LLPS-Caf-a589
CDH11
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Cadherin 11 |
| Gene Name: | CDH11 |
| Ensembl Gene: | ENSCAFG00000020425.3 |
| Ensembl Protein: | ENSCAFP00000030296.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Cadherins are calcium-dependent cell adhesion proteins. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000032530.3 | ENSCAFP00000030296.3 |
| UniProt | F1P6U6, F1P6U6_CANLF | |
| GeneBank | AAEX03004156 | |
| RefSeq | XM_005620881.2, XM_005620882.1, XM_536826.5 | XP_005620938.1, XP_005620939.1, XP_536826.2 |
| Entrez | 479696 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKEHYCLQAA LVCLGVLCHS QAMATERRSH LRPSFHGHHE KGKEGQVLQR SKRGWVWNQF 60 61 FVIEEYTGPD PVLVGRLHSD IDSGDGNIKY ILSGEGAGTI FVIDDKSGNI HATKTLDREE 120 121 RAQYTLMAQA VDRDTNRPLE PPSEFIVKVQ DINDNPPEFL HETYHANVPE RSNVGTSVIQ 180 181 VTASDADDPT YGNSAKLVYS ILEGQPYFSV EAQTGIIRTA LPNMDREAKE EYHVVIQAKD 240 241 MGGHMGGLSG TTKVTITLTD VNDNPPKFPQ SVYQMSVSEA AVPGEEVGRV KAKDPDIGEN 300 301 GLVTYNIVDG DGMELFEITT DYETQEGVVK LKKPVDFETK RAYSLKVEAA NVHIDPKFIS 360 361 NGPFKDTVTV KIAVEDADEP PMFLAPSYIH EVQENAAAGT VVGRVHAKDP DAANSPIRYS 420 421 IDRHTDLDRF FTINPEDGFI KTTKPLDREE TAWLNISVFA AEIHNRHQEA KVPVAIRVLD 480 481 VNDNAPKFAA PYEGFICESD QTKPLSNQPI VTISADDKDD TANGPRFIFS LPPEIIHNPN 540 541 FTVRDNRDST AGVYARRGGF SRQKQDLYLL PVVISDGGIP PMSSTNTLTI KVCGCDVHGA 600 601 LLSCNAEAYV LNAGLSTGAL IAILACIVIL LVIVVLFVTL RRQKKEPLIV FEEEDVRENI 660 661 ITYDDEGGGE EDTEAFDIAT LQNPDGINGF IPRKDIKPEY QYMPRPGLRP APNSVDVDDF 720 721 INTRIQEADN DPTAPPYDSI QIYGYEGRGS VAGSLSSLES ATTDSDLDYD YLQNWGPRFK 780 781 KLADLYGSKD TFDDDS 796 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAGGAGC ACTACTGTTT ACAAGCCGCC CTGGTGTGCC TGGGCGTGCT GTGCCACAGC 60 61 CAGGCCATGG CCACAGAGCG GCGGAGCCAC CTGCGCCCCT CGTTCCACGG GCACCACGAG 120 121 AAGGGCAAGG AGGGGCAGGT GCTGCAGCGC TCCAAGAGAG GCTGGGTCTG GAACCAGTTC 180 181 TTCGTGATAG AGGAGTACAC CGGGCCTGAC CCCGTGCTCG TGGGCAGGCT TCATTCCGAT 240 241 ATTGACTCTG GTGATGGGAA CATTAAATAC ATTCTCTCAG GTGAAGGAGC CGGGACCATT 300 301 TTTGTGATTG ATGACAAATC AGGGAACATT CATGCCACCA AGACACTGGA CCGAGAGGAG 360 361 AGAGCCCAGT ACACCCTCAT GGCTCAGGCG GTGGACAGGG ACACCAACCG GCCGCTGGAG 420 421 CCACCATCGG AGTTCATCGT CAAGGTCCAG GACATTAACG ACAACCCTCC TGAGTTCCTG 480 481 CACGAGACCT ATCACGCGAA CGTGCCTGAG AGGTCCAACG TGGGAACGTC GGTCATCCAG 540 541 GTGACCGCTT CAGATGCCGA TGATCCTACG TACGGAAACA GCGCCAAGTT AGTGTACAGT 600 601 ATCCTGGAAG GACAGCCCTA CTTTTCAGTG GAAGCGCAGA CAGGTATCAT CAGGACAGCC 660 661 CTTCCCAACA TGGACAGGGA AGCCAAGGAG GAGTACCACG TGGTGATCCA GGCCAAGGAC 720 721 ATGGGTGGAC ACATGGGTGG CCTCTCAGGG ACAACCAAAG TGACGATCAC ACTGACTGAT 780 781 GTCAATGACA ACCCACCAAA GTTTCCGCAG AGCGTGTACC AGATGTCTGT GTCAGAAGCG 840 841 GCTGTCCCCG GGGAAGAAGT AGGAAGAGTA AAGGCAAAAG ACCCAGACAT TGGAGAAAAT 900 901 GGCTTAGTCA CATACAATAT TGTTGATGGA GACGGTATGG AATTGTTTGA GATCACGACG 960 961 GACTATGAGA CACAGGAGGG CGTGGTCAAA CTGAAAAAGC CCGTAGATTT TGAAACCAAA 1020 1021 AGAGCATACA GCTTGAAGGT AGAGGCGGCC AACGTGCACA TTGACCCGAA