LLPS-Caj-a238
TIMM50
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitochondrial import inner membrane translocase subunit TIM50 |
| Gene Name: | TIMM50 |
| Ensembl Gene: | ENSCJAG00000014276.3 |
| Ensembl Protein: | ENSCJAP00000052632.1 |
| Organism: | Callithrix jacchus |
| Taxa ID: | 9483 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCJAT00000068083.1 | ENSCJAP00000052632.1 |
| Ensembl | ENSCJAT00000079882.1 | ENSCJAP00000055953.1 |
| Ensembl | ENSCJAT00000027736.3 | ENSCJAP00000026247.3 |
| UniProt | F7ITE1, F7ITE1_CALJA | |
| Entrez | 100397616 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MASALPLGNL TTSLAASFAS AVALRTAQVG RGPDDFGSQL VPPGTSNRIV GANVPAAIRP 60 61 KPLVYFGLPE QVGGAAWRQR KMATSVALLS RLRSGLRLGL RGLCTRLATP PPRAPDQVAE 120 121 IGSRGGTQAQ GPQQQPGSEG PSYAKKVALW LAGLLGAGGT VSVVYIFGNN SVDEKDPILV 180 181 QQLRRTYKYF KDYRQMIIEP TSPCLLPDPL QEPYYQPPYT LVLELTGVLL HPEWSLATGW 240 241 RFKKRPGIET LFQQLAPLYE IVIFTSETGM TAFPLIDSVD PHGFISYRLF RDATRYMDGH 300 301 HVKDISCLNR DPARVVVVDC KKEAFRLQPY NGVALRPWDG NSDDRVLLDL SAFLKTIALN 360 361 GVEDVRTVLE HYALEDDPLA AFKQRQSRLE QEEQQRLAEL SKSNKQNLFF SSLTSRLWPR 420 421 SKQP 424 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGACCT CGGTAGCTCT GTTATCGCGC TTGCGGAGCG GGCTCCGGCT AGGCTTGCGG 60 61 GGACTGTGCA CGAGGTTGGC GACGCCGCCC CCCCGGGCTC CGGATCAGGT CGCTGAGATC 120 121 GGGAGCCGCG GGGGCACTCA GGCACAGGGG CCACAGCAGC AGCCGGGCTC AGAGGGTCCC 180 181 AGCTATGCCA AAAAAGTTGC TCTCTGGCTT GCTGGACTGC TTGGAGCTGG TGGGACCGTG 240 241 AGCGTCGTCT ATATCTTTGG AAACAACTCT GTGGACGAAA AAGGTGCCAA GATTCCTGAT 300 301 GAATTCGACA ATGATCCAAT TCTGGTACAG CAGTTGCGCC GGACATACAA ATATTTCAAA 360 361 GATTACAGAC AGATGATCAT CGAGCCCACC AGCCCTTGCC TTCTCCCAGA CCCTCTGCAG 420 421 GAGCCGTACT ACCAGCCGCC CTATACGCTC GTTTTGGAGC TCACCGGTGT CCTCTTGCAT 480 481 CCTGAGTGGT CGCTGGCCAC TGGCTGGAGG TTTAAGAAGC GCCCAGGCAT CGAGACCCTG 540 541 TTCCAGCAGC TTGCCCCTTT ATATGAAATT GTCATCTTTA CGTCGGAGAC TGGCATGACT 600 601 GCCTTTCCAC TCATTGACAG TGTGGACCCC CACGGCTTCA TCTCCTACCG CCTATTCCGG 660 661 GACGCCACGA GATACATGGA TGGGCACCAT GTTAAGGACA TTTCATGTCT GAATCGGGAC 720 721 CCAGCTCGAG TAGTAGTTGT GGACTGTAAG AAGGAAGCCT TCCGCCTGCA GCCCTATAAC 780 781 GGCGTCGCCC TGCGGCCCTG GGATGGCAAC TCTGATGACC GGGTCTTGTT GGACCTGTCA 840 841 GCCTTTCTCA AGACCATTGC ACTGAACGGT GTGGAGGACG TGCGGACTGT ACTGGAGCAC 900 901 TATGCCCTGG AGGATGACCC ACTGGCGGCT TTCAAACAGC GGCAAAGCCG GCTAGAGCAG 960 961 GAGGAGCAGC AGCGCCTGGC CGAGCTCTCC AAGTCCAACA AGCAGAACCT CTTCTTCAGC 1020 1021 TCCCTCACCA GCCGCTTGTG GCCTCGCTCC AAACAGCCCT GA 1062 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Nuclear speck | |
Cellular Component | TIM23 mitochondrial import inner membrane translocase complex | |
Molecular Function | Interleukin-2 receptor binding | |
Molecular Function | Protein serine/threonine phosphatase activity | |
Molecular Function | Protein tyrosine phosphatase activity | |
Molecular Function | Ribonucleoprotein complex binding | |
Biological Process | Mitochondrial membrane organization | |
Biological Process | Protein transport | |
Biological Process | Release of cytochrome c from mitochondria |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a244 | Homo sapiens | 0.0 | 691 | undefined |
| LLPS-Mum-a242 | Mus musculus | 0.0 | 619 | undefined |