• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-1279
NEK8

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: NEK8
Ensembl Gene: ENSCAFG00000018792.3
Ensembl Protein: ENSCAFP00000038438.1
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNLGQGELKA  SPPFQRVEAP  GMVLVLKHPH  LTHRAEKSLV  PGPPMAPGGS  TGSRSAGARC  60
61    RGIPRGLGRP  AIPPPLSSVY  AWGGGLSAPL  RLPMLNTEVV  QVAAGRTQKA  GVTRSGRLIL  120
121   WEAPPLGAGG  GALLPGAVEQ  QQPQFVSRFL  EGQSGVTIKH  VACGDLFTAC  LTDRGIIMTF  180
181   GSGSNGCLGH  GSLNDISQPT  IVEALLGYEM  VQVACGASHV  LALSTERELF  AWGRGDGGRL  240
241   GLGTRESHSC  PQQVSMPPGQ  EAQRVVCGID  SSMILTVPGR  ALACGSNRFN  KLGLDRLSLG  300
301   EEPAPNQQVE  EALSFTPLGS  APFDREPLLS  VDLGTAHSAA  VTASGDCYTF  GSNQHGQLGT  360
361   NARRVSRAPC  QVQGLQNIKI  AMVACGDAFT  VAVGAEGEVY  SWGKGARGRL  GRRDEDAGLP  420
421   RPVQLDEIHP  YTVTSVSCCH  GNTLLAVRPV  TDEPVPP  457
Nucleotide CDS Sequence (FASTA)
1     ATGAACCTGG  GGCAGGGGGA  GCTCAAGGCA  AGTCCTCCAT  TTCAGCGTGT  GGAAGCACCA  60
61    GGAATGGTCC  TTGTCCTAAA  GCACCCCCAT  CTGACCCACA  GGGCAGAGAA  GTCTCTGGTC  120
121   CCCGGGCCAC  CCATGGCCCC  CGGCGGCAGC  ACAGGGAGCA  GGAGCGCCGG  CGCCCGCTGC  180
181   AGGGGCATTC  CCCGGGGACT  CGGCCGGCCG  GCCATTCCGC  CACCGCTGTC  GTCGGTTTAC  240
241   GCGTGGGGTG  GCGGGCTCAG  CGCCCCTCTG  CGGCTGCCGA  TGCTCAACAC  AGAAGTGGTG  300
301   CAGGTGGCAG  CTGGACGCAC  GCAGAAGGCC  GGCGTCACGC  GCTCGGGGCG  CCTCATCCTG  360
361   TGGGAGGCCC  CGCCCCTAGG  CGCCGGAGGG  GGCGCCCTTC  TGCCCGGGGC  CGTGGAGCAG  420
421   CAGCAGCCCC  AGTTCGTCTC  CCGCTTCCTG  GAGGGCCAGT  CAGGCGTGAC  TATCAAGCAC  480
481   GTGGCCTGTG  GGGACCTCTT  CACTGCTTGC  CTGACCGACC  GAGGTATCAT  CATGACCTTT  540
541   GGCAGTGGCA  GCAATGGGTG  CCTGGGCCAT  GGAAGCCTCA  ATGACATCAG  CCAGCCCACC  600
601   ATTGTGGAGG  CCCTGCTGGG  CTATGAGATG  GTGCAGGTGG  CCTGTGGGGC  ATCTCATGTG  660
661   CTGGCCCTGT  CCACTGAGCG  AGAACTCTTT  GCCTGGGGCC  GCGGAGATGG  TGGCCGGCTG  720
721   GGACTGGGCA  CCAGGGAGTC  CCACAGCTGC  CCCCAGCAGG  TGTCCATGCC  CCCAGGACAG  780
781   GAAGCCCAGC  GGGTTGTATG  TGGCATTGAC  TCCTCCATGA  TCCTCACTGT  ACCTGGCAGA  840
841   GCCCTGGCCT  GCGGGAGTAA  CAGGTTCAAC  AAGCTGGGCC  TGGACCGCCT  CTCCCTGGGG  900
901   GAGGAGCCTG  CCCCCAACCA  GCAGGTGGAG  GAGGCCCTGA  GCTTCACACC  ACTAGGTTCT  960
961   GCACCCTTTG  ACCGGGAGCC  CCTGCTCAGC  GTGGACCTGG  GCACTGCTCA  TTCAGCTGCC  1020
1021  GTGACTGCCT  CTGGTGACTG  CTATACTTTT  GGCAGCAATC  AGCATGGGCA  GCTGGGCACT  1080
1081  AATGCCCGCC  GGGTCAGCCG  GGCACCTTGT  CAAGTCCAAG  GCCTGCAGAA  CATCAAGATA  1140
