LLPS-Cap-a1114
VPS16
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Vacuolar protein sorting-associated protein 16 homolog |
| Gene Name: | VPS16 |
| Ensembl Gene: | ENSCPOG00000003602.4 |
| Ensembl Protein: | ENSCPOP00000023345.1 |
| Organism: | Cavia porcellus |
| Taxa ID: | 10141 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCPOT00000045060.1 | ENSCPOP00000023345.1 |
| Ensembl | ENSCPOT00000003646.3 | ENSCPOP00000003253.2 |
| UniProt | H0V193, H0V193_CAVPO | |
| GeneBank | AAKN02012838 | |
| RefSeq | XM_003476625.3 | XP_003476673.1 |
| Entrez | 100721004 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDCYTANWNP LGDSAFYRKY ELYSMDWDLK EELRECLVAA APYGGPIALL RNPWRKEKAA 60 61 SVRPVLEIYS ASGVPLASLL WKSGPVMSMG WSAEEELLCV QEDGAVLVYG LHGDFRRHFS 120 121 MGNEVLQNRV LDARIFHTEL GSGVAILTGA YRFTLSANVG DLKLRRMPEV PGLQSAPSCW 180 181 TTLFQERVAH ILLAVGPDLY LLDHATCSAV TPPGLPSGVT SFLQMAVSFT YRHLALFTDT 240 241 GYIWMGTASL TEKLCEFNCN IRAPPKQMVW CSRPRSKERA VVVAWERRLM VVGNAPESIQ 300 301 FVLDEDSYLV PELDGVRIFS RSSHEFLHEV PVASEEIFKI ASMAPGALLL EAQKEYEKES 360 361 QKADEYLREI QELGQLTQAV QQCIEAAGHE HGPDMQKSLL RAASFGKCFL DRFPPDSFVR 420 421 MCQDLRVLNA VRDYHIGIPL TYSQYKQLTI QVLLDRLVLR RLYPLAIQIC EYLRLPEVQG 480 481 VSRILAHWAC YKVQQKDVSD EDVARAINQK LGDTPGVSYS DIAARAYGCG RTELAIKLLE 540 541 YEPRSGEQVP LLLKMKRSKL ALNKAIESGD TDLVFTVLLH LKNELNRGDF FMTLRNQPMA 600 601 LSLYRQFCKH QELETLKDLY NQDDNHQELG SFHLRASYAA EERIEGRVAA LQTAADAFYK 660 661 AKNEFAAKAT EDQMRLLRLQ RRLEDELGGQ FLDLSLHDTV TTLIVGGHNK RAEQLARDFR 720 721 IPDKRLWWLK LTALADLEDW EELEKFSKTK KSPIGYLPFV EICMKQHNKY EAKKYASRVG 780 781 PEQKVKALLL VGDVAQAADV AIEHRNEAEL SLVLSHCTGA SDGATADKIQ RARAQAQKK 839 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGATTGCT ACACAGCGAA CTGGAACCCG CTCGGAGATT CTGCCTTTTA CCGGAAATAT 60 61 GAACTGTACA GCATGGACTG GGACCTGAAG GAGGAACTCA GAGAATGCTT GGTGGCTGCT 120 121 GCACCCTACG GGGGCCCCAT TGCACTGCTA AGGAACCCCT GGCGAAAGGA GAAAGCTGCC 180 181 AGCGTGCGGC CAGTGCTTGA GATCTATTCA GCTTCTGGTG TGCCCCTGGC CAGCCTGCTG 240 241 TGGAAGAGTG GTCCTGTGAT GTCCATGGGC TGGTCTGCTG AGGAAGAACT GCTCTGTGTG 300 301 CAGGAAGATG GTGCAGTACT GGTTTATGGG CTTCATGGTG ACTTCCGGAG GCACTTTAGC 360 361 ATGGGCAATG AAGTGCTGCA GAACCGGGTT CTAGATGCCC GGATCTTTCA CACTGAGCTT 420 421 GGTTCTGGAG TGGCCATCCT CACAGGGGCC TATCGCTTTA CCCTTAGTGC CAATGTGGGC 480 481 GACCTCAAAC TCCGCCGGAT GCCAGAGGTG CCAGGCCTGC AAAGTGCACC CTCATGTTGG 540 541 ACCACATTGT TCCAGGAACG AGTGGCACAC ATTCTTCTGG CTGTGGGGCC CGATCTCTAT 600 601 CTCCTGGATC ACGCAACCTG TTCTGCAGTG ACACCCCCTG GCCTACCCTC AGGAGTGACC 660 661 AGCTTCCTGC AGATGGCTGT CTCCTTTACC TATCGACACC TAGCACTCTT CACAGACACA 720 721 GGCTACATCT GGATGGGGAC AGCATCACTT ACAGAGAAGC TGTGTGAGTT CAACTGCAAC 780 781 ATCCGGGCAC CCCCAAAGCA AATGGTCTGG TGCAGTCGCC CTCGAAGCAA GGAGAGGGCT 840 841 GTCGTGGTGG