LLPS-Caf-4379
HEPH
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Hephaestin |
| Gene Name: | HEPH |
| Ensembl Gene: | ENSCAFG00000016633.3 |
| Ensembl Protein: | ENSCAFP00000024484.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000026362.3 | ENSCAFP00000024484.3 |
| UniProt | F1P7M1, F1P7M1_CANLF | |
| GeneBank | AAEX03026452, AAEX03026449, AAEX03026451, AAEX03026453, AAEX03026450 | |
| RefSeq | XM_005641425.2 | XP_005641482.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MFLELKGVRV MWAMEPGHLF WALLLMQPLW PQWTDGATRV YYLGIQDVQW NYAPKGRNVI 60 61 MDKPLDNDTV ASSFLKSDKN RIGSNYKKTI YKEYRDGSYM DEMVQPAWLG FLGPVLQAEV 120 121 GDVILIHLKN FATRPYTIHP HGVFYEKDSE GSLYPDGSSG QLKADDSVPP GGSHIYNWTI 180 181 PEGHAPTDAD PACLTWIYHS HVDAPRDIAT GLIGPLITCK RGTLDGNSPP QRKDVDNDFF 240 241 LLFSVVDENL SWHIDENIAT YCSDPTSVDK EDEAFQESNR MHAINGFVFG NLPDLSMCAQ 300 301 KRVAWHLFGM GNEVDVHTAF FHGQILTIRG HRTDVAHIFP ATFVTAEMVP REPGTWLISC 360 361 QVNSHFRDGM QALYKVKSCS MTPPMNQLTG KVRQYFIEAH EILWDYGPMG HDGSTGKNLR 420 421 EPGSGSDKFF QKGSSRIGGT YWKVRYEAFQ DETFQEKVQL EENKHLGILG PVIRAEVGDT 480 481 IQVIFYNRAS QPFSIQPHGV FYEKDYEGTV YNDGSSYTGL VARPFEKVTY RWTVPSHAGP 540 541 AAQDPACLTW MYFSAADPIR DTNSGLVGPL LVCRAGALDA DGKQKGVDKE FFLLFTVLDE 600 601 NKSWYSNANQ AAAMLDSRLL SEDVKGFQDS NQMHAINGFL FSNLPSLDMC KGDTVAWHLL 660 661 GLGTETDVHG VIFQGNTVKL QGMRKSAAML FPHTFVMAIM QPDNAGMFEI YCQAGSHRES 720 721 GMKAVYNVSQ CPGNQANHHQ RYQAARIYYI MAEEVEWDYC PDRSWELEWH NQSEKDSYGH 780 781 IFLSNQNGLL GSRYKKAVFR EYTDGTFKIP RPRTGPEEHL GILGPLLRGE IGDILTVVFK 840 841 NNASRPYSVH AHGVLESSTG WPLAAAPGEV LTYQWNIPER SGPGPNDSAC VSWIYYSAVD 900 901 PIKDMYSGLV GPLTICRKGT LEPYGGRNDM DREFALLFLI FDENQSWYLE ENVATHGPQE 960 961 PDHVNLQDDT FLESNKMHAI NGKLYSNLRG LTMYQGERVA WYMLAMGQDI DLHTVHFHAE 1020 1021 SFLYRNGESY RADVVDLFPG TFEVVEMVAS NPGTWLMHCH VSDHVHAGME TLFTVLSEKE 1080 1081 HVSTITTTTK EIGKATILRD IGEGNVRMLG MHIPIKNIDM LASVLISMSA ILLLIALALG 1140 1141 GVVWYQHRQR KLRRNRRSIL DDSFKLLSLK Q 1171 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTTCTTG AACTGAAAGG GGTCAGGGTA ATGTGGGCCA TGGAACCAGG CCATCTCTTC 60 61 TGGGCTCTTT TGTTGATGCA ACCTTTGTGG CCCCAATGGA CAGACGGGGC CACTCGAGTC 120 121 TACTACTTGG GCATCCAGGA TGTGCAGTGG AACTATGCTC CCAAGGGAAG AAATGTCATC 180 181 ATGGACAAGC CTCTGGACAA CGACACAGTA GCTTCCAGCT TCCTAAAATC TGACAAGAAT 240 241 CGGATAGGAA GCAACTACAA GAAGACCATT TACAAGGAAT ACAGAGATGG CTCATACATG 300 301 GATGAAATGG TCCAGCCTGC TTGGTTGGGC TTCTTGGGGC CAGTGTTGCA GGCTGAGGTG 360 361 GGAGATGTCA TCCTTATCCA CCTGAAGAAT TTTGCCACTC GTCCCTATAC CATCCATCCC 420 421 CATGGTGTTT TCTATGAAAA