LLPS-Dar-3260
cdk5

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cyclin-dependent kinase 5
Gene Name: cdk5
Ensembl Gene: ENSDARG00000056683.8
Ensembl Protein: ENSDARP00000073666.3
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MQKYEKLEKI  GEGTYGTVFK  AKNRETHEIV  ALKRVRLDDD  DEGVPSSALR  EICLLKELKH  60
61    KNIVRLHDVL  HSDKKLTLVF  EYCDQDLKKY  FDSCNGDLDP  EIVKSFMYQL  LKGLAFCHSR  120
121   NVLHRDLKPQ  NLLINRNGEL  KLADFGLARA  FGIPVRCYSA  EVVTLWYRPP  DVLFGAKLYS  180
181   TSIDMWSAGC  IFAELANAGR  PLFPGNDVDD  QLKRIFRLLG  TPTEEQWQTM  NKLPDYKPYP  240
241   MYPATTSLVN  VVPKLSSTGR  DLLQNLLKCN  PVQRISAEEA  LQHPYFADFC  PP  292
Nucleotide CDS Sequence (FASTA)
1     ATGCAAAAGT  ATGAGAAGCT  GGAGAAGATA  GGAGAGGGTA  CATATGGTAC  CGTTTTCAAG  60
61    GCTAAAAACA  GAGAAACGCA  CGAAATTGTG  GCCCTCAAAC  GAGTCCGACT  GGATGATGAT  120
121   GATGAGGGCG  TACCAAGTTC  AGCTTTACGA  GAAATTTGCC  TCCTGAAAGA  ACTGAAGCAT  180
181   AAAAACATTG  TAAGGTTACA  TGACGTCCTT  CACAGTGATA  AGAAACTCAC  ATTAGTGTTT  240
241   GAATACTGTG  ATCAGGATTT  GAAGAAATAC  TTTGACAGCT  GTAATGGTGA  CTTGGATCCA  300
301   GAGATTGTCA  AGTCTTTTAT  GTACCAGTTG  TTGAAGGGTC  TCGCCTTCTG  CCACAGCAGA  360
361   AATGTTCTCC  ACCGTGACCT  TAAACCACAA  AACCTGCTCA  TCAACAGAAA  CGGGGAACTG  420
421   AAGTTGGCTG  ATTTCGGCTT  GGCCAGAGCG  TTTGGGATCC  CTGTACGCTG  TTATTCTGCT  480
481   GAGGTGGTGA  CGTTGTGGTA  CAGGCCTCCG  GATGTACTGT  TTGGTGCTAA  ACTCTACTCT  540
541   ACCTCTATCG  ACATGTGGTC  TGCAGGCTGT  ATATTTGCAG  AACTGGCAAA  TGCAGGACGG  600
601   CCTTTATTTC  CTGGTAACGA  TGTGGACGAT  CAGCTAAAGA  GGATCTTTCG  ATTGCTGGGA  660
661   ACGCCAACAG  AAGAACAGTG  GCAGACTATG  AATAAACTTC  CAGATTATAA  GCCGTACCCG  720
721   ATGTATCCAG  CTACTACATC  ACTTGTGAAC  GTCGTGCCGA  AACTCAGCAG  CACCGGCAGA  780
781   GATTTACTAC  AGAATCTTCT  GAAATGTAAT  CCAGTACAGC  GAATCTCAGC  AGAAGAAGCT  840
841   CTACAGCACC  CTTACTTTGC  TGATTTCTGC  CCACCATAA  879

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
RAINMIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Icp-3174Ictalurus punctatus99.660.0 605
LLPS-Asm-1466Astyanax mexicanus99.660.0 605
LLPS-Gaa-2471Gasterosteus aculeatus99.320.0 603
LLPS-Scm-2302Scophthalmus maximus99.240.0 544
LLPS-Pof-3494Poecilia formosa98.970.0 600
LLPS-Orn-3209Oreochromis niloticus98.970.0 600
LLPS-Xim-1047Xiphophorus maculatus98.970.0 600
LLPS-Ten-1622Tetraodon nigroviridis98.966e-138 396
LLPS-Orl-2285Oryzias latipes98.630.0 598
LLPS-Scf-4044Scleropages formosus98.290.0 596
LLPS-Chs-3673Chlorocebus sabaeus98.168e-156 441
LLPS-Gaga-1592Gallus gallus97.730.0 535
LLPS-Tut-1375Tursiops truncatus96.920.0 592
