• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cea-2429
MCM5

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DNA helicase
Gene Name: MCM5
Ensembl Gene: ENSCATG00000043913.1
Ensembl Protein: ENSCATP00000042643.1
Organism: Cercocebus atys
Taxa ID: 9531
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nucleolus, Centrosome/Spindle pole body, Stress granule, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSGFDDPGIF  YSDSFGGDAP  ADEGQARKSQ  LQRRFKEFLR  QYRVGTDRTG  FTFKYRDELK  60
61    RHYNLGEYWI  EVEMEDLASF  DEDLADYLYK  QPAEHLQLLE  EAAKEVADEV  TRPRPSGEEV  120
121   LQDIQVMLKS  DASPSSIRSL  KSDMMSHLVK  IPGIIIAASA  VRAKATRISI  QCRSCRNTLT  180
181   NIAMRPGLEG  YALPRKCNTD  QAGRPKCPLD  PYFIMPDKCK  CVDFQTLKLQ  ELPDAVPHGE  240
241   MPRHMQLYCD  RYLCDKVVPG  NRVTIMGIYS  IKKFGLTSSR  GRDRVGVGIR  SSYIRVLGIQ  300
301   VDTDGSGRSF  AGAVSPQEEE  EFRRLAALPN  VYEVISKSIA  PSIFGGTDMK  KAIACLLFGG  360
361   SRKRLPDGLT  RRGDINLLML  GDPGTAKSQL  LKFVEKCSPI  GVYTSGKGSS  AAGLTASVMR  420
421   DPSSRNFIME  GGAMVLADGG  VVCIDEFDKM  REDDRVAIHE  AMEQQTISIA  KAGITTTLNS  480
481   RCSVLAAANS  VFGRWDETKG  EDNIDFMPTI  LSRFDMIFIV  KDEHNEERDV  MLAKHVITLH  540
541   VSALTQTQAV  EGEIDLAKLK  KFIAYCRAKC  GPRLSAEAAE  KLKNRYIIMR  SGARQHERDS  600
601   DRRSSIPITV  RQLEAIVRIA  ESLSKMKLQP  FATEADVEEA  LRLFQVSTLD  AALSGTLSGV  660
661   EGFTSQEDQE  MLSRIEKQLK  RRFAIGSQVS  EHSIIKDFTK  QKYPEHAIHK  VLQLMLRRGE  720
721   IQHRMQRKVL  YRLK  734
Nucleotide CDS Sequence (FASTA)
1     ATGTCGGGAT  TCGACGATCC  TGGCATTTTC  TACAGCGACA  GCTTCGGGGG  CGACGCCCCG  60
61    GCCGACGAGG  GGCAGGCCCG  CAAATCGCAG  CTGCAGAGGC  GCTTCAAGGA  GTTCCTGCGG  120
121   CAGTACCGAG  TGGGCACCGA  CCGCACGGGC  TTCACCTTCA  AATACAGGGA  TGAACTCAAG  180
181   CGGCATTACA  ACCTGGGGGA  GTACTGGATT  GAGGTGGAGA  TGGAGGATCT  GGCCAGCTTT  240
241   GATGAGGACC  TGGCCGACTA  CTTGTACAAG  CAGCCAGCCG  AGCACCTGCA  GCTGCTTGAG  300
301   GAAGCTGCCA  AGGAAGTAGC  TGATGAGGTG  ACCCGGCCCC  GGCCTTCAGG  GGAGGAGGTG  360
361   CTCCAGGACA  TCCAGGTCAT  GCTCAAGTCG  GATGCCAGCC  CTTCCAGCAT  TCGTAGCCTG  420
421   AAGTCGGACA  TGATGTCACA  CCTGGTGAAG  ATCCCCGGCA  TCATCATCGC  GGCGTCTGCG  480
481   GTCCGTGCCA  AGGCCACCCG  CATCTCTATC  CAGTGCCGCA  GCTGCCGCAA  CACCCTCACC  540
541   AACATTGCCA  TGCGCCCTGG  CCTGGAGGGC  TATGCCCTGC  CCAGGAAGTG  CAACACAGAT  600
