LLPS-Caf-1221
NPHS1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | NPHS1, nephrin |
| Gene Name: | NPHS1 |
| Ensembl Gene: | ENSCAFG00000006758.3 |
| Ensembl Protein: | ENSCAFP00000010092.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Scaffold |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet, Others | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000010890.3 | ENSCAFP00000010092.3 |
| UniProt | F1PJZ9, F1PJZ9_CANLF | |
| GeneBank | AAEX03001005 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MALRTPSRAP LLLMGLLTTG LAQLPLSASA PRGFWALPEN LTVVEGATAE LQCGVHAPGS 60 61 VVQWAKDGLL LGPDPRIPRF PRYRLEGDPS RGEFHLHIEA CDLSDDAEYE CQVGRSETGP 120 121 ELVSPRVILS VLVPPKVLQL TPEAGSTVTW VAGQEYVVTC VSGDAKPAPD ITFFQSGQTV 180 181 SDISANVNAG SQEKLFTTEA TARVTPQSSD NGQLLVCEGS SPALDTPIRV SVTMNVLFPP 240 241 GPPVIEWPGL DEGHVRAGQS LELLCVARGG NPPATLQWLK NGQPMSTAWG TEHAEAVARS 300 301 MLVMVVRPED HGARLSCEAH NSVSTGIQER GVTLQVTFPP SAITILGSAS QSENKNVTLS 360 361 CISKSSRPRV LLRWWLGWRQ LVPTEEMVVD GLHGGHISMS NLTFLVRRED NGLTLTCEAF 420 421 SEAFTKETFK KSLTLNVKYP AQKLWIEGPP EGQRLRAGTR VRLVCLAIGG NPEPSLTWLK 480 481 DSRTVTEPRP PQEPRRVQLG SLEKSGSTFS RELILITGPS DNQAKFTCKA GQLSASTQLV 540 541 VQFPPTNVTI LANATALRPG DALNLTCISV SSNPPVNLSW DKEGERLESV ATPPRSAPFK 600 601 GSAAARSVLL RMSSRDHGHR VTCQAHSPEL RETMSAFYRL NVLYPPEFLG EQVLVVTAVE 660 661 QGEALLPVSV SANPAPEAFN WTFRGYRLSP AGGPRHRILS GGALQLWNVT RADDGLYQLH 720 721 CQNSEGTAET LVRLDVHYAP TIRALQDPTE VNIGGSVDIV CTVDANPILP EMFSWERLGE 780 781 EEEDQSLDDM EKISKGSTGR LRIHHAKLAQ AGAYQCIVDN GVAPPARGLV RLVVRFAPQV 840 841 EHPTPLNKVA AAGDSTSSAT LHCRARGVPN IVFTWAKNGV PLDLEDPRYT EHTYHQGGVH 900 901 SSLLTIANVS AAQDYALFTC TATNPLGSDH TNIQLVSISR PDPPTGLKVV SMTPYSVGLE 960 961 WKPGFDGGLP QKFQIRYEAL GTPGFLYMDV LPPDATTFTL TGLQPSTRYR VWLLASNALG 1020 1021 DSGLTDKGSQ IPITTPGLDE PSGEPDYQLP TEQPVGPSGL PLLPVLFAVG GLLLLSNISC 1080 1081 VGGFLWQRRL RRLAEGISEK TETGSEEDRV RNEYEDSRWT GDQDTRSSTV STTDVEPYYH 1140 1141 SMKNFSPQLP PTLEEMSYLR GFTHIEEENM AFPGHLYDEV ERLYAPPGAW GPIYDEVPMG 1200 1201 PSDPSWPEET YEDTRRIYDR VAGNLDPVET DSLPFELRGH LV 1242 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCCTGA