LLPS-Caf-0189
KDM3A
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Lysine demethylase 3A |
| Gene Name: | KDM3A |
| Ensembl Gene: | ENSCAFG00000007522.3 |
| Ensembl Protein: | ENSCAFP00000011182.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000012063.3 | ENSCAFP00000011182.3 |
| UniProt | E2QWU9, E2QWU9_CANLF | |
| GeneBank | AAEX03010929 | |
| RefSeq | XM_532973.5 | XP_532973.3 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MVLTLGESWP VLVGKRFLSL SAADGGDGGH DSWDVERVAE WPWVSGTIRA VSHTDVTKKD 60 61 LKVCVEFDGE SWRKRRWIEV YSLLRRAFLV EHNLVLAERK SPEISERVVQ WPAIVYKSLL 120 121 DKAGLGSITS IRFLGDQQRV FLSKDLLKPI QDVNNLRLSL MDNQNVSKEF QALIVKHLDE 180 181 SHLLQGDKNL VGSEVKIYSL DPSTQWFSAT IVNGNPASKT LQVNCEEIPA LKIVDPSLIH 240 241 VEVVHDNFVT CGNSTRIGTV KRKSSENNGS LVSKQAKSCS EASPSVCPVQ SVPTTVFKEI 300 301 LLGCTAATPP SKDPRQQSTP QAANSPPNLG AKIPQGCHKQ ILPEELSSCL NTKAEILRTK 360 361 PDVCKVGLLS SKFPQIGTGD LKPLSEPKDN CTQLKTNTDK ENKLESVSQS STGLPKEGVP 420 421 TKPSTAEVEI ASTPELQKHL EYAPSTSDVL SNKPEEKAGV VSNSPNSCVE KKIETSTLGC 480 481 RSQTLKESSV KIDNESCCTR SNNKIQNAPS RKSVLTDPAK LKKLQQSGEA FVQDDSCVNI 540 541 VAQLPKCREC RLDSLRKDKE QQKDSPVFCR FFHFRRLQFN KHGVLRVEGF LTPNKYDSEA 600 601 IGLWLPLTKN VVGTDLDTAK YILANIGDHF CQMVISEKEA MSTIEPHRQV AWKRAVKGVR 660 661 EMCDVCDTTI FNLHWVCPRC GFGVCVDCYR MKRKNCQQGA AYKTFSWLRC VKSQIHEPEN 720 721 LMPTQIIPGK ALYDVGDIVH SVRAKWGIKA NCPCSNRQFK LFSKPASKED VKQTSFAGEK 780 781 PSLGAVFQQN PLVLEPVPVA GEAASKPASS MKPACPASTS PLNWLADLTS GNVNKENKEK 840 841 QPTMPILKNE IKCLPPLPPL SKSSTVLHTF NSTILTPVSN NNSGFLRNLL NSSTGKTENG 900 901 LKNTPKILDD IFASLVQNKT SSDLSKRPQG LTIKPSILGF DTPHYWLCDN RLLCLQDPNN 960 961 KSNWNVFREC WKQGQPVMVS GVHHKLNTDL WKPESFRKEF GNQEVDLVNC RTNEIITGAT 1020 1021 VGDFWDGFED VPNRLKNEKE PMVLKLKDWP PGEDFRDMMP SRFDDLMANI PLPEYTRRDG 1080 1081 KLNLASRLPN YFVRPDLGPK MYNAYGLITP EDRKYGTTNL HLDVSDAANV MVYVGIPKGQ 1140 1141 CDQEEEVLKT IQDGDSDELT IKRFIEGKEK PGALWHIYAA KDTEKIREFL KKVSEEQGQE 1200 1201 NPADHDPIHD QSWYLDRSLR KRLHQEYGVQ GWAIVQFLGD VVFIPAGAPH QVHNLYSCIK 1260 1261 VAEDFVSPEH VKHCFWLTQE FRYLSQTHTN HEDKLQVKNV IYHAVKDAVA MLKASESSFG 1320 1321 KP 1322 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGTGCTCA CGCTCGGAGA