• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cis-1723

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Glutathione synthetase
Ensembl Gene: ENSCSAVG00000008980.1
Ensembl Protein: ENSCSAVP00000015298.1
Organism: Ciona savignyi
Taxa ID: 51511
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     HASFTLFPSI  FPKSAYDLAW  NVQNDMHSLM  HKVSKDAQFL  EDVLKSTIAV  DDFVKNLFEI  60
61    YKLSCNCEMI  QKRAIGVFRS  DYMLQTQTND  VGLPKQIEVN  TMASSLMGIG  TNKLLDLHKF  120
121   NLLHMGGGSM  SSENNLPRNN  VLDSVAETFV  KGWNMYGNPN  AVFVFMLNQN  ERNVFDQRAI  180
181   EHAMYKIDPA  IKVRRKVFNT  CAATTRVDAD  GKLFIDNEEV  AVVYYRTGYM  PGHYPTKKNW  240
241   EARKMIELST  AVKSPSVAQQ  LVGSKKIQQV  LAQPGVLEHF  IDDKNVIKNL  RAVFAGLYSL  300
301   EMNSAGDGAV  KLALERPENF  VLKPQREGGG  NNLYGADLVF  QLNNVGGDER  RCAYILMEKI  360
361   QPPVQDNYIV  HNHEYNPAKT  VSELGIFGVF  LTDGDKMINS  CTVGHLLRSK  SNEHDDGGVG  420
421   AGVAVLDSPF  LV  432
Nucleotide CDS Sequence (FASTA)
1     CATGCGTCAT  TTACATTGTT  CCCCTCTATA  TTTCCTAAAA  GTGCATATGA  TCTTGCATGG  60
61    AATGTTCAAA  ATGACATGCA  TTCATTAATG  CATAAAGTGA  GCAAAGATGC  TCAGTTTTTG  120
121   GAGGATGTTC  TCAAAAGTAC  AATTGCAGTA  GATGACTTTG  TGAAAAACCT  TTTCGAGATT  180
181   TACAAGCTAT  CGTGCAACTG  TGAAATGATT  CAGAAAAGGG  CAATTGGTGT  TTTCCGATCT  240
241   GATTATATGC  TTCAGACACA  AACAAATGAT  GTGGGCTTGC  CTAAGCAGAT  TGAAGTAAAT  300
301   ACAATGGCAT  CATCTTTAAT  GGGTATTGGA  ACAAACAAGC  TTTTAGATCT  TCACAAATTT  360
361   AACTTACTGC  ATATGGGAGG  CGGTTCTATG  AGTTCGGAAA  ACAATTTGCC  GCGTAACAAT  420
421   GTTTTAGACA  GTGTGGCAGA  AACATTTGTT  AAAGGGTGGA  ATATGTATGG  AAATCCTAAT  480
481   GCAGTGTTTG  TGTTTATGCT  CAACCAAAAT  GAACGTAATG  TGTTTGATCA  ACGTGCCATT  540
541   GAGCATGCTA  TGTATAAGAT  CGATCCTGCT  ATAAAAGTAA  GAAGAAAGGT  CTTCAATACT  600
601   TGTGCAGCAA  CAACCCGCGT  TGATGCAGAT  GGAAAACTTT  TCATAGATAA  TGAAGAAGTG  660
661   GCTGTTGTGT  ATTACAGAAC  AGGGTATATG  CCCGGGCACT  ATCCAACAAA  AAAGAATTGG  720
721   GAAGCAAGAA  AAATGATTGA  GCTGAGTACT  GCTGTTAAAT  CGCCCAGTGT  TGCACAACAG  780
781   CTTGTTGGTT  CTAAAAAAAT  TCAACAAGTC  TTAGCCCAAC  CTGGAGTTCT  AGAACATTTT  840
841   ATTGATGACA  AGAATGTTAT  CAAAAATCTT  CGTGCCGTTT  TCGCAGGTTT  ATACTCACTG  900
901   GAAATGAATA  GTGCGGGTGA  TGGTGCAGTA  AAACTTGCTC  TGGAGCGACC  GGAAAATTTT  960
961   GTTCTTAAAC  CTCAAAGGGA  AGGTGGAGGA  AACAACTTAT  ATGGAGCTGA  TCTTGTCTTT  1020
1021  CAACTTAACA  ATGTCGGAGG  TGACGAAAGA  AGATGTGCTT  ATATTCTCAT  GGAGAAAATT  1080
1081  CAACCCCCAG  TTCAAGATAA  TTACATTGTT  CATAATCACG  AATACAACCC  TGCAAAAACT  1140
