LLPS-Cas-1194
FXR2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | fragile X mental retardation syndrome-related protein 2 |
| Gene Name: | FXR2 |
| Ensembl Gene: | ENSTSYG00000004564.2 |
| Ensembl Protein: | ENSTSYP00000004185.2 |
| Organism: | Carlito syrichta |
| Taxa ID: | 1868482 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTSYT00000004563.2 | ENSTSYP00000004185.2 |
| Ensembl | ENSTSYT00000029285.1 | ENSTSYP00000017489.1 |
| UniProt | A0A1U7U3Q6, A0A1U7U3Q6_TARSY | |
| RefSeq | , XM_008062340.1 | , XP_008060531.1, XP_008060531.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGGLASGGDV EPGLPVEVRG SNGAFYKGFV KDVHEDSVTI FFENNWQSER QIPFGDVRLP 60 61 PPADYNKEIT EGDEVEVYSR ANEQEPCGWW LARVRMMKGD FYVIEYAACD ATYNEIVTLE 120 121 RLRPVNPNPL ATKGSFFKVT MAVPEDLREA CSNENVHKEF KKALGTNCIF LNFTNSELFI 180 181 LSTTEAPVKR ASLLGDMHFR SLRTKLLLMS RNEEATKHLE TSKQLAAAFQ EEFTVREDLM 240 241 GLAIGTHGAN IQQARKVPGV TAIELGEETC TFRIYGETPE ACRQARSYLE FSEDSVQVPR 300 301 NLVGKVIGKN GKVIQEIVDK SGVVRVRVEG DNDKKNPREE GMVPFIFVGT RENISNAQAL 360 361 LEYHLSYLQE VEQLRLERLQ IDEQLRQIGL GFRPPGSGRG SGGSDKAGYA TDDSSSSLHA 420 421 TRTYGGSYGG RGRGRRTGGP AYGPSSDPST ASETESEKRE EPSRAGPGDR DPPTRGEESR 480 481 RRPIGGRGRG PPPAPRPTSR YNSSSISSVL KDPDSNPYSL LDTSEPEPPV DSEPGEPPPA 540 541 SARRRRSRRR RTDEDRTVMD GGLESDGPNM TENGLEDESR PQRRNRSRRR RNRGNRTDGS 600 601 ISGDRQPVTV ADYISRAESQ SRQRPPALER TKPSEDSLSG QKGDSVSKLS KGPSENGELS 660 661 APLELGSLVN GVS 673 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGGCGGCC TGGCCTCTGG GGGGGATGTG GAGCCGGGAC TGCCCGTCGA GGTGCGCGGC 60 61 TCCAACGGGG CCTTCTACAA GGGCTTTGTG AAGGATGTCC ATGAAGACTC TGTCACCATC 120 121 TTCTTTGAAA ACAACTGGCA AAGTGAAAGA CAGATTCCTT TTGGAGATGT CCGGCTACCA 180 181 CCTCCAGCTG ATTATAATAA GGAGATCACA GAAGGGGATG AGGTAGAGGT CTATTCTCGA 240 241 GCCAATGAAC AGGAACCTTG TGGCTGGTGG CTGGCACGGG TGCGGATGAT GAAGGGAGAT 300 301 TTCTATGTTA TTGAATATGC TGCTTGTGAT GCCACCTACA ATGAGATTGT CACCCTGGAG 360 361 CGACTTCGGC CAGTTAATCC CAATCCCCTT GCAACCAAAG GCAGCTTCTT CAAGGTTACC 420 421 ATGGCTGTGC CCGAGGATCT GAGAGAGGCC TGCTCCAATG AAAATGTCCA TAAAGAGTTC 480 481 AAGAAAGCAC TGGGAACCAA TTGCATCTTT CTCAACTTCA CAAATAGTGA ACTCTTTATT 540 541 CTGTCAACCA CAGAAGCCCC TGTGAAGCGG GCATCTCTGC TGGGTGATAT GCATTTCCGA 600 601 AGCCTACGTA CCAAACTGCT ACTCATGTCC CGCAATGAGG AAGCTACCAA GCACCTAGAG 660 661 ACAAGCAAGC AGTTGGCGGC AGCATTCCAG GAGGAGTTCA CAGTGCGTGA AGACCTAATG 720 721 GGACTGGCAA TTGGGACTCA TGGTGCCAAC ATCCAGCAGG CCCGAAAAGT ACCTGGGGTG 780 781 ACTGCCATTG AGTTGGGTGA AGAGACCTGC ACTTTCCGCA TCTATGGGGA GACCCCTGAG 840 841 GCCTGCCGAC AGGCCCGAAG CTACCTTGAG TTTTCTGAGG ATTCAGTGCA GGTGCCCAGG 900 901 AACCTGGTTG GCAAAGTGAT TGGGAAGAAT GGGAAAGTGA