LLPS-Dar-1529
rabgap1

▼ OVERVIEW

Status: Unreviewed
Protein Name: RAB GTPase-activating protein 1
Gene Name: rabgap1
Ensembl Gene: ENSDARG00000098967.3
Ensembl Protein: ENSDARP00000133354.1
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDPSVTELVV  GPDHLGQGDH  GYPTTAVPSR  SGSVPPKLEI  VLPIQGAQES  ELNERSYRDE  60
61    PSDLSPGTPV  PDEDSVVFSK  LTYLGCASVN  APRSEVEALR  MVSILRSQCQ  MPLDVTLSVP  120
121   GVSEGTVRLL  DPQSSTEIAN  YPIYKILFCV  RGHDGTPESD  CFAFTESHYN  TEIFRIHVFR  180
181   CEIQEAVSRI  LYSFATAFRR  SANKAPLATK  APPLTPDSDV  FTFTVSLEIK  EDDGKGTFSA  240
241   VSKDKDRQSF  KLRAGMDKKI  VIYVQQTSNK  ELAIERCFGL  LLSPGKNVKN  SDMHLLDLES  300
301   MGKSSDGKSY  IITGSWNPNT  PQFQAVNEET  PKDKFMYMTT  AVDLVITEVE  EPVRFLLETR  360
361   VRVCSPNERL  FWPFSKRSYT  ETFYLKLRQM  ENKERKSNSD  TLYEVMSLES  ETERERRKTT  420
421   ASPGVLSSGS  HGSTVPSPPE  DDEEEDNDEP  LLSGSGDVSK  ECAEKILETW  GELLSRWHLN  480
481   LAVRPKQLPA  LVRSGVPEAL  RGEVWQLLAG  CHNNDHLVEE  YRTLITKESP  QDSAITRDIN  540
541   RTFPAHDYFK  DTGGDGQDSL  YKICKAYSVY  DEEIGYCQGQ  SFLAAVLLLH  MPEEQAFSVL  600
601   VKIMFEYGLR  ELFKQNFEDL  HCKFFQLERL  MQECIPDLYT  HFLNLGLEAH  MYASQWFLTL  660
661   FTAKFPLYMV  FHIIDLLLCE  GISVIFNVAL  SLLKTSKDDL  LQTDFEGALK  FFRVPVPKRY  720
721   RSEENAKKLM  ELACSMKISQ  KKLKKYEKEY  HTIREQQEQQ  EAPIERYERE  NRRLQEANMR  780
781   LEQENDDLAH  ELVSSKIALR  KDLDNAEEKA  DALNKELLIT  KQKLVESEDE  KRRLEEESAQ  840
841   LKEMCRRELD  KSESEIKKNG  SIIGEYKQIC  SQLSERLEKQ  QTANRGELEK  IRMKVEGCEK  900
901   CSNLFSKEGR  LKVLSAPKEG  SEEDTDEEKE  ALKNQLREME  LELAQTKLQL  VEAECKIQDL  960
961   EHHLGLALNE  VQAAKKTWFN  RTLSSIKTVT  GAQGKESV  998
Nucleotide CDS Sequence (FASTA)
1     ATGGACCCTT  CAGTCACTGA  ACTGGTGGTT  GGACCGGATC  ATTTGGGACA  GGGTGACCAT  60
61    GGCTATCCCA  CTACAGCTGT  GCCATCACGC  TCCGGCTCTG  TGCCTCCTAA  ACTCGAGATA  120
121   GTGCTGCCCA  TTCAGGGAGC  TCAGGAGAGT  GAACTCAATG  AGAGATCTTA  CAGGGATGAG  180
181   CCCTCTGACT  TGAGTCCTGG  TACCCCTGTC  CCAGATGAGG  ACAGCGTGGT  GTTCAGTAAA  240
241   CTGACGTATT  TAGGTTGTGC  GTCAGTGAAC  GCCCCACGCA  GTGAGGTGGA  GGCCCTGCGC  300
301   ATGGTCAGCA  TCCTCCGCAG  CCAGTGCCAG  ATGCCCCTGG  ATGTCACGCT  CTCTGTACCC  360
361   GGAGTCTCAG  AGGGCACCGT  CAGACTGCTG  GACCCTCAGA  GCAGCACTGA  GATTGCCAAT  420