1141  GCAATGGTAG  CCTGTGGGGA  TGCCTTCACT  GTAGCCGTTG  GGGCAGAAGG  TGAAGTGTAC  1200
1201  TCATGGGGCA  AAGGGGCCCG  AGGTCGACTA  GGCAGAAGGG  ATGAGGATGC  TGGACTCCCT  1260
1261  CGGCCAGTGC  AGCTGGATGA  GATACACCCC  TACACAGTGA  CTTCTGTGTC  CTGTTGCCAT  1320
1321  GGAAACACTC  TACTAGCTGT  TCGCCCGGTT  ACAGATGAGC  CAGTTCCACC  GTGA  1374

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-0987Ursus maritimus96.230.0 608
LLPS-Mup-1701Mustela putorius furo94.810.0 706
LLPS-Tut-0799Tursiops truncatus94.180.0 701
LLPS-Fec-4143Felis catus93.870.0 722
LLPS-Rhb-0465Rhinopithecus bieti93.420.0 695
LLPS-Gog-2455Gorilla gorilla93.160.0 692
LLPS-Cea-3832Cercocebus atys92.910.0 692
LLPS-Maf-4429Macaca fascicularis92.910.0 692
LLPS-Mal-2903Mandrillus leucophaeus92.910.0 692
LLPS-Man-1169Macaca nemestrina92.910.0 692
LLPS-Pat-3879Pan troglodytes92.910.0 692
LLPS-Pap-0238Pan paniscus92.910.0 692
LLPS-Mam-4090Macaca mulatta92.910.0 692
LLPS-Poa-3537Pongo abelii92.910.0 692
LLPS-Hos-2497Homo sapiens92.660.0 690
LLPS-Otg-0987Otolemur garnettii92.660.0 690
LLPS-Paa-1833Papio anubis92.410.0 690
LLPS-Orc-1781Oryctolagus cuniculus92.150.0 690
LLPS-Aim-0556Ailuropoda melanoleuca91.780.0 688
LLPS-Eqc-0654Equus caballus91.270.0 715
LLPS-Fud-1389Fukomys damarensis91.040.0 698
LLPS-Myl-2379Myotis lucifugus90.870.0 700
LLPS-Bot-0821Bos taurus90.60.0 695
LLPS-Loa-1176Loxodonta africana90.570.0 707
LLPS-Sus-0454Sus scrofa89.880.0 687
LLPS-Nol-2184Nomascus leucogenys89.860.0 690
LLPS-Cas-2784Carlito syrichta89.860.0 698
LLPS-Chs-0209Chlorocebus sabaeus89.740.0 698
LLPS-Aon-2791Aotus nancymaae88.920.0 688
LLPS-Cap-0224Cavia porcellus88.680.0 696
LLPS-Sah-3316Sarcophilus harrisii88.145e-24 108
LLPS-Mea-2445Mesocricetus auratus87.970.0 686
LLPS-Ict-0909Ictidomys tridecemlineatus87.710.0 673
LLPS-Mum-0279Mus musculus87.50.0 685
LLPS-Ran-2214Rattus norvegicus87.260.0 677
LLPS-Dio-1806Dipodomys ordii86.070.0 560
LLPS-Caj-1427Callithrix jacchus85.930.0 695
LLPS-Fia-0798Ficedula albicollis84.764e-80 265
LLPS-Ora-1437Ornithorhynchus anatinus80.460.0 576
LLPS-Tag-0936Taeniopygia guttata76.170.0 565
LLPS-Gaga-3972Gallus gallus75.130.0 566
LLPS-Xet-1739Xenopus tropicalis70.980.0 547
LLPS-Scm-0920Scophthalmus maximus70.680.0 534
LLPS-Dar-0721Danio rerio69.531e-179 527
LLPS-Orn-0364Oreochromis niloticus69.394e-176 518
LLPS-Leo-0011Lepisosteus oculatus69.313e-180 527
LLPS-Icp-0438Ictalurus punctatus69.112e-175 516
LLPS-Asm-3010Astyanax mexicanus68.856e-177 520
LLPS-Xim-1030Xiphophorus maculatus68.683e-177 520