601   CAGGCTGGGC  GCCCCAAGTG  CCCACTGGAC  CCGTACTTCA  TCATGCCCGA  CAAATGCAAA  660
661   TGCGTGGACT  TCCAGACCCT  GAAGCTGCAG  GAGCTGCCTG  ATGCAGTCCC  CCACGGGGAG  720
721   ATGCCCAGAC  ACATGCAGCT  CTACTGTGAC  AGGTACCTGT  GTGACAAGGT  CGTCCCTGGG  780
781   AACAGGGTTA  CCATCATGGG  CATCTACTCC  ATCAAGAAGT  TTGGCCTGAC  CTCCAGCAGG  840
841   GGCCGTGACA  GGGTGGGCGT  GGGCATCCGA  AGCTCCTACA  TCCGTGTCCT  GGGCATCCAG  900
901   GTGGACACGG  ATGGCTCTGG  CCGCAGCTTT  GCTGGGGCCG  TGAGCCCGCA  GGAGGAGGAG  960
961   GAGTTCCGTC  GCCTGGCTGC  CCTCCCCAAT  GTCTATGAGG  TCATCTCCAA  GAGCATCGCC  1020
1021  CCCTCCATCT  TTGGGGGCAC  GGACATGAAG  AAGGCCATTG  CCTGCCTGCT  CTTTGGGGGC  1080
1081  TCCCGAAAGA  GGCTCCCTGA  TGGACTTACT  CGCCGAGGAG  ACATCAACCT  GCTGATGCTA  1140
1141  GGGGACCCTG  GGACAGCCAA  GTCCCAGCTT  CTGAAGTTTG  TGGAGAAGTG  TTCTCCCATT  1200
1201  GGGGTATACA  CGTCTGGGAA  AGGCAGCAGT  GCAGCCGGAC  TGACAGCCTC  AGTGATGAGG  1260
1261  GATCCTTCGT  CTCGGAATTT  CATCATGGAG  GGTGGAGCCA  TGGTCCTGGC  TGATGGTGGG  1320
1321  GTCGTCTGTA  TTGACGAGTT  TGACAAGATG  CGAGAAGATG  ACCGTGTGGC  AATCCATGAA  1380
1381  GCCATGGAGC  AGCAGACCAT  CTCTATCGCC  AAGGCCGGGA  TCACCACTAC  CCTGAACTCA  1440
1441  CGCTGCTCCG  TCCTGGCTGC  TGCCAACTCA  GTGTTCGGCC  GCTGGGATGA  GACGAAGGGG  1500
1501  GAGGACAACA  TTGACTTCAT  GCCCACCATC  TTGTCGCGCT  TCGATATGAT  CTTCATTGTC  1560
1561  AAGGATGAGC  ACAATGAGGA  GAGGGATGTG  ATGCTGGCCA  AGCATGTCAT  CACTCTGCAC  1620
1621  GTGAGTGCAC  TGACACAGAC  ACAGGCTGTG  GAGGGCGAGA  TCGACCTGGC  CAAGCTGAAG  1680
1681  AAGTTTATTG  CCTACTGCCG  AGCGAAGTGT  GGCCCCCGGC  TCTCAGCAGA  GGCTGCAGAG  1740
1741  AAACTGAAGA  ACCGCTACAT  CATCATGCGC  AGTGGGGCCC  GTCAGCATGA  GAGGGACAGT  1800
1801  GACCGCCGCT  CCAGCATCCC  CATCACTGTG  CGGCAGCTGG  AGGCCATTGT  GCGCATCGCG  1860
1861  GAATCGCTCA  GCAAGATGAA  GCTGCAGCCC  TTCGCCACGG  AGGCAGATGT  GGAGGAGGCC  1920
1921  CTGCGGCTCT  TCCAAGTGTC  CACGTTGGAT  GCTGCCTTGT  CTGGTACCCT  GTCAGGAGTG  1980
1981  GAGGGCTTCA  CCAGCCAGGA  GGACCAGGAG  ATGCTGAGCC  GCATCGAGAA  GCAGCTCAAG  2040
2041  CGCCGCTTTG  CCATTGGCTC  CCAGGTGTCT  GAGCACAGCA  TCATCAAGGA  CTTCACCAAG  2100
2101  CAGAAATACC  CGGAGCACGC  CATCCACAAG  GTGCTGCAGC  TCATGCTGCG  GCGCGGCGAG  2160
2161  ATCCAGCATC  GCATGCAGCG  CAAGGTTCTC  TACCGCCTCA  AGTGA  2205

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-3206Papio anubis99.860.01513