421   TACCCCATTT  ACAAGATCCT  CTTCTGTGTT  CGTGGTCATG  ACGGGACGCC  TGAGAGCGAC  480
481   TGCTTCGCAT  TCACTGAAAG  CCATTACAAC  ACCGAGATCT  TCCGTATCCA  CGTCTTCCGC  540
541   TGTGAGATCC  AAGAGGCGGT  CAGTCGAATA  CTCTACAGCT  TTGCCACAGC  ATTCCGCAGA  600
601   TCAGCCAATA  AAGCGCCACT  CGCGACCAAG  GCTCCGCCCC  TCACACCAGA  CAGCGACGTC  660
661   TTCACCTTTA  CCGTCAGCCT  GGAGATCAAA  GAGGATGACG  GGAAGGGCAC  GTTCAGTGCC  720
721   GTATCAAAAG  ACAAGGACAG  ACAGAGCTTC  AAACTGCGGG  CCGGCATGGA  CAAAAAAATT  780
781   GTGATCTACG  TCCAGCAAAC  GTCCAACAAA  GAGCTGGCCA  TCGAGAGGTG  TTTTGGTCTG  840
841   CTTTTGAGTC  CGGGGAAGAA  CGTGAAGAAC  AGTGATATGC  ACCTGCTCGA  CCTGGAGTCA  900
901   ATGGGCAAAA  GCTCTGATGG  GAAATCTTAC  ATCATCACAG  GGAGCTGGAA  TCCCAACACT  960
961   CCTCAGTTTC  AAGCTGTGAA  TGAGGAGACG  CCCAAAGATA  AGTTCATGTA  CATGACAACG  1020
1021  GCGGTTGACT  TGGTGATCAC  TGAGGTCGAG  GAGCCTGTGA  GGTTCCTGCT  AGAGACACGG  1080
1081  GTTCGAGTGT  GTTCACCCAA  CGAGAGGCTG  TTCTGGCCCT  TCAGCAAACG  CAGTTACACA  1140
1141  GAGACCTTCT  ATCTCAAACT  CAGACAGATG  GAGAACAAGG  AGAGGAAGAG  TAACTCGGAT  1200
1201  ACGCTGTATG  AAGTGATGAG  TTTAGAGAGC  GAGACAGAAA  GAGAAAGAAG  GAAGACCACA  1260
1261  GCGAGCCCCG  GCGTACTGTC  TTCTGGGTCC  CATGGCTCCA  CGGTGCCATC  TCCACCTGAG  1320
1321  GATGATGAGG  AAGAAGATAA  CGACGAGCCA  TTATTAAGTG  GCTCTGGAGA  CGTCTCTAAA  1380
1381  GAATGTGCCG  AAAAGATTCT  GGAAACTTGG  GGAGAACTGC  TGTCGAGATG  GCATCTGAAC  1440
1441  TTGGCAGTGC  GTCCCAAACA  GCTCCCGGCG  CTGGTGCGCA  GCGGTGTTCC  AGAAGCCTTG  1500
1501  AGAGGGGAGG  TGTGGCAGCT  ACTGGCCGGA  TGTCATAACA  ATGACCATCT  GGTGGAGGAG  1560
1561  TACCGGACTC  TCATCACTAA  GGAATCTCCA  CAGGACAGTG  CCATCACTCG  GGACATTAAC  1620
1621  CGTACGTTTC  CTGCACACGA  CTACTTCAAA  GACACAGGGG  GTGATGGGCA  GGACTCTCTC  1680
1681  TATAAGATCT  GTAAGGCGTA  TTCTGTTTAT  GATGAAGAAA  TCGGTTACTG  TCAAGGGCAG  1740
1741  TCCTTTCTTG  CTGCTGTGCT  GCTATTACAC  ATGCCAGAAG  AGCAGGCGTT  CAGCGTGCTG  1800
1801  GTCAAGATCA  TGTTTGAATA  CGGTCTCAGG  GAGCTCTTTA  AGCAGAACTT  TGAAGACCTG  1860
1861  CACTGCAAGT  TCTTCCAGCT  GGAGAGACTC  ATGCAGGAAT  GCATTCCAGA  CCTGTACACA  1920
1921  CACTTCCTGA  ACTTGGGTTT  GGAGGCGCAC  ATGTACGCCT  CCCAGTGGTT  CCTCACACTC  1980
1981  TTCACAGCCA  AATTCCCTCT  TTACATGGTC  TTTCACATCA  TAGATCTTCT  GCTGTGTGAG  2040
