• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caj-3404
CTPS1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: CTP synthase; UTP--ammonia ligase
Gene Name: CTPS1
Ensembl Gene: ENSCJAG00000003003.3
Ensembl Protein: ENSCJAP00000045120.2
Organism: Callithrix jacchus
Taxa ID: 9483
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKYILVTGGV  ISGIGKGIIA  SSVGTILKSC  GLHVTSIKID  PYINIDAGTF  SPYEHGEVFV  60
61    LDDGGEVDLD  LGNYERFLDI  RLTKDNNLTT  GKIYQYVINK  ERKGDYLGKT  VQVVPHITDA  120
121   IQEWVMRQAL  IPVDEDGLEP  QVCVIELGGT  VGDIESMPFI  EAFRQFQFKV  KRENFCNIHV  180
181   SLVPQPSSTG  EQKTKPTQNS  VRELRGLGLS  PDLVVCRCSN  PLDTSVKEKI  SMFCHVEPEQ  240
241   VICVHDVSSI  YRVPLLLEEQ  GVVDYFLRRL  DLPIERQPRK  MLMKWKEMAD  RYDRLLETCS  300
301   IALVGKYTKF  SDSYASVIKA  LEHSALAINH  KLEIKYIDST  DLEPNTSREE  PVRYHEAWQK  360
361   LCSAHGVLVP  GGFGVRGTEG  KIQAISWARN  QKKPFLGVCL  GMQLAVVEFS  RNVLGWEEAE  420
421   FCSWCLFSEH  LQVVDMPEHN  PGQMGGTMRL  GKRRTLFQTK  NSVMRKLYGD  ADYLEERHRH  480
481   RFEVNPVLKK  CLEEQGLKFV  GQDVEGERME  IVELEDHPFF  VGVQYHPEFL  SRPIKPSPPY  540
541   FGLLLASVGR  LPHYLQKGCR  LSFWWETMNK  PSEFYRDTYS  DRSGSSSPDS  EITDLKFPSI  600
601   NHD  603
Nucleotide CDS Sequence (FASTA)
1     ATGAAGTACA  TTCTGGTTAC  TGGTGGTGTT  ATATCAGGAA  TTGGAAAAGG  AATCATTGCC  60
61    AGCAGTGTGG  GCACAATACT  CAAGTCATGT  GGTTTACATG  TAACTTCAAT  CAAAATTGAC  120
121   CCTTACATTA  ACATTGATGC  AGGAACATTC  TCTCCTTATG  AGCATGGTGA  GGTTTTTGTG  180
181   CTGGACGATG  GTGGGGAAGT  AGATCTTGAC  CTGGGTAACT  ATGAGCGGTT  CCTTGACATC  240
241   CGCCTCACCA  AGGACAATAA  TCTGACCACT  GGAAAGATAT  ACCAGTATGT  CATTAACAAG  300
301   GAACGGAAAG  GAGATTACTT  GGGGAAAACT  GTCCAAGTTG  TCCCTCATAT  CACAGATGCA  360
361   ATCCAGGAGT  GGGTGATGAG  ACAGGCACTA  ATACCTGTAG  ATGAAGATGG  CCTGGAACCC  420
421   CAAGTGTGTG  TTATTGAGCT  TGGTGGAACT  GTGGGAGACA  TAGAAAGCAT  GCCCTTTATT  480
481   GAGGCCTTCC  GTCAGTTCCA  ATTCAAGGTC  AAAAGAGAGA  ACTTTTGTAA  CATCCACGTC  540
541   AGTCTAGTTC  CCCAGCCGAG  TTCAACAGGG  GAACAGAAGA  CTAAACCCAC  CCAGAACAGT  600
601   GTTCGGGAAC  TTAGAGGGCT  TGGGCTTTCC  CCAGATCTGG  TTGTATGCAG  GTGCTCAAAT  660
661   CCACTTGACA  CATCAGTGAA  AGAGAAAATA  TCAATGTTCT  GCCATGTCGA  GCCTGAACAA  720
721   GTGATCTGTG  TCCATGATGT  CTCATCCATC  TACCGAGTCC  CCTTGTTGTT  AGAGGAGCAA  780
781   GGCGTTGTAG  ATTATTTTCT  TCGAAGACTT  GACCTGCCTA  TTGAGAGGCA  GCCAAGAAAA  840
841   ATGCTGATGA  AATGGAAAGA  GATGGCTGAC  AGATACGATC  GCTTGCTAGA  GACCTGCTCT  900
901   ATTGCCCTTG  TGGGCAAATA  CACGAAGTTC  TCAGACTCCT  ATGCCTCTGT  CATTAAGGCT  960
961   CTGGAGCATT  CTGCACTGGC  CATCAACCAC  AAATTGGAAA  TCAAGTATAT  AGATTCTACG  1020
