• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cis-0049

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: E3 ubiquitin-protein ligase
Ensembl Gene: ENSCSAVG00000004498.1
Ensembl Protein: ENSCSAVP00000007524.1
Organism: Ciona savignyi
Taxa ID: 51511
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSSSSARRS  GTMKLRLTVF  CAKNICKRDF  FRLPDPFAKI  MVDGSGQCHA  TGTCKATIDP  60
61    KWNQHYDLYV  GKADSITISV  WDNRKVRKKN  GAGFLGCIRI  MSNAINRLKD  TGYQRLDLCK  120
121   QAQYDQEPVR  GQIVVSIESR  DSDDRSPSNP  VIDARSLIPP  QENDLPEGWE  ARMTNGRLQY  180
181   VDHYTRTTQW  ERPTQPCTRG  TRRPHSALLI  SEPDQHRPRI  SSSSGSSEPR  SSLSPPAATD  240
241   PNTNRFRRHK  NFMTRNQLHG  PSAPLPEGYE  QRTTQQGQVY  FLHTQTGVSS  WHDPRIPRNL  300
301   THINPEDLGP  LPSGWELRST  ATGRLYYVDH  SSRTTQFTDP  RIGRYIGQMQ  NRGRKGKNYL  360
361   IEECEQDPQL  PRYKRDLVQK  HKVLRTELQS  QQPQTGHCRL  EIKRSEAFEQ  SYSLIMKMKP  420
421   KDLRKRLMVK  FVGEDGLDYG  GLAREWLYIL  SHEMLNPYYG  LFQYSREDNY  TLQINPDSHI  480
481   NPDHLSYFHF  VGRILGMAVY  HGHYIDGGFT  MLFYKQLLGK  PISLDDMEEV  DPALYKSMKW  540
541   ILQNDIHDVL  DHTFCADHDS  FGERITHELK  PNGANVEVTE  ENKREYVKLY  VNWRFMRGIE  600
601   AQFLSLSKGF  YELIPQHLLR  PFDERELELI  IGGLGKIDLV  DWRKHTKLKH  CSQDSNIVKW  660
661   FWQAVESFDQ  EKRARVLQFV  TGSRVPLQGF  KALQGSTGTQ  GPRLFTIQFI  DSKTDSLPKA  720
721   HTCFNRIDLP  PYETYEKLLD  KLTCAVENTC  GFYTE  755
Nucleotide CDS Sequence (FASTA)
1     GTGTTCTGCG  CCAAGAACAT  CTGCAAGAGG  GACTTTTTCC  GCCTTCCGGA  TCCTTTCGCT  60
61    AAGATTATGG  TCGACGGTTC  AGGCCAGTGT  CACGCCACAG  GAACCTGTAA  AGCGACTATT  120
121   GACCCGAAAT  GGAATCAGCA  TTACGATCTG  TACGTTGGGA  AAGCGGACAG  CATCACCATC  180
181   TCGGTGTGGG  ACAACAGGAA  GGTGCGAAAG  AAGAACGGAG  CCGGTTTCCT  CGGCTGTATA  240
241   CGCATCATGT  CGAACGCCAT  AAACCGACTG  AAAGACACAG  GATATCAGCG  TCTGGACCTG  300
301   TGCAAGCAGG  CCCAATACGA  CCAGGAACCC  GTCAGAGGTC  AAATAGTGGT  GAGCATCGAA  360
361   AGTCGCGACT  CGGACGACCG  GTCACCCTCC  AACCCGGTCA  TAGACGCGAG  GTCCCTCATC  420
421   CCACCGCAGG  AAAACGACCT  CCCCGAAGGC  TGGGAGGCCA  GGATGACCAA  CGGACGCCTT  480
481   CAGTACGTTG  ATCATTACAC  GAGAACCACG  CAGTGGGAAC  GACCAACGCA  GCCTTGCACA  540
541   CGAGGCACCC  GCCGCCCACA  CAGCGCCCTC  CTCATCTCCG  AGCCCGACCA  GCACCGACCG  600
601   CGCATCTCGA  GCAGCAGCGG  AAGTTCCGAG  CCCCGGTCCT  CCCTCAGTCC  ACCCGCCGCC  660
661   ACCGACCCGA  ACACAAATCG  ATTCCGGCGC  CACAAGAACT  TCATGACCCG  CAACCAGTTA  720
721   CACGGACCCT  CCGCGCCCCT  GCCCGAGGGC  TACGAGCAAC  GGACTACCCA  GCAGGGTCAG  780