2041  GGCATCAGTG  TCATTTTTAA  TGTGGCTCTT  TCATTATTGA  AGACATCTAA  AGATGATCTG  2100
2101  CTGCAGACGG  ATTTTGAGGG  TGCACTGAAG  TTTTTCCGAG  TGCCTGTGCC  CAAGCGCTAT  2160
2161  CGCTCTGAGG  AAAATGCTAA  GAAGCTCATG  GAGTTAGCAT  GCAGTATGAA  GATCAGCCAG  2220
2221  AAGAAGCTGA  AGAAGTACGA  GAAGGAATAT  CACACCATTC  GCGAGCAGCA  AGAACAGCAG  2280
2281  GAGGCGCCGA  TCGAGAGATA  TGAGAGAGAA  AACCGGCGGC  TACAGGAAGC  CAACATGCGA  2340
2341  CTGGAGCAGG  AAAATGACGA  TTTGGCTCAC  GAGCTGGTCA  GCAGTAAGAT  CGCCCTGAGG  2400
2401  AAAGATCTGG  ACAACGCTGA  GGAGAAAGCA  GACGCGCTCA  ACAAAGAGCT  TCTCATCACT  2460
2461  AAACAGAAAC  TGGTGGAGTC  GGAAGATGAG  AAAAGACGAC  TGGAGGAAGA  GTCTGCACAG  2520
2521  CTGAAGGAGA  TGTGTCGGAG  AGAGCTGGAT  AAATCTGAGT  CCGAGATCAA  GAAGAACGGC  2580
2581  TCCATCATCG  GCGAATACAA  ACAGATCTGC  TCTCAGCTCA  GCGAGCGACT  GGAGAAACAG  2640
2641  CAGACGGCCA  ACAGAGGAGA  ACTAGAGAAG  ATTCGGATGA  AGGTGGAGGG  CTGTGAGAAG  2700
2701  TGCAGTAATC  TCTTCAGTAA  GGAGGGCCGT  CTGAAGGTGC  TCAGTGCTCC  AAAGGAGGGC  2760
2761  AGCGAGGAGG  ACACAGACGA  GGAGAAGGAA  GCGCTGAAGA  ACCAGCTGAG  AGAGATGGAG  2820
2821  CTGGAGCTCG  CACAGACCAA  ACTACAGCTG  GTGGAGGCAG  AGTGCAAGAT  TCAGGATCTG  2880
2881  GAGCATCATC  TGGGTCTCGC  TCTGAATGAA  GTCCAAGCGG  CCAAAAAGAC  GTGGTTCAAC  2940
2941  AGGACATTAA  GCTCCATCAA  GACTGTGACA  GGAGCTCAAG  GCAAAGAGAG  CGTGTAA  2997

▼ ANNOTATION

Disorder
IUPred2A
Interaction
MIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-2239Astyanax mexicanus90.990.01693
LLPS-Icp-1299Ictalurus punctatus89.780.01671
LLPS-Xim-0974Xiphophorus maculatus88.060.01681
LLPS-Pof-2047Poecilia formosa88.060.01683
LLPS-Scm-2474Scophthalmus maximus88.060.01677
LLPS-Leo-0349Lepisosteus oculatus88.010.01642
LLPS-Orl-2995Oryzias latipes87.480.01675
LLPS-Orn-0237Oreochromis niloticus87.480.01638
LLPS-Tar-0778Takifugu rubripes87.286e-105 335
LLPS-Gaa-0456Gasterosteus aculeatus86.710.01648
LLPS-Scf-0611Scleropages formosus86.280.01617
LLPS-Ten-2050Tetraodon nigroviridis85.390.01605
LLPS-Mum-3647Mus musculus85.180.01553
LLPS-Lac-1235Latimeria chalumnae84.820.01589
LLPS-Maf-1092Macaca fascicularis84.180.01540
LLPS-Paa-2772Papio anubis84.180.01539
LLPS-Man-2399Macaca nemestrina84.180.01541
LLPS-Mam-3993Macaca mulatta84.180.01540
LLPS-Rhb-3761Rhinopithecus bieti84.080.01538
