• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cea-3204
AKT1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: AKT1
Ensembl Gene: ENSCATG00000019504.1
Ensembl Protein: ENSCATP00000006788.1
Organism: Cercocebus atys
Taxa ID: 9531
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSDVAIVKEG  WLHKRGEYIK  TWRPRYFLLK  NDGTFIGYKE  RPQDVDQREA  PLNNFSVAQC  60
61    QLMKTERPRP  NTFIIRCLQW  TTVIERTFHV  ETPEEREEWT  TAIQTVADGL  KKHEEEMMDF  120
121   RSGSPSDNSG  AEEMEVSLAK  PKHRVTMNEF  EYLKLLGKGT  FGKVILVKEK  ATGRYYAMKI  180
181   LKKEVIVAKD  EVAHTLTENR  VLQNSRHPFL  TALKYSFQTH  DRLCFVMEYA  NGGELFFHLS  240
241   RERVFSEDRA  RFYGAEIVSA  LDYLHSEKNV  VYRDLKLENL  MLDKDGHIKI  TDFGLCKEGI  300
301   KDGATMKTFC  GTPEYLAPEV  LEDNDYGRAV  DWWGLGVVMY  EMMCGRLPFY  NQDHEKLFEL  360
361   ILMEEIRFPR  TLGPEAKSLL  SGLLKKDPKQ  RLGGGSEDAK  EIMQHRFFAG  IVWQHVYEKK  420
421   LSPPFKPQVT  SETDTRYFDE  EFTAQMITIT  PPDQDDSMEC  VDSERRPHFP  QFSYSASGTA  480
Nucleotide CDS Sequence (FASTA)
1     ATGGCCCTCA  CCACCTGCAC  GTCCGTAGGG  GAGTACATCA  AGACCTGGCG  ACCACGCTAC  60
61    TTCCTCCTCA  AGAATGATGG  CACTTTCATT  GGCTATAAGG  AGCGGCCGCA  GGACGTGGAC  120
121   CAACGTGAGG  CCCCCCTCAA  CAACTTCTCT  GTGGCACAGT  GCCAGCTGAT  GAAGACGGAG  180
181   CGGCCCCGGC  CCAACACCTT  CATCATCCGC  TGCCTGCAGT  GGACCACTGT  CATCGAACGC  240
241   ACCTTCCACG  TGGAGACTCC  CGAGGAGCGG  GAGGAGTGGA  CAACCGCCAT  CCAGACAGTG  300
301   GCCGATGGCC  TCAAGAAGCA  CGAGGAGGAG  ATGATGGACT  TCCGGTCGGG  CTCACCCAGC  360
361   GACAACTCAG  GGGCTGAAGA  GATGGAGGTG  TCCCTGGCCA  AACCCAAGCA  CCGTGTGACC  420
421   ATGAACGAGT  TTGAGTACCT  GAAGCTGCTG  GGCAAGGGCA  CTTTCGGGAA  GGTGATCCTG  480
481   GTGAAGGAGA  AGGCAACGGG  CCGCTACTAC  GCCATGAAGA  TCCTCAAGAA  GGAGGTCATC  540
541   GTGGCCAAGG  ACGAGGTGGC  CCACACACTC  ACCGAGAACC  GTGTTCTGCA  GAACTCCAGG  600
601   CACCCCTTCC  TCACGGCCCT  GAAGTACTCC  TTCCAGACCC  ACGACCGCCT  CTGCTTCGTC  660
661   ATGGAGTACG  CCAATGGGGG  CGAGCTCTTT  TTCCACCTGT  CCCGGGAGCG  TGTGTTCTCT  720
721   GAGGACCGGG  CCCGCTTCTA  TGGCGCCGAG  ATCGTGTCAG  CCCTGGACTA  CCTGCACTCG  780
781   GAGAAGAATG  TGGTGTACCG  GGACCTCAAG  GTGCTGGAGG  ACAATGACTA  CGGCCGTGCG  840
841   GTGGACTGGT  GGGGGCTGGG  CGTGGTCATG  TATGAGATGA  TGTGCGGCCG  CCTGCCCTTC  900
901   TACAACCAGG  ACCACGAGAA  GCTTTTTGAG  CTCATCCTCA  TGGAAGAGAT  CCGCTTCCCG  960
961   CGCACGCTTG  GTCCTGAGGC  CAAGTCCTTG  CTCTCAGGGC  TGCTCAAGAA  GGACCCCAAG  1020
1021  CAGAGGCTTG  GCGGGGGCTC  TGAGGACGCC  AAGGAGATCA  TGCAGCATCG  CTTCTTTGCC  1080
1081  GGCATCGTGT  GGCAGCACGT  GTATGAGAAG  AAGCTCAGCC  CACCCTTCAA  GCCCCAGGTC  1140
