DrLLPS - Data resource of LLPS

LLPS-Dar-3387
isg20

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Interferon-stimulated exonuclease gene
Gene Name:	isg20
Ensembl Gene:	ENSDARG00000079783.5
Ensembl Protein:	ENSDARP00000128266.1
Organism:	Danio rerio
Taxa ID:	7955
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-2879	Q8WTP8	Client	Nucleolus	53.43	1e-147	435

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSDART00000154066.2	ENSDARP00000128266.1
UniProt		E7F5Q4, E7F5Q4_DANRE
GeneBank	BX294110
RefSeq	XM_003201436.4, XM_017354243.1	XP_003201484.1, XP_017209732.1
Entrez	100534720

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSTLLWKHLN SNGVEQNIHT PASVKETSSI SHQKKKCKRK KNIKKKNPAI HDTSFEQNRG 60 61 QKRKLLDNKT ECIKNGSTSD FVSEESNNMQ FKRPRITHHT LPGESWEVDS GFSSESSPPT 120 121 SGRSSPCLRI DHSRIVAMDC EMVGTGPGGR RSEVARCSIV DYYGNVVYDS YILPQDPVTD 180 181 YRTRWSGIRS HHLRQAVPFE HAQNEILKIL KGKIIVGHAL YHDLNVLYIS VQPHMIRDTC 240 241 SCVLLRQLYD ANQNCNISLK KLAQKLLNRT IQVDRQGHCS VEDALSALDL YKLVEDQWEN 300 301 NILCQDSNAE LSQQFSNNSL KHYLQDQYWP ENMMDCSL 338
Nucleotide CDS Sequence (FASTA)
1 ATGTCTACTT TACTCTGGAA ACACCTCAAC AGCAATGGTG TGGAGCAAAA TATTCACACG 60 61 CCAGCCTCTG TCAAAGAAAC ATCCTCTATT TCCCATCAGA AAAAAAAATG TAAACGAAAG 120 121 AAAAATATTA AAAAGAAGAA TCCCGCAATC CATGATACAT CCTTTGAGCA GAATAGAGGA 180 181 CAGAAACGAA AGCTTCTGGA CAACAAGACG GAGTGTATTA AAAATGGAAG TACATCAGAT 240 241 TTTGTATCTG AAGAGTCAAA TAATATGCAG TTCAAAAGGC CTAGAATAAC CCATCATACA 300 301 CTGCCTGGAG AATCATGGGA AGTGGATAGT GGATTTTCTT CTGAAAGTAG TCCGCCCACT 360 361 AGTGGCAGGA GTTCGCCATG TTTAAGAATA GATCACTCCA GGATTGTAGC AATGGACTGT 420 421 GAAATGGTCG GCACTGGACC TGGAGGTCGG CGTAGTGAAG TGGCACGCTG TAGTATTGTT 480 481 GATTATTATG GTAATGTAGT GTATGATAGT TATATTTTAC CTCAGGATCC AGTCACTGAC 540 541 TATCGCACAA GATGGAGCGG CATTAGAAGC CATCATTTAA GACAAGCGGT GCCTTTTGAG 600 601 CATGCTCAGA ATGAGATTCT CAAGATCCTC AAAGGGAAGA TTATTGTTGG CCATGCCTTA 660 661 TATCATGACT TAAATGTTCT CTACATCTCT GTCCAGCCAC ATATGATCAG AGATACCTGC 720 721 TCTTGTGTCC TGCTGCGACA GCTGTATGAT GCTAACCAGA ATTGTAACAT CTCTCTGAAG 780 781 AAGCTGGCAC AGAAGCTTCT CAATAGGACC ATACAGGTTG ACAGACAGGG ACATTGTTCT 840 841 GTTGAAGATG CTCTTTCTGC TCTAGACCTG TACAAACTGG TGGAGGACCA GTGGGAGAAC 900 901 AACATCCTGT GCCAGGATTC AAACGCTGAA CTATCCCAAC AGTTTTCCAA CAACTCCCTC 960 961 AAACACTATT TACAGGACCA GTACTGGCCA GAAAATATGA TGGACTGCAG CCTGTAA 1017

