepatula42.34e-51 177
LLPS-Orni-1945Oryza nivara42.34e-51 177
LLPS-Org-2092Oryza glaberrima42.34e-51 177
LLPS-Ors-0780Oryza sativa42.33e-51 177
LLPS-Sei-0702Setaria italica42.246e-53 182
LLPS-Lep-1844Leersia perrieri42.162e-50 175
LLPS-Tru-0481Triticum urartu42.023e-47 167
LLPS-Ori-1082Oryza indica41.884e-51 177
LLPS-Orr-0574Oryza rufipogon41.884e-51 177
LLPS-Orbr-1731Oryza brachyantha41.888e-51 176
LLPS-Orb-1135Oryza barthii41.836e-49 170
LLPS-Brd-1467Brachypodium distachyon41.812e-50 176
LLPS-Tra-0877Triticum aestivum41.783e-50 175
LLPS-Orp-1843Oryza punctata41.781e-50 176
LLPS-Osl-0036Ostreococcus lucimarinus41.616e-31 123
LLPS-Drm-0339Drosophila melanogaster41.532e-59 199
LLPS-Miv-0673Microbotryum violaceum41.53e-27 114
LLPS-Orm-1431Oryza meridionalis41.411e-48 170
LLPS-Hov-0028Hordeum vulgare41.251e-49 173
LLPS-Nia-2504Nicotiana attenuata40.981e-45 162
LLPS-Sob-0069Sorghum bicolor40.981e-46 166
LLPS-Prp-0346Prunus persica40.728e-48 168
LLPS-Art-0653Arabidopsis thaliana40.394e-48 169
LLPS-Dac-0806Daucus carota40.195e-53 182
LLPS-Zem-0569Zea mays40.03e-45 162
LLPS-Gor-1652Gossypium raimondii39.473e-46 164
LLPS-Coc-1034Corchorus capsularis39.468e-48 167
LLPS-Brn-2588Brassica napus39.246e-46 163
LLPS-Arl-0192Arabidopsis lyrata39.167e-51 176
LLPS-Bro-2501Brassica oleracea39.057e-48 168
LLPS-Php-0059Physcomitrella patens38.982e-39 146
LLPS-Glm-0561Glycine max38.945e-47 166
LLPS-Sot-1369Solanum tuberosum38.916e-45 161
LLPS-Vir-0642Vigna radiata38.782e-44 160
LLPS-Cae-1536Caenorhabditis elegans38.753e-32 127
LLPS-Via-1731Vigna angularis38.566e-48 169
LLPS-Thc-0606Theobroma cacao38.564e-45 161
LLPS-Hea-1082Helianthus annuus38.461e-45 162
LLPS-Chc-1106Chondrus crispus38.379e-33 128
LLPS-Phv-1817Phaseolus vulgaris38.314e-49 172
LLPS-Met-1337Medicago truncatula38.242e-49 172
LLPS-Mae-1231Manihot esculenta38.194e-45 161
LLPS-Amt-0765Amborella trichopoda38.086e-48 169
LLPS-Pot-0783Populus trichocarpa37.911e-47 168
LLPS-Mel-0291Melampsora laricipopulina37.756e-28 114
LLPS-Brr-1284Brassica rapa37.628e-44 157
LLPS-Mua-0542Musa acuminata37.586e-39 145
LLPS-Viv-0274Vitis vinifera37.384e-44 159
LLPS-Gas-0896Galdieria sulphuraria37.171e-1578.2
LLPS-Cus-2109Cucumis sativus36.964e-49 172
LLPS-Sol-1538Solanum lycopersicum36.741e-43 157
LLPS-Spr-0373Sporisorium reilianum36.072e-27 114
LLPS-Usm-1252Ustilago maydis35.11e-26 112
LLPS-Crn-1115Cryptococcus neoformans34.972e-25 107
LLPS-Scj-0400Schizosaccharomyces japonicus34.884e-43 155
LLPS-Fus-1379Fusarium solani33.883e-30 121
LLPS-Fuv-1355Fusarium verticillioides33.669e-30 119
LLPS-Trv-0676Trichoderma virens33.332e-30 121
LLPS-Mao-0541Magnaporthe oryzae32.82e-28 116
LLPS-Put-0026Puccinia triticina32.435e-25 107
LLPS-Zyt-1150Zymoseptoria tritici32.381e-32 127
LLPS-Cog-0684Colletotrichum gloeosporioides32.195e-28 115
LLPS-Dos-0523Dothistroma septosporum31.727e-30 120
LLPS-Fuo-1188Fusarium oxysporum31.615e-27 112
LLPS-Scc-0983Schizosaccharomyces cryophilus31.427e-33 128
LLPS-Cogr-0551Colletotrichum graminicola31.414e-28 115
LLPS-Coo-1332Colletotrichum orbiculare31.256e-29 117
LLPS-Scs-0638Sclerotinia sclerotiorum31.072e-35 135
LLPS-Blg-0446Blumeria graminis30.941e-27 114
LLPS-Asni-0288Aspergillus niger30.529e-29 117
LLPS-Asfu-0885Aspergillus fumigatus30.381e-27 114
LLPS-Asf-0855Aspergillus flavus30.364e-27 112
LLPS-Lem-0651Leptosphaeria maculans30.061e-1476.6
LLPS-Pug-0953Puccinia graminis30.041e-25 109
LLPS-Trr-0731Trichoderma reesei29.846e-23 100
LLPS-Nef-0523Neosartorya fischeri29.797e-28 114
LLPS-Kop-0220Komagataella pastoris29.731e-26 111
LLPS-Aso-1084Aspergillus oryzae29.73e-23 101
LLPS-Phn-0214Phaeosphaeria nodorum29.624e-25 106
LLPS-Tum-0552Tuber melanosporum29.583e-23 101
LLPS-Beb-0349Beauveria bassiana29.362e-24 104
LLPS-Sac-0458Saccharomyces cerevisiae29.286e-31 123
LLPS-Ved-0215Verticillium dahliae29.231e-23 102
LLPS-Asn-1319Aspergillus nidulans29.021e-24 105
LLPS-Nec-1112Neurospora crassa28.793e-23 101
LLPS-Gag-1006Gaeumannomyces graminis28.781e-24 105
LLPS-Scp-0727Schizosaccharomyces pombe28.621e-31 125
LLPS-Ast-0271Aspergillus terreus28.363e-26 110
LLPS-Yal-1153Yarrowia lipolytica28.254e-30 120
LLPS-Asc-0305Aspergillus clavatus28.021e-24 105
LLPS-Pytr-1154Pyrenophora triticirepentis27.714e-2297.8
LLPS-Pyt-1327Pyrenophora teres27.692e-2093.6
LLPS-Asg-0671Ashbya gossypii26.239e-2091.3