TCCAGGAGAT TGTGGATAAA 960 961 TCTGGTGTGG TGAGGGTTCG AGTGGAAGGT GATAATGACA AGAAGAACCC CAGGGAGGAG 1020 1021 GGAATGGTTC CTTTCATATT TGTTGGCACC CGAGAGAATA TCAGCAATGC CCAGGCTCTG 1080 1081 TTGGAATATC ATCTCTCCTA CCTGCAGGAG GTGGAGCAGC TTCGCTTGGA GAGGCTGCAA 1140 1141 ATTGATGAAC AGCTTCGGCA GATTGGGCTG GGCTTTCGCC CTCCTGGGAG TGGGCGGGGC 1200 1201 AGCGGTGGCA GCGACAAGGC TGGATATGCC ACTGATGACT CCTCTTCCTC CCTCCATTTT 1260 1261 GGGGGCTGTA ATGGATCCTG GGATGGAATG GGTGGTCCCA GCTCTGACCC ATCCACAGCT 1320 1321 TCTGAGACCG AGTCAGAGAA GAGAGAGGAG CCCAGCCGAG CTGGACCTGG TGACAGGGAT 1380 1381 CCCCCAACCC GAGGGGAAGA AAGCCGGAGG CGGCCGATTG GGGGCCGGGG TAGGGGACCC 1440 1441 CCACCTGCCC CCCGGCCCAC CTCCAGATAT AATTCTTCAT CTATTAGCTC AGTGCTGAAG 1500 1501 GATCCAGACA GTAATCCCTA TAGCCTATTG GACACATCTG AACCAGAGCC CCCAGTTGAT 1560 1561 TCAGAGCCTG GAGAACCTCC CCCAGCAAGT GCCAGGCGCC GCCGCTCCCG TCGCCGTCGC 1620 1621 ACTGATGAAG ACAGGACTGT CATGGATGGA GGCCTGGAAT CAGATGGGCC CAACATGACA 1680 1681 GAGAATGGCC TGGAAGATGA ATCAAGACCC CAACGTCGTA ATCGCAGCCG CCGCCGCCGT 1740 1741 AACCGTGGTA ACCGGACTGA CGGTTCTATC AGTGGAGACC GCCAGCCAGT GACTGTGGCT 1800 1801 GACTATATCT CACGAGCAGA GTCTCAAAGT CGCCAGCGGC CACCAGCCCT GGAACGCACT 1860 1861 AAACCCTCAG AGGACTCTCT TTCAGGACAG AAGGGTGACT CTGTCAGCAA GCTTTCTAAG 1920 1921 GGCCCCTCGG AGAATGGGGA GCTCTCCGCA CCCCTGGAGT TGGGTAGTTT GGTGAATGGG 1980 1981 GTTTCATAA 1989 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Paa-0751 | Papio anubis | 98.52 | 0.0 | 1049 |
| LLPS-Chs-0587 | Chlorocebus sabaeus | 98.52 | 0.0 | 1049 |
| LLPS-Maf-0731 | Macaca fascicularis | 98.52 | 0.0 | 1049 |
| LLPS-Cea-1461 | Cercocebus atys | 98.52 | 0.0 | 1049 |
| LLPS-Mam-1067 | Macaca mulatta | 98.52 | 0.0 | 1049 |
| LLPS-Man-2180 | Macaca nemestrina | 98.52 | 0.0 | 1049 |
| LLPS-Gog-1909 | Gorilla gorilla | 98.37 | 0.0 | 1047 |
| LLPS-Pat-4100 | Pan troglodytes | 98.37 | 0.0 | 1048 |
| LLPS-Hos-2553 | Homo sapiens | 98.37 | 0.0 | 1047 |
| LLPS-Rhb-3826 | Rhinopithecus bieti | 98.37 | 0.0 | 1049 |
| LLPS-Aon-2862 | Aotus nancymaae | 98.22 | 0.0 | 1047 |
| LLPS-Caj-0607 | Callithrix jacchus | 98.07 | 0.0 | 1047 |
| LLPS-Fec-3142 | Felis catus | 98.07 | 0.0 | 1063 |
| LLPS-Sus-2477 | Sus scrofa | 98.05 | 0.0 | 1039 |
| LLPS-Bot-3091 | Bos taurus | 97.92 | 0.0 | 1049 |
| LLPS-Eqc-1256 | Equus caballus | 97.92 | 0.0 | 1038 |
| LLPS-Orc-2003 | Oryctolagus cuniculus | 97.84 | 0.0 | 992 |
| LLPS-Loa-3240 | Loxodonta africana | 97.68 | 0.0 | 998 |
| LLPS-Mea-2953 | Mesocricetus auratus | 97.48 | 0.0 | 1049 |
| LLPS-Otg-0143 | Otolemur garnettii | 97.33 | 0.0 | 1034 |
| LLPS-Urm-0997 | Ursus maritimus | 97.16 | 0.0 | 974 |
| LLPS-Caf-0533 | Canis familiaris | 96.59 | 0.0 | 1058 |