▼ ANNOTATION

Disorder
IUPred2A

Domain
SMART	CDD	Gene3D

Interaction
MIST

Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Urm-1026	Ursus maritimus	65.71	2e-29	113
LLPS-Asm-0603	Astyanax mexicanus	59.41	9e-85	268
LLPS-Icp-2052	Ictalurus punctatus	59.4	5e-71	231
LLPS-Tar-3528	Takifugu rubripes	58.8	3e-72	234
LLPS-Orl-1456	Oryzias latipes	58.49	9e-53	179
LLPS-Orn-3774	Oreochromis niloticus	57.69	1e-71	233
LLPS-Xet-1713	Xenopus tropicalis	56.91	6e-55	186
LLPS-Leo-2992	Lepisosteus oculatus	56.74	1e-66	215
LLPS-Gaa-2149	Gasterosteus aculeatus	56.2	3e-70	228
LLPS-Gaga-2143	Gallus gallus	55.56	3e-55	189
LLPS-Pof-3420	Poecilia formosa	54.95	2e-59	201
LLPS-Loa-0501	Loxodonta africana	54.44	1e-49	175
LLPS-Otg-2000	Otolemur garnettii	54.44	3e-49	174
LLPS-Aim-0011	Ailuropoda melanoleuca	53.85	1e-49	175
LLPS-Lac-1922	Latimeria chalumnae	53.85	3e-52	182
LLPS-Bot-0025	Bos taurus	53.53	5e-49	174
LLPS-Ova-0005	Ovis aries	53.53	5e-49	174
LLPS-Pes-1076	Pelodiscus sinensis	53.53	9e-51	177
LLPS-Myl-0034	Myotis lucifugus	53.45	6e-48	171
LLPS-Mup-1024	Mustela putorius furo	53.25	1e-48	172
LLPS-Gog-1621	Gorilla gorilla	53.25	9e-48	171
LLPS-Caf-0897	Canis familiaris	53.25	1e-48	172
LLPS-Poa-2573	Pongo abelii	53.25	6e-48	171
LLPS-Nol-1564	Nomascus leucogenys	53.25	8e-48	171
LLPS-Pap-2382	Pan paniscus	53.25	8e-48	171
LLPS-Pat-3275	Pan troglodytes	53.25	9e-48	170
LLPS-Hos-0641	Homo sapiens	53.25	9e-48	170
LLPS-Sus-2249	Sus scrofa	53.22	1e-49	175
LLPS-Anc-0992	Anolis carolinensis	52.94	7e-52	181
LLPS-Orc-0076	Oryctolagus cuniculus	52.94	2e-49	174
LLPS-Xim-1369	Xiphophorus maculatus	52.79	8e-58	196
LLPS-Scf-1755	Scleropages formosus	52.66	3e-46	167
LLPS-Rhb-2629	Rhinopithecus bieti	52.66	8e-48	170
LLPS-Meg-2226	Meleagris gallopavo	52.63	4e-51	174
LLPS-Caj-1115	Callithrix jacchus	52.35	1e-42	156
LLPS-Cas-0018	Carlito syrichta	52.35	1e-49	175
LLPS-Fec-0813	Felis catus	52.35	4e-48	171
LLPS-Ten-2558	Tetraodon nigroviridis	52.33	5e-59	195
LLPS-Cap-0556	Cavia porcellus	52.3	3e-48	172
LLPS-Eqc-2863	Equus caballus	52.0	2e-48	172
LLPS-Paa-3076	Papio anubis	51.96	5e-48	171
LLPS-Mal-0339	Mandrillus leucophaeus	51.96	5e-48	171
LLPS-Cea-1779	Cercocebus atys	51.96	5e-48	171
LLPS-Sah-2556	Sarcophilus harrisii	51.96	1e-56	193
LLPS-Maf-3042	Macaca fascicularis	51.96	4e-48	171
LLPS-Chs-0535	Chlorocebus sabaeus	51.96	4e-48	171
LLPS-Mam-2249	Macaca mulatta	51.96	4e-48	171
LLPS-Man-1112	Macaca nemestrina	51.96	5e-48	171
LLPS-Aon-1061	Aotus nancymaae	51.76	7e-43	157
LLPS-Ict-2375	Ictidomys tridecemlineatus	51.72	2e-45	164
LLPS-Mum-0297	Mus musculus	51.48	2e-46	167
LLPS-Fud-0948	Fukomys damarensis	51.46	1e-49	176
LLPS-Mod-0176	Monodelphis domestica	51.18	2e-45	163
LLPS-Ran-0148	Rattus norvegicus	50.84	1e-46	167
LLPS-Dio-0046	Dipodomys ordii	50.59	8e-45	162
LLPS-Scm-0707	Scophthalmus maximus	50.34	1e-67	223
LLPS-Mea-3039	Mesocricetus auratus	49.69	6e-33	126
