LLPS-Dar-2913
yme1l1a

▼ OVERVIEW

Status: Unreviewed
Protein Name: YME1-like 1a
Gene Name: yme1l1a
Ensembl Gene: ENSDARG00000075192.5
Ensembl Protein: ENSDARP00000104415.2
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFSLPTSFQS  QGTVPLTHLI  NVVQYLKSSA  NSAVTASVQS  LQKDLSPEHD  PLHYEPKVNL  60
61    KELGLSELRV  SHVRDVLERL  LPSTHPAEKS  FASVAQNSTA  WRTSHISAPS  FFQNKYGFSH  120
121   KHSGCFGSSV  FRRGGSSPLQ  AACVDLHHLQ  LWVQNRGFKT  MSKSRHLRSS  SEGPVEADNY  180
181   TPVFMKGLMM  KEKTDTGSLE  QLLKQNNLPE  SHQDAFKTGF  TEGFMKAQAL  TKRTQDSVKR  240
241   TRLIIFVLLL  AGIYGVSRSP  FFSGKGSFSD  TVRFRTTSGL  DSSVDPVQMK  NITFEHVKGV  300
301   EEAKNELQDV  VEFLRNPQKF  TVLGGKLPKG  ILLVGPPGTG  KTLLARAVAG  EADVPFYYAS  360
361   GSEFDEMFVG  VGASRIRNLF  KEAKASAPCV  IFIDELDSVG  GKRIESPMHP  YSRQTINQLL  420
421   AEMDGFKPNE  GVIVIGATNF  AEALDNALVR  PGRFDMQVTV  PIPDVKGRTE  ILEWYLKKIK  480
481   VDSAIDAEII  ARGTVGFSGA  ELENLVNQAA  LKAAADGKDL  VTMKELKFAK  DKILMGPERR  540
541   SVEIDKRNKT  ITAYHESGHA  IVAYYTKDAM  PINKATIMPR  GPSLGHVSLL  PENDRWSETR  600
601   AQLLAQMDVS  MGGRVAEELV  FGNDQITSGA  SSDFDGATKI  AQMMVTRFGM  SDKLGVMTYS  660
661   DLTKHSPETR  AAVEQEIRVL  LQSSYERAKK  ILKTYSKEHK  LLADALLTYE  TLNAKEIQMI  720
721   LEGKSLDPR  729
Nucleotide CDS Sequence (FASTA)
1     ATGTTTTCTC  TGCCTACAAG  CTTTCAGTCA  CAGGGAACAG  TGCCTTTGAC  CCATCTGATC  60
61    AATGTGGTCC  AGTACCTGAA  GAGTTCAGCC  AACTCGGCCG  TAACTGCATC  AGTACAGAGT  120
121   CTGCAGAAAG  ACCTTTCACC  TGAACACGAC  CCACTTCACT  ATGAGCCCAA  AGTAAACCTG  180
181   AAGGAGCTGG  GTCTGTCAGA  GCTGCGGGTC  AGTCATGTTC  GGGATGTTCT  GGAGCGCCTG  240
241   CTGCCTTCTA  CACACCCAGC  GGAGAAGTCC  TTCGCCAGCG  TGGCTCAAAA  CTCAACAGCA  300
301   TGGAGAACAT  CTCACATTTC  TGCCCCCTCC  TTCTTCCAAA  ACAAATATGG  GTTCTCTCAC  360
361   AAACACTCAG  GATGTTTTGG  CTCTTCAGTG  TTTCGCAGGG  GAGGTTCCAG  CCCCCTTCAG  420
421   GCAGCCTGTG  TAGATCTGCA  TCATCTGCAG  TTATGGGTCC  AAAACAGAGG  CTTCAAGACA  480
481   ATGTCCAAGA  GCAGACATCT  GCGCTCCAGT  TCTGAAGGTC  CAGTCGAGGC  AGATAATTAT  540
541   ACTCCAGTCT  TTATGAAGGG  CCTTATGATG  AAGGAAAAAA  CAGACACGGG  GAGTCTTGAG  600
601   CAGTTATTAA  AACAGAATAA  CTTGCCAGAA  TCTCATCAGG  ATGCTTTTAA  GACTGGTTTT  660
661   ACAGAGGGCT  TCATGAAGGC  TCAGGCTTTG  ACAAAGAGGA  CACAAGACTC  TGTGAAGAGG  720
721   ACACGTCTGA  TTATTTTTGT  TCTCCTACTG  GCGGGAATAT  ATGGTGTGTC  CAGAAGTCCT  780
