LLPS-Dar-2247
rbl2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Retinoblastoma-like 2 (p130)
Gene Name: rbl2
Ensembl Gene: ENSDARG00000045636.7
Ensembl Protein: ENSDARP00000148064.1
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Perinucleolar compartmentPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSEEEDTLGK  TKHAFEELCR  DLNMDEESSN  RAWRSYENIS  KNYTLEGSEL  HWLACSLYVA  60
61    CRSSVPTMSK  GTAEGNYVSL  TRILRSSQQS  LIEFFSKMKK  WQDMANLPRD  FQQSTEKLER  120
121   NFTVTSVIFK  KYLPLFRDIF  KTPTDELPRT  HRGRKQRRHP  CTVTEVFNFC  WILFIHAKGN  180
181   FPMISDDLVN  SYHLLLCALD  LVYCNALLCS  SRKDLLNPAF  KGLPEDFNSK  DYKPGPGSLC  240
241   FIEQLCELHD  GLVLEAKGAK  EHFWKPFIKK  LFERKILKGK  EDTLTGFLEP  VNFGDSLASL  300
301   NRVYEEHVLS  SGSLDERIFL  GDGAREDIGT  PGPYEGIENQ  DRANNPLQNS  MTASALRVST  360
361   PLTGRRYVPE  SIVGTPVSSA  MQSVGRLHTL  LTGFKYRPSV  KLRDIFRSCV  RDPTESVAAR  420
421   LKEMSEIFLQ  NYEGTGDDNK  SLARDIAVKY  FCLAEALYYK  SLEVIINQEK  KRLGDVDLSG  480
481   VLEQDVFHRS  LIACCLEIVI  FSYRPPGEFP  RVLQIFDLPA  YHFYKVIEVL  VRAEEGLFRE  540
541   VVKHLNHVEE  QVLESLAWKG  NSPLWERIRE  AKNCVPTCQE  VMPPQHLEDG  SGSNANTPSS  600
601   KTEFSGNIAA  GAGKGVSPSP  TSLHDRYSSP  PTGTAVRRLF  VDGDTTPEPA  PPVKVAPPSI  660
661   VSSIPAGQTV  VTMATATVTA  NNGQTVTIPV  QGIANESGGI  TFIPVQVSVT  SQAGATLPTL  720
721   SAQTLTGTLT  TQQLTTTPMG  AVQNNPSPPK  QDKKTPQQGT  PTKRAQKTGS  LCLFFRKVYH  780
781   LASVRLRDLC  AKLDISADLR  RKIWTCFEYS  LVHCTDLMMD  RHLDQLLMCA  IYVMTKVTKE  840
841   DKSFQNIMKC  YRSQPQASSS  VYRSVLISGR  KRRHSGNTEN  THRQSSPTEG  AQEQASGESS  900
901   PVSMRSSSTL  PIPQPSSAPS  TPTRAPGGPQ  EQEEERGDLI  RFYNHVYIKQ  IKPFALRYSS  960
961   NSPKNGQAET  PPLCPYPSLR  IGSPRRVLLS  HNHSIYISPH  KTGSPISPRD  KIFYYVSSSP  1020
1021  SHRLREINTM  IRTGETPTKK  RSIALEEEQQ  SPAKRLCQEN  QTALLRRLQD  VANDRSSSH  1079
Nucleotide CDS Sequence (FASTA)
1     ATGAGCGAGG  AGGAAGACAC  ATTGGGGAAA  ACTAAACATG  CATTTGAAGA  ACTGTGTCGA  60
61    GATCTGAATA  TGGATGAGGA  GTCGAGTAAC  CGAGCCTGGA  GGAGTTATGA  AAATATCAGC  120
121   AAGAATTACA  CTCTGGAGGG  CAGTGAGCTG  CACTGGTTGG  CGTGTTCTCT  GTATGTTGCG  180
181   TGTCGCTCAT  CAGTGCCCAC  TATGAGTAAA  GGCACGGCGG  AGGGAAACTA  CGTGTCTCTG  240
241   ACCAGGATCC  TGCGCTCATC  ACAGCAGAGC  CTGATTGAGT  TCTTCAGTAA  GATGAAGAAG  300
301   TGGCAGGACA  TGGCGAATCT  GCCCAGAGAC  TTCCAGCAGA  GCACAGAGAA  ACTGGAGAGG  360