GGACTCAGAA GGCTCCCTAT ACCCAGATGG CTCCTCTGGT 480 481 CAACTAAAAG CTGATGACTC TGTTCCCCCG GGAGGCAGCC ACATTTACAA CTGGACCATT 540 541 CCAGAAGGCC ATGCACCCAC TGATGCTGAC CCAGCATGCC TCACCTGGAT CTACCATTCT 600 601 CATGTAGATG CTCCACGAGA CATTGCGACT GGCCTCATTG GACCCCTTAT CACGTGTAAA 660 661 AGAGGAACTC TGGATGGAAA TTCCCCTCCT CAGCGGAAGG ATGTGGATAA TGATTTCTTC 720 721 CTGCTCTTCA GTGTAGTAGA TGAGAACCTT AGCTGGCATA TTGATGAGAA CATTGCCACT 780 781 TACTGCTCAG ATCCTACCTC AGTAGACAAA GAAGATGAGG CCTTTCAGGA AAGCAATAGG 840 841 ATGCATGCAA TCAATGGCTT TGTGTTTGGG AACTTACCAG ATCTAAGCAT GTGTGCACAG 900 901 AAGCGTGTGG CCTGGCACTT GTTTGGCATG GGCAATGAAG TAGATGTCCA CACAGCTTTC 960 961 TTCCATGGAC AGATCCTAAC TATCCGGGGC CACCGCACTG ATGTGGCTCA CATCTTTCCA 1020 1021 GCCACTTTTG TGACAGCTGA GATGGTGCCC CGGGAACCTG GCACCTGGTT GATTAGCTGT 1080 1081 CAAGTGAATA GTCACTTTCG AGATGGCATG CAAGCACTCT ACAAGGTCAA GTCTTGCTCT 1140 1141 ATGACCCCTC CTATGAACCA ACTCACAGGC AAAGTTCGGC AGTACTTCAT TGAGGCCCAT 1200 1201 GAGATTCTAT GGGACTATGG CCCGATGGGG CATGATGGAA GTACTGGGAA GAATTTGAGG 1260 1261 GAACCAGGCA GTGGCTCAGA TAAATTCTTC CAGAAGGGCT CCAGTCGGAT TGGGGGCACT 1320 1321 TACTGGAAAG TCCGATATGA AGCCTTCCAA GATGAGACAT TCCAGGAAAA GGTGCAGCTG 1380 1381 GAAGAAAATA AGCATCTTGG AATACTGGGG CCAGTGATCC GGGCTGAGGT GGGTGACACC 1440 1441 ATCCAGGTGA TCTTTTACAA CCGCGCTTCC CAACCATTCA GCATACAGCC TCATGGAGTC 1500 1501 TTCTATGAAA AAGACTACGA GGGAACTGTG TACAATGATG GCTCATCCTA CACTGGCTTG 1560 1561 GTGGCTAGGC CCTTTGAGAA AGTAACATAC CGCTGGACAG TCCCCTCCCA TGCTGGCCCT 1620 1621 GCTGCTCAGG ATCCAGCGTG TCTCACCTGG ATGTACTTCT CTGCTGCAGA TCCCATAAGA 1680 1681 GATACAAATT CGGGTCTGGT GGGCCCCCTG TTGGTGTGCA GGGCGGGTGC CTTGGATGCA 1740 1741 GATGGCAAAC AGAAAGGAGT GGATAAGGAA TTTTTTCTCC TTTTTACTGT GTTGGATGAG 1800 1801 AACAAGAGCT GGTACAGCAA TGCCAATCAA GCAGCTGCTA TGTTGGATTC TCGACTGCTC 1860 1861 TCAGAGGATG TCAAGGGTTT CCAAGATTCC AATCAGATGC ATGCCATTAA TGGGTTTCTG 1920 1921 TTCTCTAACC TGCCCAGCCT GGACATGTGC AAGGGTGATA CAGTGGCCTG GCATTTGCTT 1980 1981 GGTTTGGGCA CAGAGACTGA CGTGCATGGA GTCATATTCC AGGGCAACAC AGTGAAGCTT 2040 2041 CAGGGCATGA GGAAGAGTGC AGCCATGCTC TTTCCTCATA CCTTTGTCAT GGCCATCATG 2100 2101 CAGCCTGACA ATGCTGGGAT GTTTGAGATT TACTGCCAGG CAGGCAGCCA TAGAGAATCA 2160 2161 GGGATGAAGG CAGTCTATAA TGTCTCCCAG TGTCCTGGCA ACCAAGCCAA CCATCACCAA 2220 2221 CGATACCAGG CTGCAAGAAT CTACTACATC ATGGCAGAAG AGGTAGAGTG GGACTATTGC 2280 2281 CCTGACAGGA GCTGGGAACT GGAATGGCAC AACCAGTCTG AGAAGGACAG TTATGGTCAC 2340 2341 ATTTTCCTGA GCAACCAGAA TGGGCTCCTT GGTTCCAGAT ACAAGAAAGC TGTATTCAGA 2400 2401 GAATACACTG ATGGTACATT CAAGATCCCT CGGCCAAGAA CTGGACCCGA GGAACACCTG 