LLPS-Mal-1055Mandrillus leucophaeus99.860.01513
LLPS-Mam-2158Macaca mulatta99.730.01511
LLPS-Maf-0332Macaca fascicularis99.730.01511
LLPS-Chs-0187Chlorocebus sabaeus99.590.01511
LLPS-Hos-0033Homo sapiens99.460.01508
LLPS-Pat-1238Pan troglodytes99.460.01508
LLPS-Rhb-0999Rhinopithecus bieti99.460.01507
LLPS-Pap-0843Pan paniscus99.320.01506
LLPS-Gog-1661Gorilla gorilla99.320.01504
LLPS-Caj-2478Callithrix jacchus99.320.01504
LLPS-Aon-0032Aotus nancymaae98.770.01497
LLPS-Otg-1833Otolemur garnettii98.230.01495
LLPS-Fec-1293Felis catus98.090.01495
LLPS-Caf-0456Canis familiaris98.030.01343
LLPS-Cas-2013Carlito syrichta97.820.01205
LLPS-Man-0169Macaca nemestrina97.710.01481
LLPS-Ict-2043Ictidomys tridecemlineatus97.680.01491
LLPS-Eqc-0667Equus caballus97.370.01215
LLPS-Orc-0823Oryctolagus cuniculus97.280.01487
LLPS-Aim-0199Ailuropoda melanoleuca97.280.01479
LLPS-Bot-0274Bos taurus97.140.01484
LLPS-Myl-0411Myotis lucifugus97.140.01480
LLPS-Loa-0099Loxodonta africana96.870.01476
LLPS-Fud-0526Fukomys damarensis96.310.01358
LLPS-Nol-2286Nomascus leucogenys95.640.01427
LLPS-Mum-0146Mus musculus95.640.01461
LLPS-Sus-0623Sus scrofa95.640.01442
LLPS-Urm-1163Ursus maritimus95.420.01314
LLPS-Ova-1513Ovis aries95.230.01402
LLPS-Dio-1829Dipodomys ordii95.10.01398
LLPS-Ran-0485Rattus norvegicus94.820.01455
LLPS-Cap-2673Cavia porcellus93.730.01414
LLPS-Poa-0568Pongo abelii93.60.01400
LLPS-Mod-1542Monodelphis domestica92.90.01372
LLPS-Mup-1044Mustela putorius furo91.980.01396
LLPS-Mea-0837Mesocricetus auratus90.60.01350
LLPS-Pes-0064Pelodiscus sinensis90.330.01410
LLPS-Anc-0637Anolis carolinensis88.420.01369
LLPS-Fia-1915Ficedula albicollis88.30.01363
LLPS-Gaga-1699Gallus gallus88.280.01382
LLPS-Tag-0525Taeniopygia guttata87.50.01263
LLPS-Xet-0434Xenopus tropicalis87.210.01368
LLPS-Anp-1401Anas platyrhynchos85.690.01254
LLPS-Asm-2826Astyanax mexicanus80.60.01257
LLPS-Icp-0659Ictalurus punctatus80.570.01260
LLPS-Dar-0077Danio rerio80.430.01263
LLPS-Scf-0001Scleropages formosus79.950.01259
LLPS-Orn-2418Oreochromis niloticus78.830.01229
LLPS-Scm-0358Scophthalmus maximus78.420.01229
LLPS-Pof-0225Poecilia formosa78.270.01220
LLPS-Orl-0567Oryzias latipes77.880.01220
LLPS-Tar-1261Takifugu rubripes77.340.01217