LLPS-Tag-3385	Taeniopygia guttata	49.28	4e-57	194
LLPS-Tut-0876	Tursiops truncatus	48.21	1e-48	172
LLPS-Ere-0776	Erinaceus europaeus	47.96	4e-47	166
LLPS-Fia-3296	Ficedula albicollis	47.37	1e-53	186
LLPS-Asg-0576	Ashbya gossypii	46.88	7e-36	137
LLPS-Put-0503	Puccinia triticina	46.21	9e-31	119
LLPS-Pug-1274	Puccinia graminis	45.83	2e-38	142
LLPS-Scc-0650	Schizosaccharomyces cryophilus	44.91	2e-34	132
LLPS-Scj-0174	Schizosaccharomyces japonicus	44.71	1e-33	130
LLPS-Pytr-0585	Pyrenophora triticirepentis	44.57	6e-29	119
LLPS-Scp-1154	Schizosaccharomyces pombe	44.31	7e-32	125
LLPS-Cym-0703	Cyanidioschyzon merolae	44.25	8e-29	119
LLPS-Phn-1166	Phaeosphaeria nodorum	43.72	4e-30	122
LLPS-Gas-0610	Galdieria sulphuraria	43.53	4e-32	127
LLPS-Lem-0026	Leptosphaeria maculans	43.01	7e-28	116
LLPS-Ora-0453	Ornithorhynchus anatinus	42.94	3e-31	126
LLPS-Pyt-1269	Pyrenophora teres	42.93	1e-28	118
LLPS-Sac-0150	Saccharomyces cerevisiae	42.77	2e-34	133
LLPS-Cogr-1213	Colletotrichum graminicola	42.33	1e-28	118
LLPS-Cae-1255	Caenorhabditis elegans	41.95	2e-36	138
LLPS-Abg-1074	Absidia glauca	41.92	7e-31	124
LLPS-Cii-1662	Ciona intestinalis	41.92	7e-29	117
LLPS-Trv-0215	Trichoderma virens	41.88	2e-28	117
LLPS-Cog-1210	Colletotrichum gloeosporioides	41.72	2e-29	120
LLPS-Spr-1251	Sporisorium reilianum	41.46	2e-30	123
LLPS-Trr-0826	Trichoderma reesei	41.25	4e-28	116
LLPS-Orbr-1016	Oryza brachyantha	41.18	4e-30	121
LLPS-Fuv-0227	Fusarium verticillioides	41.1	6e-29	118
LLPS-Phv-0655	Phaseolus vulgaris	40.94	1e-27	114
LLPS-Tra-0548	Triticum aestivum	40.83	3e-34	132
LLPS-Orgl-0378	Oryza glumaepatula	40.59	3e-30	121
LLPS-Orb-0149	Oryza barthii	40.59	3e-29	121
LLPS-Orni-1155	Oryza nivara	40.59	2e-29	120
LLPS-Orm-1696	Oryza meridionalis	40.59	1e-30	122
LLPS-Orr-0668	Oryza rufipogon	40.59	3e-29	120
LLPS-Org-0458	Oryza glaberrima	40.59	4e-30	121
LLPS-Ors-1329	Oryza sativa	40.59	3e-30	121
LLPS-Lep-1088	Leersia perrieri	40.46	2e-30	122
LLPS-Sei-1087	Setaria italica	40.46	1e-29	120
LLPS-Orp-0700	Oryza punctata	40.46	2e-30	122
LLPS-Sob-1251	Sorghum bicolor	40.46	9e-31	123
LLPS-Brd-2337	Brachypodium distachyon	40.24	5e-31	124
LLPS-Mua-0966	Musa acuminata	40.12	2e-28	115
LLPS-Viv-0824	Vitis vinifera	40.12	4e-31	124
LLPS-Sem-1527	Selaginella moellendorffii	40.0	1e-29	117
LLPS-Amt-1051	Amborella trichopoda	40.0	1e-27	113
LLPS-Zem-1140	Zea mays	39.88	3e-29	119
LLPS-Ved-0908	Verticillium dahliae	39.88	1e-27	114
LLPS-Hov-1010	Hordeum vulgare	39.64	5e-33	130
LLPS-Php-2270	Physcomitrella patens	39.57	2e-31	125
LLPS-Usm-1213	Ustilago maydis	39.55	4e-31	125
LLPS-Coo-0259	Colletotrichum orbiculare	39.26	1e-27	115
LLPS-Crn-0046	Cryptococcus neoformans	38.82	3e-28	117
LLPS-Sot-0079	Solanum tuberosum	38.46	6e-28	115
LLPS-Sol-1375	Solanum lycopersicum	38.46	5e-28	115
LLPS-Cus-0069	Cucumis sativus	38.32	9e-28	114

LLPS-Dar-3387isg20

Protein Sequence

Nucleotide Sequence

LLPS-Dar-3387
isg20