• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-1952
PRKCI

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein kinase C
Gene Name: PRKCI
Ensembl Gene: ENSCAFG00000014823.3
Ensembl Protein: ENSCAFP00000021856.3
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSCAFT00000023541.3ENSCAFP00000021856.3
UniProtF1PG28, F1PG28_CANLF
GeneBankAAEX03017373

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLGWSRPPSP  GMCAFGAGEV  GGPGGEACWA  RREEPRGSGC  PGQAPLGSGG  PRRWPSGRPC  60
61    GRPSGRPSGR  PSGRLCSGAR  PPPPPPPPAP  GAPPAASASA  LGRGSREMPT  QRDSSAMSHA  120
121   IAGGGSGDHS  HQVRVKAYYR  GDIMITHFEP  SISFEGLCNE  VRDMCSFDNE  QLFTMKWIDE  180
181   EGDPCTVSSQ  LELEEAFRLY  ELNKDSELLI  HVFPCVPERP  GMPCPGEDKS  IYRRGARRWR  240
241   KLYCANGHTF  QAKRFNRRAH  CAICTDRIWG  LGRQGYKCIN  CKLLVHKKCH  KLVTIECGRH  300
301   SMPPEPMMPM  DQSPMPSDHV  QTVIPYNPSS  HESLDQVGEE  KEAMNTRESG  KASSSLGLQD  360
361   FDLLRVIGRG  SYAKVLLVRL  KKTDRIYAMK  VVKKELVNDD  EDIDWVQTEK  HVFEQASNHP  420
421   FLVGLHSCFQ  TESRLFFVIE  YVNGGDLMFH  MQRQRKLPEE  HARFYSAEIS  LALNYLHERG  480
481   IIYRDLKLDN  VLLDSEGHIK  LTDYGMCKEG  LRPGDTTSTF  CGTPNYIAPE  ILRGEDYGFS  540
541   VDWWALGVLM  FEMMAGRSPF  DIVGSSDNPD  QNTEDYLFQV  ILEKQIRIPR  SLSVKAASVL  600
601   KSFLNKDPKE  RLGCHPQTGF  ADIQGHPFFR  NVDWDMMEQK  QVVPPFKPNI  SGEFGLDNFD  660
661   SQFTNEPVQL  TPDDDDIVRK  IDQSEFEGFE  YINPLLMSAE  ECV  703
Nucleotide CDS Sequence (FASTA)
1     ATGCTCGGAT  GGTCGCGCCC  GCCCTCCCCC  GGAATGTGCG  CCTTTGGAGC  GGGCGAGGTG  60
61    GGAGGGCCCG  GAGGGGAGGC  GTGCTGGGCC  CGGCGGGAGG  AGCCGCGCGG  TTCCGGCTGC  120
121   CCCGGCCAGG  CGCCCCTCGG  GTCGGGCGGA  CCGCGCAGGT  GGCCGAGCGG  GAGGCCGTGC  180
181   GGGAGGCCGA  GCGGGAGGCC  GAGCGGGAGG  CCGAGCGGGA  GACTCTGCAG  CGGAGCGCGC  240
241   CCGCCCCCGC  CCCCGCCGCC  CCCGGCGCCC  GGCGCGCCCC  CCGCAGCCTC  GGCCTCCGCG  300
301   CTGGGGCGGG  GGAGCAGGGA  GATGCCGACC  CAGAGGGACA  GCAGTGCCAT  GTCTCACGCG  360
361   ATCGCGGGCG  GTGGCAGCGG  GGACCATTCC  CACCAGGTCC  GGGTGAAAGC  CTACTACCGC  420
421   GGGGATATCA  TGATAACACA  TTTTGAACCT  TCAATCTCCT  TTGAGGGCCT  TTGCAATGAA  480
481   GTTCGAGATA  TGTGTTCTTT  TGACAACGAA  CAGCTTTTCA  CCATGAAATG  GATAGATGAG  540
541   GAAGGAGACC  CGTGTACAGT  ATCATCTCAG  TTGGAGTTAG  AAGAAGCCTT  TAGGCTTTAT  600
601   GAGCTGAATA  AGGATTCTGA  ACTCTTAATT  CATGTCTTCC  CTTGTGTACC  AGAACGTCCT  660
661   GGAATGCCCT  GTCCAGGAGA  AGACAAATCC  ATCTACCGCA  GAGGCGCACG  CCGATGGAGA  720
