LLPS-Cog-0544
CGGC5_2178
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | 3-isopropylmalate dehydratase; Alpha-IPM isomerase; Isopropylmalate isomerase |
| Gene Name: | CGGC5_2178 |
| Ensembl Gene: | CGGC5_2178 |
| Ensembl Protein: | ELA24403 |
| Organism: | Colletotrichum gloeosporioides |
| Taxa ID: | 1213859 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ELA24403 | ELA24403 |
| UniProt | L2FFA1, L2FFA1_COLFN | |
| GeneBank | KB021269 | ELA24403.1 |
| RefSeq | XM_007286466.1 | XP_007286528.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPVAEGTPQT LYDKVLQAHV VDEKLDGTVL LYIDRHLVHE VTSPQAFEGL KNAGRKVRRP 60 61 DCTLATTDHN VPTSSRKGMK DIGSFIAEDD SRVQCVTLEE NVKDFGLTYF GLGDKRQGIV 120 121 HVIGPEQGFT LPGTTVVCGD SHTSTHGAFG ALAFGIGTSE VEHVLATQCL ITKRSKNMRI 180 181 QVDGELAPGV SSKDVVLHAI GKIGTAGGTG AVIEFCGSVI RSLSIEARMS ICNMSIEGGA 240 241 RAGMVAPDEV TFEYLKNRPL APKYNSDEWH RATKYWKSLQ SDPDAKYDID VFIDAKDIIP 300 301 TITWGTSPED VVPITGTVPD PETFPTEAKK AAGRRMLEYM GLTAGTPLEE IPIDKVFIGS 360 361 CTNSRIEDLR AAAHVVKGKK IAPNVKRAMV VPGSGLVKTQ AESEGLDKIF IDAGFEWREA 420 421 GCSMCLGMNP DILAPKERCA STSNRNFEGR QGALSRTHLM SPVMAAAAGI VGKLADVRKL 480 481 SQYKASPHIE AAITPIEPHV DERVEESSEE KEAIADQPED NQPHTNTSAS ASGSSTGLPK 540 541 FTNLKGIAAP LEKSNVDTDA IIPKQFLKTI KRTGLGKALF YELRFNSDGS ENPNFVLNND 600 601 PYRAAKILVV TGPNFGCGSS REHAPWALND FGIRCVLAPS FADIFFNNTF KNGMLPIVIP 660 661 DQAVLEKIAD EARAGKEIEI DLPNQLIKDA SGNTLASFDV EEFRKHCLIN GLDDIGLTMQ 720 721 MNDKITDYER RMSQLTPWLD GTSYLKRDPK TGQLLAKAVP VPKTNRGETK TEPLEW 776 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | 3-isopropylmalate dehydratase complex | |
Molecular Function | 3-isopropylmalate dehydratase activity | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Biological Process | Leucine biosynthetic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Coo-1460 | Colletotrichum orbiculare | 93.19 | 0.0 | 1460 |
| LLPS-Cogr-1102 | Colletotrichum graminicola | 89.7 | 0.0 | 1403 |
| LLPS-Ved-0538 | Verticillium dahliae | 85.07 | 0.0 | 1337 |
| LLPS-Mao-0737 | Magnaporthe oryzae | 84.21 | 0.0 | 1292 |
| LLPS-Gag-1349 | Gaeumannomyces graminis | 84.08 | 0.0 | 1304 |
| LLPS-Fus-0295 | Fusarium solani | 83.53 | 0.0 | 1300 |
| LLPS-Fuo-0634 | Fusarium oxysporum | 83.27 | 0.0 | 1300 |
| LLPS-Fuv-0579 | Fusarium verticillioides | 83.14 | 0.0 | 1299 |
| LLPS-Map-0861 | Magnaporthe poae | 82.82 | 0.0 | 1292 |
| LLPS-Trr-1227 | Trichoderma reesei | 82.44 | 0.0 | 1286 |
| LLPS-Nec-1554 | Neurospora crassa | 82.2 | 0.0 | 1311 |
| LLPS-Beb-0749 | Beauveria bassiana | 81.16 | 0.0 | 1286 |
