LLPS-Caf-0059
SCFD1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Sec1 family domain containing 1 |
| Gene Name: | SCFD1 |
| Ensembl Gene: | ENSCAFG00000012672.4 |
| Ensembl Protein: | ENSCAFP00000042301.1 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, P-body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000046084.1 | ENSCAFP00000042301.1 |
| Ensembl | ENSCAFT00000020184.4 | ENSCAFP00000018722.3 |
| Ensembl | ENSCAFT00000020208.4 | ENSCAFP00000018746.3 |
| UniProt | F1PLS0, F1PLS0_CANLF | |
| GeneBank | AAEX03005649, AAEX03005650 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 AAPAAASIRD RQTVALKRML NFNVPHVKNS TGEPVWKVLI YDRFGQDIIS PLLSVKELRD 60 61 MGITLHLLLH SDRDPIPDVP AVYFVMPTEE NIDRMCQDLR NQLYESYYLN FISAISRSKL 120 121 EDIANAALAA SAVTQVAKVF DQYLNFITLE DDMFVLCNQN KELVSYRAIN RPDITDTEME 180 181 TVMDTIVDSL FCFFVTLGAV PIIRCSRGTA AEMVAVKLDK KLRENLRDAR NSLFTGDTLG 240 241 AGQFSFQRPL LVLVDRNIDL ATPLHHTWTY QALVHDVLDF HLNRVNLEES SGVENSPAGA 300 301 RPKRKNKKSY DLTPVDKFWQ KHKGSPFPEV AESVQQELES YRAQEDEVKR LKSIMGLEGE 360 361 DEGAISMLSD NTAKLTSAVS SLPELLEKKR LIDLHTNVAT AVLEHIKARK LDVYFEYEEK 420 421 IMSKTTLDKS LLDIISDPDA GTPEDKMRLF LIYYISAQQA PSEADLEQYK KALTDAGCNL 480 481 NPLQYIKQWK AFAKMASAPA SYGNTTTKPM GLLSRVMNTG SQFVMEGVKN LVLKQQNLPV 540 541 TRILDNLMEM KSNPETDDYR YFDPKMLRGN DSSVPRNKNP FQEAIVFVVG GGNYIEYQNL 600 601 VDYIKGKQGK HILYGCSELF NATQFIKQLS QLGQK 635 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTGAATT TCAATGTGCC TCATGTTAAA AATAGCACTG GAGAACCAGT ATGGAAGGTG 60 61 CTCATTTATG ACAGATTTGG CCAAGATATC ATCTCTCCGC TGCTGTCTGT GAAAGAGCTG 120 121 AGAGACATGG GAATCACTCT GCATCTGCTT TTGCACTCTG ATCGAGATCC TATTCCAGAT 180 181 GTTCCTGCAG TGTACTTTGT AATGCCAACT GAAGAAAATA TTGACAGAAT GTGCCAGGAT 240 241 CTGCGAAATC AACTCTATGA ATCATATTAT TTAAATTTTA TTTCTGCTAT TTCAAGAAGT 300 301 AAACTGGAAG ATATTGCAAA TGCAGCATTA GCTGCCAGTG CAGTAACACA AGTAGCCAAG 360 361 GTTTTTGATC AGTATCTCAA TTTTATTACT TTGGAAGATG ATATGTTTGT ATTGTGTAAT 420 421 CAAAATAAGG AGCTTGTTTC ATATCGTGCC ATTAACAGAC CAGATATCAC AGACACAGAG 480 481 ATGGAAACTG TTATGGACAC TATTGTTGAC AGCCTCTTCT GCTTTTTTGT TACACTGGGT 540 541 GCTGTTCCTA TAATCAGATG TTCAAGAGGA ACAGCAGCGG AAATGGTAGC AGTGAAACTA 600 601 GATAAGAAAC TTCGAGAAAA TCTAAGAGAT GCAAGGAACA GTCTTTTTAC AGGTGACACA 660 661 CTTGGAGCTG