AAGTTGGCCA GTATTGGTGG GGAAGCGATT CCTCAGTCTG 60 61 TCCGCAGCCG ACGGCGGCGA CGGCGGCCAC GACAGCTGGG ACGTGGAGCG CGTCGCCGAG 120 121 TGGCCCTGGG TCTCGGGGAC CATTCGAGCC GTCTCCCACA CCGACGTTAC CAAGAAGGAC 180 181 CTGAAGGTGT GTGTGGAGTT TGATGGGGAA TCTTGGAGAA AGAGAAGATG GATAGAAGTC 240 241 TATAGCCTTC TAAGGAGAGC ATTTTTAGTA GAGCATAACT TGGTTTTGGC TGAACGAAAG 300 301 TCTCCTGAAA TTTCTGAACG AGTTGTTCAG TGGCCTGCAA TAGTGTATAA GTCTCTGTTG 360 361 GACAAAGCTG GTTTGGGATC CATAACCTCT ATTCGCTTTC TGGGAGATCA ACAAAGAGTA 420 421 TTTCTTTCTA AAGACCTTCT GAAGCCTATA CAGGATGTAA ACAATCTTCG ACTTTCCCTT 480 481 ATGGATAATC AGAATGTCAG TAAAGAATTT CAAGCTTTGA TTGTGAAACA TTTGGATGAA 540 541 AGCCATCTTT TACAAGGTGA CAAAAACTTA GTTGGTTCAG AAGTAAAAAT ATATAGCTTG 600 601 GACCCATCTA CTCAGTGGTT TTCTGCAACC ATTGTAAATG GAAACCCAGC GTCGAAAACT 660 661 CTGCAGGTCA ACTGTGAGGA GATTCCAGCA CTGAAAATTG TCGATCCATC ACTGATTCAT 720 721 GTTGAAGTTG TACATGATAA CTTTGTGACA TGTGGTAATT CTACAAGAAT CGGAACTGTA 780 781 AAACGCAAGT CTTCTGAAAA TAATGGAAGC CTAGTTTCCA AACAAGCAAA ATCTTGCTCT 840 841 GAGGCCTCTC CCAGTGTGTG TCCTGTACAG TCTGTTCCCA CAACAGTTTT TAAGGAGATA 900 901 CTGCTTGGCT GTACTGCAGC AACTCCACCT AGTAAGGACC CAAGGCAGCA GAGCACTCCC 960 961 CAGGCTGCCA ACTCTCCACC TAACCTTGGA GCAAAAATTC CTCAAGGATG TCATAAACAG 1020 1021 ATTTTACCAG AAGAACTTTC TTCCTGTCTG AATACAAAGG CTGAAATACT GAGAACAAAA 1080 1081 CCAGATGTCT GCAAAGTAGG ATTGCTGTCT TCAAAGTTCC CTCAGATTGG AACAGGAGAC 1140 1141 TTAAAACCCC TTAGTGAACC AAAAGATAAC TGTACCCAGC TGAAAACCAA CACTGATAAG 1200 1201 GAAAACAAAT TGGAATCTGT TTCTCAGTCA TCAACTGGCC TTCCTAAGGA GGGCGTACCT 1260 1261 ACAAAGCCTT CTACAGCAGA AGTGGAAATT GCCAGTACAC CTGAACTACA GAAGCACCTA 1320 1321 GAGTATGCAC CTTCTACATC TGATGTCCTT TCAAATAAGC CAGAAGAGAA AGCTGGTGTT 1380 1381 GTTAGTAACA GCCCTAATAG TTGTGTGGAA AAGAAGATAG AAACTTCAAC TTTAGGATGC 1440 1441 CGGTCACAGA CTTTGAAGGA ATCTTCAGTA AAAATAGATA ATGAAAGCTG TTGTACAAGA 1500 1501 AGCAACAATA AAATCCAGAA TGCCCCCTCT CGGAAGTCGG TTTTGACAGA CCCAGCCAAA 1560 1561 CTCAAGAAGC TGCAGCAGAG TGGTGAGGCC TTTGTACAAG ATGACTCCTG TGTGAACATT 1620 1621 GTTGCACAGC TGCCCAAGTG CCGGGAGTGT CGCTTGGACA GCCTCCGCAA AGATAAGGAG 1680 1681 CAGCAGAAAG ACTCACCTGT GTTTTGTCGT TTCTTTCACT TCAGGAGGTT ACAGTTCAAC 1740 1741 AAACATGGTG