LLPS-Cas-1995
GRPEL1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | GrpE protein homolog |
| Gene Name: | GRPEL1 |
| Ensembl Gene: | ENSTSYG00000030771.1 |
| Ensembl Protein: | ENSTSYP00000021538.1 |
| Organism: | Carlito syrichta |
| Taxa ID: | 1868482 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTSYT00000044316.1 | ENSTSYP00000021538.1 |
| UniProt | A0A1U7T3D3, A0A1U7T3D3_TARSY | |
| RefSeq | , XM_008050185.1 | , XP_008048376.1, XP_008048376.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAARCVRLAR RSLPALTLSL RSSPRLLCTA AKQKNNGQNL EEDTGPNEQK SDPPATEKVL 60 61 LEEKVKLEEQ LKETVEKYKR ALADTENLRQ RSQKLVEEAK LYGIQAFCKD LLEVADILEK 120 121 ATQCVPKEEV KDDNPHLKSL YEGLVMTEVQ IQKVFTKHGL LRLNPVGAKF NPYEHEALFH 180 181 TPVEGKEPGT VALVSKVGYK LHGRTLRPAL VGVVKEA 217 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCTC GGTGTGTGAG GTTGGCGAGG CGCAGTCTCC CGGCGTTGAC GCTGTCGCTC 60 61 AGGTCCTCTC CTCGGCTGTT GTGCACAGCT GCAAAACAAA AGAACAATGG CCAGAACTTG 120 121 GAAGAAGACA CGGGCCCAAA TGAACAGAAG TCAGATCCTC CTGCCACAGA GAAGGTTCTC 180 181 CTGGAAGAGA AGGTCAAGTT AGAAGAGCAG CTGAAAGAGA CTGTGGAAAA ATATAAACGC 240 241 GCTTTGGCAG ATACTGAGAA CTTGCGGCAG AGAAGCCAAA AATTGGTGGA GGAGGCAAAA 300 301 TTATATGGCA TTCAGGCATT CTGCAAGGAC TTGTTGGAGG TGGCAGACAT TTTGGAGAAG 360 361 GCCACACAAT GTGTTCCCAA GGAAGAAGTT AAAGACGACA ACCCTCACTT GAAGAGCCTC 420 421 TATGAGGGGC TGGTCATGAC TGAGGTCCAG ATCCAGAAGG TGTTCACCAA GCACGGCCTG 480 481 CTCAGGTTGA ACCCCGTGGG AGCCAAGTTC AACCCGTACG AACACGAGGC CTTGTTCCAC 540 541 ACACCAGTGG AGGGGAAGGA GCCGGGCACG GTGGCACTCG TCAGCAAGGT GGGGTACAAG 600 601 CTGCACGGGC GCACGCTGAG ACCGGCCCTG GTGGGGGTGG TGAAGGAGGC CTAG 654 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial matrix | |
Cellular Component | Nucleus | |
Molecular Function | Adenyl-nucleotide exchange factor activity | |
Molecular Function | Chaperone binding | |
Molecular Function | Protein homodimerization activity | |
Molecular Function | Unfolded protein binding | |
Biological Process | Protein folding |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Otg-1859 | Otolemur garnettii | 94.01 | 2e-112 | 328 |
| LLPS-Hos-1114 | Homo sapiens | 93.09 | 5e-112 | 327 |
| LLPS-Pat-1557 | Pan troglodytes | 93.09 | 5e-112 | 327 |
| LLPS-Pap-3232 | Pan paniscus | 93.09 | 5e-112 | 327 |
| LLPS-Man-4466 | Macaca nemestrina | 93.09 | 5e-112 | 327 |
| LLPS-Paa-1929 | Papio anubis | 93.09 | 4e-112 | 327 |