1021  GACTTGGAGC  CCAATACCTC  GCGGGAAGAG  CCCGTGCGCT  ACCACGAAGC  TTGGCAGAAG  1080
1081  CTCTGTAGTG  CTCATGGAGT  GCTGGTTCCA  GGAGGATTTG  GTGTTCGAGG  AACAGAAGGA  1140
1141  AAAATCCAAG  CAATTTCCTG  GGCTCGGAAT  CAGAAAAAGC  CTTTTTTGGG  CGTTTGCTTG  1200
1201  GGAATGCAGT  TGGCAGTGGT  TGAATTCTCA  AGAAACGTGC  TGGGATGGGA  AGATGCCAAT  1260
1261  TCTACAGAGT  TTGACCCTAA  GACCAGTCAT  CCCGTGGTCG  TAGACATGCC  AGAACACAAC  1320
1321  CCAGGGCAGA  TGGGCGGAAC  CATGAGGCTG  GGCAAGAGGA  GAACCCTGTT  CCAGACCAAG  1380
1381  AACTCAGTCA  TGAGGAAACT  GTATGGAGAT  GCAGACTACT  TGGAAGAGAG  GCACCGCCAC  1440
1441  CGATTTGAGG  TGAATCCAGT  CTTGAAGAAG  TGTTTGGAAG  AACAAGGCCT  GAAGTTCGTT  1500
1501  GGCCAAGATG  TTGAAGGAGA  GAGAATGGAA  ATTGTGGAGT  TGGAAGATCA  TCCCTTTTTT  1560
1561  GTTGGGGTTC  AGTACCACCC  TGAGTTCCTG  TCCAGACCTA  TCAAGCCCTC  CCCACCATAC  1620
1621  TTTGGCCTCC  TCCTGGCCTC  TGTGGGGCGA  CTCCCACATT  ACCTCCAGAA  AGGCTGCAGG  1680
1681  CTGTCGCCCA  GGGACACCTA  TAGTGACAGA  AGTGGAAGCA  GCTCCCCTGA  CTCTGAGATT  1740
1741  ACTGATCTGA  AGTTTCCGTC  AATAAATCAT  GACTGA  1776

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
Glutamine amidotransferase
Ligase
Nucleotide-binding
Pyrimidine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoophidium
Molecular Function
ATP binding
Molecular Function
CTP synthase activity
Molecular Function
Identical protein binding
Biological Process
'de novo' CTP biosynthetic process
Biological Process
B cell proliferation
Biological Process
Glutamine metabolic process
Biological Process
T cell proliferation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-0885Pan troglodytes95.70.01069
LLPS-Pap-0100Pan paniscus95.70.01069
LLPS-Aon-1562Aotus nancymaae95.020.01058
LLPS-Gog-1305Gorilla gorilla94.030.01045
LLPS-Hos-1793Homo sapiens94.030.01045
LLPS-Nol-1560Nomascus leucogenys94.030.01044
LLPS-Cea-2239Cercocebus atys93.860.01042
LLPS-Chs-1985Chlorocebus sabaeus93.860.01042
LLPS-Maf-3671Macaca fascicularis93.860.01042
LLPS-Paa-2541Papio anubis93.860.01042
LLPS-Mal-0567Mandrillus leucophaeus93.860.01042
LLPS-Bot-1995Bos taurus93.860.01045
LLPS-Man-1366Macaca nemestrina93.860.01042
LLPS-Mam-2769Macaca mulatta93.860.01042
LLPS-Poa-1287Pongo abelii93.860.01044
LLPS-Mup-0903Mustela putorius furo93.70.01042
LLPS-Ova-1494Ovis aries93.70.01044
LLPS-Rhb-1359Rhinopithecus bieti93.70.01040
LLPS-Otg-1431Otolemur garnettii93.530.01045
LLPS-Fec-0275Felis catus93.530.01041
LLPS-Caf-3004Canis familiaris93.530.01041
LLPS-Sus-1472Sus scrofa93.370.01038
LLPS-Aim-1534Ailuropoda melanoleuca93.370.01037