LLPS-Lac-3929Latimeria chalumnae96.810.0 564
LLPS-Fec-0918Felis catus96.580.0 590
LLPS-Hos-3414Homo sapiens96.580.0 590
LLPS-Man-4853Macaca nemestrina96.580.0 590
LLPS-Rhb-4268Rhinopithecus bieti96.580.0 590
LLPS-Orc-2500Oryctolagus cuniculus96.580.0 590
LLPS-Poa-3557Pongo abelii96.580.0 590
LLPS-Cas-3997Carlito syrichta96.580.0 590
LLPS-Maf-4001Macaca fascicularis96.580.0 590
LLPS-Mum-1840Mus musculus96.580.0 590
LLPS-Mea-1810Mesocricetus auratus96.580.0 590
LLPS-Sus-2868Sus scrofa96.580.0 590
LLPS-Cea-1697Cercocebus atys96.580.0 590
LLPS-Caj-2546Callithrix jacchus96.580.0 590
LLPS-Tar-2944Takifugu rubripes96.580.0 564
LLPS-Bot-2779Bos taurus96.580.0 590
LLPS-Dio-3851Dipodomys ordii96.580.0 590
LLPS-Mup-4147Mustela putorius furo96.580.0 590
LLPS-Ova-4457Ovis aries96.580.0 590
LLPS-Caf-1949Canis familiaris96.430.0 563
LLPS-Loa-1709Loxodonta africana96.230.0 588
LLPS-Cap-4470Cavia porcellus96.230.0 589
LLPS-Ict-3060Ictidomys tridecemlineatus96.230.0 589
LLPS-Ran-3784Rattus norvegicus96.230.0 587
LLPS-Aim-4278Ailuropoda melanoleuca96.230.0 588
LLPS-Otg-1088Otolemur garnettii95.920.0 585
LLPS-Fud-1137Fukomys damarensis95.890.0 588
LLPS-Myl-1946Myotis lucifugus95.580.0 584
LLPS-Mam-2790Macaca mulatta94.440.0 570
LLPS-Eqc-1030Equus caballus94.180.0 570
LLPS-Mod-3156Monodelphis domestica94.160.0 534
LLPS-Urm-1752Ursus maritimus93.40.0 560
LLPS-Paa-3499Papio anubis93.380.0 582
LLPS-Mal-3628Mandrillus leucophaeus93.380.0 582
LLPS-Sah-1365Sarcophilus harrisii90.850.0 566
LLPS-Pat-3670Pan troglodytes90.350.0 571
LLPS-Aon-1553Aotus nancymaae89.810.0 572
LLPS-Pap-4192Pan paniscus88.120.0 568
LLPS-Nol-1401Nomascus leucogenys88.120.0 568
LLPS-Gog-3371Gorilla gorilla88.120.0 568
LLPS-Ere-0550Erinaceus europaeus87.31e-118 345
LLPS-Drm-1504Drosophila melanogaster79.511e-170 482
LLPS-Cis-0747Ciona savignyi75.781e-166 472
LLPS-Xet-0104Xenopus tropicalis69.82e-135 392
LLPS-Php-1553Physcomitrella patens61.573e-112 333
LLPS-Cog-1179Colletotrichum gloeosporioides61.384e-126 370
LLPS-Ved-1471Verticillium dahliae61.381e-126 371
LLPS-Anc-0432Anolis carolinensis61.052e-121 358
LLPS-Pes-1450Pelodiscus sinensis60.762e-120 355
LLPS-Dac-2158Daucus carota60.753e-124 364
LLPS-Fia-2947Ficedula albicollis60.07e-120 353
LLPS-Tag-0897Taeniopygia guttata60.02e-119 353
LLPS-Meg-0197Meleagris gallopavo59.938e-122 358
LLPS-Anp-0015Anas platyrhynchos59.934e-121 357
LLPS-Gor-0809Gossypium raimondii59.88e-124 363
LLPS-Zem-0612Zea mays59.791e-122 360
LLPS-Sei-0824Setaria italica59.791e-122 360
LLPS-Mua-1443Musa acuminata59.633e-112 333