TGTTGCGGGT AGAAGGCTTC TTAACACCAA ACAAGTATGA CAGTGAAGCA 1800 1801 ATTGGCTTAT GGTTGCCTTT AACTAAAAAC GTTGTGGGGA CCGATTTGGA CACTGCAAAG 1860 1861 TATATCCTGG CCAACATTGG AGACCACTTC TGTCAAATGG TGATTTCTGA AAAGGAAGCT 1920 1921 ATGTCAACTA TTGAGCCACA CAGACAGGTT GCTTGGAAGC GAGCTGTCAA AGGTGTTCGG 1980 1981 GAAATGTGTG ATGTATGTGA CACCACCATC TTCAACCTGC ACTGGGTGTG CCCTAGGTGT 2040 2041 GGGTTTGGAG TTTGTGTGGA TTGCTACCGG ATGAAGAGGA AGAATTGCCA ACAAGGTGCT 2100 2101 GCCTACAAGA CTTTCTCATG GCTAAGATGT GTGAAGAGTC AGATACATGA GCCAGAGAAC 2160 2161 CTAATGCCTA CACAGATCAT TCCTGGGAAA GCCCTCTATG ATGTTGGAGA CATTGTTCAT 2220 2221 TCTGTGAGAG CAAAATGGGG AATAAAAGCA AATTGTCCCT GTTCTAACAG GCAATTCAAA 2280 2281 CTCTTTTCAA AGCCAGCCTC AAAGGAAGAT GTAAAACAGA CTTCTTTTGC TGGAGAAAAA 2340 2341 CCTAGCCTTG GTGCTGTGTT CCAGCAGAAT CCTTTGGTGT TGGAGCCAGT GCCTGTGGCT 2400 2401 GGGGAGGCTG CTTCCAAGCC AGCCAGCAGC ATGAAGCCTG CCTGTCCAGC CAGTACATCT 2460 2461 CCCTTAAACT GGCTGGCAGA CCTAACCAGC GGGAATGTCA ACAAGGAAAA CAAAGAAAAA 2520 2521 CAACCAACAA TGCCAATTCT AAAGAATGAA ATCAAATGCC TTCCACCCCT CCCTCCTTTG 2580 2581 AGCAAATCCA GCACAGTCCT CCACACCTTT AACAGCACAA TTTTAACACC TGTAAGCAAC 2640 2641 AACAATTCTG GTTTCCTCCG AAATCTCTTG AATTCCTCTA CAGGAAAGAC AGAAAATGGA 2700 2701 CTGAAGAATA CACCAAAAAT CCTTGATGAC ATCTTTGCCT CTTTGGTGCA AAATAAGACT 2760 2761 TCCTCTGATT TATCTAAGAG GCCTCAAGGA CTGACCATTA AGCCCAGCAT TCTGGGCTTT 2820 2821 GACACTCCTC ATTACTGGCT CTGTGATAAT CGCTTGCTGT GCCTCCAGGA TCCCAACAAC 2880 2881 AAGAGCAACT GGAATGTGTT TAGGGAGTGC TGGAAACAAG GACAGCCAGT GATGGTGTCA 2940 2941 GGAGTGCATC ATAAATTGAA CACTGACCTT TGGAAACCTG AATCCTTCAG GAAAGAGTTT 3000 3001 GGGAATCAAG AAGTCGACCT AGTTAACTGT AGGACCAATG AAATCATCAC AGGAGCCACA 3060 3061 GTAGGAGACT TCTGGGATGG ATTTGAAGAT GTTCCAAACC GCTTGAAAAA TGAAAAAGAA 3120 3121 CCAATGGTGT TGAAACTTAA GGACTGGCCA CCAGGAGAGG ATTTTAGAGA TATGATGCCT 3180 3181 TCTAGGTTTG ATGATCTGAT GGCCAATATC CCATTACCTG AGTACACAAG GAGAGATGGC 3240 3241 AAACTAAACT TGGCCTCCAG GCTGCCAAAC TACTTCGTGA GGCCAGATCT CGGTCCGAAG 3300 3301 ATGTATAATG CTTACGGATT AATTACTCCA GAAGACAGGA AATATGGAAC AACAAATCTT 3360 3361 CACTTAGATG TATCTGATGC AGCTAATGTC ATGGTATATG TGGGAATTCC CAAGGGACAG 3420 3421 TGTGACCAAG AAGAAGAAGT CCTTAAAACC ATCCAAGACG GAGATTCTGA