LLPS-Chs-2211Chlorocebus sabaeus83.80.01538
LLPS-Ict-1695Ictidomys tridecemlineatus83.770.01535
LLPS-Mod-0248Monodelphis domestica83.750.01537
LLPS-Fud-1873Fukomys damarensis83.680.01544
LLPS-Myl-4119Myotis lucifugus83.670.01552
LLPS-Sah-3055Sarcophilus harrisii83.650.01538
LLPS-Pes-2411Pelodiscus sinensis83.650.01541
LLPS-Ran-1833Rattus norvegicus83.620.01549
LLPS-Nol-1264Nomascus leucogenys83.580.01544
LLPS-Sus-3525Sus scrofa83.480.01545
LLPS-Gog-0272Gorilla gorilla83.480.01544
LLPS-Hos-1917Homo sapiens83.480.01544
LLPS-Loa-4066Loxodonta africana83.280.01547
LLPS-Eqc-0369Equus caballus83.280.01541
LLPS-Cea-3214Cercocebus atys83.250.01533
LLPS-Mal-3274Mandrillus leucophaeus83.250.01532
LLPS-Fec-1128Felis catus83.180.01560
LLPS-Mea-0116Mesocricetus auratus83.170.01529
LLPS-Ova-0795Ovis aries83.170.01546
LLPS-Cap-2607Cavia porcellus83.170.01521
LLPS-Mup-4070Mustela putorius furo83.080.01534
LLPS-Otg-1433Otolemur garnettii83.080.01540
LLPS-Bot-0251Bos taurus83.070.01543
LLPS-Orc-0161Oryctolagus cuniculus83.020.01547
LLPS-Aim-2090Ailuropoda melanoleuca82.820.01533
LLPS-Anp-1919Anas platyrhynchos82.790.01538
LLPS-Caf-1172Canis familiaris82.780.01527
LLPS-Fia-0431Ficedula albicollis82.770.01543
LLPS-Tag-0970Taeniopygia guttata82.760.01543
LLPS-Dio-1798Dipodomys ordii82.680.01532
LLPS-Poa-3153Pongo abelii82.580.01508
LLPS-Gaga-0669Gallus gallus82.380.01538
LLPS-Meg-2285Meleagris gallopavo82.310.01537
LLPS-Xet-2662Xenopus tropicalis81.30.01511
LLPS-Pap-3226Pan paniscus81.20.01482
LLPS-Aon-2500Aotus nancymaae81.060.01529
LLPS-Pat-2006Pan troglodytes81.020.01508
LLPS-Caj-2228Callithrix jacchus80.970.01527
LLPS-Anc-1942Anolis carolinensis75.060.01195
LLPS-Urm-1215Ursus maritimus68.621e-106 343
LLPS-Cas-0747Carlito syrichta67.081e-88 291
LLPS-Cis-1467Ciona savignyi50.160.0 843
LLPS-Cii-0058Ciona intestinalis49.410.0 830
LLPS-Abg-1417Absidia glauca42.183e-61 229
LLPS-Cae-0707Caenorhabditis elegans40.628e-72 261
LLPS-Orm-0240Oryza meridionalis39.484e-38 151
LLPS-Drm-1891Drosophila melanogaster38.870.0 581
LLPS-Chr-0761Chlamydomonas reinhardtii38.793e-33 140
LLPS-Yal-1070Yarrowia lipolytica37.973e-43 171
LLPS-Brn-3161Brassica napus36.862e-44 177
LLPS-Pot-0944Populus trichocarpa36.753e-43 167