GGACCCCCAG CAGGGCTCCC CTGCTCCTCA TGGGGCTGCT GACCACAGGC 60 61 CTGGCCCAGT TGCCGCTCTC TGCCTCGGCC CCTCGAGGCT TCTGGGCTCT GCCAGAAAAC 120 121 TTGACGGTGG TGGAGGGAGC CACTGCTGAG CTGCAGTGTG GGGTCCACGC CCCTGGCAGT 180 181 GTGGTACAAT GGGCCAAAGA TGGGCTACTC CTGGGCCCTG ATCCTAGGAT CCCCCGCTTC 240 241 CCGAGGTACC GCCTGGAAGG AGACCCGAGT AGAGGTGAAT TCCACCTGCA TATTGAAGCG 300 301 TGTGACCTGA GCGACGATGC AGAGTATGAG TGTCAGGTCG GCCGCTCGGA GACAGGCCCT 360 361 GAGCTCGTGT CTCCCAGAGT GATCCTCTCC GTCCTGGTGC CCCCCAAAGT GCTTCAGCTG 420 421 ACCCCTGAGG CAGGGAGCAC AGTCACGTGG GTAGCTGGGC AGGAGTACGT GGTCACCTGT 480 481 GTGTCTGGGG ACGCGAAGCC GGCACCCGAC ATCACCTTCT TCCAGAGTGG ACAAACAGTT 540 541 TCTGACATCT CTGCCAATGT GAATGCGGGG TCCCAGGAGA AACTCTTCAC CACAGAGGCC 600 601 ACAGCCAGGG TGACACCCCA GAGCTCAGAT AATGGGCAGC TATTGGTCTG TGAGGGGTCC 660 661 AGCCCAGCAT TGGACACCCC TATCCGGGTC TCGGTCACCA TGAATGTTCT GTTCCCCCCA 720 721 GGGCCCCCTG TCATTGAATG GCCAGGCCTG GACGAGGGGC ATGTGCGGGC AGGACAGAGC 780 781 TTGGAGCTGC TGTGTGTGGC CCGAGGGGGG AACCCGCCAG CCACACTGCA GTGGCTGAAG 840 841 AATGGCCAGC CCATGTCCAC AGCGTGGGGC ACAGAGCACG CTGAGGCAGT GGCCCGAAGC 900 901 ATGCTAGTGA TGGTCGTGCG ACCGGAAGAC CACGGGGCGA GGCTCAGCTG TGAGGCCCAC 960 961 AACAGCGTAT CTACAGGGAT CCAGGAGCGC GGGGTCACGC TGCAGGTCAC CTTTCCCCCT 1020 1021 AGTGCCATTA CCATCTTGGG ATCCGCATCC CAGTCTGAGA ACAAGAACGT TACGCTCTCC 1080 1081 TGCATCTCCA AGTCCAGTCG CCCACGGGTC CTGTTGCGAT GGTGGCTGGG TTGGCGGCAG 1140 1141 CTGGTGCCCA CAGAAGAGAT GGTCGTGGAT GGCCTGCATG GTGGCCACAT CTCCATGTCC 1200 1201 AATTTGACGT TCCTGGTGCG ACGGGAGGAC AATGGTCTGA CTCTCACGTG TGAGGCCTTT 1260 1261 AGTGAGGCCT TCACCAAGGA GACCTTCAAG AAATCACTCA CCCTGAATGT GAAATATCCT 1320 1321 GCCCAGAAGT TGTGGATAGA GGGTCCGCCA GAGGGACAAC GCCTCCGGGC TGGGACTCGA 1380 1381 GTGAGGCTGG TGTGTTTGGC CATTGGAGGC AACCCAGAAC CCTCTCTTAC TTGGCTCAAG 1440 1441 GACTCCCGGA CGGTGACTGA ACCGCGGCCG CCCCAGGAGC CGCGGAGGGT GCAGCTGGGA 1500 1501 AGTCTGGAGA AGTCAGGGAG CACGTTCTCC CGAGAGCTTA TACTGATCAC GGGTCCATCG 1560 1561 GACAACCAGG CCAAGTTCAC GTGCAAGGCG GGTCAGCTGA GCGCATCCAC GCAGCTTGTG 1620 1621 GTGCAGTTTC CCCCAACAAA CGTGACGATC TTGGCCAATG CTACGGCACT GCGCCCAGGG 1680 1681 