1141  GTCAGCGAAC  TTGGCATATT  TGGAGTATTT  TTGACAGACG  GTGATAAAAT  GATTAACAGC  1200
1201  TGCACTGTAG  GTCACTTACT  ACGTTCAAAA  TCCAATGAAC  ATGATGATGG  TGGTGTGGGT  1260
1261  GCAGGTGTAG  CCGTTTTGGA  TTCCCCATTT  CTAGTATAG  1299

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cii-0657Ciona intestinalis65.060.0 576
LLPS-Urm-0025Ursus maritimus50.243e-52 180
LLPS-Tru-1885Triticum urartu49.092e-51 187
LLPS-Amt-1276Amborella trichopoda48.616e-54 186
LLPS-Dio-1606Dipodomys ordii48.01e-72 241
LLPS-Tar-1673Takifugu rubripes45.166e-117 357
LLPS-Hea-1394Helianthus annuus45.02e-51 179
LLPS-Sah-3738Sarcophilus harrisii44.833e-111 345
LLPS-Scm-1612Scophthalmus maximus44.831e-111 344
LLPS-Fud-3354Fukomys damarensis44.623e-108 335
LLPS-Anc-3504Anolis carolinensis44.578e-109 336
LLPS-Cap-3663Cavia porcellus44.394e-108 334
LLPS-Mod-3137Monodelphis domestica44.373e-112 345
LLPS-Pof-2653Poecilia formosa44.273e-111 342
LLPS-Ten-3779Tetraodon nigroviridis44.248e-115 352
LLPS-Gaa-2457Gasterosteus aculeatus44.143e-114 350
LLPS-Xim-0337Xiphophorus maculatus44.013e-112 345
LLPS-Lac-3717Latimeria chalumnae44.011e-111 343
LLPS-Sus-4387Sus scrofa43.942e-107 333
LLPS-Myl-1964Myotis lucifugus43.916e-109 337
LLPS-Dar-2429Danio rerio43.812e-108 335
LLPS-Mea-0293Mesocricetus auratus43.712e-106 330
LLPS-Aim-1399Ailuropoda melanoleuca43.682e-108 335
LLPS-Loa-3053Loxodonta africana43.683e-106 330
LLPS-Otg-1788Otolemur garnettii43.683e-108 335
LLPS-Orl-2455Oryzias latipes43.557e-113 347
LLPS-Bot-1624Bos taurus43.456e-108 334
LLPS-Fec-1913Felis catus43.321e-107 333
LLPS-Pes-3550Pelodiscus sinensis43.321e-109 337
LLPS-Gog-4226Gorilla gorilla43.258e-108 333
LLPS-Poa-2645Pongo abelii43.251e-107 333
LLPS-Hos-3001Homo sapiens43.252e-107 333
LLPS-Pat-0069Pan troglodytes43.251e-107 333
LLPS-Pap-3095Pan paniscus43.251e-107 333
LLPS-Tut-0352Tursiops truncatus43.224e-104 324
LLPS-Ova-2416Ovis aries43.223e-107 332
LLPS-Mum-3182Mus musculus43.223e-106 330
LLPS-Caj-0686Callithrix jacchus43.225e-108 334
LLPS-Ict-3545Ictidomys tridecemlineatus43.221e-106 331
LLPS-Orc-3904Oryctolagus cuniculus43.226e-104 324
LLPS-Rhb-2046Rhinopithecus bieti43.223e-108 335
LLPS-Tag-0395Taeniopygia guttata43.096e-109 335
LLPS-Paa-3887Papio anubis42.991e-107 333
LLPS-Aon-2159Aotus nancymaae42.994e-107 332
LLPS-Cea-0323Cercocebus atys42.991e-107 333
LLPS-Maf-3677Macaca fascicularis42.999e-108 333
LLPS-Mam-4429Macaca mulatta42.991e-107 333
LLPS-Caf-0818Canis familiaris42.995e-106 329
LLPS-Eqc-1955Equus caballus42.999e-105 326