361   AACTTCACCG  TCACCTCCGT  CATCTTCAAG  AAATACCTGC  CCTTATTCAG  AGACATCTTC  420
421   AAGACACCCA  CGGACGAGTT  ACCCAGAACA  CACCGGGGCA  GAAAACAGAG  ACGTCATCCC  480
481   TGCACCGTCA  CTGAGGTCTT  CAACTTCTGC  TGGATCCTCT  TCATACACGC  TAAAGGAAAC  540
541   TTCCCAATGA  TCAGCGATGA  CCTGGTGAAC  TCGTATCATC  TGCTGCTCTG  TGCTCTGGAT  600
601   CTGGTTTATT  GTAACGCGCT  GCTGTGCTCG  AGCCGGAAAG  ATCTGCTCAA  CCCAGCCTTT  660
661   AAAGGGTTGC  CTGAGGACTT  CAACAGTAAA  GATTATAAGC  CGGGCCCGGG  TTCGTTATGT  720
721   TTCATAGAGC  AGCTTTGTGA  GCTTCACGAT  GGTCTGGTGC  TGGAGGCCAA  AGGAGCTAAA  780
781   GAGCATTTCT  GGAAACCCTT  CATTAAGAAA  TTGTTTGAGC  GAAAGATTCT  GAAAGGAAAG  840
841   GAGGACACGC  TGACAGGATT  TTTGGAGCCA  GTGAATTTCG  GTGACAGTCT  GGCGTCTCTG  900
901   AACCGTGTGT  ATGAAGAACA  TGTCCTGTCA  TCCGGTTCTC  TGGATGAGCG  AATATTTCTG  960
961   GGAGATGGAG  CTAGAGAAGA  CATCGGCACA  CCAGGACCTT  ACGAAGGGAT  AGAGAACCAG  1020
1021  GACAGAGCGA  ACAACCCACT  GCAGAACTCG  ATGACGGCGT  CTGCCCTCAG  AGTGTCCACT  1080
1081  CCATTGACAG  GCAGGAGGTA  CGTGCCGGAG  AGCATTGTGG  GGACTCCTGT  TTCCAGCGCC  1140
1141  ATGCAGAGTG  TGGGCCGACT  GCACACCCTG  CTGACGGGAT  TCAAATACAG  GCCCAGCGTC  1200
1201  AAACTCAGAG  ATATATTTAG  ATCCTGTGTA  AGAGACCCCA  CAGAGTCAGT  AGCAGCCAGA  1260
1261  CTGAAGGAGA  TGTCCGAGAT  TTTCCTTCAG  AATTATGAGG  GAACCGGAGA  CGACAACAAG  1320
1321  AGCCTGGCGA  GAGATATCGC  AGTGAAGTAT  TTTTGCTTGG  CGGAGGCACT  TTACTATAAA  1380
1381  TCCCTGGAGG  TGATCATCAA  CCAGGAGAAG  AAACGTCTTG  GAGACGTGGA  CCTGTCTGGC  1440
1441  GTTCTGGAGC  AGGATGTGTT  TCACCGCTCG  CTGATCGCCT  GCTGTCTGGA  GATCGTCATC  1500
1501  TTCTCCTATA  GACCACCAGG  AGAGTTTCCC  AGAGTCCTGC  AAATCTTTGA  CCTCCCCGCT  1560
1561  TATCACTTTT  ACAAGGTGAT  CGAGGTGTTG  GTACGAGCTG  AGGAGGGTCT  TTTCCGGGAG  1620
1621  GTGGTCAAAC  ATCTGAACCA  TGTCGAGGAG  CAGGTGCTGG  AGTCTTTGGC  ATGGAAAGGA  1680
1681  AACTCCCCGC  TGTGGGAGCG  AATCAGAGAG  GCCAAAAACT  GTGTTCCCAC  CTGCCAGGAG  1740
1741  GTAATGCCAC  CTCAACACCT  AGAGGACGGT  TCAGGAAGCA  ACGCAAACAC  CCCAAGCAGC  1800
1801  AAGACTGAAT  TCAGCGGCAA  CATCGCAGCG  GGAGCAGGAA  AAGGAGTTTC  TCCGTCCCCT  1860
1861  ACATCTCTCC  ACGACCGCTA  CAGTTCTCCC  CCTACTGGCA  CAGCAGTTCG  TCGTCTTTTT  1920
1921  GTGGATGGAG  ACACGACGCC  AGAACCTGCT  CCACCTGTCA  AAGTGGCACC  GCCGTCTATA  1980