2460 2461 GGAATATTAG GTCCACTTCT CAGAGGAGAG ATTGGTGATA TCCTAACTGT GGTGTTCAAG 2520 2521 AATAATGCCA GCCGCCCCTA TTCTGTGCAT GCCCATGGAG TGCTAGAATC TAGCACTGGT 2580 2581 TGGCCACTAG CCGCTGCACC TGGTGAGGTT CTCACATACC AATGGAACAT CCCAGAAAGA 2640 2641 TCTGGCCCAG GGCCCAATGA TTCTGCTTGT GTTTCCTGGA TCTATTATTC TGCAGTGGAT 2700 2701 CCCATCAAGG ACATGTATAG TGGCTTGGTT GGACCCTTGA CCATCTGCCG AAAGGGCACC 2760 2761 CTGGAGCCCT ATGGAGGACG GAATGACATG GACCGAGAAT TTGCTTTGTT ATTCTTAATC 2820 2821 TTTGATGAGA ACCAGTCTTG GTATCTGGAA GAGAATGTAG CAACCCATGG GCCCCAGGAG 2880 2881 CCAGACCATG TTAACCTACA GGATGATACT TTTCTGGAGA GCAATAAAAT GCATGCCATT 2940 2941 AATGGAAAGC TCTACAGCAA CCTCAGGGGG CTCACCATGT ACCAAGGAGA ACGAGTGGCC 3000 3001 TGGTATATGC TGGCCATGGG CCAAGATATT GACCTACACA CTGTCCACTT CCATGCAGAG 3060 3061 AGCTTCCTAT ATCGGAATGG AGAGAGCTAC CGGGCAGATG TGGTGGATCT GTTCCCAGGG 3120 3121 ACCTTTGAGG TTGTGGAGAT GGTAGCCAGC AACCCCGGGA CATGGCTGAT GCACTGCCAT 3180 3181 GTTTCTGATC ATGTCCATGC TGGCATGGAA ACCCTCTTTA CTGTCTTGTC CGAAAAAGAA 3240 3241 CATGTAAGCA CTATCACCAC CACCACCAAA GAGATTGGAA AAGCAACAAT CCTCAGAGAC 3300 3301 ATTGGAGAAG GCAATGTCAG GATGCTGGGC ATGCATATTC CCATAAAGAA TATTGATATG 3360 3361 TTGGCTTCTG TTTTAATTTC TATGAGTGCC ATTCTCCTGC TCATTGCTCT GGCTCTTGGT 3420 3421 GGTGTGGTCT GGTATCAGCA TCGGCAAAGA AAGCTACGAC GCAACAGGAG GTCCATCCTG 3480 3481 GATGACAGCT TCAAGCTTCT GTCCCTCAAG CAGTAA 3516 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-2010 | Ursus maritimus | 95.35 | 0.0 | 2269 |
| LLPS-Aim-3997 | Ailuropoda melanoleuca | 94.49 | 0.0 | 2249 |
| LLPS-Fec-4792 | Felis catus | 93.64 | 0.0 | 2243 |
| LLPS-Eqc-1688 | Equus caballus | 90.35 | 0.0 | 2178 |
| LLPS-Sus-3681 | Sus scrofa | 89.92 | 0.0 | 2159 |
| LLPS-Bot-2388 | Bos taurus | 89.68 | 0.0 | 2153 |
| LLPS-Myl-2988 | Myotis lucifugus | 89.63 | 0.0 | 2139 |
| LLPS-Ova-3767 | Ovis aries | 89.51 | 0.0 | 2147 |
| LLPS-Pap-3030 | Pan paniscus | 89.41 | 0.0 | 2142 |
| LLPS-Pat-1122 | Pan troglodytes | 89.13 | 0.0 | 2148 |
| LLPS-Aon-4572 | Aotus nancymaae | 89.13 | 0.0 | 2144 |
| LLPS-Mal-3492 | Mandrillus leucophaeus | 89.04 | 0.0 | 2150 |
| LLPS-Hos-2119 | Homo sapiens | 88.96 | 0.0 | 2144 |
| LLPS-Cea-3376 | Cercocebus atys | 88.96 | 0.0 | 2151 |
| LLPS-Chs-2467 | Chlorocebus sabaeus | 88.96 | 0.0 | 2148 |
| LLPS-Caj-0445 | Callithrix jacchus | 88.95 | 0.0 | 2119 |
| LLPS-Paa-1106 | Papio anubis | 88.87 | 0.0 | 2147 |
| LLPS-Gog-3458 | Gorilla gorilla | 88.87 | 0.0 | 2146 |
| LLPS-Mam-0564 | Macaca mulatta | 88.7 | 0.0 | 2147 |
| LLPS-Man-3704 | Macaca nemestrina | 88.7 | 0.0 | 2148 |
