LLPS-Caf-3072
NRG1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Neuregulin 1 |
| Gene Name: | NRG1 |
| Ensembl Gene: | ENSCAFG00000006371.4 |
| Ensembl Protein: | ENSCAFP00000009552.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000010302.3 | ENSCAFP00000009552.3 |
| Ensembl | ENSCAFT00000010293.4 | ENSCAFP00000009544.3 |
| Ensembl | ENSCAFT00000010294.4 | ENSCAFP00000009545.3 |
| UniProt | F1Q0Y7, F1Q0Y7_CANLF | |
| GeneBank | AAEX03010413, AAEX03010412, AAEX03010414 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSERKEGRGK GKGKKERGSG KKPAPPEGGQ SPALPPRLKE MRSQESAAGS KLVLRCETSS 60 61 EYSSLKFKWF KNGNELNRKN KPQNIKIQKK PGKSELRISK ASLADSGEYM CKVTSKLGND 120 121 SASANITIVD SNDIITGMPA STERAYVSSE SPIRISVSTE GANTSSSTST STTGTSHLVK 180 181 CAEKEKTFCV NGGECFMVKD LSNPSRYLCK CQPGFTGARC TENVPMKVQN QEKAEELYQK 240 241 RVLTITGICI ALLVVGIMCV VAYCKTKKQR KKLHDRLRQS LRSERNNMVN IANGPHHPNP 300 301 PPENVQLVNQ YVSKNVISSE HIVEREAETS FSTSHYTSTA HHSTTVTQTP SHSWSNGHTE 360 361 SIISESHSVI MMSSVENSRH SSPSGGPRGR LNGLGGPREC NSFLRHARET PDSYRDSPHS 420 421 ERYVSAMTTP ARMSPVDFHT PSSPKSPPSE TSPPVSSTTV SMPSMAVSPF VEEERPLLLV 480 481 TPPRLREKYD HHSQQFNSYH HNPAHESNSL PPSPLRIVED EEYETTQEYE PAQEPVKKLT 540 541 SSRRAKRTKP NGHIANRLEM DSNASAEGTN SESETEDERV GEDTPFLGIQ NPLAASLEAA 600 601 PAFRLADSRT NPAGRFSTQE ELQARLSSVI ANQDPIAV 638 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCCGAGC GCAAAGAAGG CAGAGGCAAG GGGAAGGGCA AGAAGGAGCG CGGCTCCGGC 60 61 AAGAAGCCCG CGCCCCCGGA GGGCGGCCAG AGCCCAGCTT TGCCTCCCCG ATTGAAAGAG 120 121 ATGAGAAGCC AGGAGTCTGC TGCAGGCTCT AAACTAGTGC TTCGGTGTGA GACCAGTTCT 180 181 GAATACTCTT CTCTCAAATT CAAATGGTTC AAGAACGGGA ATGAATTAAA CCGAAAGAAC 240 241 AAACCACAAA ACATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAGCAAA 300 301 GCATCACTGG CTGATTCTGG AGAATATATG TGCAAAGTGA CCAGCAAATT AGGAAATGAC 360 361 AGTGCCTCTG CCAATATCAC CATCGTGGAT TCAAATGACA TCATCACTGG CATGCCAGCC 420 421 TCAACTGAAA GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCAACAGAA 480 481 GGAGCAAATA CTTCTTCATC TACATCTACA TCTACAACCG GAACAAGCCA TCTTGTAAAA 540 541 TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGCG AGTGCTTCAT GGTGAAAGAC 600 601 CTTTCAAACC CCTCAAGATA CTTGTGCAAG TGCCAACCTG GATTCACTGG AGCAAGATGT 660 661 ACTGAGAATG TGCCCATGAA AGTCCAAAAC CAAGAAAAAG CGGAGGAGCT CTACCAGAAG 720 721 AGAGTGCTGA CCATCACTGG CATCTGCATC GCCCTGCTTG TGGTCGGCAT CATGTGTGTG 780 781 GTGGCCTACT GCAAAACCAA GAAACAACGG AAAAAGCTTC ATGACCGGCT