1981  GTCAGCTCCA  TCCCAGCAGG  ACAGACTGTG  GTTACGATGG  CAACAGCTAC  TGTCACAGCG  2040
2041  AACAACGGCC  AGACTGTTAC  CATACCTGTT  CAAGGAATAG  CGAATGAGAG  TGGAGGAATC  2100
2101  ACATTTATCC  CAGTGCAAGT  GAGTGTGACG  AGTCAGGCTG  GAGCGACTCT  GCCAACCCTC  2160
2161  AGTGCGCAGA  CTCTGACAGG  CACCCTGACC  ACTCAGCAGC  TCACAACAAC  ACCTATGGGC  2220
2221  GCCGTGCAAA  ACAACCCCAG  CCCTCCCAAA  CAGGACAAAA  AGACACCTCA  GCAGGGAACA  2280
2281  CCCACCAAAC  GGGCCCAGAA  AACAGGCTCT  CTCTGCCTGT  TCTTCCGCAA  GGTGTATCAT  2340
2341  CTAGCTAGTG  TGCGTCTCAG  AGACTTGTGT  GCGAAACTGG  ACATCAGTGC  GGATCTGCGC  2400
2401  AGGAAGATCT  GGACCTGTTT  CGAGTATTCG  CTTGTCCACT  GCACCGACCT  CATGATGGAC  2460
2461  CGACATCTTG  ACCAGCTCCT  CATGTGCGCC  ATCTACGTCA  TGACTAAGGT  GACGAAAGAG  2520
2521  GACAAGTCGT  TCCAGAACAT  CATGAAGTGC  TACAGATCTC  AGCCTCAGGC  CAGCAGCAGT  2580
2581  GTGTACAGAA  GTGTGCTGAT  CTCTGGGAGA  AAGAGACGAC  ACTCTGGAAA  CACTGAAAAC  2640
2641  ACCCACAGAC  AGAGCTCACC  CACTGAGGGA  GCACAAGAAC  AAGCAAGCGG  TGAGAGCAGT  2700
2701  CCCGTGTCCA  TGCGCTCCAG  CAGTACGCTG  CCCATTCCCC  AGCCTAGCAG  CGCTCCATCC  2760
2761  ACCCCGACCC  GGGCACCGGG  AGGGCCCCAG  GAGCAGGAGG  AGGAGCGGGG  GGACCTCATC  2820
2821  CGCTTCTACA  ACCACGTCTA  CATCAAACAG  ATCAAACCCT  TCGCTCTGCG  CTACTCCAGC  2880
2881  AACTCGCCCA  AAAATGGGCA  GGCTGAAACT  CCTCCGCTCT  GTCCGTATCC  GTCGCTGCGC  2940
2941  ATCGGCTCTC  CACGCCGCGT  CCTCCTATCC  CACAATCACT  CCATCTACAT  CTCTCCGCAC  3000
3001  AAGACCGGCA  GCCCCATATC  TCCACGAGAC  AAAATCTTCT  ACTACGTCAG  CTCCAGCCCG  3060
3061  TCACACCGGC  TCCGAGAGAT  CAACACCATG  ATCCGAACCG  GAGAGACGCC  CACCAAGAAG  3120
3121  CGCAGCATCG  CTCTGGAGGA  AGAGCAGCAG  TCTCCTGCTA  AAAGACTGTG  TCAGGAGAAC  3180
3181  CAGACGGCGC  TGCTCAGACG  CCTGCAGGAC  GTGGCTAATG  ACCGCAGCTC  CTCACACTGA  3240

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
MIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-4101Astyanax mexicanus78.30.01657
LLPS-Icp-1397Ictalurus punctatus77.330.01632
LLPS-Leo-2003Lepisosteus oculatus69.410.01412
LLPS-Orn-2022Oreochromis niloticus68.020.01448
LLPS-Scf-1052Scleropages formosus67.00.01384
LLPS-Xim-2947Xiphophorus maculatus65.180.01387
LLPS-Pof-2938Poecilia formosa65.00.01380
LLPS-Gaa-1492Gasterosteus aculeatus63.710.01318
LLPS-Lac-1793Latimeria chalumnae62.740.01286
LLPS-Mod-2593Monodelphis domestica61.670.01272
