• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cap-1028
DYRK1A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: DYRK1A
Ensembl Gene: ENSCPOG00000037211.1
Ensembl Protein: ENSCPOP00000022097.1
Organism: Cavia porcellus
Taxa ID: 10141
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Nuclear specklePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MHTGGETSAC  KPSSVRLAPS  FSFHAAGLQM  AGQMPHSHQY  SDRRQPNISD  QQVSALPYSD  60
61    QIQQPLTNQV  MPDIVMLQRR  MPQTFRDPST  APLRKLSVDL  IKTYKHINEV  YYAKKKRRHQ  120
121   QGQGDDSSHK  KERKVYNDGY  DDDNYDYIVK  NGEKWMDRYE  IDSLIGKGSF  GQVVKAYDRV  180
181   EQEWVAIKII  KNKKAFLNQA  QIEVRLLELM  NKHDTEMKYY  IVHLKRHFMF  RNHLCLVFEM  240
241   LSYNLYDLLR  NTNFRGVSLN  LTRKFAQQMC  TALLFLATPE  LSIIHCDLKP  ENILLCNPKR  300
301   SAIKIVDFGS  SCQLGQRIYQ  YIQSRFYRSP  EVLLGMPYDL  AIDMWSLGCI  LVEMHTGEPL  360
361   FSGANEVDQM  NKIVEVLGIP  PAHILDQAPK  ARKFFEKLPD  GTWNLKKTKD  GKREYKPPGS  420
421   RKLHNILGVE  TGGPGGRRAG  ESGHTVADYL  KFKDLILRML  DYDPKSRIQP  YYALQHSFFK  480
481   KTADEGTNTS  NSVSTSPAME  QSQSSGTTSS  TSSSSGGSSG  TSNSGRARSD  PTHQHRHSGG  540
541   HFTAAVQAMD  CETHSPQVRQ  QFPAPLGWSG  TEAPTQVTVE  NHPVQETTFH  VAPQQNALHH  600
601   HHGNSSHHHH  HHHHHHHHHG  QQALGNRTRP  RVYNSPTNSS  STQDSMEVGH  SHHSMTSLSS  660
661   STTSSSTSSS  STGNQGNQAY  QNRPVAANTL  DFGQNGAMDV  NLTVYSNPRQ  ETGIAGHPTY  720
721   QFSANTGPAH  YMTEGHLTMR  QGTDREESPM  TGVCVQQSPV  ASS  763
Nucleotide CDS Sequence (FASTA)
1     ATGCATACAG  GAGGAGAGAC  TTCAGCATGC  AAACCTTCAT  CTGTTCGGCT  TGCACCGTCA  60
61    TTTTCATTCC  ATGCTGCTGG  CCTTCAGATG  GCTGGACAGA  TGCCCCATTC  ACATCAGTAC  120
121   AGTGACCGTC  GCCAGCCAAA  CATAAGTGAC  CAACAGGTTT  CTGCCTTACC  GTATTCTGAC  180
181   CAGATTCAGC  AACCTCTAAC  TAACCAGGTG  ATGCCTGATA  TTGTCATGTT  ACAGAGGCGG  240
241   ATGCCCCAAA  CCTTCCGTGA  TCCATCAACT  GCTCCTCTGA  GAAAACTTTC  TGTTGATTTG  300
301   ATCAAAACAT  ATAAGCATAT  TAATGAGGTT  TACTATGCAA  AAAAGAAGCG  AAGACACCAG  360
361   CAGGGCCAGG  GAGACGATTC  AAGTCATAAG  AAGGAGCGGA  AGGTTTACAA  TGATGGTTAC  420
421   GATGACGACA  ACTATGATTA  TATTGTAAAG  AACGGGGAAA  AGTGGATGGA  TCGTTACGAA  480
481   ATTGACTCCT  TGATAGGCAA  AGGTTCCTTT  GGACAGGTTG  TGAAAGCATA  TGATCGGGTG  540
541   GAGCAAGAAT  GGGTTGCCAT  TAAAATCATA  AAAAATAAGA  AGGCGTTTCT  GAATCAAGCC  600
601   CAGATAGAAG  TGCGACTTCT  TGAGCTCATG  AACAAACATG  ACACGGAAAT  GAAATACTAC  660
661   ATAGTGCATT  TGAAACGCCA  CTTTATGTTT  CGAAACCATC  TCTGTTTGGT  GTTTGAAATG  720
721   CTGTCCTACA  ACCTCTATGA  CCTGTTGAGG  AACACCAATT  TCCGGGGGGT  CTCTTTGAAC  780
781   CTGACAAGGA  AGTTCGCGCA  GCAGATGTGC  ACTGCACTGC  TTTTCCTGGC  GACTCCAGAG  840
841   TTGAGTATTA  TTCACTGTGA  CCTGAAACCT  GAGAACATCC  TCCTCTGCAA  CCCCAAACGA  900
901   AGCGCCATCA  AGATCGTTGA  CTTCGGCAGT  TCTTGTCAGC  TGGGGCAGAG  GATATACCAG  960
961   TATATCCAGA  GTCGCTTTTA  TCGGTCTCCA  GAGGTGCTAT  TGGGAATGCC  TTATGATCTT  1020
1021  GCTATCGACA  TGTGGTCCCT  TGGGTGTATT  TTGGTTGAAA  TGCACACTGG  AGAACCTCTG  1080
