• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-2128
CENPU

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Centromere protein U
Gene Name: CENPU
Ensembl Gene: ENSCAFG00000007735.3
Ensembl Protein: ENSCAFP00000011465.3
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSCAFT00000012373.3ENSCAFP00000011465.3
UniProtF1Q0R8, F1Q0R8_CANLF
GeneBankAAEX03010504

▼ SEQUENCE

Protein Sequence (FASTA)
1     SETSAARGGG  RKSPANADGS  GTKHQRLFVS  VRSSENTVRR  THATKDKTGP  KQKPTDVFDF  60
61    PDNSGVFSIN  RLGENEKDDE  PYDVFDPPLH  STAIYADEEE  FSRHCGSSSP  LNPQGKEAKK  120
121   RSHTYEVEEG  ENVSIEVSAK  KPRRKAKPIS  DESESTEEAV  IRRKVKPAEK  IRTRQQEPVP  180
181   DAPCRPSELP  EEPAESVTPE  NIGPLSAKSV  VEKGTDPSQL  KTQKKEIFCG  KRKKSRSKAV  240
241   DSDISDCVHI  WCLKGKKASD  ITELDVVLSA  FEKTILEYEQ  NVESKTCKEA  IKEFHSDVKE  300
301   ELLKMLKEFQ  MSKTLKRNNM  KVISDIEKKR  QHLLELQNEL  LRLEPQMKQL  QIKHDELTER  360
361   KSSLRDAAGF  LSNLKQLHQD  YSAIREKEPH  VKETYDSSSL  PALLVTARAL  LGAENHLQNI  420
421   NHRLEKLLDQ  KGDPTTKL  438
Nucleotide CDS Sequence (FASTA)
1     TCGGAAACCA  GCGCGGCCCG  CGGGGGTGGG  AGGAAAAGCC  CGGCAAATGC  AGACGGCTCA  60
61    GGGACCAAAC  ATCAGCGGCT  GTTTGTAAGT  GTGAGATCTT  CAGAGAACAC  TGTAAGAAGA  120
121   ACACATGCCA  CAAAAGATAA  AACTGGCCCA  AAACAGAAAC  CCACTGATGT  GTTTGATTTT  180
181   CCGGATAATT  CTGGTGTCTT  CAGCATCAAC  AGGCTGGGTG  AAAACGAGAA  GGATGACGAA  240
241   CCTTATGACG  TCTTTGATCC  TCCTTTACAC  AGCACTGCTA  TCTACGCTGA  TGAAGAAGAA  300
301   TTCTCCAGAC  ACTGCGGGTC  ATCCAGCCCT  TTGAATCCTC  AAGGAAAAGA  AGCAAAGAAA  360
361   AGGTCCCACA  CTTACGAAGT  GGAAGAAGGT  GAAAACGTGT  CTATAGAAGT  GAGTGCAAAA  420
421   AAGCCAAGAA  GAAAAGCCAA  GCCCATTAGC  GATGAATCTG  AAAGCACCGA  AGAAGCTGTC  480
481   ATAAGAAGGA  AAGTTAAACC  AGCAGAGAAA  ATAAGGACCC  GACAACAGGA  ACCTGTTCCA  540
541   GATGCACCGT  GTAGGCCTTC  AGAGCTTCCA  GAGGAACCAG  CCGAGTCGGT  CACTCCTGAA  600
601   AACATAGGAC  CCCTGAGCGC  CAAGTCCGTT  GTTGAAAAAG  GGACAGATCC  GAGTCAGTTG  660
661   AAAACTCAGA  AAAAGGAGAT  ATTTTGTGGC  AAAAGGAAGA  AATCAAGAAG  TAAAGCCGTA  720
721   GACTCAGATA  TTTCCGACTG  TGTACATATT  TGGTGTCTGA  AAGGAAAGAA  AGCCAGTGAC  780
781   ATCACAGAAT  TAGATGTTGT  TTTGTCTGCA  TTTGAGAAAA  CCATCCTAGA  GTATGAGCAA  840
841   AATGTAGAAT  CTAAAACTTG  TAAGGAAGCC  ATCAAAGAGT  TTCATTCTGA  TGTGAAAGAA  900
901   GAACTCCTCA  AAATGCTTAA  AGAATTCCAG  ATGTCAAAAA  CTCTGAAAAG  GAATAACATG  960
961   AAGGTTATTT  CCGATATTGA  GAAGAAGAGG  CAGCATCTGC  TTGAACTCCA  GAATGAACTG  1020
1021  CTTCGGTTAG  AACCACAGAT  GAAGCAACTC  CAGATAAAGC  ATGATGAACT  CACGGAGAGA  1080
1081  AAATCTTCCC  TTAGGGATGC  CGCAGGCTTC  TTATCTAACC  TGAAACAGCT  TCATCAAGAT  1140
1141  TATTCGGCTA  TTCGAGAGAA  AGAACCTCAC  GTAAAGGAAA  CGTATGATTC  ATCCAGCCTT  1200
1201  CCAGCTCTGT  TAGTGACAGC  GAGAGCCCTT  TTGGGAGCTG  AAAACCACCT  GCAAAATATC  1260
1261  AACCATCGAT  TAGAGAAGCT  CCTTGACCAG  AAAGGAGACC  CAACTACTAA  GCTGTGA  1317