781   TTCTTCTCGG  GTAAAGGATC  GTTTTCAGAC  ACTGTTCGCT  TTCGCACCAC  CTCTGGTCTG  840
841   GATTCATCCG  TGGACCCCGT  TCAGATGAAG  AACATCACAT  TCGAACATGT  GAAAGGAGTA  900
901   GAGGAGGCCA  AAAATGAACT  TCAGGATGTT  GTCGAATTTT  TGCGAAACCC  TCAGAAATTC  960
961   ACTGTGCTTG  GTGGTAAACT  TCCCAAAGGT  ATCCTGCTCG  TGGGGCCTCC  AGGAACAGGA  1020
1021  AAAACCCTGT  TGGCCAGAGC  TGTTGCCGGT  GAAGCAGACG  TGCCCTTCTA  CTACGCCTCT  1080
1081  GGGTCCGAGT  TTGATGAAAT  GTTTGTTGGA  GTCGGAGCGA  GTCGCATCAG  AAACCTTTTC  1140
1141  AAGGAGGCCA  AAGCTAGTGC  ACCATGTGTA  ATTTTCATCG  ATGAGCTGGA  TAGTGTAGGA  1200
1201  GGGAAAAGAA  TCGAGTCTCC  AATGCACCCA  TACTCCCGGC  AGACCATCAA  CCAACTGCTA  1260
1261  GCTGAGATGG  ATGGGTTTAA  ACCCAATGAA  GGGGTCATTG  TGATTGGAGC  TACAAACTTT  1320
1321  GCTGAAGCTC  TGGACAATGC  TCTAGTGAGA  CCAGGTCGGT  TTGACATGCA  GGTCACCGTC  1380
1381  CCAATCCCAG  ATGTGAAGGG  ACGCACAGAA  ATCCTGGAGT  GGTATTTGAA  AAAAATTAAA  1440
1441  GTGGATTCTG  CTATTGATGC  AGAGATCATT  GCAAGGGGAA  CGGTGGGCTT  TTCTGGAGCT  1500
1501  GAACTGGAGA  ACCTGGTGAA  TCAAGCAGCA  CTGAAAGCAG  CCGCCGATGG  GAAAGACCTG  1560
1561  GTGACCATGA  AAGAGCTGAA  GTTTGCCAAG  GATAAGATCC  TGATGGGCCC  AGAGCGCAGG  1620
1621  AGTGTAGAGA  TAGACAAAAG  AAATAAGACG  ATCACCGCTT  ATCATGAATC  AGGACACGCT  1680
1681  ATAGTGGCTT  ATTACACCAA  AGACGCAATG  CCTATCAACA  AAGCTACCAT  CATGCCGCGC  1740
1741  GGCCCATCAC  TTGGACATGT  GTCTTTGCTG  CCAGAGAATG  ACCGCTGGAG  TGAGACGCGG  1800
1801  GCTCAGCTGC  TAGCTCAGAT  GGACGTCAGT  ATGGGTGGCA  GAGTGGCTGA  AGAGCTGGTG  1860
1861  TTTGGAAATG  ATCAGATCAC  CTCCGGAGCA  TCCAGTGACT  TCGATGGAGC  CACTAAAATC  1920
1921  GCACAGATGA  TGGTGACACG  GTTTGGAATG  AGCGACAAGC  TGGGGGTCAT  GACCTACAGT  1980
1981  GACCTGACCA  AACACAGTCC  AGAGACACGA  GCAGCTGTAG  AACAGGAAAT  CAGAGTTCTT  2040
2041  CTGCAGAGTT  CGTATGAAAG  GGCAAAGAAG  ATCCTGAAGA  CCTACAGTAA  AGAACACAAG  2100
2101  CTGCTGGCTG  ATGCCCTGCT  GACTTACGAA  ACGCTCAATG  CCAAGGAAAT  TCAGATGATC  2160
2161  CTGGAAGGAA  AGTCGTTGGA  TCCCAGATGA  2190

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
MIST
Drug
CTD
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Leo-3512Lepisosteus oculatus86.134e-160 471
LLPS-Dio-1163Dipodomys ordii84.060.0 868
LLPS-Asm-3709Astyanax mexicanus80.110.01144
LLPS-Orn-1365Oreochromis niloticus79.470.01051