GATGCATTAA ACTTGACTTG CATCAGTGTT AGCAGCAACC CGCCTGTCAA CTTGTCGTGG 1740 1741 GACAAGGAGG GGGAGAGGCT GGAAAGTGTG GCCACACCGC CCCGTAGTGC CCCATTCAAA 1800 1801 GGCTCTGCGG CAGCCAGGAG CGTCCTTCTG AGAATGTCAT CCCGAGACCA CGGCCACCGA 1860 1861 GTGACCTGCC AAGCCCACAG TCCTGAGCTA CGGGAAACCA TGAGCGCTTT CTACCGCCTC 1920 1921 AACGTGCTGT ATCCTCCAGA GTTCCTGGGG GAGCAGGTGC TTGTGGTGAC CGCGGTGGAG 1980 1981 CAGGGTGAGG CACTGCTGCC GGTGTCTGTG TCTGCCAACC CTGCCCCGGA GGCCTTCAAC 2040 2041 TGGACTTTCC GTGGCTACCG TCTCAGCCCA GCTGGCGGCC CTCGGCATCG CATCTTGTCT 2100 2101 GGTGGAGCTC TGCAGCTGTG GAATGTGACC CGTGCTGACG ATGGCCTCTA TCAGCTGCAT 2160 2161 TGCCAGAACT CAGAGGGCAC CGCCGAAACT CTAGTGCGGC TGGATGTACA CTATGCTCCC 2220 2221 ACTATCCGAG CTCTCCAGGA TCCTACTGAG GTGAATATTG GGGGTTCTGT GGACATAGTC 2280 2281 TGCACTGTTG ATGCCAATCC TATCCTTCCA GAGATGTTCA GCTGGGAGAG GCTGGGAGAA 2340 2341 GAGGAGGAGG ACCAGAGCCT GGATGACATG GAGAAGATAT CAAAAGGATC GACAGGGCGT 2400 2401 CTTCGAATTC ACCATGCCAA ACTGGCCCAG GCTGGTGCTT ACCAGTGCAT CGTGGATAAT 2460 2461 GGAGTGGCAC CTCCAGCCCG AGGGTTGGTC CGACTTGTTG TCAGATTCGC CCCCCAGGTG 2520 2521 GAGCACCCCA CTCCCCTAAA CAAGGTGGCT GCAGCTGGAG ACAGTACAAG TTCTGCCACT 2580 2581 CTCCACTGTC GTGCCCGAGG CGTCCCCAAC ATCGTCTTCA CTTGGGCCAA AAATGGAGTC 2640 2641 CCTCTGGATC TCGAGGATCC CAGGTACACA GAGCACACAT ACCACCAGGG TGGGGTCCAC 2700 2701 AGCAGTCTCC TGACCATTGC CAACGTGTCT GCAGCCCAGG ATTATGCCCT CTTCACGTGC 2760 2761 ACAGCCACCA ACCCCCTTGG CTCAGACCAC ACCAACATTC AACTCGTCAG CATTAGCCGC 2820 2821 CCGGATCCCC CAACAGGATT AAAGGTTGTA AGCATGACCC CATATTCGGT GGGGTTGGAA 2880 2881 TGGAAGCCTG GCTTTGATGG GGGTTTGCCA CAGAAGTTCC AAATCAGATA TGAGGCACTT 2940 2941 GGGACTCCAG GGTTCCTCTA CATGGACGTC CTACCGCCTG ATGCCACCAC CTTCACACTA 3000 3001 ACTGGGCTAC AGCCTTCTAC ACGATACAGG GTCTGGCTGC TAGCCAGCAA TGCCCTGGGG 3060 3061 GACAGCGGAC TAACTGACAA GGGGTCCCAG ATCCCTATTA CCACCCCAGG TCTAGACGAG 3120 3121 CCTTCTGGAG AACCTGACTA CCAGCTGCCC ACAGAGCAGC CTGTAGGACC CTCAGGGCTG 3180 3181 CCTCTACTGC CTGTGCTGTT TGCTGTTGGG GGTCTTTTGC TGCTTTCTAA TATCTCCTGT 3240 3241 GTTGGAGGAT TCCTCTGGCA GCGGAGACTG AGGCGTCTTG CTGAAGGCAT CTCGGAGAAG 3300 3301 ACAGAGACAG GGTCGGAGGA GGACCGAGTC AGGAATGAAT ATGAGGACAG