| LLPS-Maf-2777 | Macaca fascicularis | 88.7 | 0.0 | 2147 |
| LLPS-Loa-4223 | Loxodonta africana | 88.6 | 0.0 | 2111 |
| LLPS-Otg-3570 | Otolemur garnettii | 88.26 | 0.0 | 2112 |
| LLPS-Cas-2696 | Carlito syrichta | 88.2 | 0.0 | 2118 |
| LLPS-Orc-2458 | Oryctolagus cuniculus | 88.03 | 0.0 | 2132 |
| LLPS-Ict-4477 | Ictidomys tridecemlineatus | 87.68 | 0.0 | 2104 |
| LLPS-Poa-3364 | Pongo abelii | 87.42 | 0.0 | 2081 |
| LLPS-Mum-4240 | Mus musculus | 84.97 | 0.0 | 2048 |
| LLPS-Cap-3792 | Cavia porcellus | 84.69 | 0.0 | 2043 |
| LLPS-Dio-0172 | Dipodomys ordii | 84.63 | 0.0 | 2031 |
| LLPS-Ran-4895 | Rattus norvegicus | 84.37 | 0.0 | 2036 |
| LLPS-Fud-4284 | Fukomys damarensis | 84.32 | 0.0 | 2038 |
| LLPS-Nol-4428 | Nomascus leucogenys | 83.39 | 0.0 | 1998 |
| LLPS-Mea-3366 | Mesocricetus auratus | 78.57 | 1e-62 | 236 |
| LLPS-Sah-2049 | Sarcophilus harrisii | 73.37 | 0.0 | 1766 |
| LLPS-Mod-0341 | Monodelphis domestica | 66.41 | 0.0 | 1546 |
| LLPS-Gaga-2802 | Gallus gallus | 63.09 | 0.0 | 1504 |
| LLPS-Meg-3319 | Meleagris gallopavo | 62.95 | 0.0 | 1504 |
| LLPS-Anp-3315 | Anas platyrhynchos | 62.44 | 0.0 | 1496 |
| LLPS-Anc-1180 | Anolis carolinensis | 62.12 | 0.0 | 1440 |
| LLPS-Pes-0124 | Pelodiscus sinensis | 61.91 | 0.0 | 1491 |
| LLPS-Fia-2361 | Ficedula albicollis | 61.71 | 0.0 | 1479 |
| LLPS-Tag-2792 | Taeniopygia guttata | 61.23 | 0.0 | 1471 |
| LLPS-Lac-3467 | Latimeria chalumnae | 59.15 | 0.0 | 1381 |
| LLPS-Leo-3451 | Lepisosteus oculatus | 57.95 | 0.0 | 1315 |
| LLPS-Scf-0005 | Scleropages formosus | 53.82 | 0.0 | 1181 |
| LLPS-Dar-3978 | Danio rerio | 52.55 | 0.0 | 1159 |
| LLPS-Asm-3439 | Astyanax mexicanus | 52.52 | 0.0 | 1159 |
| LLPS-Icp-2012 | Ictalurus punctatus | 51.43 | 0.0 | 1144 |
| LLPS-Ora-1989 | Ornithorhynchus anatinus | 50.8 | 0.0 | 1000 |
| LLPS-Mup-2682 | Mustela putorius furo | 50.29 | 0.0 | 1084 |
| LLPS-Xet-2978 | Xenopus tropicalis | 49.95 | 0.0 | 1082 |
| LLPS-Orl-4101 | Oryzias latipes | 49.36 | 0.0 | 552 |
| LLPS-Ten-3155 | Tetraodon nigroviridis | 48.95 | 0.0 | 1025 |
| LLPS-Orn-3688 | Oreochromis niloticus | 47.69 | 0.0 | 1021 |
| LLPS-Gaa-1742 | Gasterosteus aculeatus | 47.65 | 0.0 | 1013 |
| LLPS-Scm-3387 | Scophthalmus maximus | 47.61 | 0.0 | 1003 |
| LLPS-Pof-2081 | Poecilia formosa | 47.18 | 0.0 | 1006 |
| LLPS-Xim-0993 | Xiphophorus maculatus | 47.18 | 0.0 | 1009 |
| LLPS-Rhb-4549 | Rhinopithecus bieti | 47.14 | 0.0 | 1004 |
| LLPS-Tar-3622 | Takifugu rubripes | 40.16 | 2e-67 | 254 |
| LLPS-Chr-1569 | Chlamydomonas reinhardtii | 33.71 | 2e-44 | 180 |