LLPS-Icp-3194Ictalurus punctatus77.790.01116
LLPS-Pof-0115Poecilia formosa76.440.01083
LLPS-Xim-2163Xiphophorus maculatus76.160.01075
LLPS-Mea-4353Mesocricetus auratus75.822e-156 468
LLPS-Scm-2991Scophthalmus maximus75.210.01070
LLPS-Scf-1640Scleropages formosus75.10.01074
LLPS-Orl-0692Oryzias latipes74.970.01046
LLPS-Tar-3329Takifugu rubripes74.520.01052
LLPS-Ten-3014Tetraodon nigroviridis74.420.01044
LLPS-Mal-1574Mandrillus leucophaeus73.820.0 993
LLPS-Lac-0608Latimeria chalumnae73.780.0 844
LLPS-Sah-0972Sarcophilus harrisii73.740.0 963
LLPS-Aim-2367Ailuropoda melanoleuca73.490.01003
LLPS-Pap-3155Pan paniscus73.080.01006
LLPS-Pat-3216Pan troglodytes73.080.01006
LLPS-Hos-1593Homo sapiens73.080.01005
LLPS-Pes-0943Pelodiscus sinensis72.980.01044
LLPS-Ora-0545Ornithorhynchus anatinus72.270.01018
LLPS-Mum-3470Mus musculus71.960.01045
LLPS-Ran-2666Rattus norvegicus71.820.01041
LLPS-Anc-2402Anolis carolinensis71.820.01026
LLPS-Ict-0493Ictidomys tridecemlineatus71.680.01042
LLPS-Mod-2889Monodelphis domestica71.680.0 995
LLPS-Orc-2223Oryctolagus cuniculus71.680.01044
LLPS-Cas-1222Carlito syrichta71.580.01045
LLPS-Fud-1023Fukomys damarensis71.530.01020
LLPS-Eqc-0153Equus caballus71.490.01024
LLPS-Rhb-2059Rhinopithecus bieti71.450.01024
LLPS-Chs-1231Chlorocebus sabaeus71.430.0 951
LLPS-Xet-0884Xenopus tropicalis71.370.01005
LLPS-Poa-2073Pongo abelii71.330.01034
LLPS-Sus-1650Sus scrofa71.140.01038
LLPS-Mup-4239Mustela putorius furo71.00.01036
LLPS-Urm-2995Ursus maritimus71.00.01034
LLPS-Fec-0613Felis catus71.00.01040
LLPS-Ova-0225Ovis aries70.780.01030
LLPS-Caf-0152Canis familiaris70.510.01033
LLPS-Bot-0509Bos taurus70.410.01014
LLPS-Loa-1345Loxodonta africana70.410.0 989
LLPS-Gog-4273Gorilla gorilla70.040.0 947
LLPS-Fia-0422Ficedula albicollis68.90.0 997
LLPS-Gaga-0109Gallus gallus68.670.0 986
LLPS-Tag-2205Taeniopygia guttata68.280.0 978
LLPS-Nol-4065Nomascus leucogenys68.050.01014
LLPS-Maf-1309Macaca fascicularis67.480.01006
LLPS-Mam-2238Macaca mulatta67.480.01006
LLPS-Paa-2497Papio anubis67.350.0 994
LLPS-Cea-1214Cercocebus atys67.050.01006
LLPS-Aon-0136Aotus nancymaae66.790.0 979
LLPS-Caj-0756Callithrix jacchus66.410.0 978
LLPS-Gaa-1077Gasterosteus aculeatus65.50.0 939
LLPS-Myl-2877Myotis lucifugus65.40.0 969
LLPS-Otg-4320Otolemur garnettii65.230.0 936