| LLPS-Ict-2020 | Ictidomys tridecemlineatus | 96.59 | 0.0 | 1051 |
| LLPS-Mum-4367 | Mus musculus | 96.3 | 0.0 | 1045 |
| LLPS-Ran-2098 | Rattus norvegicus | 96.15 | 0.0 | 1045 |
| LLPS-Tut-1062 | Tursiops truncatus | 95.83 | 0.0 | 1033 |
| LLPS-Dio-0478 | Dipodomys ordii | 95.83 | 0.0 | 984 |
| LLPS-Ora-1674 | Ornithorhynchus anatinus | 95.74 | 0.0 | 573 |
| LLPS-Ova-1199 | Ovis aries | 94.51 | 0.0 | 1042 |
| LLPS-Cap-1689 | Cavia porcellus | 94.51 | 0.0 | 1033 |
| LLPS-Fud-0756 | Fukomys damarensis | 94.48 | 0.0 | 1025 |
| LLPS-Pap-1149 | Pan paniscus | 94.16 | 0.0 | 958 |
| LLPS-Mal-0677 | Mandrillus leucophaeus | 94.03 | 0.0 | 957 |
| LLPS-Nol-2893 | Nomascus leucogenys | 93.77 | 0.0 | 1019 |
| LLPS-Myl-3670 | Myotis lucifugus | 93.18 | 0.0 | 1001 |
| LLPS-Poa-1494 | Pongo abelii | 92.26 | 0.0 | 938 |
| LLPS-Aim-2714 | Ailuropoda melanoleuca | 91.73 | 0.0 | 975 |
| LLPS-Mup-4038 | Mustela putorius furo | 91.05 | 0.0 | 1021 |
| LLPS-Sah-1642 | Sarcophilus harrisii | 90.21 | 0.0 | 981 |
| LLPS-Mod-3508 | Monodelphis domestica | 89.81 | 0.0 | 789 |
| LLPS-Pof-2986 | Poecilia formosa | 78.4 | 0.0 | 589 |
| LLPS-Xim-2256 | Xiphophorus maculatus | 78.13 | 0.0 | 587 |
| LLPS-Orl-1019 | Oryzias latipes | 76.53 | 0.0 | 582 |
| LLPS-Anc-0528 | Anolis carolinensis | 75.51 | 4e-08 | 60.5 |
| LLPS-Meg-1667 | Meleagris gallopavo | 75.51 | 6e-08 | 60.1 |
| LLPS-Gaa-1376 | Gasterosteus aculeatus | 74.67 | 0.0 | 559 |
| LLPS-Xet-0909 | Xenopus tropicalis | 73.6 | 0.0 | 569 |
| LLPS-Fia-0578 | Ficedula albicollis | 73.6 | 0.0 | 570 |
| LLPS-Gaga-2269 | Gallus gallus | 73.33 | 0.0 | 570 |
| LLPS-Lac-2134 | Latimeria chalumnae | 73.08 | 3e-08 | 60.8 |
| LLPS-Pes-1591 | Pelodiscus sinensis | 71.74 | 0.0 | 545 |
| LLPS-Scm-0980 | Scophthalmus maximus | 71.58 | 0.0 | 546 |
| LLPS-Anp-0142 | Anas platyrhynchos | 71.47 | 3e-165 | 495 |
| LLPS-Icp-1457 | Ictalurus punctatus | 71.28 | 0.0 | 548 |
| LLPS-Ten-0614 | Tetraodon nigroviridis | 67.25 | 0.0 | 634 |
| LLPS-Leo-1066 | Lepisosteus oculatus | 66.35 | 0.0 | 554 |
| LLPS-Orn-0455 | Oreochromis niloticus | 65.06 | 1e-180 | 535 |
| LLPS-Tag-2305 | Taeniopygia guttata | 64.94 | 6e-177 | 524 |
| LLPS-Scf-1903 | Scleropages formosus | 63.96 | 0.0 | 656 |
| LLPS-Dar-3686 | Danio rerio | 63.72 | 0.0 | 692 |
| LLPS-Asm-2103 | Astyanax mexicanus | 62.73 | 0.0 | 657 |
| LLPS-Ere-0650 | Erinaceus europaeus | 58.28 | 0.0 | 652 |
| LLPS-Tar-2104 | Takifugu rubripes | 57.86 | 0.0 | 643 |
| LLPS-Cii-2219 | Ciona intestinalis | 52.49 | 6e-122 | 378 |
| LLPS-Cis-0309 | Ciona savignyi | 51.68 | 4e-87 | 282 |
| LLPS-Drm-0206 | Drosophila melanogaster | 47.12 | 9e-113 | 362 |