| LLPS-Trv-1601 | Trichoderma virens | 77.44 | 0.0 | 1214 |
| LLPS-Asn-1545 | Aspergillus nidulans | 75.77 | 0.0 | 1177 |
| LLPS-Asf-1015 | Aspergillus flavus | 74.87 | 0.0 | 1168 |
| LLPS-Aso-0851 | Aspergillus oryzae | 74.87 | 0.0 | 1168 |
| LLPS-Asfu-0483 | Aspergillus fumigatus | 74.07 | 0.0 | 1152 |
| LLPS-Asni-0897 | Aspergillus niger | 74.01 | 0.0 | 1140 |
| LLPS-Ast-1303 | Aspergillus terreus | 73.69 | 0.0 | 1157 |
| LLPS-Blg-0939 | Blumeria graminis | 73.45 | 0.0 | 1157 |
| LLPS-Nef-0695 | Neosartorya fischeri | 73.44 | 0.0 | 1121 |
| LLPS-Asc-1408 | Aspergillus clavatus | 73.19 | 0.0 | 1139 |
| LLPS-Zyt-0949 | Zymoseptoria tritici | 72.24 | 0.0 | 1128 |
| LLPS-Dos-1391 | Dothistroma septosporum | 70.69 | 0.0 | 1113 |
| LLPS-Pytr-1639 | Pyrenophora triticirepentis | 70.5 | 0.0 | 1095 |
| LLPS-Pyt-0009 | Pyrenophora teres | 70.11 | 0.0 | 1095 |
| LLPS-Lem-0873 | Leptosphaeria maculans | 69.96 | 0.0 | 1071 |
| LLPS-Phn-1587 | Phaeosphaeria nodorum | 69.73 | 0.0 | 1092 |
| LLPS-Tum-0833 | Tuber melanosporum | 68.62 | 0.0 | 1055 |
| LLPS-Abg-0361 | Absidia glauca | 64.82 | 0.0 | 974 |
| LLPS-Scj-1344 | Schizosaccharomyces japonicus | 64.39 | 0.0 | 926 |
| LLPS-Yal-0785 | Yarrowia lipolytica | 63.87 | 0.0 | 947 |
| LLPS-Mel-1359 | Melampsora laricipopulina | 63.78 | 0.0 | 902 |
| LLPS-Miv-1090 | Microbotryum violaceum | 63.67 | 0.0 | 921 |
| LLPS-Spr-0748 | Sporisorium reilianum | 63.55 | 0.0 | 918 |
| LLPS-Usm-1170 | Ustilago maydis | 63.46 | 0.0 | 938 |
| LLPS-Scp-1344 | Schizosaccharomyces pombe | 63.36 | 0.0 | 914 |
| LLPS-Asg-0115 | Ashbya gossypii | 63.26 | 0.0 | 910 |
| LLPS-Ori-1394 | Oryza indica | 63.24 | 0.0 | 558 |
| LLPS-Crn-0038 | Cryptococcus neoformans | 63.06 | 0.0 | 936 |
| LLPS-Scc-1642 | Schizosaccharomyces cryophilus | 62.88 | 0.0 | 922 |
| LLPS-Sac-0122 | Saccharomyces cerevisiae | 62.7 | 0.0 | 905 |
| LLPS-Pug-1401 | Puccinia graminis | 61.84 | 0.0 | 879 |
| LLPS-Kop-1463 | Komagataella pastoris | 61.17 | 0.0 | 905 |
| LLPS-Put-0680 | Puccinia triticina | 60.46 | 0.0 | 874 |
| LLPS-Brr-1526 | Brassica rapa | 30.77 | 2e-47 | 180 |
| LLPS-Bro-2752 | Brassica oleracea | 30.77 | 1e-47 | 181 |
| LLPS-Brn-3174 | Brassica napus | 30.77 | 3e-47 | 179 |
| LLPS-Arl-2081 | Arabidopsis lyrata | 30.46 | 1e-47 | 181 |
| LLPS-Tru-0554 | Triticum urartu | 30.06 | 1e-30 | 130 |
| LLPS-Art-1182 | Arabidopsis thaliana | 29.94 | 1e-47 | 181 |
| LLPS-Prp-0825 | Prunus persica | 29.77 | 3e-44 | 171 |
| LLPS-Zem-0159 | Zea mays | 29.68 | 9e-43 | 167 |
| LLPS-Pot-2603 | Populus trichocarpa | 29.62 | 6e-42 | 164 |