CCGGTGGACT 3360 3361 GGAGACCAGG ACACTCGAAG CTCCACAGTT AGCACAACAG ATGTGGAACC ATATTACCAC 3420 3421 TCCATGAAGA ACTTCAGCCC CCAGCTGCCA CCAACACTGG AGGAGATGTC TTATCTCCGA 3480 3481 GGTTTCACAC ATATTGAAGA GGAGAATATG GCTTTTCCTG GACACCTGTA TGATGAAGTG 3540 3541 GAAAGGCTAT ATGCCCCGCC TGGGGCCTGG GGACCCATCT ATGATGAAGT ACCAATGGGC 3600 3601 CCCTCTGACC CCTCCTGGCC TGAGGAGACA TATGAGGATA CAAGAAGAAT CTATGATCGG 3660 3661 GTAGCAGGAA ACTTGGACCC TGTGGAAACT GATTCTCTAC CCTTTGAGCT GAGGGGACAT 3720 3721 CTGGTGTGA 3729 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mup-0927 | Mustela putorius furo | 94.44 | 0.0 | 2283 |
| LLPS-Urm-2314 | Ursus maritimus | 94.27 | 0.0 | 2278 |
| LLPS-Aim-1082 | Ailuropoda melanoleuca | 94.22 | 0.0 | 2297 |
| LLPS-Fec-4148 | Felis catus | 93.32 | 0.0 | 2273 |
| LLPS-Eqc-3364 | Equus caballus | 90.57 | 0.0 | 2149 |
| LLPS-Bot-2067 | Bos taurus | 89.86 | 0.0 | 2170 |
| LLPS-Sus-3133 | Sus scrofa | 89.47 | 0.0 | 2170 |
| LLPS-Ova-2650 | Ovis aries | 89.29 | 0.0 | 2146 |
| LLPS-Myl-2984 | Myotis lucifugus | 88.57 | 0.0 | 2175 |
| LLPS-Otg-3629 | Otolemur garnettii | 87.52 | 0.0 | 2160 |
| LLPS-Pat-0475 | Pan troglodytes | 87.52 | 0.0 | 2117 |
| LLPS-Aon-4619 | Aotus nancymaae | 87.38 | 0.0 | 2091 |
| LLPS-Gog-3776 | Gorilla gorilla | 87.07 | 0.0 | 2048 |
| LLPS-Hos-2735 | Homo sapiens | 87.04 | 0.0 | 2107 |
| LLPS-Loa-4593 | Loxodonta africana | 86.54 | 0.0 | 2100 |
| LLPS-Chs-1678 | Chlorocebus sabaeus | 85.85 | 0.0 | 2078 |
| LLPS-Poa-4548 | Pongo abelii | 85.77 | 0.0 | 1880 |
| LLPS-Caj-0849 | Callithrix jacchus | 85.75 | 0.0 | 2055 |
| LLPS-Orc-4256 | Oryctolagus cuniculus | 85.67 | 0.0 | 2076 |
| LLPS-Mam-4490 | Macaca mulatta | 85.2 | 0.0 | 2080 |
| LLPS-Ict-4242 | Ictidomys tridecemlineatus | 84.88 | 0.0 | 1583 |
| LLPS-Man-2225 | Macaca nemestrina | 84.8 | 0.0 | 1960 |
| LLPS-Fud-0486 | Fukomys damarensis | 84.21 | 0.0 | 2060 |
| LLPS-Paa-3974 | Papio anubis | 84.05 | 0.0 | 2021 |
| LLPS-Pap-4477 | Pan paniscus | 83.85 | 0.0 | 2041 |
| LLPS-Mea-3898 | Mesocricetus auratus | 83.29 | 0.0 | 1975 |
| LLPS-Mum-3891 | Mus musculus | 83.13 | 0.0 | 2015 |