721   AAGCTTTATT  GTGCAAATGG  CCACACTTTT  CAAGCCAAGC  GTTTCAACAG  GCGTGCCCAC  780
781   TGTGCCATCT  GTACCGACCG  AATATGGGGA  CTTGGACGTC  AGGGATATAA  ATGCATCAAC  840
841   TGCAAACTCC  TGGTTCATAA  GAAGTGCCAC  AAACTCGTCA  CAATCGAATG  TGGGCGGCAT  900
901   TCTATGCCAC  CGGAACCAAT  GATGCCTATG  GACCAGTCAC  CCATGCCTTC  AGATCATGTA  960
961   CAGACAGTAA  TTCCATATAA  TCCTTCAAGT  CATGAGAGTT  TGGACCAAGT  TGGTGAAGAA  1020
1021  AAGGAGGCAA  TGAATACCAG  GGAAAGTGGC  AAAGCTTCAT  CCAGTTTAGG  TCTTCAGGAT  1080
1081  TTTGATTTGC  TTCGGGTAAT  AGGCAGAGGA  AGTTATGCCA  AAGTTCTGTT  GGTGCGATTA  1140
1141  AAAAAAACAG  ATCGTATTTA  TGCAATGAAA  GTTGTGAAAA  AAGAGCTGGT  CAATGATGAT  1200
1201  GAGGATATTG  ATTGGGTCCA  GACAGAGAAA  CATGTTTTCG  AGCAGGCATC  CAATCATCCT  1260
1261  TTTCTTGTTG  GGCTGCATTC  TTGCTTTCAG  ACAGAAAGCA  GATTGTTCTT  TGTCATAGAG  1320
1321  TATGTAAATG  GAGGAGATCT  AATGTTTCAT  ATGCAGCGAC  AAAGAAAACT  TCCTGAAGAA  1380
1381  CATGCCAGAT  TTTACTCTGC  AGAAATCAGC  CTAGCATTAA  ATTATCTTCA  TGAACGAGGG  1440
1441  ATAATTTATA  GAGATTTGAA  ATTGGACAAT  GTATTGTTGG  ACTCAGAAGG  ACACATTAAG  1500
1501  CTCACTGACT  ACGGCATGTG  TAAGGAAGGG  TTACGGCCAG  GAGATACAAC  CAGCACTTTC  1560
1561  TGTGGAACTC  CCAATTACAT  TGCTCCTGAA  ATTTTAAGAG  GAGAAGATTA  TGGTTTCAGT  1620
1621  GTTGACTGGT  GGGCCCTTGG  AGTACTAATG  TTTGAGATGA  TGGCAGGGAG  ATCTCCATTT  1680
1681  GATATTGTTG  GAAGCTCTGA  TAACCCGGAT  CAAAACACAG  AGGATTATCT  CTTCCAAGTT  1740
1741  ATTTTGGAAA  AACAAATACG  CATACCACGT  TCTCTGTCTG  TAAAAGCTGC  AAGTGTTCTG  1800
1801  AAGAGTTTTC  TCAACAAGGA  CCCAAAGGAA  CGGCTGGGTT  GTCATCCTCA  AACAGGATTT  1860
1861  GCTGATATTC  AGGGACACCC  ATTCTTTCGA  AATGTCGATT  GGGATATGAT  GGAGCAAAAG  1920
1921  CAGGTGGTAC  CTCCCTTTAA  ACCAAATATT  TCTGGGGAAT  TTGGTTTGGA  CAACTTTGAT  1980
1981  TCTCAGTTTA  CTAATGAACC  TGTCCAGCTC  ACTCCAGATG  ACGACGACAT  TGTGAGGAAG  2040
2041  ATTGATCAGT  CTGAATTTGA  AGGTTTTGAG  TACATCAATC  CTCTTTTGAT  GTCTGCAGAA  2100
2101  GAATGTGTTT  GA  2112

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ova-3758Ovis aries99.110.01102
LLPS-Aim-3585Ailuropoda melanoleuca99.050.01006
LLPS-Chs-2937Chlorocebus sabaeus98.960.0 932
LLPS-Fec-2098Felis catus98.830.01164
LLPS-Bot-0502Bos taurus98.830.01162
LLPS-Cap-2415Cavia porcellus98.750.01097
LLPS-Man-3288Macaca nemestrina98.660.01164
LLPS-Paa-0526Papio anubis98.660.01163
LLPS-Cea-3315Cercocebus atys98.660.01164
LLPS-Caj-0049Callithrix jacchus98.660.01164