LLPS-Cas-4064Carlito syrichta42.991e-104 325
LLPS-Man-3089Macaca nemestrina42.999e-108 333
LLPS-Mal-4690Mandrillus leucophaeus42.962e-107 333
LLPS-Mup-4193Mustela putorius furo42.764e-106 329
LLPS-Ran-1263Rattus norvegicus42.764e-106 329
LLPS-Chs-2121Chlorocebus sabaeus42.765e-107 332
LLPS-Gaga-3104Gallus gallus42.637e-110 339
LLPS-Asm-4098Astyanax mexicanus42.42e-110 340
LLPS-Fia-2257Ficedula albicollis42.46e-108 333
LLPS-Scf-3002Scleropages formosus42.312e-95 302
LLPS-Drm-2300Drosophila melanogaster41.352e-79 263
LLPS-Osl-1404Ostreococcus lucimarinus41.195e-94 297
LLPS-Php-1381Physcomitrella patens40.978e-101 319
LLPS-Meg-1707Meleagris gallopavo40.312e-95 300
LLPS-Mae-1121Manihot esculenta40.181e-92 295
LLPS-Sob-1585Sorghum bicolor40.04e-87 282
LLPS-Viv-0258Vitis vinifera39.656e-89 285
LLPS-Brn-0692Brassica napus39.493e-91 291
LLPS-Leo-2627Lepisosteus oculatus39.45e-94 297
LLPS-Sot-1851Solanum tuberosum39.364e-92 293
LLPS-Met-1716Medicago truncatula39.312e-91 293
LLPS-Arl-2123Arabidopsis lyrata39.265e-85 276
LLPS-Bro-0298Brassica oleracea39.261e-91 292
LLPS-Brr-2150Brassica rapa39.262e-88 283
LLPS-Sei-1881Setaria italica39.251e-84 275
LLPS-Ors-1061Oryza sativa39.223e-85 277
LLPS-Prp-2576Prunus persica39.177e-87 282
LLPS-Brd-1667Brachypodium distachyon39.083e-87 281
LLPS-Icp-2773Ictalurus punctatus39.051e-95 303
LLPS-Art-2684Arabidopsis thaliana38.943e-85 277
LLPS-Hov-1867Hordeum vulgare38.853e-85 277
LLPS-Tra-2315Triticum aestivum38.852e-86 278
LLPS-Dac-2342Daucus carota38.854e-87 282
LLPS-Mua-0016Musa acuminata38.741e-85 277
LLPS-Glm-1859Glycine max38.394e-89 287
LLPS-Orb-1674Oryza barthii38.361e-86 279
LLPS-Pot-1178Populus trichocarpa38.342e-86 281
LLPS-Abg-1361Absidia glauca38.232e-89 285
LLPS-Ori-2191Oryza indica38.133e-86 278
LLPS-Cae-1942Caenorhabditis elegans38.112e-77 255
LLPS-Cus-1380Cucumis sativus37.931e-82 271
LLPS-Phv-0289Phaseolus vulgaris37.934e-90 290
LLPS-Orbr-1219Oryza brachyantha37.937e-84 272
LLPS-Gor-2646Gossypium raimondii37.94e-82 269
LLPS-Org-1967Oryza glaberrima37.812e-83 271
LLPS-Zem-2483Zea mays37.581e-81 270
LLPS-Xet-3600Xenopus tropicalis37.533e-72 241
LLPS-Coc-2008Corchorus capsularis37.334e-73 252
LLPS-Chr-0760Chlamydomonas reinhardtii37.312e-70 237
LLPS-Crn-0917Cryptococcus neoformans37.12e-84 274
LLPS-Nia-2220Nicotiana attenuata37.018e-84 275
LLPS-Nol-2038Nomascus leucogenys36.983e-83 270
LLPS-Sol-2024Solanum lycopersicum36.931e-81 268
LLPS-Thc-0107Theobroma cacao36.827e-78 258
LLPS-Orp-2072Oryza punctata36.783e-77 254