GCCAATTCAG CTTCCAAAGG CCTTTATTAG TCCTTGTTGA CAGAAACATA 720 721 GATTTGGCAA CTCCTTTACA CCATACGTGG ACATATCAAG CCTTGGTGCA TGATGTACTG 780 781 GATTTCCACT TAAACAGAGT TAATTTGGAA GAATCTTCAG GAGTAGAAAA TTCTCCAGCT 840 841 GGTGCTAGAC CAAAAAGAAA AAACAAAAAA TCTTATGATT TAACTCCAGT TGATAAATTT 900 901 TGGCAGAAGC ATAAAGGAAG TCCATTCCCA GAAGTTGCAG AATCAGTTCA GCAAGAACTG 960 961 GAATCTTACA GAGCACAGGA AGATGAGGTT AAACGACTTA AGAGCATTAT GGGACTAGAA 1020 1021 GGGGAAGATG AAGGAGCCAT AAGTATGCTT TCTGACAATA CTGCTAAGCT AACATCAGCA 1080 1081 GTTAGTTCTT TGCCAGAACT CCTTGAAAAA AAAAGACTTA TTGATCTCCA TACAAATGTT 1140 1141 GCCACTGCTG TTTTAGAACA TATAAAGGCA AGAAAACTAG ATGTGTATTT TGAATATGAA 1200 1201 GAAAAAATAA TGAGCAAAAC TACTCTGGAT AAATCTCTTC TAGATATAAT ATCAGACCCT 1260 1261 GATGCAGGAA CGCCAGAAGA TAAAATGAGG CTATTTCTCA TTTATTATAT AAGTGCACAG 1320 1321 CAGGCACCCT CTGAGGCTGA TTTGGAGCAA TACAAAAAAG CTTTAACTGA TGCAGGATGC 1380 1381 AACCTTAATC CCTTACAATA TATCAAACAG TGGAAGGCTT TTGCCAAGAT GGCCTCAGCT 1440 1441 CCTGCCAGCT ATGGTAACAC TACCACTAAA CCAATGGGTC TCTTATCACG AGTCATGAAT 1500 1501 ACAGGATCAC AATTTGTGAT GGAAGGAGTG AAGAACCTGG TATTGAAACA GCAAAATCTA 1560 1561 CCTGTTACTC GTATTTTAGA CAATCTGATG GAGATGAAGT CAAATCCTGA AACTGATGAC 1620 1621 TATAGATATT TTGATCCCAA AATGCTGCGA GGCAATGACA GCTCAGTTCC AAGGAACAAA 1680 1681 AATCCATTCC AGGAGGCAAT TGTTTTCGTG GTGGGAGGAG GCAACTACAT TGAATACCAA 1740 1741 AATCTTGTTG ACTATATAAA GGGGAAGCAA GGCAAACACA TTTTATATGG CTGCAGTGAA 1800 1801 CTTTTTAATG CTACACAGTT CATAAAACAG CTGTCACAAC TTGGACAAAA GTAA 1854 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mup-1693 | Mustela putorius furo | 99.84 | 0.0 | 1274 |
| LLPS-Aim-2936 | Ailuropoda melanoleuca | 99.84 | 0.0 | 1273 |
| LLPS-Urm-2351 | Ursus maritimus | 99.68 | 0.0 | 1261 |
| LLPS-Fec-1815 | Felis catus | 99.53 | 0.0 | 1281 |
| LLPS-Ova-3517 | Ovis aries | 99.52 | 0.0 | 1255 |
| LLPS-Cas-1693 | Carlito syrichta | 99.37 | 0.0 | 1274 |
| LLPS-Eqc-1356 | Equus caballus | 99.36 | 0.0 | 1264 |
| LLPS-Nol-0769 | Nomascus leucogenys | 99.21 | 0.0 | 1268 |
| LLPS-Pat-2252 | Pan troglodytes | 99.21 | 0.0 | 1268 |
| LLPS-Hos-3342 | Homo sapiens | 99.21 | 0.0 | 1268 |
| LLPS-Bot-2689 | Bos taurus | 99.21 | 0.0 | 1264 |
| LLPS-Gog-2354 | Gorilla gorilla | 99.21 | 0.0 | 1268 |
| LLPS-Man-2753 | Macaca nemestrina | 99.2 | 0.0 | 1266 |
