LLPS-Cas-2149
DYRK1B
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1 |
| Gene Name: | DYRK1B |
| Ensembl Gene: | ENSTSYG00000037028.1 |
| Ensembl Protein: | ENSTSYP00000033500.1 |
| Organism: | Carlito syrichta |
| Taxa ID: | 1868482 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTSYT00000030974.1 | ENSTSYP00000033500.1 |
| Ensembl | ENSTSYT00000036066.1 | ENSTSYP00000020161.1 |
| UniProt | A0A1U7T575, A0A1U7T575_TARSY | |
| RefSeq | , XM_008054759.1, XM_021710705.1 | , XP_008052950.1, XP_021566380.1, XP_008052950.1, XP_021566380.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAVPPGHGPF SGFPGPQEHT QVLPDVRLLP RRLPLAFRDS TSAPLRKLSV DLIKTYKHIN 60 61 EVYYAKKKRR AQQAPPQDSS TKKEKKVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG 120 121 SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF 180 181 MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL 240 241 KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG 300 301 CILVEMHTGE PLFSGSNEVD QMNRIVEVLG IPPAPMLDQA PKARKYFERL PGGGWTLRRT 360 361 KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPASRI 420 421 SPLGALQHGF FRRTADEATN TGPAGSSAST SPAPLDTCPS SSTASSISSS GGSSGSSSDN 480 481 RTYRYSNRYC GGPGPPITDC EMNSPQVPPS QPLRPWAGGD VPHKTHQAPT SASSLPGTGA 540 541 QLPPQPRCLG RPPSPTSPPP PELMDVSLVG GPPDCSPPHP APAPQHPAAS ALRTRMTGGR 600 601 PPLPPPDDPA TLGPRLGLRG VPQSTAASS 629 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCGTCC CACCGGGCCA TGGTCCCTTC TCTGGCTTTC CAGGGCCCCA GGAGCACACG 60 61 CAGGTATTGC CTGATGTGCG GCTGCTGCCT CGAAGGCTGC CCTTGGCCTT CCGGGACTCA 120 121 ACCTCAGCCC CCCTGCGTAA GCTCTCTGTG GACCTCATCA AGACCTACAA GCACATCAAT 180 181 GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAGCAGG CGCCACCCCA GGACTCGAGC 240 241 ACCAAGAAGG AGAAGAAGGT CTTGAACCAT GGTTATGATG ACGACAACCA TGACTACATC 300 301 GTGCGCAGTG GCGAGCGCTG GCTGGAGCGC TACGAGATTG ACTCGCTCAT TGGCAAAGGC 360 361 TCCTTTGGCC AGGTGGTGAA AGCCTATGAC CATCAGACCC AGGAGTTGGT GGCCATCAAG 420 421 ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCCCAGA TTGAGCTGCG GCTGCTGGAG 480 481 CTGATGAACC AGCATGACAC AGAGATGAAG TACTATATAG TGCACCTGAA GCGGCACTTC 540 541 ATGTTCCGGA ACCACCTGTG CCTGGTGTTC GAGCTGCTGT CCTACAACCT GTATGACCTC 600 601 CTGCGCAACA CACACTTCCG AGGCGTCTCG CTGAACCTGA CCCGGAAGCT AGCGCAGCAG 660 661 CTCTGCACAG CGCTGCTCTT CTTGGCCACG CCTGAGCTTA GCATCATTCA CTGCGACCTC 720 721 AAGCCGGAGA ACATTCTACT CTGCAACCCC AAGCGCAGCG CCATCAAGAT