TGAACTCACA 3480 3481 ATAAAGCGAT TTATTGAAGG AAAAGAGAAG CCAGGAGCCC TCTGGCACAT ATATGCTGCG 3540 3541 AAGGACACAG AGAAAATACG AGAATTCCTT AAAAAGGTAT CAGAAGAGCA AGGTCAAGAA 3600 3601 AACCCAGCAG ACCATGATCC CATTCATGAT CAGAGCTGGT ATTTAGACCG ATCACTAAGA 3660 3661 AAGCGTCTCC ATCAAGAATA TGGAGTTCAA GGCTGGGCTA TTGTACAGTT TCTTGGGGAT 3720 3721 GTGGTATTTA TCCCAGCAGG AGCTCCACAT CAGGTGCATA ACTTATATAG CTGTATCAAA 3780 3781 GTGGCTGAAG ATTTTGTTTC TCCAGAGCAT GTTAAACACT GTTTCTGGCT TACTCAGGAA 3840 3841 TTCCGTTATC TGTCACAGAC TCATACCAAT CATGAAGATA AATTACAGGT GAAAAATGTT 3900 3901 ATCTACCATG CAGTGAAAGA TGCAGTTGCT ATGCTAAAAG CCAGTGAATC CAGTTTTGGC 3960 3961 AAACCCTAA 3969 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Dio-2939 | Dipodomys ordii | 98.16 | 4e-136 | 454 |
| LLPS-Aim-2857 | Ailuropoda melanoleuca | 97.66 | 0.0 | 2600 |
| LLPS-Urm-3879 | Ursus maritimus | 97.51 | 0.0 | 2592 |
| LLPS-Mup-0273 | Mustela putorius furo | 97.05 | 0.0 | 2580 |
| LLPS-Fec-3372 | Felis catus | 96.66 | 0.0 | 2547 |
| LLPS-Sus-1510 | Sus scrofa | 95.39 | 0.0 | 2529 |
| LLPS-Mea-4131 | Mesocricetus auratus | 94.86 | 0.0 | 1590 |
| LLPS-Poa-4570 | Pongo abelii | 94.33 | 0.0 | 2509 |
| LLPS-Nol-0075 | Nomascus leucogenys | 94.22 | 0.0 | 1974 |
| LLPS-Gog-1488 | Gorilla gorilla | 94.18 | 0.0 | 2510 |
| LLPS-Pat-3780 | Pan troglodytes | 94.18 | 0.0 | 2506 |
| LLPS-Caj-4345 | Callithrix jacchus | 93.95 | 0.0 | 2506 |
| LLPS-Pap-0849 | Pan paniscus | 93.93 | 0.0 | 1967 |
| LLPS-Hos-1634 | Homo sapiens | 93.84 | 0.0 | 2486 |
| LLPS-Mal-0265 | Mandrillus leucophaeus | 93.8 | 0.0 | 2496 |
| LLPS-Maf-4315 | Macaca fascicularis | 93.73 | 0.0 | 2491 |
| LLPS-Man-1536 | Macaca nemestrina | 93.73 | 0.0 | 2490 |
| LLPS-Mam-3019 | Macaca mulatta | 93.73 | 0.0 | 2491 |
| LLPS-Ova-3786 | Ovis aries | 93.66 | 0.0 | 2468 |
| LLPS-Cea-1663 | Cercocebus atys | 93.65 | 0.0 | 2486 |
| LLPS-Paa-2298 | Papio anubis | 93.65 | 0.0 | 2491 |
| LLPS-Chs-2702 | Chlorocebus sabaeus | 93.5 | 0.0 | 2483 |
| LLPS-Aon-4435 | Aotus nancymaae | 93.5 | 0.0 | 2485 |
| LLPS-Bot-1017 | Bos taurus | 93.5 | 0.0 | 2473 |
| LLPS-Rhb-3132 | Rhinopithecus bieti | 93.5 | 0.0 | 2482 |
| LLPS-Cas-2989 | Carlito syrichta | 93.11 | 0.0 | 2374 |