| LLPS-Gog-2233 | Gorilla gorilla | 93.09 | 5e-112 | 327 |
| LLPS-Chs-4798 | Chlorocebus sabaeus | 93.09 | 5e-112 | 327 |
| LLPS-Maf-1847 | Macaca fascicularis | 93.09 | 5e-112 | 327 |
| LLPS-Cea-0513 | Cercocebus atys | 93.09 | 4e-112 | 327 |
| LLPS-Nol-4617 | Nomascus leucogenys | 92.63 | 2e-111 | 325 |
| LLPS-Rhb-4529 | Rhinopithecus bieti | 92.17 | 3e-111 | 325 |
| LLPS-Loa-4483 | Loxodonta africana | 92.11 | 3e-108 | 317 |
| LLPS-Eqc-3885 | Equus caballus | 91.71 | 3e-112 | 327 |
| LLPS-Ova-4489 | Ovis aries | 91.71 | 2e-111 | 325 |
| LLPS-Fec-1825 | Felis catus | 91.24 | 2e-109 | 320 |
| LLPS-Mal-2759 | Mandrillus leucophaeus | 91.24 | 2e-110 | 322 |
| LLPS-Bot-3944 | Bos taurus | 91.24 | 4e-111 | 324 |
| LLPS-Caj-1678 | Callithrix jacchus | 91.24 | 3e-111 | 325 |
| LLPS-Aon-3123 | Aotus nancymaae | 91.24 | 3e-112 | 327 |
| LLPS-Aim-4067 | Ailuropoda melanoleuca | 90.78 | 2e-109 | 320 |
| LLPS-Caf-1390 | Canis familiaris | 89.86 | 1e-106 | 313 |
| LLPS-Fud-1947 | Fukomys damarensis | 89.47 | 9e-105 | 308 |
| LLPS-Ran-1463 | Rattus norvegicus | 88.95 | 2e-102 | 303 |
| LLPS-Tut-2080 | Tursiops truncatus | 88.48 | 5e-108 | 317 |
| LLPS-Dio-1573 | Dipodomys ordii | 88.42 | 2e-106 | 312 |
| LLPS-Ict-2617 | Ictidomys tridecemlineatus | 88.02 | 1e-106 | 313 |
| LLPS-Cap-3969 | Cavia porcellus | 88.02 | 2e-107 | 315 |
| LLPS-Mum-3432 | Mus musculus | 87.56 | 2e-105 | 310 |
| LLPS-Myl-2620 | Myotis lucifugus | 87.37 | 4e-104 | 306 |
| LLPS-Mea-2099 | Mesocricetus auratus | 87.1 | 2e-104 | 307 |
| LLPS-Urm-3328 | Ursus maritimus | 85.25 | 2e-107 | 315 |
| LLPS-Mup-1599 | Mustela putorius furo | 84.79 | 3e-102 | 302 |
| LLPS-Sus-2688 | Sus scrofa | 84.79 | 1e-101 | 300 |
| LLPS-Sah-2249 | Sarcophilus harrisii | 84.26 | 3e-103 | 305 |
| LLPS-Scf-1897 | Scleropages formosus | 84.06 | 7e-80 | 243 |
| LLPS-Mod-2455 | Monodelphis domestica | 83.8 | 6e-102 | 301 |
| LLPS-Ora-1368 | Ornithorhynchus anatinus | 82.95 | 2e-101 | 300 |
| LLPS-Ere-0220 | Erinaceus europaeus | 82.46 | 8e-66 | 205 |
| LLPS-Gaga-0374 | Gallus gallus | 82.29 | 2e-99 | 295 |
| LLPS-Meg-2061 | Meleagris gallopavo | 82.29 | 3e-99 | 294 |
| LLPS-Tag-0368 | Taeniopygia guttata | 81.77 | 8e-97 | 288 |
| LLPS-Anp-1472 | Anas platyrhynchos | 80.73 | 6e-95 | 283 |
| LLPS-Fia-3081 | Ficedula albicollis | 79.69 | 3e-96 | 286 |
| LLPS-Pes-1359 | Pelodiscus sinensis | 79.17 | 7e-92 | 275 |