TCGGCAGAGT 840 841 CTTCGGTCTG AACGCAACAA CATGGTGAAC ATAGCAAACG GGCCTCACCA CCCCAACCCG 900 901 CCCCCCGAGA ACGTCCAGCT GGTGAATCAA TATGTATCTA AAAATGTCAT CTCTAGTGAA 960 961 CATATTGTTG AGAGAGAAGC GGAAACATCT TTTTCCACCA GTCACTATAC CTCAACAGCT 1020 1021 CACCACTCCA CCACCGTCAC CCAGACTCCT AGTCACAGCT GGAGCAATGG GCACACAGAA 1080 1081 AGCATCATTT CGGAAAGCCA CTCTGTAATC ATGATGTCAT CAGTAGAAAA CAGTAGGCAC 1140 1141 AGCAGCCCCT CTGGGGGCCC AAGAGGACGA CTCAATGGCT TGGGAGGCCC TCGCGAATGT 1200 1201 AACAGCTTCC TCAGGCATGC CAGAGAAACC CCTGACTCCT ACCGAGACTC TCCTCATAGT 1260 1261 GAAAGGTATG TGTCAGCAAT GACCACCCCG GCTCGTATGT CACCTGTAGA TTTCCACACG 1320 1321 CCAAGCTCCC CCAAATCTCC CCCTTCGGAA ACGTCTCCAC CTGTGTCCAG CACGACGGTG 1380 1381 TCCATGCCCT CCATGGCAGT CAGCCCCTTT GTGGAAGAAG AGAGACCTCT GCTTCTTGTG 1440 1441 ACTCCACCAC GGCTGCGGGA GAAGTATGAC CACCACTCTC AACAGTTCAA CTCCTACCAC 1500 1501 CATAACCCCG CACATGAGAG CAACAGCCTG CCCCCTAGCC CCTTGAGGAT AGTGGAGGAT 1560 1561 GAGGAGTATG AAACCACCCA GGAGTACGAG CCAGCTCAAG AGCCTGTTAA GAAACTCACC 1620 1621 AGTAGCCGGA GGGCCAAAAG AACCAAGCCC AATGGCCACA TTGCCAACAG GTTGGAAATG 1680 1681 GACAGCAACG CAAGTGCTGA GGGCACTAAC TCAGAGAGCG AAACAGAAGA TGAGAGAGTA 1740 1741 GGGGAAGATA CACCCTTCCT GGGCATTCAG AACCCCCTGG CGGCCAGTCT GGAGGCAGCA 1800 1801 CCTGCCTTCC GCCTGGCGGA CAGCAGGACT AACCCAGCAG GCCGCTTCTC GACGCAGGAA 1860 1861 GAATTGCAGG CCAGGCTGTC TAGTGTAATC GCTAACCAAG ACCCTATCGC TGTATAA 1917 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-2334 | Ursus maritimus | 98.48 | 0.0 | 681 |
| LLPS-Aim-0085 | Ailuropoda melanoleuca | 94.0 | 0.0 | 631 |
| LLPS-Fec-4587 | Felis catus | 93.36 | 0.0 | 616 |
| LLPS-Eqc-4057 | Equus caballus | 93.15 | 0.0 | 594 |
| LLPS-Ere-0111 | Erinaceus europaeus | 92.46 | 0.0 | 840 |
| LLPS-Myl-3009 | Myotis lucifugus | 92.31 | 0.0 | 585 |
| LLPS-Orc-2817 | Oryctolagus cuniculus | 92.14 | 0.0 | 572 |
| LLPS-Sus-4674 | Sus scrofa | 91.86 | 0.0 | 578 |
| LLPS-Bot-3712 | Bos taurus | 90.83 | 0.0 | 594 |
| LLPS-Chs-2594 | Chlorocebus sabaeus | 90.66 | 0.0 | 563 |
| LLPS-Rhb-2710 | Rhinopithecus bieti | 90.54 | 0.0 | 785 |
| LLPS-Maf-2567 | Macaca fascicularis | 90.38 | 0.0 | 793 |
| LLPS-Cea-3791 | Cercocebus atys | 90.38 | 0.0 | 793 |
| LLPS-Paa-0189 | Papio anubis | 90.38 | 0.0 | 793 |
| LLPS-Mal-3712 | Mandrillus leucophaeus | 90.38 | 0.0 | 793 |
| LLPS-Mam-3760 | Macaca mulatta | 90.38 | 0.0 | 793 |
| LLPS-Gog-2897 | Gorilla gorilla | 90.05 | 0.0 | 778 |
| LLPS-Pat-0516 | Pan troglodytes | 90.05 | 0.0 | 778 |