LLPS-Gas-0583Galdieria sulphuraria36.732e-75 248
LLPS-Sem-1051Selaginella moellendorffii36.737e-91 290
LLPS-Via-1145Vigna angularis36.412e-82 268
LLPS-Nec-0472Neurospora crassa36.133e-63 219
LLPS-Tum-1084Tuber melanosporum35.875e-78 257
LLPS-Lep-2111Leersia perrieri35.865e-67 228
LLPS-Spr-1572Sporisorium reilianum35.856e-73 245
LLPS-Miv-1267Microbotryum violaceum35.83e-71 240
LLPS-Fuv-1590Fusarium verticillioides35.787e-65 223
LLPS-Orni-0167Oryza nivara35.73e-67 236
LLPS-Orr-1509Oryza rufipogon35.75e-67 235
LLPS-Dos-1278Dothistroma septosporum35.671e-71 240
LLPS-Trr-0647Trichoderma reesei35.624e-65 224
LLPS-Zyt-1238Zymoseptoria tritici35.573e-71 239
LLPS-Yal-1539Yarrowia lipolytica35.569e-72 240
LLPS-Cogr-1237Colletotrichum graminicola35.483e-62 216
LLPS-Lem-1060Leptosphaeria maculans35.437e-70 236
LLPS-Orgl-0941Oryza glumaepatula35.322e-64 221
LLPS-Coo-1444Colletotrichum orbiculare35.275e-63 218
LLPS-Kop-1216Komagataella pastoris35.243e-70 236
LLPS-Mao-1028Magnaporthe oryzae35.171e-63 220
LLPS-Trv-1329Trichoderma virens35.132e-64 222
LLPS-Orm-1199Oryza meridionalis34.992e-63 218
LLPS-Fuo-1202Fusarium oxysporum34.918e-67 228
LLPS-Beb-1591Beauveria bassiana34.761e-65 225
LLPS-Pyt-1464Pyrenophora teres34.734e-72 242
LLPS-Cog-0428Colletotrichum gloeosporioides34.72e-63 219
LLPS-Scc-1538Schizosaccharomyces cryophilus34.484e-64 220
LLPS-Blg-0942Blumeria graminis34.397e-62 214
LLPS-Pytr-0277Pyrenophora triticirepentis34.353e-69 234
LLPS-Usm-0980Ustilago maydis34.345e-71 240
LLPS-Scj-0310Schizosaccharomyces japonicus34.36e-63 217
LLPS-Scs-0928Sclerotinia sclerotiorum34.271e-64 222
LLPS-Mel-0416Melampsora laricipopulina34.193e-61 213
LLPS-Gag-1476Gaeumannomyces graminis34.097e-59 207
LLPS-Sac-0213Saccharomyces cerevisiae34.03e-60 210
LLPS-Asg-0493Ashbya gossypii33.969e-64 219
LLPS-Ved-0883Verticillium dahliae33.118e-37 144
LLPS-Asfu-0612Aspergillus fumigatus33.052e-50 184
LLPS-Put-0487Puccinia triticina32.782e-55 197
LLPS-Phn-1435Phaeosphaeria nodorum32.737e-61 211
LLPS-Asc-1180Aspergillus clavatus32.334e-49 180
LLPS-Ast-0097Aspergillus terreus32.261e-51 187
LLPS-Nef-1399Neosartorya fischeri32.045e-51 186
LLPS-Fus-0647Fusarium solani31.82e-53 192
LLPS-Scp-0763Schizosaccharomyces pombe31.661e-58 206
LLPS-Cym-0746Cyanidioschyzon merolae31.441e-69 237
LLPS-Aso-1113Aspergillus oryzae30.63e-50 183
LLPS-Asf-0865Aspergillus flavus30.63e-50 183
LLPS-Asni-0334Aspergillus niger29.661e-49 182
LLPS-Pug-1032Puccinia graminis29.611e-48 179
LLPS-Asn-1352Aspergillus nidulans28.667e-31 126