| LLPS-Pof-1886 | Poecilia formosa | 78.19 | 1e-82 | 252 |
| LLPS-Leo-2442 | Lepisosteus oculatus | 78.19 | 7e-88 | 265 |
| LLPS-Xim-3075 | Xiphophorus maculatus | 77.66 | 2e-82 | 251 |
| LLPS-Anc-2361 | Anolis carolinensis | 75.92 | 8e-88 | 265 |
| LLPS-Icp-2749 | Ictalurus punctatus | 75.0 | 1e-82 | 252 |
| LLPS-Lac-3200 | Latimeria chalumnae | 74.89 | 8e-93 | 278 |
| LLPS-Orn-3810 | Oreochromis niloticus | 73.94 | 1e-83 | 254 |
| LLPS-Dar-1204 | Danio rerio | 73.94 | 3e-85 | 259 |
| LLPS-Orl-1662 | Oryzias latipes | 73.94 | 2e-80 | 248 |
| LLPS-Scm-3915 | Scophthalmus maximus | 72.87 | 5e-81 | 248 |
| LLPS-Tar-1362 | Takifugu rubripes | 72.34 | 4e-81 | 248 |
| LLPS-Xet-1119 | Xenopus tropicalis | 71.81 | 9e-83 | 252 |
| LLPS-Gaa-1709 | Gasterosteus aculeatus | 70.74 | 1e-78 | 242 |
| LLPS-Asm-1970 | Astyanax mexicanus | 70.05 | 1e-81 | 249 |
| LLPS-Drm-2346 | Drosophila melanogaster | 56.52 | 4e-47 | 160 |
| LLPS-Poa-2235 | Pongo abelii | 55.26 | 5e-47 | 160 |
| LLPS-Cii-1604 | Ciona intestinalis | 53.52 | 3e-47 | 161 |
| LLPS-Cis-1168 | Ciona savignyi | 52.14 | 2e-46 | 159 |
| LLPS-Fuo-0015 | Fusarium oxysporum | 49.65 | 1e-33 | 127 |
| LLPS-Php-0492 | Physcomitrella patens | 49.65 | 2e-34 | 130 |
| LLPS-Fuv-0312 | Fusarium verticillioides | 49.65 | 1e-33 | 127 |
| LLPS-Beb-1253 | Beauveria bassiana | 48.95 | 3e-34 | 128 |
| LLPS-Trv-0705 | Trichoderma virens | 47.55 | 3e-33 | 125 |
| LLPS-Trr-1555 | Trichoderma reesei | 47.55 | 4e-33 | 125 |
| LLPS-Fus-1396 | Fusarium solani | 47.52 | 1e-32 | 124 |
| LLPS-Nec-0949 | Neurospora crassa | 47.52 | 1e-32 | 124 |
| LLPS-Cae-0441 | Caenorhabditis elegans | 46.76 | 3e-36 | 133 |
| LLPS-Coc-1541 | Corchorus capsularis | 46.48 | 4e-15 | 72.8 |
| LLPS-Osl-0441 | Ostreococcus lucimarinus | 46.1 | 6e-34 | 127 |
| LLPS-Scj-0235 | Schizosaccharomyces japonicus | 45.71 | 1e-30 | 117 |
| LLPS-Gas-1216 | Galdieria sulphuraria | 45.65 | 6e-31 | 120 |
| LLPS-Scs-0648 | Sclerotinia sclerotiorum | 45.52 | 3e-30 | 117 |
| LLPS-Sei-0419 | Setaria italica | 45.45 | 2e-29 | 116 |
| LLPS-Ved-0919 | Verticillium dahliae | 45.21 | 3e-30 | 117 |
| LLPS-Tru-0929 | Triticum urartu | 45.07 | 6e-29 | 114 |
| LLPS-Sob-1768 | Sorghum bicolor | 45.07 | 7e-29 | 115 |
| LLPS-Cog-0858 | Colletotrichum gloeosporioides | 44.76 | 3e-32 | 122 |
| LLPS-Tra-0082 | Triticum aestivum | 44.76 | 1e-28 | 114 |
