• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Chs-2569
SMAD1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Mothers against decapentaplegic homolog
Gene Name: SMAD1
Ensembl Gene: ENSCSAG00000003430.1
Ensembl Protein: ENSCSAP00000014620.1
Organism: Chlorocebus sabaeus
Taxa ID: 60711
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNVTSLFSFT  SPAVKRLLGW  KQGDEEEKWA  EKAVDALVKK  LKKKKGAMEE  LEKALSCPGQ  60
61    PSNCVTIPRS  LDGRLHVSHR  KGLPHVIYCR  VWRWPDLQSH  HELKPLECCE  FPFGSKQKEV  120
121   CINPYHYKRV  ESPVLPPVLV  PRHSEYNPQH  SLLAQFRNLG  QNEPHMPLNA  TFPDSFQQPN  180
181   SHPFPHSPNS  SYPNSPGSSS  STYPHSPTSS  DPGSPFQMPA  DTPPPAYLPP  EDPMTQDGSQ  240
241   PMDTNMMAPP  LPSEINRGDV  QAVAYEEPKH  WCSIVYYELN  NRVGEAFHAS  STSVLVDGFT  300
301   DPSNNKNRFC  LGLLSNVNRN  STIENTRRHI  GKGVHLYYVG  GEVYAECLSD  SSIFVQSRNC  360
361   NYHHGFHPTT  VCKIPSGCSL  KIFNNQEFAQ  LLAQSVNHGF  ETVYELTKMC  TIRMSFVKGW  420
421   GAEYHRQDVT  STPCWIEIHL  HGPLQWLDKV  LTQMGSPHNP  ISSVS  465
Nucleotide CDS Sequence (FASTA)
1     ATGAATGTGA  CAAGTTTATT  TTCCTTTACA  AGTCCAGCTG  TGAAAAGACT  TCTTGGGTGG  60
61    AAACAGGGCG  ATGAAGAAGA  AAAATGGGCA  GAGAAAGCTG  TTGATGCTTT  GGTGAAAAAA  120
121   CTGAAGAAAA  AGAAAGGTGC  CATGGAGGAA  CTGGAGAAGG  CCTTGAGCTG  CCCAGGGCAA  180
181   CCAAGTAACT  GTGTCACCAT  TCCCCGCTCT  TTGGATGGCA  GGCTGCACGT  CTCCCACCGG  240
241   AAGGGACTGC  CTCATGTCAT  TTACTGCCGT  GTATGGCGCT  GGCCTGATCT  TCAGAGCCAC  300
301   CATGAACTAA  AACCACTGGA  ATGCTGTGAG  TTTCCTTTTG  GTTCTAAGCA  GAAGGAAGTC  360
361   TGCATCAATC  CCTACCACTA  TAAGCGAGTA  GAAAGCCCTG  TACTTCCTCC  TGTGCTGGTT  420
421   CCAAGACACA  GCGAATATAA  TCCTCAGCAC  AGCCTCTTAG  CTCAGTTCCG  TAACTTAGGA  480
481   CAAAATGAGC  CTCACATGCC  ACTCAACGCC  ACTTTTCCAG  ATTCTTTCCA  GCAACCCAAC  540
541   AGCCACCCGT  TTCCTCACTC  TCCCAATAGC  AGTTACCCAA  ACTCTCCTGG  GAGCAGCAGC  600
601   AGCACCTACC  CTCACTCTCC  CACCAGCTCA  GACCCAGGAA  GTCCTTTCCA  GATGCCAGCT  660
661   GATACGCCCC  CACCTGCTTA  CCTGCCTCCT  GAAGACCCCA  TGACCCAGGA  TGGCTCCCAG  720
721   CCGATGGACA  CAAACATGAT  GGCGCCTCCC  CTGCCCTCAG  AAATCAACAG  AGGAGATGTT  780
781   CAGGCGGTTG  CTTATGAGGA  ACCAAAACAC  TGGTGCTCTA  TTGTCTACTA  TGAGCTCAAC  840
841   AATCGTGTGG  GTGAAGCTTT  CCATGCCTCC  TCCACAAGTG  TGTTGGTGGA  TGGTTTCACT  900
901   GATCCTTCCA  ACAATAAGAA  CCGTTTCTGC  CTTGGGCTGC  TCTCCAATGT  TAACCGGAAT  960
961   TCCACTATTG  AAAACACCAG  GCGGCATATT  GGAAAAGGGG  TTCATCTTTA  TTATGTTGGA  1020
1021  GGGGAGGTAT  ATGCCGAATG  CCTTAGTGAC  AGTAGCATCT  TTGTGCAAAG  TCGGAACTGC  1080
1081  AACTACCATC  ATGGATTTCA  TCCTACTACT  GTTTGCAAGA  TCCCTAGTGG  GTGTAGTCTG  1140
1141  AAAATTTTTA  ACAACCAAGA  ATTTGCTCAG  TTATTGGCAC  AGTCTGTGAA  TCATGGATTT  1200
1201  GAGACAGTCT  ATGAGCTTAC  AAAAATGTGT  ACTATACGTA  TGAGCTTTGT  GAAGGGCTGG  1260
1261  GGAGCAGAAT  ACCACCGCCA  GGATGTTACT  AGCACCCCCT  GCTGGATTGA  GATACATCTG  1320
