• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Caf-a858
LOC100683871

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: ATP synthase subunit d, mitochondrial
Gene Name: LOC100683871
Ensembl Gene: ENSCAFG00000000808.2
Ensembl Protein: ENSCAFP00000036047.1
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION


Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblENSCAFT00000001266.2ENSCAFP00000036047.1
UniProtE2RHH8, E2RHH8_CANLF
GeneBankAAEX03016047, AAEX03006301

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAGRKLALKT  IDWVAFGEII  PRNQKAIANS  LKSWNEMLTS  RLATLPEKPP  AIDWAYYKAN  60
61    VAKAGLVDDF  EKKFNALKVP  VPEDKYTVQV  DAEEKEDVKS  CAEFLSLSKA  RIEEYEKELE  120
121   KMKNIIPFDQ  MTIEDLNEVF  PETKLDKKKY  PYWPHKPIEN  L  161
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGGGC  GAAAACTTGC  TCTAAAAACC  ATTGACTGGG  TAGCTTTTGG  GGAGATCATA  60
61    CCCCGAAACC  AGAAGGCCAT  TGCCAACTCC  TTGAAATCCT  GGAATGAGAT  GCTTACCTCC  120
121   AGGTTGGCTA  CTCTTCCTGA  GAAACCACCT  GCTATCGACT  GGGCTTACTA  CAAGGCCAAT  180
181   GTGGCAAAGG  CTGGCTTGGT  AGATGACTTT  GAGAAGAAGT  TTAATGCCCT  GAAGGTTCCT  240
241   GTGCCAGAGG  ATAAATACAC  TGTCCAGGTG  GATGCTGAGG  AAAAAGAAGA  TGTGAAAAGC  300
301   TGTGCTGAGT  TTTTGTCCCT  CTCAAAGGCC  AGGATTGAAG  AATATGAAAA  AGAGCTGGAG  360
361   AAGATGAAGA  ACATAATTCC  ATTTGATCAG  ATGACCATTG  AGGACCTGAA  TGAAGTCTTC  420
421   CCAGAAACCA  AATTAGACAA  GAAGAAGTAT  CCTTATTGGC  CTCACAAGCC  AATTGAAAAT  480
481   TTATAA  486

▼ KEYWORD


ID
Family
Coiled coil
Complete proteome
Hydrogen ion transport
Ion transport
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Transport

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Mitochondrial proton-transporting ATP synthase, stator stalk
Molecular Function
Proton transmembrane transporter activity
Biological Process
ATP hydrolysis coupled cation transmembrane transport
Biological Process
ATP synthesis coupled proton transport

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-a894Homo sapiens5e-103301undefined