LLPS-Pof-1613Poecilia formosa68.51e-174 514
LLPS-Scf-1381Scleropages formosus68.371e-170 504
LLPS-Orl-1849Oryzias latipes67.542e-168 498
LLPS-Tar-2282Takifugu rubripes67.387e-169 499
LLPS-Gaa-1375Gasterosteus aculeatus67.284e-176 518
LLPS-Ten-2374Tetraodon nigroviridis65.712e-168 498
LLPS-Lac-0661Latimeria chalumnae62.662e-169 501
LLPS-Pes-1273Pelodiscus sinensis57.892e-57 204
LLPS-Cis-1851Ciona savignyi44.963e-93 295
LLPS-Anc-3994Anolis carolinensis40.01e-0654.3
LLPS-Ova-2197Ovis aries36.033e-27 120
LLPS-Anp-1044Anas platyrhynchos35.635e-27 119
LLPS-Mod-2291Monodelphis domestica35.635e-27 119
LLPS-Meg-2557Meleagris gallopavo33.339e-45 172
LLPS-Zem-2489Zea mays33.331e-1582.8
LLPS-Vir-1677Vigna radiata32.675e-22 102
LLPS-Thc-2288Theobroma cacao32.664e-28 119
LLPS-Nia-1177Nicotiana attenuata32.198e-26 112
LLPS-Art-2726Arabidopsis thaliana32.143e-0756.6
LLPS-Cae-1540Caenorhabditis elegans32.066e-27 118
LLPS-Mae-1975Manihot esculenta32.056e-1580.9
LLPS-Coc-1146Corchorus capsularis31.993e-26 114
LLPS-Via-1846Vigna angularis31.958e-26 112
LLPS-Brr-2023Brassica rapa31.955e-25 110
LLPS-Bro-2902Brassica oleracea31.952e-24 108
LLPS-Drm-2256Drosophila melanogaster31.867e-25 112
LLPS-Cus-2234Cucumis sativus31.866e-0755.8
LLPS-Arl-1629Arabidopsis lyrata31.73e-1684.7
LLPS-Prp-1112Prunus persica31.652e-26 114
LLPS-Glm-1099Glycine max31.582e-25 112
LLPS-Phv-2244Phaseolus vulgaris31.581e-25 112
LLPS-Dac-0973Daucus carota31.569e-26 112
LLPS-Hea-1521Helianthus annuus31.541e-28 121
LLPS-Met-2113Medicago truncatula31.28e-24 107
LLPS-Hov-0479Hordeum vulgare31.26e-24 107
LLPS-Lep-1041Leersia perrieri31.163e-27 116
LLPS-Pot-1563Populus trichocarpa31.167e-28 118
LLPS-Orp-1921Oryza punctata31.013e-25 110
LLPS-Brd-1375Brachypodium distachyon30.918e-1374.3
LLPS-Tra-2082Triticum aestivum30.831e-22 103
LLPS-Gor-0345Gossypium raimondii30.834e-24 107
LLPS-Brn-3408Brassica napus30.821e-21 100
LLPS-Orb-0597Oryza barthii30.624e-27 116
LLPS-Ori-1213Oryza indica30.625e-27 116
LLPS-Orni-2312Oryza nivara30.624e-27 116
LLPS-Orgl-1973Oryza glumaepatula30.624e-27 116
LLPS-Ors-0355Oryza sativa30.625e-27 116
LLPS-Orbr-2335Oryza brachyantha30.622e-24 108
LLPS-Orr-1091Oryza rufipogon30.625e-27 116
LLPS-Org-1310Oryza glaberrima30.624e-27 116
LLPS-Viv-0380Vitis vinifera30.232e-26 114
LLPS-Sob-2022Sorghum bicolor30.231e-25 112
LLPS-Orm-1818Oryza meridionalis30.222e-22 103
LLPS-Mua-2482Musa acuminata30.15e-25 110
LLPS-Sei-0110Setaria italica29.51e-21 100