• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Coo-1049
Cob_13236

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tubulin alpha chain
Gene Name: Cob_13236
Ensembl Gene: Cob_13236
Ensembl Protein: ENH77457
Organism: Colletotrichum orbiculare
Taxa ID: 1213857
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Microtubule, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENH77457ENH77457
UniProtN4V1I5, N4V1I5_COLOR
GeneBankKB726084ENH77457.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MREVISINVG  QAGCQIANSC  WELYCLEHGI  QPDGYLTEER  KQADPDHGFS  TFFSETGQGK  60
61    YVPRAIYCDL  EPNVVDEVRT  GPYRGLFHPE  HMITGKEDAS  NNYARGHYTV  GKELIDQVLD  120
121   KVRRVADNCV  GLQGFLVFHS  FGGGTGSGFG  ALLMERLSVD  YGKKSKLEFC  VYPAPQTATS  180
181   VVEPYNSILT  THTTLEHSDC  SFMVDNEAIY  DICRRNLGLE  RPNYENLNRL  IAQVVSSITA  240
241   SLRFDGSLNV  DLNEFQTNLV  PYPRIHFPLV  AYAPMISAAK  AAHEANSVQE  MTMSCFEPNN  300
301   QMVKCDPRHG  KYMATCLLYR  GDVVPNDAHA  AVATLKTKRT  IQFVDWCPTG  FKLGICYQAP  360
361   QMVPNGDLAK  VSRAVCMLSN  TTAIAEAWSA  LSTKFDLMYS  KRAFVHWYVG  EGMEEGEFSE  420
421   AREDLAALER  DYEEVAADSL  EGEEGLEAEY  450
Nucleotide CDS Sequence (FASTA)
1     ATGCGCGAGG  TCATCAGCAT  CAACGTCGGT  CAGGCTGGTT  GCCAGATTGC  CAACTCTTGC  60
61    TGGGAGCTTT  ACTGCCTAGA  GCACGGTATC  CAACCCGATG  GATACTTGAC  TGAGGAGCGC  120
121   AAGCAAGCCG  ATCCCGATCA  CGGCTTCAGC  ACCTTCTTCT  CCGAGACTGG  CCAGGGCAAG  180
181   TACGTCCCCC  GTGCCATCTA  CTGCGACCTC  GAGCCCAACG  TCGTCGATGA  GGTCCGCACC  240
241   GGTCCCTACC  GCGGTCTCTT  TCACCCTGAG  CATATGATTA  CCGGCAAGGA  GGATGCCTCC  300
301   AACAACTACG  CTCGTGGCCA  CTACACCGTA  GGCAAGGAGC  TGATCGACCA  GGTCCTCGAC  360
361   AAGGTTCGTC  GCGTTGCGGA  CAATTGCGTT  GGCCTCCAGG  GTTTCCTCGT  CTTCCACTCC  420
421   TTTGGTGGAG  GTACTGGCTC  GGGTTTCGGC  GCTCTCTTGA  TGGAACGCCT  CTCCGTCGAC  480
481   TACGGCAAGA  AGAGCAAGCT  CGAGTTTTGC  GTTTACCCCG  CCCCTCAGAC  TGCTACCTCC  540
541   GTTGTCGAGC  CGTACAACTC  TATTCTCACC  ACCCACACCA  CCCTTGAGCA  CTCTGACTGC  600
601   TCCTTCATGG  TCGACAACGA  GGCCATCTAC  GACATATGCC  GCCGTAACCT  TGGTCTTGAG  660
661   CGTCCCAACT  ACGAGAATCT  GAACCGGTTG  ATTGCGCAGG  TTGTTTCGTC  CATCACCGCC  720
721   TCTCTTCGCT  TTGACGGCTC  TCTCAATGTC  GACCTGAACG  AATTCCAGAC  GAACCTGGTC  780
781   CCTTACCCTC  GTATTCATTT  CCCCTTAGTT  GCCTACGCTC  CTATGATCTC  TGCCGCCAAG  840
841   GCCGCTCACG  AGGCAAATTC  CGTGCAGGAG  ATGACCATGT  CCTGCTTCGA  GCCGAACAAC  900