| LLPS-Gor-0374 | Gossypium raimondii | 29.54 | 1e-44 | 172 |
| LLPS-Sob-1206 | Sorghum bicolor | 29.29 | 5e-42 | 164 |
| LLPS-Sei-0995 | Setaria italica | 29.29 | 6e-42 | 164 |
| LLPS-Thc-1246 | Theobroma cacao | 29.22 | 1e-41 | 164 |
| LLPS-Nia-2494 | Nicotiana attenuata | 29.2 | 2e-43 | 169 |
| LLPS-Sem-1251 | Selaginella moellendorffii | 29.12 | 1e-41 | 163 |
| LLPS-Ors-2415 | Oryza sativa | 29.08 | 4e-41 | 162 |
| LLPS-Orb-1196 | Oryza barthii | 29.08 | 1e-40 | 160 |
| LLPS-Mae-1995 | Manihot esculenta | 29.07 | 1e-22 | 107 |
| LLPS-Phv-0617 | Phaseolus vulgaris | 29.0 | 2e-43 | 169 |
| LLPS-Cus-2395 | Cucumis sativus | 28.99 | 2e-44 | 172 |
| LLPS-Coc-2240 | Corchorus capsularis | 28.94 | 6e-43 | 166 |
| LLPS-Tra-2843 | Triticum aestivum | 28.92 | 8e-43 | 167 |
| LLPS-Orp-0180 | Oryza punctata | 28.87 | 1e-40 | 161 |
| LLPS-Org-2265 | Oryza glaberrima | 28.87 | 7e-41 | 161 |
| LLPS-Orm-1649 | Oryza meridionalis | 28.87 | 6e-41 | 161 |
| LLPS-Orr-1014 | Oryza rufipogon | 28.87 | 3e-41 | 162 |
| LLPS-Orni-2408 | Oryza nivara | 28.87 | 2e-40 | 161 |
| LLPS-Orgl-1230 | Oryza glumaepatula | 28.87 | 3e-41 | 162 |
| LLPS-Glm-2229 | Glycine max | 28.86 | 3e-42 | 165 |
| LLPS-Sol-0649 | Solanum lycopersicum | 28.81 | 1e-42 | 166 |
| LLPS-Sot-1038 | Solanum tuberosum | 28.78 | 4e-43 | 168 |
| LLPS-Chc-0049 | Chondrus crispus | 28.77 | 3e-44 | 171 |
| LLPS-Via-0781 | Vigna angularis | 28.69 | 1e-39 | 157 |
| LLPS-Met-2622 | Medicago truncatula | 28.6 | 2e-42 | 166 |
| LLPS-Hea-1867 | Helianthus annuus | 28.48 | 4e-41 | 162 |
| LLPS-Amt-0109 | Amborella trichopoda | 28.46 | 2e-39 | 157 |
| LLPS-Mua-1458 | Musa acuminata | 28.44 | 1e-33 | 139 |
| LLPS-Dac-2136 | Daucus carota | 28.21 | 8e-23 | 108 |
| LLPS-Brd-0184 | Brachypodium distachyon | 28.17 | 4e-41 | 162 |
| LLPS-Viv-0229 | Vitis vinifera | 28.01 | 9e-41 | 161 |
| LLPS-Cym-0885 | Cyanidioschyzon merolae | 27.89 | 2e-41 | 163 |
| LLPS-Php-2405 | Physcomitrella patens | 27.85 | 7e-35 | 144 |
| LLPS-Chr-1376 | Chlamydomonas reinhardtii | 27.71 | 1e-38 | 155 |
| LLPS-Gas-0645 | Galdieria sulphuraria | 27.7 | 9e-36 | 148 |
| LLPS-Hov-1815 | Hordeum vulgare | 27.41 | 1e-19 | 98.2 |
| LLPS-Vir-1013 | Vigna radiata | 27.08 | 1e-30 | 131 |
| LLPS-Lep-1835 | Leersia perrieri | 26.93 | 2e-32 | 136 |
| LLPS-Orbr-1231 | Oryza brachyantha | 26.7 | 7e-20 | 99.4 |
| LLPS-Chs-1421 | Chlorocebus sabaeus | 26.67 | 8e-19 | 95.9 |
| LLPS-Aon-1158 | Aotus nancymaae | 25.51 | 1e-18 | 95.1 |
| LLPS-Scs-0810 | Sclerotinia sclerotiorum | 25.07 | 1e-41 | 167 |