GTTCATCAGC 1080 1081 AACGGGCCTT TCAAGGACAC TGTGACGGTG AAGATTGCAG TGGAAGACGC TGATGAGCCC 1140 1141 CCCATGTTCT TGGCTCCGAG TTACATCCAT GAAGTCCAAG AAAATGCAGC CGCTGGCACT 1200 1201 GTGGTTGGGA GAGTGCATGC CAAAGACCCT GATGCTGCCA ACAGCCCCAT AAGGTATTCA 1260 1261 ATCGATCGTC ATACTGACCT CGACAGGTTT TTCACTATTA ATCCAGAAGA CGGTTTTATT 1320 1321 AAAACCACGA AACCTTTGGA CAGAGAGGAA ACCGCCTGGC TCAACATATC CGTTTTTGCA 1380 1381 GCAGAAATCC ACAATAGGCA TCAGGAAGCC AAAGTCCCGG TGGCCATCAG GGTCCTTGAT 1440 1441 GTCAATGATA ACGCTCCCAA GTTTGCTGCC CCTTATGAAG GCTTCATCTG TGAGAGTGAT 1500 1501 CAGACCAAGC CACTTTCTAA CCAGCCAATT GTCACAATTA GTGCAGATGA CAAGGATGAC 1560 1561 ACAGCCAATG GACCAAGATT TATCTTCAGT CTACCCCCTG AAATCATTCA CAATCCAAAT 1620 1621 TTCACAGTCA GAGACAACAG AGACAGCACG GCCGGCGTGT ACGCCCGGCG CGGGGGCTTC 1680 1681 AGCCGCCAGA AGCAGGACCT GTACCTGCTG CCCGTGGTCA TCAGCGACGG CGGGATCCCG 1740 1741 CCCATGAGCA GCACCAACAC CCTGACCATC AAAGTGTGCG GGTGCGACGT GCACGGGGCG 1800 1801 CTGCTCTCCT GCAACGCCGA GGCCTACGTG CTGAACGCCG GCCTCAGCAC CGGCGCGCTC 1860 1861 ATCGCCATCC TCGCCTGCAT CGTCATCCTG CTGGTGATCG TAGTGCTGTT TGTGACCCTG 1920 1921 AGAAGGCAAA AGAAAGAACC GCTCATCGTC TTTGAGGAGG AAGACGTCCG TGAGAACATC 1980 1981 ATCACGTACG ACGACGAAGG GGGTGGGGAG GAAGACACAG AAGCCTTTGA TATTGCCACC 2040 2041 CTCCAGAATC CAGACGGGAT CAATGGCTTC ATCCCTCGCA AAGACATAAA ACCCGAGTAT 2100 2101 CAGTACATGC CTAGACCCGG GCTCCGGCCG GCACCCAACA GCGTGGACGT CGATGACTTC 2160 2161 ATCAATACGA GAATACAGGA GGCGGATAAT GACCCCACTG CCCCTCCTTA TGATTCAATC 2220 2221 CAAATCTACG GTTACGAAGG CAGGGGCTCG GTGGCCGGGT CCCTGAGCTC CCTAGAGTCG 2280 2281 GCCACCACAG ATTCGGACTT GGACTATGAC TACCTACAGA ACTGGGGACC TCGTTTTAAG 2340 2341 AAACTAGCAG ACTTGTACGG TTCCAAAGAC ACTTTTGATG ACGACTCTTA A 2391 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Catenin complex | |
Cellular Component | Cell surface | |
Cellular Component | Cell-cell adherens junction | |
Cellular Component | Cytoplasm | |
Cellular Component | Glutamatergic synapse | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plasma membrane | |
Cellular Component | Schaffer collateral - CA1 synapse | |
Molecular Function | Cadherin binding | |
Molecular Function | Calcium ion binding | |
Molecular Function | Cytoskeletal protein binding | |
Molecular Function | Protein homodimerization activity | |
Biological Process | Adherens junction organization | |
Biological Process | Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | |
Biological Process | Cell morphogenesis | |
Biological Process | Cell-cell adhesion | |
Biological Process | Cell-cell adhesion mediated by cadherin | |
Biological Process | Cell-cell junction assembly | |
Biological Process | Corticospinal tract morphogenesis | |
Biological Process | Homophilic cell adhesion via plasma membrane adhesion molecules | |
Biological Process | Modulation of chemical synaptic transmission |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a610 | Homo sapiens | 0.0 | 1619 | undefined |
| LLPS-Mum-a605 | Mus musculus | 0.0 | 1600 | undefined |