CGTGGACTTC 780 781 GGCAGCTCCT GCCAACTTGG CCAGCGGATC TACCAGTATA TCCAGAGTCG CTTCTACCGC 840 841 TCACCCGAGG TGCTCCTGGG CACACCCTAC GACCTGGCCA TCGACATGTG GTCCCTGGGC 900 901 TGTATCCTTG TGGAGATGCA CACTGGAGAG CCCCTCTTCA GTGGCTCCAA TGAGGTGGAC 960 961 CAGATGAACC GCATTGTGGA GGTGCTGGGC ATCCCACCAG CCCCCATGCT GGACCAGGCA 1020 1021 CCCAAGGCTC GCAAGTACTT TGAACGGCTG CCTGGGGGTG GCTGGACCCT GCGAAGGACA 1080 1081 AAGGAACTCA GGAAGGATTA CCAGGGCCCC GGGACACGGC GGCTGCAGGA GGTGCTGGGC 1140 1141 GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 1200 1201 TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CTCCCGCATC 1260 1261 AGCCCGCTGG GGGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 1320 1321 ACGGGCCCGG CAGGCAGCAG TGCCTCCACT TCGCCCGCAC CCCTCGACAC CTGCCCATCC 1380 1381 TCCAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGTTCCA GTGGCTCCTC CAGTGACAAC 1440 1441 CGGACCTACC GCTACAGCAA CCGATATTGT GGGGGCCCGG GGCCCCCTAT CACTGACTGT 1500 1501 GAGATGAACA GCCCCCAGGT CCCCCCCTCC CAGCCGCTAC GCCCCTGGGC AGGGGGTGAT 1560 1561 GTGCCCCACA AGACACATCA AGCCCCTACC TCTGCCTCAT CACTGCCGGG GACCGGGGCC 1620 1621 CAGTTACCCC CCCAGCCCCG ATGCCTTGGC CGACCCCCAT CGCCAACCTC ACCACCACCC 1680 1681 CCGGAGCTGA TGGATGTGAG CCTAGTGGGC GGCCCTCCAG ACTGCTCCCC GCCTCACCCA 1740 1741 GCGCCTGCCC CTCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC AGGAGGTCGT 1800 1801 CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGCCTGGG CCTCCGTGGT 1860 1861 GTACCCCAGA GCACTGCAGC CAGCTCATGA 1890 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ict-0556 | Ictidomys tridecemlineatus | 99.35 | 0.0 | 991 |
| LLPS-Otg-3228 | Otolemur garnettii | 99.18 | 0.0 | 992 |
| LLPS-Sus-3966 | Sus scrofa | 99.18 | 0.0 | 989 |
| LLPS-Pap-3590 | Pan paniscus | 99.14 | 0.0 | 682 |
| LLPS-Rhb-0337 | Rhinopithecus bieti | 98.86 | 0.0 | 988 |
| LLPS-Man-1452 | Macaca nemestrina | 98.69 | 0.0 | 985 |
| LLPS-Hos-4712 | Homo sapiens | 98.69 | 0.0 | 985 |
| LLPS-Pat-0588 | Pan troglodytes | 98.69 | 0.0 | 985 |
| LLPS-Cea-0710 | Cercocebus atys | 98.69 | 0.0 | 985 |
| LLPS-Maf-2171 | Macaca fascicularis | 98.69 | 0.0 | 985 |
| LLPS-Bot-0121 | Bos taurus | 98.55 | 0.0 | 959 |
| LLPS-Paa-4037 | Papio anubis | 98.53 | 0.0 | 983 |
| LLPS-Mal-4723 | Mandrillus leucophaeus | 98.53 | 0.0 | 982 |
| LLPS-Myl-2138 | Myotis lucifugus | 98.11 | 0.0 | 958 |
| LLPS-Mum-4913 | Mus musculus | 97.72 | 0.0 | 974 |