CCTGGGAGAG GCGGCTAATG GTGGTGGGCA ATGCACCTGA GAGCATCCAA 900 901 TTTGTGCTAG ATGAGGACTC TTACCTGGTT CCTGAGCTCG ATGGAGTCCG TATCTTCTCC 960 961 CGCAGCAGTC ACGAGTTTCT GCATGAGGTT CCAGTGGCCA GTGAGGAGAT CTTCAAAATT 1020 1021 GCTTCAATGG CCCCTGGAGC ACTGCTGTTG GAAGCCCAGA AAGAATATGA GAAAGAGAGC 1080 1081 CAGAAGGCAG ATGAGTACCT GCGAGAGATT CAGGAGCTGG GCCAGCTGAC CCAGGCTGTG 1140 1141 CAGCAGTGCA TTGAAGCCGC AGGACATGAG CATGGGCCAG ACATGCAGAA GAGTCTGCTC 1200 1201 AGGGCGGCCT CCTTTGGAAA GTGTTTCCTC GACAGATTTC CACCTGACAG CTTTGTACGC 1260 1261 ATGTGTCAGG ACCTGCGTGT GCTCAATGCT GTTCGGGACT ACCACATTGG GATCCCCCTC 1320 1321 ACCTACAGCC AATATAAGCA ACTTACCATC CAGGTGTTAC TAGACAGGCT CGTGTTACGG 1380 1381 AGACTTTACC CCCTTGCCAT CCAGATATGC GAGTACTTGC GCCTTCCAGA AGTACAGGGT 1440 1441 GTCAGCAGGA TCCTGGCTCA CTGGGCCTGC TATAAGGTAC AACAGAAGGA TGTGTCAGAT 1500 1501 GAGGATGTTG CACGAGCCAT TAATCAGAAA CTGGGAGACA CTCCTGGTGT CTCATATTCA 1560 1561 GACATTGCTG CACGGGCCTA TGGCTGTGGC CGCACAGAGC TGGCCATCAA GCTCCTGGAG 1620 1621 TATGAACCAC GTTCAGGGGA GCAAGTACCC CTCCTCCTCA AGATGAAAAG GAGCAAACTG 1680 1681 GCACTAAACA AGGCCATTGA GAGTGGGGAC ACAGACCTGG TGTTCACGGT GTTGCTGCAC 1740 1741 CTGAAGAATG AGCTGAACCG AGGAGACTTT TTCATGACCC TCCGGAACCA GCCCATGGCC 1800 1801 CTGAGTTTGT ACCGACAGTT TTGTAAGCAT CAGGAGCTAG AGACACTGAA GGACCTCTAC 1860 1861 AATCAAGATG ACAATCACCA GGAATTGGGC AGCTTCCACC TCCGAGCCAG CTATGCTGCA 1920 1921 GAAGAGCGCA TTGAGGGGCG AGTTGCAGCT CTGCAGACAG CAGCTGATGC CTTTTACAAG 1980 1981 GCCAAGAATG AGTTTGCAGC CAAGGCCACA GAGGATCAAA TGCGCCTCCT TCGGCTACAA 2040 2041 CGGCGCCTAG AAGATGAGCT GGGAGGCCAG TTCCTAGACC TGTCTCTACA TGACACAGTC 2100 2101 ACGACCCTCA TTGTTGGTGG TCACAACAAG CGTGCAGAGC AGCTGGCACG TGACTTCCGC 2160 2161 ATCCCTGACA AGAGGCTCTG GTGGCTGAAG CTCACTGCCC TGGCAGATTT GGAAGACTGG 2220 2221 GAGGAGCTGG AGAAGTTTTC CAAGACCAAA AAATCACCGA TTGGTTACCT GCCCTTCGTG 2280 2281 GAAATCTGCA TGAAGCAGCA CAACAAATAT GAAGCCAAGA AATATGCATC CCGAGTGGGT 2340 2341 CCTGAGCAGA AGGTCAAGGC CTTGCTTCTT GTTGGAGACG TGGCCCAGGC TGCAGATGTG 2400 2401 GCCATTGAAC ACCGGAATGA GGCTGAGTTG AGCCTTGTGT TGTCCCACTG CACTGGAGCC 2460 2461 TCTGATGGAG CCACAGCTGA CAAGATTCAA CGGGCCAGAG CACAAGCCCA GAAGAAG 2517 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | CORVET complex | |
Cellular Component | Early endosome | |
Cellular Component | HOPS complex | |
Cellular Component | Late endosome membrane | |
Cellular Component | Lysosomal membrane | |
Cellular Component | Recycling endosome | |
Biological Process | Autophagosome maturation | |
Biological Process | Endosome to lysosome transport | |
Biological Process | Intracellular protein transport | |
Biological Process | Vacuole organization |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a1150 | Homo sapiens | 0.0 | 1691 | undefined |
| LLPS-Mum-a1130 | Mus musculus | 0.0 | 1625 | undefined |