LLPS-Sol-1455Solanum lycopersicum59.597e-119 350
LLPS-Orbr-2318Oryza brachyantha59.524e-123 361
LLPS-Amt-0592Amborella trichopoda59.527e-122 358
LLPS-Thc-0590Theobroma cacao59.523e-121 357
LLPS-Abg-1847Absidia glauca59.527e-119 350
LLPS-Met-1934Medicago truncatula59.466e-122 358
LLPS-Orp-1368Oryza punctata59.459e-124 362
LLPS-Orm-0109Oryza meridionalis59.456e-122 362
LLPS-Tra-2889Triticum aestivum59.457e-122 358
LLPS-Brd-0344Brachypodium distachyon59.458e-121 355
LLPS-Chc-0450Chondrus crispus59.311e-120 355
LLPS-Asn-1476Aspergillus nidulans59.232e-120 357
LLPS-Scj-0017Schizosaccharomyces japonicus59.232e-112 333
LLPS-Chr-0750Chlamydomonas reinhardtii59.175e-117 347
LLPS-Prp-0601Prunus persica59.125e-121 356
LLPS-Sot-0720Solanum tuberosum59.121e-122 360
LLPS-Sob-1321Sorghum bicolor59.111e-121 357
LLPS-Sem-0666Selaginella moellendorffii59.111e-118 350
LLPS-Ors-0422Oryza sativa58.971e-120 358
LLPS-Orr-1502Oryza rufipogon58.972e-120 357
LLPS-Ori-0841Oryza indica58.972e-121 358
LLPS-Orni-1237Oryza nivara58.972e-120 358
LLPS-Orgl-1850Oryza glumaepatula58.972e-121 358
LLPS-Kop-0343Komagataella pastoris58.824e-114 338
LLPS-Phv-1115Phaseolus vulgaris58.789e-120 352
LLPS-Mae-1428Manihot esculenta58.781e-121 357
LLPS-Glm-2912Glycine max58.789e-121 355
LLPS-Via-1054Vigna angularis58.789e-120 352
LLPS-Lep-0298Leersia perrieri58.763e-123 363
LLPS-Org-1121Oryza glaberrima58.624e-120 356
LLPS-Orb-1847Oryza barthii58.624e-120 357
LLPS-Dos-1566Dothistroma septosporum58.52e-116 345
LLPS-Hov-1882Hordeum vulgare58.483e-122 360
LLPS-Viv-1581Vitis vinifera58.453e-119 351
LLPS-Cus-1035Cucumis sativus58.453e-120 353
LLPS-Nia-0305Nicotiana attenuata58.223e-121 356
LLPS-Gag-1449Gaeumannomyces graminis58.226e-121 358
LLPS-Map-0891Magnaporthe poae58.224e-121 358
LLPS-Aso-0621Aspergillus oryzae58.227e-120 353
LLPS-Asf-0029Aspergillus flavus58.227e-120 353
LLPS-Zyt-0938Zymoseptoria tritici58.162e-116 345
LLPS-Hea-1239Helianthus annuus58.113e-121 356
LLPS-Pot-0900Populus trichocarpa57.911e-118 350
LLPS-Crn-0512Cryptococcus neoformans57.591e-114 340
LLPS-Yal-0878Yarrowia lipolytica57.442e-115 341
LLPS-Asg-1202Ashbya gossypii57.341e-113 337
LLPS-Miv-0332Microbotryum violaceum57.241e-113 337
LLPS-Brr-2134Brassica rapa57.199e-117 345
LLPS-Osl-0682Ostreococcus lucimarinus57.191e-112 334
LLPS-Brn-2656Brassica napus57.192e-115 345
LLPS-Art-0331Arabidopsis thaliana56.851e-116 344
LLPS-Arl-1464Arabidopsis lyrata56.859e-117 345
LLPS-Bro-1778Brassica oleracea56.74e-116 343
LLPS-Usm-0052Ustilago maydis56.615e-113 335
LLPS-Gas-0038Galdieria sulphuraria56.541e-116 345