781   GTGTATTTCC  TGCACACCCA  AACGGGGGTA  TCGTCGTGGC  ACGACCCGCG  CATACCACGG  840
841   AACTTAACTC  ACATAAACCC  GGAGGACTTG  GGCCCTTTGC  CTTCGGGCTG  GGAATTACGC  900
901   TCGACGGCCA  CGGGTCGACT  TTATTACGTG  GACCACTCTA  GCAGGACCAC  CCAGTTCACC  960
961   GACCCGAGGA  TTGGTCGATA  TATCGGTCAA  ATGCAGAACA  GAGGGAGAAA  AGGAAAACGG  1020
1021  ATGACATTAA  AAAGTCACGT  GATCACAGTC  GGGTTATTTG  AGACATTGTC  GTGTGTGGTT  1080
1081  GTTCTACCTC  GCTACAAACG  CGATCTGGTG  CAGAAGCACA  AGGTTCTACG  CACCGAGCTG  1140
1141  CAGTCGCAGC  AGCCACAGAC  CGGCCATTGT  CGTCTGGAAA  TCAAGCGATC  CGAAGCTTTC  1200
1201  GAGCAGTCGT  ACAGCCTTAT  TATGAAGATG  AAACCAAAAG  ATTTACGGAA  ACGTCTAATG  1260
1261  GTGAAATTCG  TGGGCGAGGA  TGGATTGGAT  TATGGCGGCC  TTGCTAGAGA  ATGGCTCTAT  1320
1321  ATTTTATCGC  ATGAGATGCT  AAACCCTTAC  TACGGATTAT  TCCAGTACTC  CCGCGAGGAC  1380
1381  AACTACACTC  TTCAAATCAA  CCCCGATTCG  CACATCAACC  CCGACCACCT  TTCCTACTTC  1440
1441  CACTTCGTCG  GCCGCATACT  GGGCATGGCG  GTCTACCACG  GCCACTACAT  CGACGGCGGC  1500
1501  TTCACCATGT  TGTTCTACAA  GCAACTCCTC  GGGAAACCGA  TCTCGCTCGA  CGATATGGAA  1560
1561  GAGGTCGACC  CCGCGTTGTA  CAAGTCGATG  AAGTGGATCC  TGCAGAACGA  CATCCACGAC  1620
1621  GTGCTCGACC  ACACATTCTG  CGCCGACCAC  GACTCCTTCG  GCGAGCGGAT  CACGCACGAG  1680
1681  CTCAAGCCGA  ACGGCGCGAA  CGTGGAGGTA  ACGGAAGAGA  ACAAGCGCGA  ATACGTCAAG  1740
1741  CTCTACGTCA  ACTGGAGATT  CATGCGAGGG  ATCGAAGCCC  AGTTCCTTTC  CCTTTCGAAG  1800
1801  GGCTTCTACG  AGTTGATCCC  GCAACATCTT  CTACGTCCGT  TCGACGAGCG  CGAGTTGGAG  1860
1861  CTGATCATCG  GAGGACTTGG  GAAGATCGAC  CTCGTGGACT  GGAGGAAGCA  CACAAAGCTG  1920
1921  AAGCATTGCT  CTCAGGACTC  CAACATCGTC  AAGTGGTTCT  GGCAAGCCGT  CGAGAGCTTC  1980
1981  GACCAGGAGA  AGAGAGCAAG  GGTATTGCAG  TTTGTCACTG  GTTCTAGGGT  ACCATTGCAA  2040
2041  GGCTTCAAAG  CGTTACAGGG  CTCCACTGGA  ACCCAAGGTC  CCCGCCTTTT  CACCATTCAA  2100
2101  TTCATTGATA  GCAAAACTGA  TAGCTTACCT  AAAGCCCACA  CCTGTTTCAA  CCGGATTGAT  2160
2161  CTGCCGCCTT  ACGAAACCTA  CGAAAAGCTG  CTCGATAAAC  TCACGTGCGC  GGTGGAGAAT  2220
2221  ACGTGCGGCT  TCTACACCGA  GTAA  2244

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cii-0636Ciona intestinalis89.160.01357
LLPS-Drm-0518Drosophila melanogaster70.10.0 588
LLPS-Mal-0204Mandrillus leucophaeus69.940.0 765
LLPS-Anp-0257Anas platyrhynchos65.190.01004
LLPS-Mod-2345Monodelphis domestica65.130.01008
LLPS-Maf-1812Macaca fascicularis65.040.01008
LLPS-Mam-0996Macaca mulatta65.040.01008