LLPS-Gaa-0363Gasterosteus aculeatus77.240.01190
LLPS-Xim-0760Xiphophorus maculatus73.440.01122
LLPS-Cii-0618Ciona intestinalis71.120.01134
LLPS-Drm-0837Drosophila melanogaster68.790.01073
LLPS-Lac-1647Latimeria chalumnae66.670.0 859
LLPS-Cae-0258Caenorhabditis elegans59.790.0 926
LLPS-Abg-0835Absidia glauca53.010.0 751
LLPS-Via-0648Vigna angularis52.760.0 624
LLPS-Ten-1155Tetraodon nigroviridis52.710.0 666
LLPS-Tum-0720Tuber melanosporum51.180.0 703
LLPS-Usm-0810Ustilago maydis50.80.0 722
LLPS-Trv-0189Trichoderma virens50.770.0 683
LLPS-Amt-0769Amborella trichopoda50.740.0 677
LLPS-Sob-0325Sorghum bicolor50.730.0 682
LLPS-Sei-0067Setaria italica50.60.0 687
LLPS-Asn-0042Aspergillus nidulans50.560.0 684
LLPS-Spr-0423Sporisorium reilianum50.530.0 708
LLPS-Zem-1728Zea mays50.530.0 673
LLPS-Asc-0049Aspergillus clavatus50.480.0 681
LLPS-Trr-0651Trichoderma reesei50.410.0 683
LLPS-Asfu-0955Aspergillus fumigatus50.340.0 686
LLPS-Cogr-0626Colletotrichum graminicola50.340.0 692
LLPS-Prp-0640Prunus persica50.330.0 692
LLPS-Org-0659Oryza glaberrima50.330.0 680
LLPS-Ors-1468Oryza sativa50.330.0 680
LLPS-Ori-0310Oryza indica50.330.0 679
LLPS-Put-0165Puccinia triticina50.280.0 680
LLPS-Tra-0902Triticum aestivum50.270.0 673
LLPS-Asni-0228Aspergillus niger50.210.0 679
LLPS-Cus-1181Cucumis sativus50.20.0 684
LLPS-Crn-0185Cryptococcus neoformans50.20.0 703
LLPS-Ved-0073Verticillium dahliae50.140.0 691
LLPS-Coo-0417Colletotrichum orbiculare50.140.0 697
LLPS-Mao-0643Magnaporthe oryzae50.140.0 690
LLPS-Orbr-0113Oryza brachyantha50.00.0 681
LLPS-Brd-1596Brachypodium distachyon50.00.0 675
LLPS-Cog-0987Colletotrichum gloeosporioides49.930.0 701
LLPS-Gag-0313Gaeumannomyces graminis49.930.0 689
LLPS-Nef-0217Neosartorya fischeri49.860.0 681
LLPS-Hea-0489Helianthus annuus49.80.0 666
LLPS-Pug-0293Puccinia graminis49.790.0 684
LLPS-Pot-0829Populus trichocarpa49.730.0 678
LLPS-Beb-0268Beauveria bassiana49.730.0 658
LLPS-Thc-1354Theobroma cacao49.730.0 676
LLPS-Aso-1338Aspergillus oryzae49.720.0 678
LLPS-Asf-0648Aspergillus flavus49.720.0 678
LLPS-Ast-0359Aspergillus terreus49.660.0 676
LLPS-Coc-1791Corchorus capsularis49.650.0 655
LLPS-Miv-0561Microbotryum violaceum49.540.0 690
LLPS-Met-1939Medicago truncatula49.530.0 671
LLPS-Fus-0508Fusarium solani49.520.0 669