| LLPS-Mea-0904 | Mesocricetus auratus | 97.72 | 0.0 | 972 |
| LLPS-Dio-2673 | Dipodomys ordii | 97.55 | 0.0 | 976 |
| LLPS-Nol-3806 | Nomascus leucogenys | 96.46 | 0.0 | 699 |
| LLPS-Cap-4161 | Cavia porcellus | 96.25 | 0.0 | 939 |
| LLPS-Ten-1420 | Tetraodon nigroviridis | 96.15 | 4e-132 | 393 |
| LLPS-Aim-0305 | Ailuropoda melanoleuca | 94.95 | 0.0 | 932 |
| LLPS-Fec-2237 | Felis catus | 94.78 | 0.0 | 950 |
| LLPS-Eqc-1515 | Equus caballus | 94.29 | 0.0 | 943 |
| LLPS-Fud-2143 | Fukomys damarensis | 94.29 | 0.0 | 938 |
| LLPS-Mam-4134 | Macaca mulatta | 94.13 | 0.0 | 943 |
| LLPS-Gog-1232 | Gorilla gorilla | 94.13 | 0.0 | 942 |
| LLPS-Poa-0252 | Pongo abelii | 93.8 | 0.0 | 941 |
| LLPS-Mod-0654 | Monodelphis domestica | 93.71 | 0.0 | 861 |
| LLPS-Ran-4881 | Rattus norvegicus | 93.64 | 0.0 | 932 |
| LLPS-Caf-4072 | Canis familiaris | 92.5 | 0.0 | 920 |
| LLPS-Mup-3455 | Mustela putorius furo | 92.33 | 0.0 | 913 |
| LLPS-Chs-3772 | Chlorocebus sabaeus | 92.17 | 0.0 | 915 |
| LLPS-Caj-4133 | Callithrix jacchus | 92.01 | 0.0 | 907 |
| LLPS-Urm-1713 | Ursus maritimus | 90.86 | 0.0 | 910 |
| LLPS-Aon-4132 | Aotus nancymaae | 90.02 | 0.0 | 923 |
| LLPS-Xet-3463 | Xenopus tropicalis | 86.06 | 0.0 | 575 |
| LLPS-Pes-3766 | Pelodiscus sinensis | 85.04 | 0.0 | 646 |
| LLPS-Loa-2162 | Loxodonta africana | 83.22 | 0.0 | 788 |
| LLPS-Gaga-3630 | Gallus gallus | 82.84 | 0.0 | 660 |
| LLPS-Tut-1032 | Tursiops truncatus | 82.84 | 0.0 | 657 |
| LLPS-Meg-1660 | Meleagris gallopavo | 82.59 | 0.0 | 658 |
| LLPS-Tag-0956 | Taeniopygia guttata | 82.34 | 0.0 | 656 |
| LLPS-Fia-3019 | Ficedula albicollis | 82.34 | 0.0 | 656 |
| LLPS-Ora-0632 | Ornithorhynchus anatinus | 82.34 | 0.0 | 656 |
| LLPS-Scm-0042 | Scophthalmus maximus | 82.04 | 0.0 | 643 |
| LLPS-Pof-2737 | Poecilia formosa | 82.04 | 0.0 | 647 |
| LLPS-Orn-0624 | Oreochromis niloticus | 82.04 | 0.0 | 644 |
| LLPS-Gaa-0601 | Gasterosteus aculeatus | 82.04 | 0.0 | 647 |
| LLPS-Tar-3086 | Takifugu rubripes | 82.04 | 0.0 | 643 |
| LLPS-Xim-2729 | Xiphophorus maculatus | 82.04 | 0.0 | 642 |
| LLPS-Orl-2928 | Oryzias latipes | 82.04 | 0.0 | 643 |
| LLPS-Scf-0831 | Scleropages formosus | 81.55 | 0.0 | 645 |
| LLPS-Icp-0651 | Ictalurus punctatus | 81.55 | 0.0 | 666 |
| LLPS-Asm-1662 | Astyanax mexicanus | 81.3 | 0.0 | 664 |
| LLPS-Anp-0518 | Anas platyrhynchos | 80.85 | 0.0 | 637 |
| LLPS-Dar-2011 | Danio rerio | 80.55 | 0.0 | 660 |