LLPS-Dio-0414Dipodomys ordii93.370.01044
LLPS-Mum-3315Mus musculus93.20.01040
LLPS-Myl-2512Myotis lucifugus93.20.01040
LLPS-Cas-0344Carlito syrichta93.20.01040
LLPS-Eqc-2763Equus caballus93.20.01039
LLPS-Mea-2454Mesocricetus auratus92.870.01035
LLPS-Ran-0438Rattus norvegicus92.870.01038
LLPS-Tut-2449Tursiops truncatus92.870.01025
LLPS-Mod-0481Monodelphis domestica92.870.01033
LLPS-Sah-0597Sarcophilus harrisii92.540.01030
LLPS-Fud-1285Fukomys damarensis91.870.01031
LLPS-Loa-0722Loxodonta africana91.40.01015
LLPS-Urm-3314Ursus maritimus91.40.01009
LLPS-Cap-0705Cavia porcellus90.880.01022
LLPS-Ora-0483Ornithorhynchus anatinus90.050.01006
LLPS-Gaga-1682Gallus gallus89.880.0 996
LLPS-Tag-0721Taeniopygia guttata89.720.01004
LLPS-Fia-1264Ficedula albicollis89.550.01003
LLPS-Meg-2645Meleagris gallopavo88.740.0 939
LLPS-Anc-0420Anolis carolinensis87.890.0 986
LLPS-Pes-3211Pelodiscus sinensis87.240.0 828
LLPS-Orc-2514Oryctolagus cuniculus87.060.0 941
LLPS-Orn-0242Oreochromis niloticus84.160.0 886
LLPS-Leo-0675Lepisosteus oculatus83.910.0 949
LLPS-Scf-0999Scleropages formosus83.810.0 927
LLPS-Xim-0625Xiphophorus maculatus83.810.0 910
LLPS-Xet-1707Xenopus tropicalis83.770.0 943
LLPS-Pof-3154Poecilia formosa83.30.0 901
LLPS-Dar-2974Danio rerio82.750.0 931
LLPS-Icp-0444Ictalurus punctatus82.740.0 897
LLPS-Orl-3087Oryzias latipes82.740.0 891
LLPS-Asm-1171Astyanax mexicanus82.530.0 927
LLPS-Scm-2419Scophthalmus maximus81.590.0 916
LLPS-Tar-0121Takifugu rubripes81.430.0 918
LLPS-Lac-0326Latimeria chalumnae80.530.0 890
LLPS-Ten-2481Tetraodon nigroviridis80.530.0 905
LLPS-Gaa-1522Gasterosteus aculeatus79.440.0 895
LLPS-Anp-1088Anas platyrhynchos77.220.0 849
LLPS-Ict-0345Ictidomys tridecemlineatus75.80.0 822
LLPS-Cii-1306Ciona intestinalis72.341e-1481.3
LLPS-Drm-2201Drosophila melanogaster66.430.0 713
LLPS-Abg-0386Absidia glauca61.830.0 645
LLPS-Cis-0032Ciona savignyi61.360.0 701
LLPS-Php-2049Physcomitrella patens60.070.0 613
LLPS-Viv-1269Vitis vinifera60.040.0 595
LLPS-Dac-1425Daucus carota59.750.0 597
LLPS-Sem-0584Selaginella moellendorffii59.740.0 583
LLPS-Sol-0641Solanum lycopersicum59.390.0 588
LLPS-Nia-1784Nicotiana attenuata59.320.0 587
LLPS-Via-2368Vigna angularis59.310.0 585
LLPS-Amt-2261Amborella trichopoda59.240.0 597
LLPS-Phv-0477Phaseolus vulgaris59.120.0 581
LLPS-Sob-0316Sorghum bicolor59.10.0 590
LLPS-Mae-2133Manihot esculenta58.960.0 590
LLPS-Gor-2196Gossypium raimondii58.790.0 595
LLPS-Mua-1749Musa acuminata58.710.0 584
LLPS-Cus-0365Cucumis sativus58.710.0 582
LLPS-Ori-1592Oryza indica58.650.0 598