1321  CACGGCCCCC  TCCAGTGGCT  GGATAAAGTT  CTTACTCAAA  TGGGTTCACC  TCATAATCCT  1380
1381  ATTTCATCTG  TGTCTTAA  1398

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mal-1299Mandrillus leucophaeus99.780.0 776
LLPS-Cea-1865Cercocebus atys99.780.0 776
LLPS-Maf-3778Macaca fascicularis99.780.0 776
LLPS-Mam-1185Macaca mulatta99.780.0 776
LLPS-Man-3246Macaca nemestrina99.780.0 776
LLPS-Hos-2404Homo sapiens99.780.0 776
LLPS-Rhb-3875Rhinopithecus bieti99.780.0 776
LLPS-Bot-2291Bos taurus99.570.0 773
LLPS-Ova-2387Ovis aries99.570.0 773
LLPS-Aon-2676Aotus nancymaae99.570.0 775
LLPS-Sus-2704Sus scrofa99.570.0 773
LLPS-Gog-2419Gorilla gorilla99.570.0 774
LLPS-Ict-2089Ictidomys tridecemlineatus99.570.0 773
LLPS-Nol-3368Nomascus leucogenys99.570.0 774
LLPS-Cas-0788Carlito syrichta99.570.0 775
LLPS-Pap-3951Pan paniscus99.570.0 775
LLPS-Myl-1303Myotis lucifugus99.350.0 771
LLPS-Fud-1752Fukomys damarensis99.350.0 771
LLPS-Eqc-3139Equus caballus99.350.0 772
LLPS-Loa-1748Loxodonta africana99.350.0 771
LLPS-Mup-3418Mustela putorius furo99.140.0 771
LLPS-Aim-3716Ailuropoda melanoleuca99.140.0 771
LLPS-Caj-2309Callithrix jacchus99.140.0 769
LLPS-Caf-1956Canis familiaris99.140.0 771
LLPS-Mod-0340Monodelphis domestica99.140.0 772
LLPS-Fec-2013Felis catus99.140.0 771
LLPS-Urm-2076Ursus maritimus99.140.0 771
LLPS-Pat-0619Pan troglodytes99.140.0 766
LLPS-Sah-4081Sarcophilus harrisii98.920.0 771
LLPS-Mea-1591Mesocricetus auratus98.920.0 771
LLPS-Mum-2965Mus musculus98.920.0 771
LLPS-Otg-0686Otolemur garnettii98.920.0 773
LLPS-Paa-3234Papio anubis98.910.0 753
LLPS-Tut-1345Tursiops truncatus98.710.0 769
LLPS-Ora-2605Ornithorhynchus anatinus98.710.0 769
LLPS-Cap-0855Cavia porcellus98.710.0 764
LLPS-Dio-0307Dipodomys ordii98.490.0 763
LLPS-Ran-0747Rattus norvegicus97.860.0 763
LLPS-Anc-1633Anolis carolinensis97.420.0 763
LLPS-Orc-2227Oryctolagus cuniculus97.420.0 749
LLPS-Ere-0430Erinaceus europaeus96.990.0 767
LLPS-Gaga-2124Gallus gallus96.990.0 753
LLPS-Fia-0887Ficedula albicollis96.770.0 755
LLPS-Tag-1750Taeniopygia guttata96.560.0 756
LLPS-Meg-2438Meleagris gallopavo96.560.0 751
LLPS-Lac-1958Latimeria chalumnae95.280.0 749
LLPS-Anp-1169Anas platyrhynchos94.430.0 749
LLPS-Xet-3615Xenopus tropicalis94.190.0 743
LLPS-Xim-0666Xiphophorus maculatus93.569e-154 454
LLPS-Pes-3085Pelodiscus sinensis92.960.0 646
LLPS-Leo-3504Lepisosteus oculatus91.670.0 711
LLPS-Orn-0170Oreochromis niloticus88.030.0 693
LLPS-Poa-2174Pongo abelii87.960.0 692
LLPS-Ten-2056Tetraodon nigroviridis86.810.0 690
LLPS-Asm-2150Astyanax mexicanus86.210.0 686
LLPS-Scf-4197Scleropages formosus86.080.0 675
LLPS-Icp-3811Ictalurus punctatus85.990.0 683
LLPS-Tar-2849Takifugu rubripes85.960.0 690
LLPS-Scm-2305Scophthalmus maximus85.870.0 679
LLPS-Dar-3538Danio rerio85.780.0 684
LLPS-Gaa-2987Gasterosteus aculeatus85.770.0 688
LLPS-Orl-2056Oryzias latipes85.350.0 682
LLPS-Pof-0435Poecilia formosa80.490.0 672