LLPS-Anp-1351Anas platyrhynchos64.160.0 947
LLPS-Meg-1822Meleagris gallopavo63.280.0 945
LLPS-Man-3830Macaca nemestrina62.720.0 927
LLPS-Cym-0740Cyanidioschyzon merolae59.233e-166 505
LLPS-Chc-1154Chondrus crispus59.031e-171 517
LLPS-Brr-2592Brassica rapa58.73e-169 503
LLPS-Sol-0458Solanum lycopersicum57.721e-167 507
LLPS-Sem-2107Selaginella moellendorffii57.626e-168 506
LLPS-Chr-0297Chlamydomonas reinhardtii57.371e-164 499
LLPS-Orgl-1447Oryza glumaepatula56.99e-164 517
LLPS-Ori-0602Oryza indica56.92e-171 516
LLPS-Orm-2102Oryza meridionalis56.91e-171 517
LLPS-Ors-2382Oryza sativa56.92e-171 516
LLPS-Via-1702Vigna angularis56.811e-156 481
LLPS-Orp-1821Oryza punctata56.88e-172 517
LLPS-Gas-1178Galdieria sulphuraria56.714e-170 515
LLPS-Orb-1766Oryza barthii56.682e-163 515
LLPS-Nia-2454Nicotiana attenuata56.62e-165 501
LLPS-Hea-2002Helianthus annuus56.566e-170 513
LLPS-Php-2388Physcomitrella patens56.562e-170 514
LLPS-Osl-0247Ostreococcus lucimarinus56.491e-157 478
LLPS-Dac-1973Daucus carota56.472e-168 509
LLPS-Orbr-0394Oryza brachyantha56.472e-166 503
LLPS-Drm-1869Drosophila melanogaster56.350.0 555
LLPS-Brd-0045Brachypodium distachyon56.181e-163 496
LLPS-Dos-0648Dothistroma septosporum56.142e-165 503
LLPS-Abg-1767Absidia glauca56.112e-162 492
LLPS-Brn-0638Brassica napus55.913e-168 508
LLPS-Gor-0131Gossypium raimondii55.912e-168 507
LLPS-Mae-2439Manihot esculenta55.913e-167 506
LLPS-Thc-1534Theobroma cacao55.794e-167 514
LLPS-Arl-1687Arabidopsis lyrata55.73e-167 506
LLPS-Zem-2092Zea mays55.79e-169 510
LLPS-Art-0121Arabidopsis thaliana55.74e-167 505
LLPS-Amt-2266Amborella trichopoda55.77e-170 509
LLPS-Sei-0782Setaria italica55.482e-167 506
LLPS-Cus-1625Cucumis sativus55.482e-166 503
LLPS-Coc-0866Corchorus capsularis55.482e-168 508
LLPS-Bro-0046Brassica oleracea55.489e-168 507
LLPS-Sob-0742Sorghum bicolor55.485e-168 508
LLPS-Zyt-0287Zymoseptoria tritici55.454e-155 489
LLPS-Met-0941Medicago truncatula55.436e-166 502
LLPS-Ved-0744Verticillium dahliae55.253e-157 481
LLPS-Mua-1758Musa acuminata55.23e-148 459
LLPS-Pot-0005Populus trichocarpa55.161e-164 499
LLPS-Orni-1862Oryza nivara55.057e-168 508
LLPS-Orr-1158Oryza rufipogon55.058e-168 507
LLPS-Lep-2136Leersia perrieri54.886e-158 482
LLPS-Tra-2614Triticum aestivum54.744e-165 500
LLPS-Crn-1461Cryptococcus neoformans54.732e-158 485