1081  TTTAGTGGTG  CCAATGAGGT  AGATCAGATG  AATAAAATAG  TGGAAGTTCT  GGGTATTCCA  1140
1141  CCTGCTCATA  TTCTTGACCA  AGCACCAAAA  GCAAGAAAGT  TCTTTGAGAA  GCTGCCAGAT  1200
1201  GGCACTTGGA  ACTTAAAGAA  GACCAAAGAT  GGAAAACGGG  AGTACAAACC  ACCAGGAAGC  1260
1261  CGTAAACTTC  ATAATATTCT  TGGAGTAGAA  ACAGGAGGGC  CTGGTGGCCG  GCGTGCTGGG  1320
1321  GAGTCGGGTC  ACACCGTAGC  TGACTACTTG  AAGTTCAAAG  ACCTCATCTT  AAGGATGCTG  1380
1381  GATTATGATC  CCAAATCTCG  AATTCAACCT  TACTATGCCC  TGCAGCACAG  TTTTTTCAAG  1440
1441  AAAACAGCCG  ATGAAGGTAC  AAATACGAGT  AACAGCGTCT  CCACAAGCCC  TGCGATGGAG  1500
1501  CAGTCCCAGT  CTTCAGGCAC  CACCTCCAGC  ACGTCATCCA  GCTCAGGTGG  ATCATCCGGG  1560
1561  ACAAGCAACA  GTGGGAGAGC  CAGGTCGGAC  CCCACGCACC  AGCATCGGCA  CAGCGGCGGG  1620
1621  CACTTCACGG  CCGCGGTCCA  GGCCATGGAC  TGCGAGACGC  ACAGTCCCCA  GGTGCGTCAG  1680
1681  CAGTTTCCAG  CACCACTCGG  CTGGTCAGGC  ACTGAAGCTC  CTACACAGGT  CACTGTTGAA  1740
1741  AATCATCCCG  TTCAAGAAAC  AACCTTTCAC  GTAGCCCCTC  AGCAGAATGC  GTTGCATCAT  1800
1801  CACCATGGAA  ACAGTTCCCA  TCACCACCAC  CACCACCACC  ACCACCACCA  CCACCATGGA  1860
1861  CAGCAAGCCT  TGGGTAACCG  GACCAGGCCA  AGGGTCTACA  ATTCTCCAAC  AAATAGCTCC  1920
1921  TCTACCCAGG  ATTCTATGGA  GGTTGGCCAC  AGTCACCACT  CCATGACATC  TCTGTCTTCC  1980
1981  TCAACGACTT  CTTCCTCGAC  ATCTTCCTCC  TCTACTGGTA  ATCAAGGCAA  TCAGGCCTAC  2040
2041  CAGAACCGCC  CGGTGGCTGC  TAATACCTTG  GACTTTGGAC  AGAATGGAGC  TATGGACGTC  2100
2101  AATTTGACCG  TCTACTCCAA  TCCCCGCCAA  GAGACTGGCA  TAGCTGGACA  CCCAACATAC  2160
2161  CAGTTTTCTG  CTAACACAGG  CCCTGCACAT  TACATGACTG  AAGGACACCT  GACAATGAGG  2220
2221  CAAGGGACTG  ACAGAGAAGA  GTCCCCCATG  ACAGGAGTTT  GTGTGCAGCA  GAGTCCTGTA  2280
2281  GCTAGCTCGT  GA  2292

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tut-1032Tursiops truncatus99.280.01039
LLPS-Gog-2494Gorilla gorilla99.240.0 889
LLPS-Pat-3473Pan troglodytes99.210.01357
LLPS-Pap-3529Pan paniscus99.210.01347
LLPS-Hos-1205Homo sapiens99.210.01357
LLPS-Loa-1305Loxodonta africana99.210.01348
LLPS-Otg-3007Otolemur garnettii99.210.01356
LLPS-Poa-0309Pongo abelii99.10.0 728
LLPS-Bot-2412Bos taurus99.080.01355
LLPS-Dio-2540Dipodomys ordii99.080.01347
LLPS-Aon-0494Aotus nancymaae99.080.01351
LLPS-Paa-3608Papio anubis98.950.01353
LLPS-Cea-2691Cercocebus atys98.950.01353
LLPS-Fud-0761Fukomys damarensis98.950.01353
LLPS-Cas-3871Carlito syrichta98.950.01354
LLPS-Man-1387Macaca nemestrina98.950.01353
LLPS-Rhb-2691Rhinopithecus bieti98.950.01353
LLPS-Ran-1815Rattus norvegicus98.820.01352
LLPS-Myl-2830Myotis lucifugus98.820.01342
LLPS-Mea-1692Mesocricetus auratus98.690.01349
LLPS-Mum-2701Mus musculus98.690.01351
LLPS-Orc-1489Oryctolagus cuniculus98.690.01344
LLPS-Aim-2572Ailuropoda melanoleuca98.550.01341
LLPS-Nol-1237Nomascus leucogenys98.30.01337
LLPS-Sus-4545Sus scrofa98.040.01346
LLPS-Caj-3245Callithrix jacchus98.030.01330
LLPS-Eqc-0294Equus caballus98.030.01331
