• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Cus-0646
Csa_4G297510

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Proteasome subunit alpha type
Gene Name: Csa_4G297510
Ensembl Gene: Csa_4G297510
Ensembl Protein: KGN54301
Organism: Cucumis sativus
Taxa ID: 3659
LLPS Type: LLPS regulator


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION


The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblKGN54301KGN54301
UniProtA0A0A0L2D7, A0A0A0L2D7_CUCSA
GeneBankCM002925KGN54301.1
RefSeqXM_004142003.2XP_004142051.2

▼ SEQUENCE


Protein Sequence (FASTA)
1     MSRRYDSRTT  IFSPEGRLYQ  VEYAMEAIGN  AGSAIGILST  DGVVLVGEKK  VTSKLLQTST  60
61    STEKMYKLDD  HVACAVAGIM  SDANILINTA  RVQAQRYTYA  YQEPMPVEQL  VQSLCDSKQG  120
121   YTQFGGLRPF  GVSFLFAGWD  KNYGFQLYMS  DPSGNYGGWK  AAAIGANNQA  AQPMLKQDYK  180
181   DDITREEAIQ  LALKVLSKTM  DSTSLTSEKL  ELAEVFLSAG  KVKYQVCSPE  SVSRLLVKSG  240
241   LTQPAAEAS  249
Nucleotide CDS Sequence (FASTA)
1     ATGTCTCGAA  GATATGATAG  CCGAACGACA  ATTTTCTCTC  CTGAAGGCCG  TCTTTACCAA  60
61    GTTGAATATG  CAATGGAGGC  AATTGGAAAT  GCAGGCTCTG  CAATTGGAAT  ATTATCTACA  120
121   GATGGGGTTG  TCTTGGTAGG  TGAAAAGAAG  GTTACATCCA  AACTCCTCCA  GACCTCAACT  180
181   TCCACTGAGA  AGATGTACAA  ACTTGATGAC  CATGTTGCAT  GTGCTGTGGC  TGGAATTATG  240
241   TCCGATGCCA  ACATATTGAT  CAACACTGCA  AGGGTTCAAG  CCCAACGATA  CACTTATGCG  300
301   TACCAAGAGC  CAATGCCTGT  TGAGCAACTG  GTTCAATCTC  TCTGCGATTC  AAAGCAAGGA  360
361   TACACCCAAT  TTGGTGGTCT  ACGGCCCTTT  GGCGTCTCTT  TTCTTTTTGC  AGGATGGGAT  420
421   AAAAACTATG  GCTTTCAACT  ATACATGAGC  GACCCAAGTG  GAAACTATGG  TGGTTGGAAG  480
481   GCTGCTGCCA  TTGGTGCCAA  CAACCAGGCA  GCACAGCCAA  TGCTTAAACA  GGATTACAAG  540
541   GACGATATCA  CTAGAGAAGA  GGCCATACAG  CTTGCACTTA  AGGTTCTTAG  CAAAACCATG  600
601   GACAGCACAA  GTCTTACATC  TGAAAAGCTC  GAATTAGCTG  AGGTTTTCCT  CTCTGCTGGA  660
661   AAGGTCAAGT  ACCAAGTTTG  CTCACCCGAG  TCTGTTAGCA  GGTTGTTGGT  GAAGTCTGGT  720
721   TTGACTCAAC  CAGCTGCTGA  GGCTTCCTAA  750

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
Hydrolase
Nucleus
Protease
Proteasome
Reference proteome
Threonine protease

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Cellular Component
Proteasome core complex, alpha-subunit complex
Molecular Function
Threonine-type endopeptidase activity
Biological Process
Ubiquitin-dependent protein catabolic process