LLPS-Fec-3858Felis catus61.550.01242
LLPS-Pat-4485Pan troglodytes61.410.01252
LLPS-Otg-3649Otolemur garnettii61.390.01239
LLPS-Anc-3661Anolis carolinensis61.380.01209
LLPS-Ora-0990Ornithorhynchus anatinus61.370.01153
LLPS-Ova-0268Ovis aries61.320.01253
LLPS-Caj-2332Callithrix jacchus61.320.01249
LLPS-Pes-2058Pelodiscus sinensis61.310.01197
LLPS-Nol-0364Nomascus leucogenys61.260.01243
LLPS-Mup-2801Mustela putorius furo61.230.01250
LLPS-Aon-0930Aotus nancymaae61.230.01246
LLPS-Eqc-3828Equus caballus61.230.01258
LLPS-Caf-4452Canis familiaris61.230.01250
LLPS-Gog-1100Gorilla gorilla61.140.01249
LLPS-Hos-3383Homo sapiens61.140.01251
LLPS-Aim-0363Ailuropoda melanoleuca61.050.01249
LLPS-Chs-0147Chlorocebus sabaeus61.050.01249
LLPS-Pap-0753Pan paniscus61.050.01249
LLPS-Maf-3714Macaca fascicularis61.00.01243
LLPS-Mam-4577Macaca mulatta61.00.01241
LLPS-Man-1584Macaca nemestrina61.00.01243
LLPS-Paa-0157Papio anubis60.960.01247
LLPS-Cea-3943Cercocebus atys60.960.01245
LLPS-Ict-1601Ictidomys tridecemlineatus60.920.01234
LLPS-Orc-0749Oryctolagus cuniculus60.920.01250
LLPS-Mum-1190Mus musculus60.870.01228
LLPS-Mal-1102Mandrillus leucophaeus60.780.01247
LLPS-Tar-1005Takifugu rubripes60.760.01237
LLPS-Urm-2364Ursus maritimus60.660.01212
LLPS-Poa-0694Pongo abelii60.60.01246
LLPS-Tut-0943Tursiops truncatus60.520.01249
LLPS-Ran-4211Rattus norvegicus60.510.01215
LLPS-Gaga-3723Gallus gallus60.430.01226
LLPS-Tag-2239Taeniopygia guttata60.380.01242
LLPS-Loa-2365Loxodonta africana60.270.01224
LLPS-Sus-0048Sus scrofa60.250.01248
LLPS-Cas-3486Carlito syrichta60.230.01246
LLPS-Mea-3141Mesocricetus auratus59.980.01237
LLPS-Fud-0362Fukomys damarensis59.960.01229
LLPS-Rhb-1710Rhinopithecus bieti59.60.01197
LLPS-Fia-0214Ficedula albicollis59.280.01249
LLPS-Meg-0471Meleagris gallopavo59.180.01178
LLPS-Sah-0871Sarcophilus harrisii58.880.01164
LLPS-Bot-4726Bos taurus58.70.01177
LLPS-Xet-2290Xenopus tropicalis58.10.01186
LLPS-Myl-4174Myotis lucifugus57.450.0 769
LLPS-Cap-3167Cavia porcellus57.430.01127
LLPS-Dio-0601Dipodomys ordii57.130.01091
LLPS-Drm-2064Drosophila melanogaster50.02e-21 105
LLPS-Anp-0798Anas platyrhynchos47.460.0 904
LLPS-Scm-3534Scophthalmus maximus45.580.0 892
LLPS-Ten-2397Tetraodon nigroviridis45.230.0 848
LLPS-Orl-3418Oryzias latipes44.450.0 847