LLPS-Ors-1833Oryza sativa58.650.0 597
LLPS-Org-2079Oryza glaberrima58.650.0 597
LLPS-Prp-0783Prunus persica58.630.0 589
LLPS-Orr-0385Oryza rufipogon58.570.0 581
LLPS-Coc-1341Corchorus capsularis58.570.0 585
LLPS-Glm-2562Glycine max58.530.0 602
LLPS-Tra-0874Triticum aestivum58.530.0 592
LLPS-Brd-0862Brachypodium distachyon58.50.0 593
LLPS-Lep-1579Leersia perrieri58.470.0 593
LLPS-Sac-0023Saccharomyces cerevisiae58.450.0 599
LLPS-Orni-2224Oryza nivara58.390.0 592
LLPS-Orgl-1519Oryza glumaepatula58.390.0 592
LLPS-Orm-0563Oryza meridionalis58.390.0 590
LLPS-Arl-1758Arabidopsis lyrata58.360.0 583
LLPS-Zem-1649Zea mays58.360.0 592
LLPS-Orbr-0784Oryza brachyantha58.350.0 587
LLPS-Crn-1100Cryptococcus neoformans58.320.0 604
LLPS-Scp-1118Schizosaccharomyces pombe58.290.0 601
LLPS-Yal-1152Yarrowia lipolytica58.210.0 608
LLPS-Brn-2300Brassica napus58.190.0 579
LLPS-Brr-2316Brassica rapa58.190.0 578
LLPS-Bro-2815Brassica oleracea58.190.0 578
LLPS-Thc-0464Theobroma cacao58.170.0 578
LLPS-Sot-1028Solanum tuberosum58.140.0 597
LLPS-Miv-0800Microbotryum violaceum58.130.0 600
LLPS-Chr-0284Chlamydomonas reinhardtii58.110.0 590
LLPS-Met-1447Medicago truncatula58.020.0 594
LLPS-Pot-0587Populus trichocarpa57.990.0 592
LLPS-Orp-0451Oryza punctata57.860.0 581
LLPS-Asg-0630Ashbya gossypii57.790.0 606
LLPS-Hea-0627Helianthus annuus57.740.0 598
LLPS-Hov-0762Hordeum vulgare57.680.0 585
LLPS-Ast-0178Aspergillus terreus57.510.0 557
LLPS-Tru-1996Triticum urartu57.50.0 584
LLPS-Mel-0255Melampsora laricipopulina57.40.0 561
LLPS-Art-2157Arabidopsis thaliana57.370.0 572
LLPS-Scc-1552Schizosaccharomyces cryophilus57.30.0 591
LLPS-Asni-0665Aspergillus niger57.190.0 557
LLPS-Sei-1109Setaria italica57.190.0 583
LLPS-Orb-0864Oryza barthii57.010.0 577
LLPS-Asc-0543Aspergillus clavatus56.790.0 560
LLPS-Asfu-0662Aspergillus fumigatus56.660.0 560
LLPS-Kop-0752Komagataella pastoris56.590.0 587
LLPS-Mao-0605Magnaporthe oryzae56.510.0 548
LLPS-Nef-0712Neosartorya fischeri56.480.0 553
LLPS-Gag-0056Gaeumannomyces graminis56.250.0 546
LLPS-Osl-0918Ostreococcus lucimarinus55.580.0 552
LLPS-Blg-0572Blumeria graminis55.20.0 559
LLPS-Ved-1101Verticillium dahliae55.140.0 549
LLPS-Vir-0559Vigna radiata55.010.0 582
LLPS-Fus-0855Fusarium solani54.960.0 546
LLPS-Asn-0932Aspergillus nidulans54.640.0 541
LLPS-Lem-0573Leptosphaeria maculans54.210.0 555
LLPS-Pyt-0548Pyrenophora teres54.210.0 550
LLPS-Nec-1361Neurospora crassa53.710.0 543
LLPS-Usm-0070Ustilago maydis53.530.0 585
LLPS-Spr-0096Sporisorium reilianum52.950.0 580
LLPS-Pytr-1332Pyrenophora triticirepentis52.820.0 542