| LLPS-Cap-0798 | Cavia porcellus | 82.77 | 0.0 | 2020 |
| LLPS-Ran-4001 | Rattus norvegicus | 82.41 | 0.0 | 1986 |
| LLPS-Cea-4775 | Cercocebus atys | 82.38 | 0.0 | 1955 |
| LLPS-Cas-0315 | Carlito syrichta | 81.9 | 0.0 | 1955 |
| LLPS-Nol-1216 | Nomascus leucogenys | 81.64 | 0.0 | 1931 |
| LLPS-Dio-0389 | Dipodomys ordii | 81.45 | 0.0 | 1961 |
| LLPS-Maf-2459 | Macaca fascicularis | 78.45 | 0.0 | 1877 |
| LLPS-Mal-2235 | Mandrillus leucophaeus | 68.14 | 0.0 | 944 |
| LLPS-Mod-3498 | Monodelphis domestica | 62.49 | 0.0 | 1498 |
| LLPS-Ora-3092 | Ornithorhynchus anatinus | 60.38 | 2e-33 | 131 |
| LLPS-Anc-0552 | Anolis carolinensis | 47.09 | 0.0 | 899 |
| LLPS-Lac-0334 | Latimeria chalumnae | 45.81 | 0.0 | 862 |
| LLPS-Xet-3866 | Xenopus tropicalis | 45.62 | 0.0 | 904 |
| LLPS-Asm-2753 | Astyanax mexicanus | 44.04 | 0.0 | 815 |
| LLPS-Leo-2267 | Lepisosteus oculatus | 43.72 | 0.0 | 943 |
| LLPS-Scf-0564 | Scleropages formosus | 43.01 | 0.0 | 806 |
| LLPS-Icp-4148 | Ictalurus punctatus | 42.86 | 0.0 | 842 |
| LLPS-Tar-2510 | Takifugu rubripes | 42.55 | 0.0 | 796 |
| LLPS-Ten-3833 | Tetraodon nigroviridis | 42.45 | 0.0 | 810 |
| LLPS-Gaa-2349 | Gasterosteus aculeatus | 41.32 | 0.0 | 756 |
| LLPS-Xim-1628 | Xiphophorus maculatus | 40.37 | 0.0 | 823 |
| LLPS-Scm-3456 | Scophthalmus maximus | 39.44 | 0.0 | 813 |
| LLPS-Pof-3532 | Poecilia formosa | 39.12 | 0.0 | 811 |
| LLPS-Orl-3436 | Oryzias latipes | 38.83 | 0.0 | 758 |
| LLPS-Dar-4049 | Danio rerio | 38.78 | 0.0 | 813 |
| LLPS-Orn-0310 | Oreochromis niloticus | 38.22 | 0.0 | 798 |
| LLPS-Drm-0753 | Drosophila melanogaster | 31.64 | 2e-145 | 485 |
| LLPS-Fia-3791 | Ficedula albicollis | 28.38 | 5e-06 | 55.5 |
| LLPS-Cii-1231 | Ciona intestinalis | 28.17 | 4e-88 | 312 |
| LLPS-Rhb-4159 | Rhinopithecus bieti | 27.46 | 1e-07 | 60.8 |
| LLPS-Tut-1930 | Tursiops truncatus | 25.5 | 2e-07 | 59.7 |
| LLPS-Cae-1217 | Caenorhabditis elegans | 24.66 | 2e-83 | 301 |
| LLPS-Sah-3863 | Sarcophilus harrisii | 24.15 | 1e-12 | 77.4 |
| LLPS-Gaga-2896 | Gallus gallus | 23.44 | 9e-08 | 61.2 |
| LLPS-Meg-3025 | Meleagris gallopavo | 23.38 | 2e-07 | 60.1 |