| LLPS-Zem-0863 | Zea mays | 44.37 | 7e-29 | 115 |
| LLPS-Orbr-1232 | Oryza brachyantha | 44.37 | 7e-29 | 115 |
| LLPS-Pot-2084 | Populus trichocarpa | 44.14 | 5e-31 | 122 |
| LLPS-Chr-0127 | Chlamydomonas reinhardtii | 44.14 | 1e-28 | 114 |
| LLPS-Orp-1447 | Oryza punctata | 44.06 | 3e-29 | 116 |
| LLPS-Brd-1397 | Brachypodium distachyon | 44.06 | 2e-28 | 114 |
| LLPS-Orc-2668 | Oryctolagus cuniculus | 43.98 | 7e-43 | 150 |
| LLPS-Scp-1569 | Schizosaccharomyces pombe | 43.88 | 9e-33 | 124 |
| LLPS-Hov-2195 | Hordeum vulgare | 43.75 | 4e-28 | 113 |
| LLPS-Scc-1592 | Schizosaccharomyces cryophilus | 43.38 | 1e-31 | 120 |
| LLPS-Cogr-0345 | Colletotrichum graminicola | 43.36 | 1e-31 | 121 |
| LLPS-Org-0526 | Oryza glaberrima | 43.36 | 1e-28 | 114 |
| LLPS-Orr-0974 | Oryza rufipogon | 43.36 | 1e-28 | 114 |
| LLPS-Ors-0632 | Oryza sativa | 43.36 | 1e-28 | 114 |
| LLPS-Orgl-0916 | Oryza glumaepatula | 43.36 | 1e-28 | 114 |
| LLPS-Lep-0819 | Leersia perrieri | 43.36 | 5e-29 | 115 |
| LLPS-Coo-0040 | Colletotrichum orbiculare | 43.36 | 9e-29 | 113 |
| LLPS-Orni-1838 | Oryza nivara | 43.36 | 1e-28 | 114 |
| LLPS-Ori-1915 | Oryza indica | 43.36 | 1e-28 | 114 |
| LLPS-Orb-0237 | Oryza barthii | 43.36 | 1e-28 | 114 |
| LLPS-Lem-0979 | Leptosphaeria maculans | 42.96 | 2e-30 | 117 |
| LLPS-Thc-0615 | Theobroma cacao | 42.76 | 9e-28 | 112 |
| LLPS-Sem-1775 | Selaginella moellendorffii | 42.75 | 5e-25 | 101 |
| LLPS-Orm-2086 | Oryza meridionalis | 42.66 | 4e-28 | 113 |
| LLPS-Mae-2039 | Manihot esculenta | 42.47 | 5e-30 | 118 |
| LLPS-Met-2602 | Medicago truncatula | 42.47 | 2e-27 | 111 |
| LLPS-Hea-0968 | Helianthus annuus | 42.47 | 1e-29 | 117 |
| LLPS-Cus-1028 | Cucumis sativus | 42.36 | 3e-27 | 110 |
| LLPS-Mua-2461 | Musa acuminata | 42.36 | 1e-28 | 114 |
| LLPS-Chc-0914 | Chondrus crispus | 42.34 | 3e-29 | 114 |
| LLPS-Tum-1316 | Tuber melanosporum | 42.31 | 1e-29 | 116 |
| LLPS-Asfu-1622 | Aspergillus fumigatus | 42.28 | 7e-27 | 108 |
| LLPS-Pyt-0861 | Pyrenophora teres | 42.25 | 1e-30 | 118 |
| LLPS-Bro-2629 | Brassica oleracea | 41.96 | 6e-27 | 110 |
| LLPS-Usm-1507 | Ustilago maydis | 41.84 | 6e-27 | 108 |
| LLPS-Spr-1365 | Sporisorium reilianum | 41.84 | 6e-27 | 108 |
| LLPS-Mao-0264 | Magnaporthe oryzae | 41.83 | 4e-31 | 120 |
| LLPS-Art-2147 | Arabidopsis thaliana | 41.67 | 6e-27 | 109 |
| LLPS-Viv-2171 | Vitis vinifera | 41.67 | 7e-28 | 112 |