LLPS-Mup-1090Mustela putorius furo65.030.0 997
LLPS-Mum-3617Mus musculus64.910.01007
LLPS-Sus-1641Sus scrofa64.910.01007
LLPS-Caj-0952Callithrix jacchus64.910.01004
LLPS-Poa-1109Pongo abelii64.910.01005
LLPS-Fec-1126Felis catus64.910.01007
LLPS-Hos-1170Homo sapiens64.910.01005
LLPS-Orc-0815Oryctolagus cuniculus64.910.01007
LLPS-Man-1651Macaca nemestrina64.890.0 999
LLPS-Myl-2136Myotis lucifugus64.850.0 998
LLPS-Urm-0930Ursus maritimus64.850.01000
LLPS-Loa-1269Loxodonta africana64.850.0 998
LLPS-Tag-1729Taeniopygia guttata64.840.01007
LLPS-Cap-0512Cavia porcellus64.80.0 996
LLPS-Pap-0424Pan paniscus64.80.0 994
LLPS-Aim-3066Ailuropoda melanoleuca64.720.01001
LLPS-Eqc-0319Equus caballus64.720.01001
LLPS-Fud-0103Fukomys damarensis64.670.0 996
LLPS-Pes-2136Pelodiscus sinensis64.670.0 996
LLPS-Bot-0173Bos taurus64.630.0 997
LLPS-Ova-1992Ovis aries64.580.0 995
LLPS-Ict-0428Ictidomys tridecemlineatus64.540.0 994
LLPS-Lac-2723Latimeria chalumnae64.540.01006
LLPS-Anc-0840Anolis carolinensis64.530.01007
LLPS-Nol-0601Nomascus leucogenys64.490.0 993
LLPS-Gog-3243Gorilla gorilla64.420.0 972
LLPS-Scf-0042Scleropages formosus64.180.0 999
LLPS-Fia-0238Ficedula albicollis64.090.0 999
LLPS-Gaa-0143Gasterosteus aculeatus64.070.0 998
LLPS-Orn-1221Oreochromis niloticus63.980.01001
LLPS-Ere-0264Erinaceus europaeus63.90.0 920
LLPS-Sah-1092Sarcophilus harrisii63.860.0 901
LLPS-Orl-0591Oryzias latipes63.610.01002
LLPS-Otg-4058Otolemur garnettii63.520.0 975
LLPS-Pof-2001Poecilia formosa63.480.01003
LLPS-Icp-2379Ictalurus punctatus63.450.0 998
LLPS-Scm-0694Scophthalmus maximus63.310.01005
LLPS-Pat-4472Pan troglodytes63.270.0 943
LLPS-Ran-2295Rattus norvegicus63.210.0 830
LLPS-Ora-0540Ornithorhynchus anatinus63.170.01001
LLPS-Dar-3190Danio rerio63.060.01005
LLPS-Tar-2563Takifugu rubripes63.050.0 998
LLPS-Dio-0763Dipodomys ordii63.020.0 967
LLPS-Gaga-2939Gallus gallus62.650.0 954
LLPS-Asm-0827Astyanax mexicanus62.10.0 983
LLPS-Xim-1160Xiphophorus maculatus61.960.0 996
LLPS-Aon-3165Aotus nancymaae61.740.0 938
LLPS-Paa-0783Papio anubis61.650.0 922
LLPS-Ten-0065Tetraodon nigroviridis61.650.0 817
LLPS-Leo-1582Lepisosteus oculatus61.130.0 967
LLPS-Cea-2658Cercocebus atys60.510.0 781
LLPS-Tut-1124Tursiops truncatus60.00.0 840
LLPS-Rhb-3802Rhinopithecus bieti58.220.0 872
LLPS-Xet-2909Xenopus tropicalis54.20.0 764
LLPS-Aso-0034Aspergillus oryzae50.176e-100 317
LLPS-Mel-1264Melampsora laricipopulina47.825e-162 497
LLPS-Pug-0738Puccinia graminis47.022e-162 494