LLPS-Cii-1661Ciona intestinalis42.452e-50 199
LLPS-Chr-0064Chlamydomonas reinhardtii39.395e-1274.7
LLPS-Cis-0811Ciona savignyi36.520.0 587
LLPS-Cae-0289Caenorhabditis elegans35.293e-1482.0
LLPS-Sem-0479Selaginella moellendorffii35.156e-23 110
LLPS-Gas-0482Galdieria sulphuraria33.731e-1070.1
LLPS-Zem-0701Zea mays33.643e-1585.1
LLPS-Osl-1062Ostreococcus lucimarinus33.331e-1276.6
LLPS-Pot-0460Populus trichocarpa33.18e-1687.0
LLPS-Hov-0958Hordeum vulgare32.775e-0655.1
LLPS-Orgl-2367Oryza glumaepatula32.692e-1275.5
LLPS-Ori-0516Oryza indica32.694e-1275.1
LLPS-Orb-0379Oryza barthii32.692e-1275.5
LLPS-Orr-1887Oryza rufipogon32.692e-1275.5
LLPS-Org-1267Oryza glaberrima32.693e-1275.5
LLPS-Ors-0722Oryza sativa32.694e-1275.1
LLPS-Orbr-1017Oryza brachyantha32.691e-1173.6
LLPS-Tra-2183Triticum aestivum32.55e-0655.1
LLPS-Cym-0695Cyanidioschyzon merolae32.281e-0656.6
LLPS-Nia-1350Nicotiana attenuata31.863e-1481.6
LLPS-Hea-0274Helianthus annuus31.57e-1584.0
LLPS-Sob-1274Sorghum bicolor31.435e-1687.8
LLPS-Prp-0146Prunus persica31.218e-1687.0
LLPS-Mua-1718Musa acuminata30.943e-1482.0
LLPS-Gor-0550Gossypium raimondii30.894e-1481.6
LLPS-Orni-0651Oryza nivara30.832e-1482.4
LLPS-Orm-0801Oryza meridionalis30.839e-1480.1
LLPS-Orp-1144Oryza punctata30.832e-1379.7
LLPS-Arl-0273Arabidopsis lyrata30.712e-1482.4
LLPS-Sei-0136Setaria italica30.718e-1687.0
LLPS-Bro-1684Brassica oleracea30.711e-1483.2
LLPS-Art-2420Arabidopsis thaliana30.712e-1482.8
LLPS-Mae-0064Manihot esculenta30.572e-28 127
LLPS-Viv-1309Vitis vinifera30.53e-1688.6
LLPS-Thc-0742Theobroma cacao30.238e-1377.0
LLPS-Sot-0789Solanum tuberosum30.225e-1687.8
LLPS-Sol-1268Solanum lycopersicum30.224e-1687.8
LLPS-Vir-0826Vigna radiata30.075e-1378.2
LLPS-Lep-0048Leersia perrieri30.03e-1378.6
LLPS-Glm-0725Glycine max29.795e-1584.3
LLPS-Coc-0627Corchorus capsularis29.463e-1172.4
LLPS-Dac-0207Daucus carota29.22e-1275.9
LLPS-Cus-0291Cucumis sativus29.133e-1481.6
LLPS-Amt-0401Amborella trichopoda29.137e-1377.4
LLPS-Phv-0308Phaseolus vulgaris29.082e-1379.0
LLPS-Brn-1941Brassica napus28.869e-1583.6
LLPS-Brr-1415Brassica rapa28.868e-1583.6
LLPS-Chc-0159Chondrus crispus26.399e-0860.5
LLPS-Php-0994Physcomitrella patens26.132e-1895.5
LLPS-Brd-0224Brachypodium distachyon25.83e-20 101
LLPS-Met-2058Medicago truncatula25.325e-27 123