LLPS-Mel-0737Melampsora laricipopulina49.520.0 691
LLPS-Mua-0556Musa acuminata49.40.0 672
LLPS-Scc-0150Schizosaccharomyces cryophilus49.390.0 670
LLPS-Php-0532Physcomitrella patens49.390.0 674
LLPS-Sem-0683Selaginella moellendorffii49.330.0 668
LLPS-Phn-0276Phaeosphaeria nodorum49.320.0 686
LLPS-Brr-0267Brassica rapa49.260.0 671
LLPS-Map-0424Magnaporthe poae49.240.0 674
LLPS-Fuo-0336Fusarium oxysporum49.21e-142 434
LLPS-Blg-0507Blumeria graminis49.160.0 656
LLPS-Lep-0038Leersia perrieri49.140.0 649
LLPS-Viv-0857Vitis vinifera49.130.0 673
LLPS-Phv-0045Phaseolus vulgaris49.130.0 673
LLPS-Dac-0770Daucus carota49.060.0 660
LLPS-Orp-0461Oryza punctata49.00.0 650
LLPS-Bro-0003Brassica oleracea48.990.0 668
LLPS-Brn-1588Brassica napus48.990.0 668
LLPS-Scj-0252Schizosaccharomyces japonicus48.980.0 668
LLPS-Gor-0672Gossypium raimondii48.930.0 675
LLPS-Nec-0302Neurospora crassa48.920.0 671
LLPS-Pyt-0658Pyrenophora teres48.830.0 666
LLPS-Mae-0542Manihot esculenta48.790.0 668
LLPS-Art-0486Arabidopsis thaliana48.710.0 665
LLPS-Pytr-0323Pyrenophora triticirepentis48.690.0 667
LLPS-Nia-0288Nicotiana attenuata48.670.0 668
LLPS-Lem-0441Leptosphaeria maculans48.640.0 657
LLPS-Arl-0158Arabidopsis lyrata48.460.0 662
LLPS-Glm-1558Glycine max48.320.0 666
LLPS-Fuv-0076Fusarium verticillioides48.30.0 642
LLPS-Asg-0733Ashbya gossypii48.260.0 665
LLPS-Vir-0698Vigna radiata48.130.0 664
LLPS-Tru-0215Triticum urartu47.830.0 583
LLPS-Scp-0385Schizosaccharomyces pombe47.760.0 662
LLPS-Dos-0101Dothistroma septosporum47.690.0 673
LLPS-Orr-1983Oryza rufipogon47.670.0 618
LLPS-Orgl-1399Oryza glumaepatula47.670.0 618
LLPS-Orb-1406Oryza barthii47.670.0 618
LLPS-Orni-1663Oryza nivara47.670.0 618
LLPS-Sot-0113Solanum tuberosum47.460.0 657
LLPS-Zyt-0306Zymoseptoria tritici47.070.0 647
LLPS-Sac-1168Saccharomyces cerevisiae46.990.0 665
LLPS-Orm-0520Oryza meridionalis46.920.0 611
LLPS-Yal-0471Yarrowia lipolytica46.90.0 641
LLPS-Kop-0415Komagataella pastoris46.110.0 640
LLPS-Gas-0728Galdieria sulphuraria46.070.0 639
LLPS-Osl-0870Ostreococcus lucimarinus45.630.0 586
LLPS-Cym-0114Cyanidioschyzon merolae45.490.0 607
LLPS-Chc-0382Chondrus crispus43.480.0 619
LLPS-Chr-0122Chlamydomonas reinhardtii43.10.0 556
LLPS-Sol-0317Solanum lycopersicum35.025e-104 344
LLPS-Hov-0941Hordeum vulgare34.857e-108 355