LLPS-Poa-3677Pongo abelii98.490.01159
LLPS-Nol-2741Nomascus leucogenys98.490.01163
LLPS-Hos-4064Homo sapiens98.490.01166
LLPS-Aon-3313Aotus nancymaae98.320.01160
LLPS-Mup-2932Mustela putorius furo98.30.01135
LLPS-Sus-3736Sus scrofa98.30.01137
LLPS-Loa-4469Loxodonta africana98.150.01137
LLPS-Eqc-1635Equus caballus98.130.01133
LLPS-Ran-2839Rattus norvegicus97.990.01154
LLPS-Mum-1000Mus musculus97.820.01149
LLPS-Mea-2126Mesocricetus auratus97.650.01156
LLPS-Sah-3684Sarcophilus harrisii97.170.01064
LLPS-Mam-4538Macaca mulatta96.310.01151
LLPS-Fia-3723Ficedula albicollis96.260.01053
LLPS-Pap-1632Pan paniscus95.980.01151
LLPS-Anp-2483Anas platyrhynchos95.570.01044
LLPS-Urm-2657Ursus maritimus95.550.01046
LLPS-Meg-2150Meleagris gallopavo95.390.01042
LLPS-Cas-1369Carlito syrichta93.710.01087
LLPS-Gaga-3271Gallus gallus93.660.01083
LLPS-Maf-2271Macaca fascicularis93.630.01089
LLPS-Mod-1826Monodelphis domestica93.550.01066
LLPS-Icp-1279Ictalurus punctatus93.553e-64 228
LLPS-Tag-3178Taeniopygia guttata93.340.01082
LLPS-Pes-3267Pelodiscus sinensis93.250.01075
LLPS-Rhb-4238Rhinopithecus bieti92.790.01072
LLPS-Mal-1518Mandrillus leucophaeus92.110.01101
LLPS-Gog-3786Gorilla gorilla91.950.01066
LLPS-Dio-4082Dipodomys ordii90.750.01047
LLPS-Otg-4194Otolemur garnettii89.570.01040
LLPS-Leo-3553Lepisosteus oculatus88.420.01058
LLPS-Lac-2582Latimeria chalumnae88.260.01031
LLPS-Scf-2492Scleropages formosus88.090.01019
LLPS-Dar-3753Danio rerio87.920.01044
LLPS-Gaa-4019Gasterosteus aculeatus87.420.01016
LLPS-Orn-1208Oreochromis niloticus86.180.0 998
LLPS-Pof-2836Poecilia formosa85.830.01019
LLPS-Ten-2475Tetraodon nigroviridis85.790.0 993
LLPS-Xet-2301Xenopus tropicalis85.790.01029
LLPS-Pat-4245Pan troglodytes84.730.0 949
LLPS-Orl-1151Oryzias latipes83.560.0 981
LLPS-Asm-3652Astyanax mexicanus80.370.0 903
LLPS-Fud-0783Fukomys damarensis68.030.0 745
LLPS-Ict-0681Ictidomys tridecemlineatus52.83e-116 369
LLPS-Scm-3209Scophthalmus maximus51.985e-119 381
LLPS-Ora-1217Ornithorhynchus anatinus51.573e-116 369
LLPS-Xim-4136Xiphophorus maculatus51.532e-120 385
LLPS-Drm-2395Drosophila melanogaster51.351e-120 385
LLPS-Orc-1985Oryctolagus cuniculus51.198e-122 387
LLPS-Myl-2698Myotis lucifugus51.069e-124 389
LLPS-Anc-3824Anolis carolinensis50.812e-121 387
LLPS-Tar-1559Takifugu rubripes49.864e-115 368
LLPS-Cis-0057Ciona savignyi49.153e-115 370
LLPS-Cae-0673Caenorhabditis elegans43.559e-124 393