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Coc-2327Corchorus capsularis95.453e-89 268
LLPS-Thc-1769Theobroma cacao94.01e-163 461
LLPS-Gor-0855Gossypium raimondii93.69e-163 458
LLPS-Nia-2287Nicotiana attenuata93.521e-163 461
LLPS-Prp-1992Prunus persica93.23e-163 459
LLPS-Dac-1309Daucus carota92.772e-163 460
LLPS-Viv-1351Vitis vinifera92.41e-161 455
LLPS-Sot-0861Solanum tuberosum92.317e-162 456
LLPS-Pot-0446Populus trichocarpa92.01e-160 453
LLPS-Glm-0819Glycine max92.04e-161 454
LLPS-Vir-1138Vigna radiata91.68e-161 453
LLPS-Via-0640Vigna angularis91.68e-161 453
LLPS-Hea-1333Helianthus annuus91.575e-160 454
LLPS-Sol-0850Solanum lycopersicum91.53e-160 452
LLPS-Mae-0845Manihot esculenta91.22e-157 445
LLPS-Phv-0945Phaseolus vulgaris91.22e-159 450
LLPS-Met-0113Medicago truncatula90.85e-161 454
LLPS-Bro-0718Brassica oleracea89.24e-157 444
LLPS-Arl-1082Arabidopsis lyrata88.895e-143 408
LLPS-Brr-0227Brassica rapa88.81e-156 443
LLPS-Art-1294Arabidopsis thaliana88.43e-155 439
LLPS-Amt-0158Amborella trichopoda87.652e-152 432
LLPS-Mua-1216Musa acuminata87.24e-154 437
LLPS-Hov-0584Hordeum vulgare85.466e-135 388
LLPS-Sei-0231Setaria italica85.26e-150 426
LLPS-Zem-0508Zea mays84.81e-149 425
LLPS-Sob-0822Sorghum bicolor84.43e-148 421
LLPS-Tra-1586Triticum aestivum84.07e-149 423
LLPS-Orgl-0869Oryza glumaepatula83.21e-147 420
LLPS-Lep-1414Leersia perrieri83.25e-147 418
LLPS-Orbr-0651Oryza brachyantha82.83e-145 414
LLPS-Ors-1743Oryza sativa82.86e-147 418
LLPS-Org-0946Oryza glaberrima82.86e-147 418
LLPS-Orr-1923Oryza rufipogon82.85e-147 418
LLPS-Orni-0586Oryza nivara82.86e-147 418
LLPS-Orb-1957Oryza barthii82.86e-147 418
LLPS-Ori-1276Oryza indica82.85e-147 418
LLPS-Brd-1252Brachypodium distachyon82.88e-147 418
LLPS-Php-0119Physcomitrella patens82.43e-144 411
LLPS-Sem-1306Selaginella moellendorffii79.926e-135 388
LLPS-Miv-0589Microbotryum violaceum79.491e-1372.8
LLPS-Orp-0460Oryza punctata79.22e-135 388
LLPS-Brn-1956Brassica napus72.45e-114 333
LLPS-Nol-1766Nomascus leucogenys68.756e-79 244
LLPS-Abg-0237Absidia glauca68.642e-110 325
LLPS-Gas-0141Galdieria sulphuraria67.746e-115 337
LLPS-Chr-0285Chlamydomonas reinhardtii66.394e-107 317
LLPS-Fud-0889Fukomys damarensis65.712e-93 281
LLPS-Kop-0118Komagataella pastoris65.166e-107 317
LLPS-Beb-0852Beauveria bassiana64.342e-104 310
LLPS-Chc-0844Chondrus crispus64.051e-109 323
LLPS-Trr-0839Trichoderma reesei63.931e-103 308
LLPS-Fus-0556Fusarium solani63.939e-104 308
LLPS-Ast-0842Aspergillus terreus63.935e-102 304
LLPS-Trv-0475Trichoderma virens63.931e-103 308
LLPS-Fuo-1279Fusarium oxysporum63.938e-104 308
LLPS-Mao-0969Magnaporthe oryzae63.933e-103 307
LLPS-Fuv-1340Fusarium verticillioides63.938e-104 308
LLPS-Blg-1063Blumeria graminis63.712e-100 300
LLPS-Ved-0582Verticillium dahliae63.521e-102 305
LLPS-Asf-0704Aspergillus flavus63.523e-101 302
LLPS-Lem-1351Leptosphaeria maculans63.522e-102 305
LLPS-Aso-0671Aspergillus oryzae63.528e-101 301
LLPS-Nef-1206Neosartorya fischeri63.117e-101 301
LLPS-Asfu-0719Aspergillus fumigatus63.117e-101 301
LLPS-Cogr-0450Colletotrichum graminicola63.111e-101 303
LLPS-Pytr-1171Pyrenophora triticirepentis63.111e-101 303
LLPS-Asn-0159Aspergillus nidulans63.113e-101 302
LLPS-Asni-1118Aspergillus niger63.113e-101 302
LLPS-Asc-0935Aspergillus clavatus63.118e-101 301
LLPS-Nec-0366Neurospora crassa63.111e-102 305
LLPS-Pyt-0078Pyrenophora teres63.111e-101 303
LLPS-Cog-0981Colletotrichum gloeosporioides62.74e-101 301
LLPS-Coo-1213Colletotrichum orbiculare62.78e-101 301
LLPS-Phn-0671Phaeosphaeria nodorum62.551e-101 303
LLPS-Ten-2933Tetraodon nigroviridis62.451e-98 296
LLPS-Tar-2302Takifugu rubripes62.452e-98 295