| LLPS-Nef-1202 | Neosartorya fischeri | 41.61 | 2e-26 | 107 |
| LLPS-Map-1010 | Magnaporthe poae | 41.61 | 1e-30 | 119 |
| LLPS-Pytr-0084 | Pyrenophora triticirepentis | 41.55 | 7e-30 | 116 |
| LLPS-Blg-1460 | Blumeria graminis | 41.5 | 8e-28 | 111 |
| LLPS-Vir-1319 | Vigna radiata | 41.38 | 7e-28 | 112 |
| LLPS-Via-1712 | Vigna angularis | 41.38 | 4e-28 | 113 |
| LLPS-Glm-2271 | Glycine max | 41.38 | 5e-28 | 112 |
| LLPS-Dac-1248 | Daucus carota | 41.26 | 1e-27 | 111 |
| LLPS-Gag-1532 | Gaeumannomyces graminis | 41.26 | 9e-31 | 119 |
| LLPS-Brn-0717 | Brassica napus | 41.26 | 2e-26 | 108 |
| LLPS-Gor-2450 | Gossypium raimondii | 40.97 | 2e-26 | 108 |
| LLPS-Arl-2859 | Arabidopsis lyrata | 40.97 | 3e-26 | 108 |
| LLPS-Asn-1508 | Aspergillus nidulans | 40.94 | 2e-25 | 104 |
| LLPS-Sol-0136 | Solanum lycopersicum | 40.85 | 5e-26 | 107 |
| LLPS-Abg-1236 | Absidia glauca | 40.74 | 4e-35 | 130 |
| LLPS-Kop-0067 | Komagataella pastoris | 40.58 | 2e-27 | 111 |
| LLPS-Sot-1859 | Solanum tuberosum | 40.56 | 4e-27 | 110 |
| LLPS-Zyt-1544 | Zymoseptoria tritici | 40.43 | 7e-26 | 105 |
| LLPS-Brr-0962 | Brassica rapa | 40.41 | 1e-25 | 106 |
| LLPS-Mel-1011 | Melampsora laricipopulina | 40.13 | 7e-30 | 116 |
| LLPS-Prp-2061 | Prunus persica | 39.86 | 2e-25 | 105 |
| LLPS-Miv-0878 | Microbotryum violaceum | 39.86 | 1e-24 | 102 |
| LLPS-Sac-1609 | Saccharomyces cerevisiae | 39.71 | 7e-27 | 108 |
| LLPS-Asc-0520 | Aspergillus clavatus | 39.6 | 1e-24 | 102 |
| LLPS-Phv-0955 | Phaseolus vulgaris | 39.58 | 7e-28 | 113 |
| LLPS-Ast-1407 | Aspergillus terreus | 39.19 | 6e-27 | 108 |
| LLPS-Dos-0373 | Dothistroma septosporum | 39.01 | 2e-26 | 107 |
| LLPS-Yal-1387 | Yarrowia lipolytica | 39.01 | 5e-27 | 109 |
| LLPS-Amt-1003 | Amborella trichopoda | 38.89 | 2e-23 | 99.8 |
| LLPS-Phn-1521 | Phaeosphaeria nodorum | 38.81 | 4e-23 | 98.2 |
| LLPS-Asni-0762 | Aspergillus niger | 38.78 | 5e-24 | 100 |
| LLPS-Asg-0675 | Ashbya gossypii | 38.69 | 2e-23 | 98.6 |
| LLPS-Nia-1676 | Nicotiana attenuata | 38.62 | 6e-25 | 104 |
| LLPS-Put-0269 | Puccinia triticina | 37.93 | 1e-24 | 102 |
| LLPS-Pug-1263 | Puccinia graminis | 37.66 | 8e-26 | 105 |
| LLPS-Asf-1445 | Aspergillus flavus | 37.16 | 2e-24 | 101 |
| LLPS-Aso-0672 | Aspergillus oryzae | 37.16 | 2e-24 | 101 |
| LLPS-Crn-1472 | Cryptococcus neoformans | 34.51 | 8e-16 | 77.4 |
| LLPS-Cym-0790 | Cyanidioschyzon merolae | 32.95 | 9e-22 | 95.5 |