LLPS-Nec-1417Neurospora crassa54.675e-158 486
LLPS-Asn-1264Aspergillus nidulans54.674e-160 489
LLPS-Hov-2048Hordeum vulgare54.641e-161 493
LLPS-Tru-1821Triticum urartu54.641e-159 498
LLPS-Mao-0585Magnaporthe oryzae54.577e-158 483
LLPS-Asfu-0937Aspergillus fumigatus54.421e-154 476
LLPS-Prp-0120Prunus persica54.414e-164 498
LLPS-Viv-1802Vitis vinifera54.416e-159 484
LLPS-Glm-2659Glycine max54.292e-164 498
LLPS-Phv-2014Phaseolus vulgaris54.272e-166 503
LLPS-Nef-1214Neosartorya fischeri54.29e-154 474
LLPS-Scj-0130Schizosaccharomyces japonicus54.152e-149 460
LLPS-Sot-1642Solanum tuberosum54.142e-148 461
LLPS-Blg-1405Blumeria graminis53.744e-156 481
LLPS-Asni-1325Aspergillus niger53.741e-152 471
LLPS-Ast-1012Aspergillus terreus53.742e-153 473
LLPS-Miv-1232Microbotryum violaceum53.516e-155 478
LLPS-Asc-1010Aspergillus clavatus53.191e-154 476
LLPS-Aso-0925Aspergillus oryzae52.834e-152 467
LLPS-Asf-0535Aspergillus flavus52.835e-153 466
LLPS-Coo-0554Colletotrichum orbiculare52.42e-159 487
LLPS-Cogr-0547Colletotrichum graminicola52.42e-155 476
LLPS-Tum-0583Tuber melanosporum52.32e-154 476
LLPS-Gag-0868Gaeumannomyces graminis52.22e-138 433
LLPS-Scs-0679Sclerotinia sclerotiorum52.152e-149 462
LLPS-Mel-0989Melampsora laricipopulina51.859e-142 443
LLPS-Pytr-0296Pyrenophora triticirepentis51.332e-141 441
LLPS-Kop-1247Komagataella pastoris51.172e-159 484
LLPS-Scp-0441Schizosaccharomyces pombe51.112e-160 488
LLPS-Lem-0241Leptosphaeria maculans50.881e-142 444
LLPS-Yal-1177Yarrowia lipolytica50.712e-155 475
LLPS-Fus-0277Fusarium solani50.662e-142 445
LLPS-Fuv-1458Fusarium verticillioides50.642e-147 455
LLPS-Fuo-0410Fusarium oxysporum50.644e-147 454
LLPS-Phn-0900Phaeosphaeria nodorum50.576e-140 436
LLPS-Sac-1177Saccharomyces cerevisiae50.523e-151 466
LLPS-Vir-0476Vigna radiata49.891e-120 395
LLPS-Scc-0903Schizosaccharomyces cryophilus49.84e-156 476
LLPS-Trr-0810Trichoderma reesei49.785e-141 439
LLPS-Asg-0073Ashbya gossypii49.592e-152 468
LLPS-Trv-1388Trichoderma virens49.467e-140 438
LLPS-Pug-0930Puccinia graminis49.026e-140 437
LLPS-Pyt-0325Pyrenophora teres47.792e-124 397
LLPS-Beb-1015Beauveria bassiana47.695e-142 441
LLPS-Cae-0464Caenorhabditis elegans47.093e-177 531
LLPS-Cis-0139Ciona savignyi47.064e-148 454
LLPS-Put-0997Puccinia triticina46.622e-131 413