LLPS-Yal-0183Yarrowia lipolytica62.248e-99 296
LLPS-Zyt-0064Zymoseptoria tritici62.12e-102 305
LLPS-Tum-0112Tuber melanosporum62.12e-102 305
LLPS-Spr-0216Sporisorium reilianum62.042e-100 300
LLPS-Orn-1231Oreochromis niloticus62.035e-98 294
LLPS-Dar-1757Danio rerio62.034e-98 294
LLPS-Gaa-1707Gasterosteus aculeatus61.922e-98 295
LLPS-Usm-1414Ustilago maydis61.854e-102 305
LLPS-Otg-1060Otolemur garnettii61.61e-97 293
LLPS-Orc-1167Oryctolagus cuniculus61.61e-97 293
LLPS-Rhb-2530Rhinopithecus bieti61.61e-97 293
LLPS-Hos-1364Homo sapiens61.61e-97 293
LLPS-Pap-0488Pan paniscus61.61e-97 293
LLPS-Pof-0236Poecilia formosa61.61e-97 293
LLPS-Pat-2635Pan troglodytes61.61e-97 293
LLPS-Fec-0075Felis catus61.61e-97 293
LLPS-Mod-2278Monodelphis domestica61.63e-97 292
LLPS-Scm-0995Scophthalmus maximus61.67e-98 293
LLPS-Cas-1952Carlito syrichta61.61e-97 293
LLPS-Gaga-1298Gallus gallus61.62e-97 293
LLPS-Ict-1296Ictidomys tridecemlineatus61.61e-97 293
LLPS-Poa-1694Pongo abelii61.61e-97 293
LLPS-Cap-1105Cavia porcellus61.61e-97 293
LLPS-Mam-1162Macaca mulatta61.61e-97 293
LLPS-Gog-3200Gorilla gorilla61.61e-97 293
LLPS-Caj-2060Callithrix jacchus61.61e-97 293
LLPS-Mum-4187Mus musculus61.61e-97 293
LLPS-Maf-2087Macaca fascicularis61.61e-97 293
LLPS-Mea-1739Mesocricetus auratus61.61e-97 293
LLPS-Ora-1694Ornithorhynchus anatinus61.63e-97 292
LLPS-Chs-0672Chlorocebus sabaeus61.61e-97 293
LLPS-Orl-0490Oryzias latipes61.64e-97 292
LLPS-Sus-0474Sus scrofa61.61e-97 293
LLPS-Ran-2030Rattus norvegicus61.62e-97 293
LLPS-Mal-0365Mandrillus leucophaeus61.61e-97 293
LLPS-Paa-2115Papio anubis61.61e-97 293
LLPS-Ova-3244Ovis aries61.61e-97 293
LLPS-Mup-1082Mustela putorius furo61.67e-98 294
LLPS-Dio-2168Dipodomys ordii61.61e-97 293
LLPS-Bot-0555Bos taurus61.61e-97 293
LLPS-Leo-1136Lepisosteus oculatus61.512e-98 295
LLPS-Man-1824Macaca nemestrina61.446e-96 290
LLPS-Loa-0618Loxodonta africana61.441e-96 291
LLPS-Anp-1420Anas platyrhynchos61.441e-96 291
LLPS-Tag-2398Taeniopygia guttata61.441e-96 291
LLPS-Eqc-0502Equus caballus61.441e-96 291
LLPS-Cea-1517Cercocebus atys61.447e-96 290
LLPS-Sah-1086Sarcophilus harrisii61.442e-96 290
LLPS-Myl-0312Myotis lucifugus61.442e-96 290
LLPS-Aim-0203Ailuropoda melanoleuca61.448e-97 291
LLPS-Scf-1066Scleropages formosus61.446e-97 291
LLPS-Fia-0333Ficedula albicollis61.348e-96 288
LLPS-Dos-1163Dothistroma septosporum61.297e-101 301
LLPS-Asm-0511Astyanax mexicanus61.182e-97 292
LLPS-Icp-0152Ictalurus punctatus61.182e-97 292
LLPS-Sac-0596Saccharomyces cerevisiae61.071e-100 300
LLPS-Meg-2227Meleagris gallopavo61.023e-96 290
LLPS-Cis-0463Ciona savignyi61.023e-95 287
LLPS-Gag-0496Gaeumannomyces graminis60.876e-90 273
LLPS-Lac-1085Latimeria chalumnae60.55e-95 287
LLPS-Asg-0970Ashbya gossypii60.494e-98 294
LLPS-Scj-0257Schizosaccharomyces japonicus60.341e-97 293
LLPS-Xet-1480Xenopus tropicalis60.01e-62 201
LLPS-Cae-1023Caenorhabditis elegans59.756e-88 268
LLPS-Cym-0377Cyanidioschyzon merolae59.641e-87 267
LLPS-Osl-1150Ostreococcus lucimarinus59.432e-81 251
LLPS-Crn-0783Cryptococcus neoformans59.44e-89 272
LLPS-Aon-0361Aotus nancymaae58.185e-76 237
LLPS-Urm-2410Ursus maritimus57.966e-85 262
LLPS-Ere-0047Erinaceus europaeus57.922e-82 254
LLPS-Xim-0597Xiphophorus maculatus57.281e-77 241
LLPS-Scp-1562Schizosaccharomyces pombe57.141e-92 280
LLPS-Drm-0728Drosophila melanogaster56.612e-88 270
LLPS-Scc-0834Schizosaccharomyces cryophilus56.572e-94 285
LLPS-Pes-0682Pelodiscus sinensis56.549e-85 260
LLPS-Mel-0081Melampsora laricipopulina50.02e-82 255
LLPS-Put-0882Puccinia triticina48.12e-79 248
LLPS-Pug-1267Puccinia graminis46.677e-77 243
LLPS-Caf-4213Canis familiaris40.431e-46 162
LLPS-Tru-0613Triticum urartu40.421e-46 162