| LLPS-Eqc-2521 | Equus caballus | 92.73 | 0.0 | 2520 |
| LLPS-Fud-3865 | Fukomys damarensis | 92.06 | 0.0 | 2476 |
| LLPS-Otg-0705 | Otolemur garnettii | 91.62 | 0.0 | 2427 |
| LLPS-Cap-2275 | Cavia porcellus | 91.43 | 0.0 | 2345 |
| LLPS-Orc-0497 | Oryctolagus cuniculus | 91.24 | 0.0 | 2434 |
| LLPS-Mum-3535 | Mus musculus | 90.79 | 0.0 | 2430 |
| LLPS-Ran-1394 | Rattus norvegicus | 90.33 | 0.0 | 2407 |
| LLPS-Ict-0583 | Ictidomys tridecemlineatus | 90.17 | 0.0 | 2411 |
| LLPS-Myl-1476 | Myotis lucifugus | 88.79 | 0.0 | 1536 |
| LLPS-Dar-3694 | Danio rerio | 80.78 | 6e-145 | 447 |
| LLPS-Sah-3901 | Sarcophilus harrisii | 77.91 | 0.0 | 1966 |
| LLPS-Ora-2948 | Ornithorhynchus anatinus | 76.3 | 0.0 | 1859 |
| LLPS-Mod-3387 | Monodelphis domestica | 74.63 | 0.0 | 1953 |
| LLPS-Pes-2155 | Pelodiscus sinensis | 71.1 | 0.0 | 1823 |
| LLPS-Gaga-1047 | Gallus gallus | 69.67 | 0.0 | 1820 |
| LLPS-Tag-3572 | Taeniopygia guttata | 69.3 | 0.0 | 1803 |
| LLPS-Fia-1231 | Ficedula albicollis | 69.08 | 0.0 | 1827 |
| LLPS-Meg-2814 | Meleagris gallopavo | 67.83 | 0.0 | 1763 |
| LLPS-Leo-2020 | Lepisosteus oculatus | 64.65 | 0.0 | 1073 |
| LLPS-Anp-2427 | Anas platyrhynchos | 64.37 | 0.0 | 1391 |
| LLPS-Scf-0622 | Scleropages formosus | 61.24 | 0.0 | 674 |
| LLPS-Xim-3438 | Xiphophorus maculatus | 60.94 | 0.0 | 674 |
| LLPS-Loa-2357 | Loxodonta africana | 58.73 | 0.0 | 1054 |
| LLPS-Xet-3255 | Xenopus tropicalis | 58.45 | 0.0 | 1504 |
| LLPS-Lac-1316 | Latimeria chalumnae | 57.75 | 0.0 | 1042 |
| LLPS-Ten-3027 | Tetraodon nigroviridis | 55.89 | 0.0 | 1003 |
| LLPS-Asm-3639 | Astyanax mexicanus | 55.6 | 0.0 | 1010 |
| LLPS-Icp-2681 | Ictalurus punctatus | 54.36 | 0.0 | 1013 |
| LLPS-Hov-1719 | Hordeum vulgare | 51.02 | 2e-35 | 150 |
| LLPS-Tru-0605 | Triticum urartu | 50.99 | 9e-35 | 149 |
| LLPS-Mae-1510 | Manihot esculenta | 49.67 | 1e-32 | 142 |
| LLPS-Hea-2484 | Helianthus annuus | 49.66 | 9e-33 | 142 |
| LLPS-Amt-1532 | Amborella trichopoda | 49.04 | 1e-34 | 144 |
| LLPS-Ori-2138 | Oryza indica | 48.97 | 4e-32 | 140 |
| LLPS-Nia-0653 | Nicotiana attenuata | 48.63 | 2e-33 | 144 |
| LLPS-Mua-1434 | Musa acuminata | 48.28 | 1e-31 | 139 |