LLPS-Yal-0673Yarrowia lipolytica46.634e-159 490
LLPS-Put-1287Puccinia triticina46.629e-136 426
LLPS-Zyt-0373Zymoseptoria tritici46.149e-154 475
LLPS-Map-0232Magnaporthe poae45.652e-148 466
LLPS-Abg-0289Absidia glauca45.074e-90 317
LLPS-Kop-1362Komagataella pastoris44.993e-88 312
LLPS-Scj-1448Schizosaccharomyces japonicus44.667e-91 320
LLPS-Asg-0016Ashbya gossypii44.543e-167 510
LLPS-Crn-1399Cryptococcus neoformans44.444e-89 315
LLPS-Sac-0388Saccharomyces cerevisiae44.34e-165 504
LLPS-Spr-0895Sporisorium reilianum44.233e-166 509
LLPS-Scs-0053Sclerotinia sclerotiorum44.228e-162 496
LLPS-Miv-0848Microbotryum violaceum44.022e-165 506
LLPS-Ast-1325Aspergillus terreus43.932e-161 495
LLPS-Trr-1005Trichoderma reesei43.817e-161 493
LLPS-Caf-2959Canis familiaris43.86e-150 469
LLPS-Asc-0963Aspergillus clavatus43.778e-162 497
LLPS-Fuv-1348Fusarium verticillioides43.771e-161 495
LLPS-Fuo-0286Fusarium oxysporum43.771e-161 495
LLPS-Asfu-0575Aspergillus fumigatus43.683e-0758.5
LLPS-Cas-2849Carlito syrichta43.645e-150 469
LLPS-Asf-0947Aspergillus flavus43.614e-160 491
LLPS-Nef-0660Neosartorya fischeri43.618e-161 493
LLPS-Trv-1090Trichoderma virens43.64e-160 491
LLPS-Mao-0563Magnaporthe oryzae43.191e-160 493
LLPS-Meg-0718Meleagris gallopavo43.191e-156 485
LLPS-Fus-0792Fusarium solani43.163e-160 492
LLPS-Chs-0154Chlorocebus sabaeus43.112e-149 466
LLPS-Nec-1247Neurospora crassa43.15e-165 504
LLPS-Gag-0565Gaeumannomyces graminis43.091e-158 488
LLPS-Cogr-1032Colletotrichum graminicola43.099e-162 496
LLPS-Phn-0719Phaeosphaeria nodorum43.02e-159 491
LLPS-Pyt-0220Pyrenophora teres42.885e-160 491
LLPS-Pytr-0235Pyrenophora triticirepentis42.885e-160 491
LLPS-Cog-1074Colletotrichum gloeosporioides42.831e-159 490
LLPS-Asn-1238Aspergillus nidulans42.812e-160 493
LLPS-Coo-0973Colletotrichum orbiculare42.742e-160 493
LLPS-Scc-0776Schizosaccharomyces cryophilus42.73e-85 303
LLPS-Asni-1564Aspergillus niger42.585e-86 305
LLPS-Ved-0496Verticillium dahliae42.54e-161 494
LLPS-Beb-0263Beauveria bassiana42.485e-157 484
LLPS-Mea-4136Mesocricetus auratus42.386e-157 484
LLPS-Gas-0834Galdieria sulphuraria42.114e-89 311
LLPS-Blg-1136Blumeria graminis42.081e-159 490
LLPS-Scp-1455Schizosaccharomyces pombe41.967e-86 305
LLPS-Tum-0196Tuber melanosporum41.94e-89 315
LLPS-Cae-0459Caenorhabditis elegans41.491e-146 456
LLPS-Dos-0166Dothistroma septosporum41.242e-162 498
LLPS-Usm-0057Ustilago maydis36.082e-169 517