1141  ACATCGGAGA  CCGACACCAG  GTATTTTGAT  GAGGAGTTCA  CGGCCCAGAT  GATCACCATC  1200
1201  ACACCACCTG  ACCAAGACGA  CAGCATGGAG  TGCGTGGACA  GCGAGCGCAG  GCCCCACTTC  1260
1261  CCCCAGTTCT  CCTACTCGGC  CAGCGGCACG  GCCTGA  1296

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-0964Papio anubis100.00.01005
LLPS-Maf-2720Macaca fascicularis100.00.01005
LLPS-Chs-0616Chlorocebus sabaeus100.00.01005
LLPS-Mam-2488Macaca mulatta100.00.01005
LLPS-Man-2254Macaca nemestrina100.00.01005
LLPS-Hos-3213Homo sapiens99.580.01000
LLPS-Pat-2329Pan troglodytes99.580.01000
LLPS-Nol-3560Nomascus leucogenys99.140.0 960
LLPS-Mea-3378Mesocricetus auratus98.330.0 989
LLPS-Ict-0663Ictidomys tridecemlineatus98.330.0 990
LLPS-Mum-2098Mus musculus98.120.0 987
LLPS-Ran-2453Rattus norvegicus97.920.0 986
LLPS-Cap-3568Cavia porcellus97.920.0 988
LLPS-Otg-3541Otolemur garnettii97.710.0 987
LLPS-Gog-3582Gorilla gorilla97.560.0 912
LLPS-Fud-2624Fukomys damarensis97.50.0 984
LLPS-Sus-4145Sus scrofa97.290.0 978
LLPS-Bot-2236Bos taurus97.080.0 976
LLPS-Caf-3746Canis familiaris96.880.0 973
LLPS-Fec-3548Felis catus96.670.0 971
LLPS-Pap-2091Pan paniscus96.630.0 889
LLPS-Eqc-4403Equus caballus96.320.0 922
LLPS-Gaga-0384Gallus gallus96.250.0 973
LLPS-Fia-0575Ficedula albicollis96.250.0 973
LLPS-Urm-0439Ursus maritimus96.130.0 924
LLPS-Tag-3133Taeniopygia guttata95.850.0 969
LLPS-Pes-0601Pelodiscus sinensis95.830.0 971
LLPS-Mup-0113Mustela putorius furo95.620.0 962
LLPS-Sah-3467Sarcophilus harrisii95.620.0 967
LLPS-Mod-2135Monodelphis domestica95.620.0 968
LLPS-Anc-2367Anolis carolinensis95.420.0 970
LLPS-Anp-0760Anas platyrhynchos94.590.0 956
LLPS-Meg-1485Meleagris gallopavo93.960.0 948
LLPS-Rhb-1537Rhinopithecus bieti91.260.0 906
LLPS-Lac-2018Latimeria chalumnae90.990.0 899
LLPS-Xet-3673Xenopus tropicalis90.50.0 910
LLPS-Caj-3789Callithrix jacchus90.210.0 887
LLPS-Leo-1824Lepisosteus oculatus90.210.0 913
LLPS-Scm-3934Scophthalmus maximus90.110.0 873
LLPS-Orl-1633Oryzias latipes89.890.0 869
LLPS-Pof-3065Poecilia formosa89.890.0 866
LLPS-Aon-2552Aotus nancymaae89.790.0 880
LLPS-Ten-3432Tetraodon nigroviridis89.190.0 888
LLPS-Tar-3962Takifugu rubripes89.170.0 892
LLPS-Icp-1830Ictalurus punctatus89.170.0 893
LLPS-Scf-3016Scleropages formosus89.050.0 874
LLPS-Xim-3316Xiphophorus maculatus88.960.0 890
LLPS-Asm-3221Astyanax mexicanus88.960.0 889
LLPS-Orn-3620Oreochromis niloticus88.630.0 868
LLPS-Cii-1379Ciona intestinalis64.330.0 654
LLPS-Cis-0794Ciona savignyi60.620.0 618
LLPS-Cae-1215Caenorhabditis elegans55.210.0 576
LLPS-Tut-0914Tursiops truncatus49.551e-105 328
LLPS-Sem-1872Selaginella moellendorffii48.043e-102 316