901   CAGATGGTCA  AGTGCGACCC  CCGCCACGGC  AAATACATGG  CCACCTGCCT  GCTGTACCGC  960
961   GGAGACGTCG  TTCCCAACGA  CGCCCACGCT  GCTGTGGCGA  CATTGAAGAC  GAAGCGTACC  1020
1021  ATCCAGTTTG  TCGACTGGTG  TCCTACCGGT  TTCAAGCTCG  GTATCTGCTA  CCAGGCTCCT  1080
1081  CAGATGGTTC  CCAACGGTGA  TCTCGCGAAG  GTCAGCCGCG  CTGTCTGCAT  GCTCTCCAAT  1140
1141  ACCACCGCCA  TCGCCGAGGC  CTGGTCCGCT  CTGTCGACTA  AATTTGATCT  CATGTACTCG  1200
1201  AAGCGTGCCT  TCGTTCACTG  GTACGTTGGT  GAGGGTATGG  AGGAGGGCGA  GTTCTCCGAG  1260
1261  GCTCGTGAGG  ATCTTGCTGC  CCTGGAGCGT  GACTACGAGG  AGGTTGCAGC  CGACTCTCTC  1320
1321  GAGGGAGAGG  AGGGGCTTGA  GGCTGAGTAC  TAA  1353

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Microtubule
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Structural constituent of cytoskeleton
Biological Process
Microtubule-based process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cog-0528Colletotrichum gloeosporioides100.00.0 899
LLPS-Cogr-0248Colletotrichum graminicola97.720.0 869
LLPS-Fus-1156Fusarium solani96.440.0 880
LLPS-Fuv-0423Fusarium verticillioides96.00.0 877
LLPS-Fuo-1566Fusarium oxysporum96.00.0 877
LLPS-Ved-0684Verticillium dahliae95.780.0 882
LLPS-Trv-1202Trichoderma virens95.560.0 874
LLPS-Nec-0507Neurospora crassa95.330.0 880
LLPS-Trr-1592Trichoderma reesei95.330.0 873
LLPS-Beb-0573Beauveria bassiana93.330.0 855
LLPS-Phn-0573Phaeosphaeria nodorum92.890.0 856
LLPS-Lem-1244Leptosphaeria maculans92.440.0 852
LLPS-Asn-0182Aspergillus nidulans92.270.0 840
LLPS-Pyt-1007Pyrenophora teres91.780.0 848
LLPS-Pytr-0618Pyrenophora triticirepentis91.780.0 848
LLPS-Tum-1602Tuber melanosporum89.780.0 827
LLPS-Cae-0367Caenorhabditis elegans80.640.0 736
LLPS-Cis-1874Ciona savignyi79.730.0 734
LLPS-Gaga-0784Gallus gallus79.730.0 741
LLPS-Scj-0016Schizosaccharomyces japonicus79.640.0 738
LLPS-Mod-3334Monodelphis domestica79.550.0 732
LLPS-Fud-2337Fukomys damarensis79.50.0 738
LLPS-Sah-0275Sarcophilus harrisii79.50.0 730
LLPS-Drm-0758Drosophila melanogaster79.50.0 731
LLPS-Fia-2663Ficedula albicollis79.50.0 739
LLPS-Dar-1000Danio rerio79.50.0 738
LLPS-Caj-2133Callithrix jacchus79.450.0 723
LLPS-Gog-1557Gorilla gorilla79.320.0 731
LLPS-Icp-1801Ictalurus punctatus79.320.0 733
LLPS-Asm-0148Astyanax mexicanus79.320.0 732
LLPS-Chs-1766Chlorocebus sabaeus79.320.0 731
LLPS-Mum-2981Mus musculus79.320.0 731