LLPS-Ict-1723Ictidomys tridecemlineatus97.90.01329
LLPS-Mal-2738Mandrillus leucophaeus97.770.01326
LLPS-Maf-0547Macaca fascicularis97.770.01326
LLPS-Mam-1958Macaca mulatta97.770.01326
LLPS-Chs-2796Chlorocebus sabaeus97.680.01266
LLPS-Urm-2680Ursus maritimus97.640.01324
LLPS-Mup-2386Mustela putorius furo97.510.01323
LLPS-Caf-0323Canis familiaris97.240.01309
LLPS-Ova-1692Ovis aries97.120.01328
LLPS-Fec-2740Felis catus97.120.01317
LLPS-Ora-0632Ornithorhynchus anatinus96.990.01315
LLPS-Sah-2509Sarcophilus harrisii96.730.01306
LLPS-Ten-1420Tetraodon nigroviridis96.634e-135 405
LLPS-Mod-0629Monodelphis domestica96.60.01301
LLPS-Gaga-3630Gallus gallus96.080.01298
LLPS-Meg-1660Meleagris gallopavo95.930.01289
LLPS-Tag-0956Taeniopygia guttata95.540.01283
LLPS-Anc-0468Anolis carolinensis95.030.01285
LLPS-Pes-1883Pelodiscus sinensis94.770.01268
LLPS-Fia-3019Ficedula albicollis94.270.01284
LLPS-Lac-1519Latimeria chalumnae93.990.01286
LLPS-Anp-0518Anas platyrhynchos92.550.01265
LLPS-Leo-3715Lepisosteus oculatus90.050.01232
LLPS-Icp-3569Ictalurus punctatus87.960.0 732
LLPS-Dar-3363Danio rerio87.760.0 733
LLPS-Scf-0831Scleropages formosus85.280.01105
LLPS-Orn-0624Oreochromis niloticus82.410.01092
LLPS-Drm-1474Drosophila melanogaster82.340.0 662
LLPS-Orl-2928Oryzias latipes81.830.01079
LLPS-Gaa-0601Gasterosteus aculeatus81.630.01080
LLPS-Tar-3086Takifugu rubripes81.570.01077
LLPS-Asm-1662Astyanax mexicanus81.570.01068
LLPS-Scm-0042Scophthalmus maximus81.440.01073
LLPS-Xim-2729Xiphophorus maculatus81.390.01025
LLPS-Pof-2737Poecilia formosa80.420.01056
LLPS-Cii-0267Ciona intestinalis79.520.0 631
LLPS-Xet-3463Xenopus tropicalis78.850.01095
LLPS-Cae-0669Caenorhabditis elegans70.034e-150 468
LLPS-Cis-1522Ciona savignyi45.712e-86 286
LLPS-Nef-0376Neosartorya fischeri45.242e-81 285
LLPS-Asc-0705Aspergillus clavatus44.972e-81 285
LLPS-Blg-0683Blumeria graminis44.617e-81 281
LLPS-Put-0441Puccinia triticina44.581e-83 296
LLPS-Ast-0116Aspergillus terreus44.311e-80 282
LLPS-Crn-0948Cryptococcus neoformans44.282e-86 305
LLPS-Chr-1349Chlamydomonas reinhardtii44.011e-86 303
LLPS-Nec-0524Neurospora crassa43.92e-82 292
LLPS-Miv-1213Microbotryum violaceum43.791e-82 295
LLPS-Ere-0389Erinaceus europaeus43.622e-81 276
LLPS-Phn-0409Phaeosphaeria nodorum43.61e-81 290
LLPS-Asni-0586Aspergillus niger43.292e-81 290
LLPS-Mao-0939Magnaporthe oryzae42.997e-81 287
LLPS-Asfu-1169Aspergillus fumigatus42.992e-81 288
LLPS-Spr-0318Sporisorium reilianum42.93e-83 297
LLPS-Usm-1120Ustilago maydis42.868e-83 295
LLPS-Aso-1071Aspergillus oryzae42.689e-83 280
LLPS-Asf-0556Aspergillus flavus42.682e-82 291
LLPS-Coo-0223Colletotrichum orbiculare42.688e-81 286
LLPS-Cog-0036Colletotrichum gloeosporioides42.688e-81 287
LLPS-Tum-1414Tuber melanosporum42.423e-82 292
LLPS-Abg-1599Absidia glauca42.331e-81 288
LLPS-Trr-0672Trichoderma reesei40.45e-81 271
LLPS-Pytr-0816Pyrenophora triticirepentis40.179e-81 275