| LLPS-Org-0913 | Oryza glaberrima | 48.28 | 1e-31 | 139 |
| LLPS-Orp-0963 | Oryza punctata | 47.8 | 5e-34 | 146 |
| LLPS-Brd-0807 | Brachypodium distachyon | 46.36 | 6e-32 | 140 |
| LLPS-Orb-1520 | Oryza barthii | 46.25 | 2e-33 | 144 |
| LLPS-Orni-1069 | Oryza nivara | 46.25 | 2e-33 | 144 |
| LLPS-Orgl-0820 | Oryza glumaepatula | 46.25 | 2e-33 | 144 |
| LLPS-Ors-1162 | Oryza sativa | 46.25 | 2e-33 | 144 |
| LLPS-Orr-0812 | Oryza rufipogon | 46.25 | 2e-33 | 144 |
| LLPS-Orm-0120 | Oryza meridionalis | 46.25 | 2e-33 | 144 |
| LLPS-Brr-2253 | Brassica rapa | 45.77 | 3e-31 | 137 |
| LLPS-Glm-2597 | Glycine max | 45.51 | 8e-33 | 142 |
| LLPS-Brn-0576 | Brassica napus | 44.52 | 2e-31 | 137 |
| LLPS-Bro-1827 | Brassica oleracea | 44.52 | 2e-31 | 138 |
| LLPS-Scm-1952 | Scophthalmus maximus | 43.22 | 0.0 | 712 |
| LLPS-Tum-0251 | Tuber melanosporum | 38.02 | 1e-52 | 205 |
| LLPS-Crn-0328 | Cryptococcus neoformans | 37.56 | 8e-59 | 228 |
| LLPS-Met-0108 | Medicago truncatula | 37.2 | 4e-62 | 233 |
| LLPS-Coc-0880 | Corchorus capsularis | 35.64 | 1e-54 | 213 |
| LLPS-Via-1700 | Vigna angularis | 35.56 | 2e-54 | 213 |
| LLPS-Php-2306 | Physcomitrella patens | 35.48 | 3e-55 | 215 |
| LLPS-Art-2966 | Arabidopsis thaliana | 35.33 | 2e-55 | 213 |
| LLPS-Mel-1517 | Melampsora laricipopulina | 35.26 | 8e-49 | 191 |
| LLPS-Vir-0247 | Vigna radiata | 35.23 | 1e-52 | 202 |
| LLPS-Arl-2571 | Arabidopsis lyrata | 35.16 | 7e-55 | 212 |
| LLPS-Gor-1456 | Gossypium raimondii | 34.91 | 7e-54 | 209 |
| LLPS-Pot-1808 | Populus trichocarpa | 34.64 | 5e-56 | 214 |
| LLPS-Thc-1813 | Theobroma cacao | 34.41 | 5e-59 | 225 |
| LLPS-Sei-1553 | Setaria italica | 34.38 | 9e-53 | 205 |
| LLPS-Orbr-1767 | Oryza brachyantha | 34.36 | 2e-53 | 205 |
| LLPS-Prp-0420 | Prunus persica | 34.17 | 9e-51 | 201 |
| LLPS-Sob-0218 | Sorghum bicolor | 34.06 | 6e-59 | 224 |
| LLPS-Sol-0553 | Solanum lycopersicum | 33.33 | 6e-57 | 218 |
| LLPS-Tra-0768 | Triticum aestivum | 32.59 | 1e-53 | 207 |
| LLPS-Pug-1428 | Puccinia graminis | 31.3 | 1e-39 | 163 |
| LLPS-Sot-0205 | Solanum tuberosum | 30.75 | 4e-37 | 156 |
| LLPS-Zem-0177 | Zea mays | 29.81 | 3e-33 | 144 |