| LLPS-Hos-0339 | Homo sapiens | 89.89 | 0.0 | 778 |
| LLPS-Nol-1447 | Nomascus leucogenys | 89.89 | 0.0 | 780 |
| LLPS-Ova-2978 | Ovis aries | 89.79 | 0.0 | 578 |
| LLPS-Man-4493 | Macaca nemestrina | 89.73 | 0.0 | 804 |
| LLPS-Aon-1274 | Aotus nancymaae | 89.72 | 0.0 | 766 |
| LLPS-Poa-2287 | Pongo abelii | 89.63 | 0.0 | 571 |
| LLPS-Caj-0723 | Callithrix jacchus | 89.56 | 0.0 | 761 |
| LLPS-Fud-3262 | Fukomys damarensis | 89.51 | 0.0 | 579 |
| LLPS-Pap-2279 | Pan paniscus | 89.41 | 0.0 | 789 |
| LLPS-Mea-2919 | Mesocricetus auratus | 89.4 | 5e-164 | 492 |
| LLPS-Ict-1034 | Ictidomys tridecemlineatus | 89.32 | 0.0 | 582 |
| LLPS-Dio-2767 | Dipodomys ordii | 89.1 | 0.0 | 567 |
| LLPS-Cap-4551 | Cavia porcellus | 88.91 | 0.0 | 576 |
| LLPS-Loa-0140 | Loxodonta africana | 88.89 | 0.0 | 573 |
| LLPS-Mup-2254 | Mustela putorius furo | 88.42 | 0.0 | 785 |
| LLPS-Mum-4748 | Mus musculus | 88.25 | 0.0 | 570 |
| LLPS-Ran-3802 | Rattus norvegicus | 86.97 | 0.0 | 553 |
| LLPS-Ora-1163 | Ornithorhynchus anatinus | 81.29 | 0.0 | 681 |
| LLPS-Mod-2679 | Monodelphis domestica | 80.41 | 0.0 | 711 |
| LLPS-Sah-3161 | Sarcophilus harrisii | 80.21 | 9e-180 | 535 |
| LLPS-Gaga-1912 | Gallus gallus | 79.91 | 4e-161 | 486 |
| LLPS-Lac-1504 | Latimeria chalumnae | 79.61 | 3e-136 | 412 |
| LLPS-Tag-0007 | Taeniopygia guttata | 78.37 | 2e-169 | 507 |
| LLPS-Fia-0629 | Ficedula albicollis | 78.16 | 1e-168 | 505 |
| LLPS-Pes-2410 | Pelodiscus sinensis | 77.45 | 0.0 | 565 |
| LLPS-Anp-1843 | Anas platyrhynchos | 76.77 | 8e-157 | 467 |
| LLPS-Xet-1382 | Xenopus tropicalis | 76.63 | 2e-153 | 466 |
| LLPS-Anc-1812 | Anolis carolinensis | 72.93 | 0.0 | 592 |
| LLPS-Asm-2916 | Astyanax mexicanus | 56.67 | 6e-68 | 241 |
| LLPS-Leo-2997 | Lepisosteus oculatus | 54.55 | 1e-127 | 402 |
| LLPS-Dar-3084 | Danio rerio | 44.75 | 6e-91 | 304 |
| LLPS-Icp-2917 | Ictalurus punctatus | 41.57 | 2e-93 | 306 |
| LLPS-Gaa-3249 | Gasterosteus aculeatus | 36.99 | 3e-50 | 191 |
| LLPS-Tar-1393 | Takifugu rubripes | 36.31 | 1e-69 | 243 |
| LLPS-Orl-0293 | Oryzias latipes | 35.63 | 2e-50 | 191 |
| LLPS-Scm-3912 | Scophthalmus maximus | 35.45 | 3e-49 | 187 |
| LLPS-Xim-0491 | Xiphophorus maculatus | 35.32 | 6e-52 | 195 |
| LLPS-Ten-1866 | Tetraodon nigroviridis | 35.25 | 8e-50 | 189 |
| LLPS-Orn-3936 | Oreochromis niloticus | 35.2 | 7e-51 | 192 |
| LLPS-Pof-0943 | Poecilia formosa | 34.31 | 8e-47 | 178 |