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-2111Ailuropoda melanoleuca75.060.0 582
LLPS-Fec-2809Felis catus74.570.0 577
LLPS-Urm-0091Ursus maritimus72.570.0 554
LLPS-Mup-0663Mustela putorius furo72.40.0 588
LLPS-Eqc-4083Equus caballus71.593e-146 431
LLPS-Tut-0171Tursiops truncatus71.220.0 523
LLPS-Sus-1984Sus scrofa68.667e-165 478
LLPS-Fud-0582Fukomys damarensis66.152e-151 442
LLPS-Nol-4026Nomascus leucogenys66.02e-163 474
LLPS-Gog-3746Gorilla gorilla65.514e-163 474
LLPS-Hos-0299Homo sapiens65.261e-162 472
LLPS-Pap-2573Pan paniscus65.263e-162 471
LLPS-Poa-2497Pongo abelii65.013e-161 469
LLPS-Ova-2286Ovis aries64.881e-160 467
LLPS-Pat-1479Pan troglodytes64.765e-160 466
LLPS-Bot-0891Bos taurus64.767e-161 468
LLPS-Ict-2750Ictidomys tridecemlineatus64.628e-159 462
LLPS-Rhb-0841Rhinopithecus bieti64.271e-158 462
LLPS-Maf-0489Macaca fascicularis64.272e-157 459
LLPS-Paa-1817Papio anubis64.116e-157 458
LLPS-Loa-1030Loxodonta africana64.042e-146 430
LLPS-Mam-0639Macaca mulatta64.026e-157 458
LLPS-Mal-1193Mandrillus leucophaeus64.027e-151 442
LLPS-Cea-2912Cercocebus atys64.028e-158 460
LLPS-Chs-3453Chlorocebus sabaeus64.024e-155 453
LLPS-Aon-1753Aotus nancymaae61.791e-149 439
LLPS-Cap-3699Cavia porcellus61.431e-148 436
LLPS-Caj-1926Callithrix jacchus61.313e-146 430
LLPS-Cas-1440Carlito syrichta60.846e-146 429
LLPS-Dio-3709Dipodomys ordii60.578e-59 200
LLPS-Myl-3016Myotis lucifugus60.361e-134 399
LLPS-Man-2167Macaca nemestrina60.268e-135 401
LLPS-Orc-1062Oryctolagus cuniculus59.551e-133 398
LLPS-Ran-4737Rattus norvegicus53.382e-97 305
LLPS-Mum-2799Mus musculus52.362e-105 326
LLPS-Mea-1772Mesocricetus auratus50.812e-74 242
LLPS-Anp-1130Anas platyrhynchos48.911e-42 159
LLPS-Meg-0391Meleagris gallopavo48.41e-42 159
LLPS-Gaga-0007Gallus gallus47.065e-41 154
LLPS-Lac-2089Latimeria chalumnae44.178e-40 150
LLPS-Fia-2689Ficedula albicollis43.721e-34 137
LLPS-Tag-0656Taeniopygia guttata41.076e-35 137
LLPS-Scm-1585Scophthalmus maximus40.946e-23 104
LLPS-Xet-0947Xenopus tropicalis39.672e-30 127
LLPS-Ten-1862Tetraodon nigroviridis39.294e-1680.9
LLPS-Xim-2488Xiphophorus maculatus38.892e-1479.0
LLPS-Leo-1016Lepisosteus oculatus37.933e-22 102
LLPS-Scf-1714Scleropages formosus37.52e-25 111
LLPS-Mod-0043Monodelphis domestica37.36e-57 199
LLPS-Sah-2282Sarcophilus harrisii37.114e-1063.5
LLPS-Tar-1579Takifugu rubripes35.125e-1271.6
LLPS-Pof-1519Poecilia formosa34.95e-1477.8
LLPS-Anc-0767Anolis carolinensis34.259e-1887.4
LLPS-Dar-2212Danio rerio34.138e-2197.4
LLPS-Orl-0834Oryzias latipes33.667e-1889.4
LLPS-Icp-2839Ictalurus punctatus33.537e-1889.4