| LLPS-Anc-0036 | Anolis carolinensis | 79.56 | 0.0 | 734 |
| LLPS-Leo-3574 | Lepisosteus oculatus | 78.64 | 0.0 | 696 |
| LLPS-Drm-1474 | Drosophila melanogaster | 77.17 | 0.0 | 622 |
| LLPS-Cii-0267 | Ciona intestinalis | 73.95 | 0.0 | 607 |
| LLPS-Ova-1692 | Ovis aries | 73.52 | 0.0 | 661 |
| LLPS-Lac-1519 | Latimeria chalumnae | 73.42 | 0.0 | 659 |
| LLPS-Orc-1489 | Oryctolagus cuniculus | 73.32 | 0.0 | 660 |
| LLPS-Sah-2509 | Sarcophilus harrisii | 73.12 | 0.0 | 657 |
| LLPS-Cae-0669 | Caenorhabditis elegans | 66.09 | 5e-147 | 455 |
| LLPS-Phn-0404 | Phaeosphaeria nodorum | 48.26 | 4e-85 | 291 |
| LLPS-Fus-0588 | Fusarium solani | 48.26 | 3e-85 | 290 |
| LLPS-Pyt-1023 | Pyrenophora teres | 48.26 | 8e-86 | 293 |
| LLPS-Nec-1368 | Neurospora crassa | 48.26 | 2e-84 | 290 |
| LLPS-Asc-0705 | Aspergillus clavatus | 48.26 | 9e-86 | 293 |
| LLPS-Asn-1449 | Aspergillus nidulans | 48.26 | 2e-85 | 292 |
| LLPS-Fuo-1512 | Fusarium oxysporum | 47.95 | 4e-84 | 289 |
| LLPS-Trv-1257 | Trichoderma virens | 47.95 | 2e-84 | 288 |
| LLPS-Cogr-1421 | Colletotrichum graminicola | 47.95 | 3e-84 | 289 |
| LLPS-Ast-0116 | Aspergillus terreus | 47.95 | 1e-84 | 290 |
| LLPS-Trr-0640 | Trichoderma reesei | 47.95 | 4e-84 | 287 |
| LLPS-Asni-0963 | Aspergillus niger | 47.95 | 9e-85 | 290 |
| LLPS-Fuv-1271 | Fusarium verticillioides | 47.78 | 3e-84 | 289 |
| LLPS-Chr-1349 | Chlamydomonas reinhardtii | 46.47 | 7e-91 | 311 |
| LLPS-Cis-1203 | Ciona savignyi | 45.3 | 8e-91 | 293 |
| LLPS-Crn-0948 | Cryptococcus neoformans | 44.06 | 9e-90 | 310 |
| LLPS-Put-0441 | Puccinia triticina | 43.82 | 4e-86 | 300 |
| LLPS-Miv-1213 | Microbotryum violaceum | 43.39 | 3e-86 | 302 |
| LLPS-Sem-0330 | Selaginella moellendorffii | 42.98 | 2e-84 | 276 |
| LLPS-Abg-1599 | Absidia glauca | 42.58 | 3e-88 | 303 |
| LLPS-Scc-1083 | Schizosaccharomyces cryophilus | 42.57 | 5e-88 | 291 |
| LLPS-Scp-1587 | Schizosaccharomyces pombe | 42.44 | 1e-86 | 286 |
| LLPS-Aso-1071 | Aspergillus oryzae | 41.98 | 2e-86 | 286 |
| LLPS-Nef-0376 | Neosartorya fischeri | 41.85 | 1e-85 | 293 |
| LLPS-Asf-1235 | Aspergillus flavus | 41.85 | 1e-85 | 293 |
| LLPS-Tum-1580 | Tuber melanosporum | 41.77 | 8e-87 | 296 |
| LLPS-Blg-0482 | Blumeria graminis | 41.74 | 2e-84 | 293 |
| LLPS-Ere-0389 | Erinaceus europaeus | 40.72 | 7e-85 | 282 |
| LLPS-Pytr-0816 | Pyrenophora triticirepentis | 38.38 | 1e-84 | 282 |