LLPS-Sus-3651Sus scrofa79.320.0 731
LLPS-Ran-1850Rattus norvegicus79.320.0 731
LLPS-Bot-1689Bos taurus79.320.0 731
LLPS-Scf-2328Scleropages formosus79.320.0 732
LLPS-Dio-2079Dipodomys ordii79.320.0 731
LLPS-Orc-2690Oryctolagus cuniculus79.320.0 731
LLPS-Pat-0032Pan troglodytes79.320.0 731
LLPS-Hos-0454Homo sapiens79.320.0 731
LLPS-Anc-2036Anolis carolinensis79.320.0 731
LLPS-Poa-2507Pongo abelii79.320.0 731
LLPS-Mam-0274Macaca mulatta79.320.0 731
LLPS-Orl-2503Oryzias latipes79.280.0 735
LLPS-Aon-0811Aotus nancymaae79.270.0 729
LLPS-Paa-3203Papio anubis79.270.0 729
LLPS-Lac-1000Latimeria chalumnae79.270.0 729
LLPS-Meg-2759Meleagris gallopavo79.270.0 729
LLPS-Fec-2940Felis catus79.230.0 736
LLPS-Mea-1952Mesocricetus auratus79.090.0 729
LLPS-Maf-0074Macaca fascicularis79.090.0 730
LLPS-Cii-0592Ciona intestinalis79.090.0 732
LLPS-Cea-1318Cercocebus atys79.090.0 730
LLPS-Myl-1786Myotis lucifugus79.090.0 724
LLPS-Ova-0174Ovis aries79.090.0 730
LLPS-Mup-0654Mustela putorius furo79.090.0 730
LLPS-Mal-0207Mandrillus leucophaeus79.090.0 730
LLPS-Tar-1284Takifugu rubripes79.090.0 729
LLPS-Xim-1672Xiphophorus maculatus79.090.0 731
LLPS-Scm-0904Scophthalmus maximus79.090.0 731
LLPS-Pap-4472Pan paniscus79.090.0 730
LLPS-Urm-3000Ursus maritimus79.090.0 730
LLPS-Pof-3465Poecilia formosa79.090.0 731
LLPS-Man-3545Macaca nemestrina79.090.0 730
LLPS-Ict-2143Ictidomys tridecemlineatus79.090.0 729
LLPS-Nol-2673Nomascus leucogenys79.090.0 730
LLPS-Eqc-0069Equus caballus79.090.0 730
LLPS-Cap-3401Cavia porcellus79.090.0 730
LLPS-Caf-1913Canis familiaris79.090.0 730
LLPS-Ora-0959Ornithorhynchus anatinus79.040.0 728
LLPS-Leo-1381Lepisosteus oculatus79.040.0 731
LLPS-Ere-0436Erinaceus europaeus79.040.0 728
LLPS-Aim-0544Ailuropoda melanoleuca79.040.0 728
LLPS-Tut-0018Tursiops truncatus79.040.0 728
LLPS-Loa-3072Loxodonta africana79.040.0 728
LLPS-Cas-1839Carlito syrichta79.040.0 728
LLPS-Xet-0291Xenopus tropicalis78.910.0 731
LLPS-Pes-3386Pelodiscus sinensis78.860.0 723
LLPS-Otg-3152Otolemur garnettii78.590.0 726
LLPS-Gaa-2011Gasterosteus aculeatus78.410.0 726
LLPS-Anp-1080Anas platyrhynchos78.40.0 734
LLPS-Ten-2970Tetraodon nigroviridis78.40.0 735
LLPS-Scp-0862Schizosaccharomyces pombe78.30.0 727
LLPS-Orn-2346Oreochromis niloticus77.950.0 721
LLPS-Mel-1541Melampsora laricipopulina77.70.0 720
LLPS-Tag-0253Taeniopygia guttata77.650.0 726