| LLPS-Paa-0251 | Papio anubis | 99.2 | 0.0 | 1266 |
| LLPS-Cea-3170 | Cercocebus atys | 99.2 | 0.0 | 1266 |
| LLPS-Chs-2492 | Chlorocebus sabaeus | 99.2 | 0.0 | 1266 |
| LLPS-Maf-1505 | Macaca fascicularis | 99.2 | 0.0 | 1266 |
| LLPS-Poa-3105 | Pongo abelii | 99.04 | 0.0 | 1254 |
| LLPS-Rhb-3310 | Rhinopithecus bieti | 99.04 | 0.0 | 1251 |
| LLPS-Mal-1548 | Mandrillus leucophaeus | 99.04 | 0.0 | 1264 |
| LLPS-Aon-3601 | Aotus nancymaae | 98.89 | 0.0 | 1260 |
| LLPS-Sus-1572 | Sus scrofa | 98.89 | 0.0 | 1262 |
| LLPS-Fud-0006 | Fukomys damarensis | 98.73 | 0.0 | 1261 |
| LLPS-Dio-3275 | Dipodomys ordii | 98.58 | 0.0 | 1267 |
| LLPS-Loa-1645 | Loxodonta africana | 98.57 | 0.0 | 1260 |
| LLPS-Mum-3833 | Mus musculus | 97.78 | 0.0 | 1258 |
| LLPS-Mod-0351 | Monodelphis domestica | 97.72 | 0.0 | 986 |
| LLPS-Ran-0764 | Rattus norvegicus | 97.31 | 0.0 | 1249 |
| LLPS-Myl-2601 | Myotis lucifugus | 97.16 | 0.0 | 1256 |
| LLPS-Sah-1322 | Sarcophilus harrisii | 97.14 | 0.0 | 1246 |
| LLPS-Ora-1455 | Ornithorhynchus anatinus | 96.18 | 0.0 | 1237 |
| LLPS-Caj-0046 | Callithrix jacchus | 95.69 | 0.0 | 1250 |
| LLPS-Anp-1305 | Anas platyrhynchos | 95.17 | 0.0 | 1210 |
| LLPS-Pes-1968 | Pelodiscus sinensis | 94.98 | 0.0 | 1210 |
| LLPS-Orc-0018 | Oryctolagus cuniculus | 94.96 | 0.0 | 1217 |
| LLPS-Otg-0738 | Otolemur garnettii | 94.67 | 0.0 | 1219 |
| LLPS-Tag-0142 | Taeniopygia guttata | 94.32 | 0.0 | 1188 |
| LLPS-Fia-0974 | Ficedula albicollis | 94.17 | 0.0 | 1194 |
| LLPS-Gaga-3635 | Gallus gallus | 94.13 | 0.0 | 1220 |
| LLPS-Mam-0289 | Macaca mulatta | 94.12 | 0.0 | 1182 |
| LLPS-Pap-3877 | Pan paniscus | 93.14 | 0.0 | 1163 |
| LLPS-Mea-1644 | Mesocricetus auratus | 92.02 | 8e-102 | 327 |
| LLPS-Xet-1019 | Xenopus tropicalis | 90.81 | 0.0 | 1188 |
| LLPS-Lac-0199 | Latimeria chalumnae | 90.81 | 0.0 | 1188 |
| LLPS-Icp-3098 | Ictalurus punctatus | 87.96 | 0.0 | 1159 |
| LLPS-Leo-0360 | Lepisosteus oculatus | 87.85 | 0.0 | 1166 |
| LLPS-Dar-1559 | Danio rerio | 87.64 | 0.0 | 1153 |
| LLPS-Scf-1190 | Scleropages formosus | 87.48 | 0.0 | 1141 |
| LLPS-Ict-0539 | Ictidomys tridecemlineatus | 86.49 | 0.0 | 1063 |
| LLPS-Orn-3277 | Oreochromis niloticus | 86.12 | 0.0 | 1132 |
| LLPS-Orl-3538 | Oryzias latipes | 85.9 | 0.0 | 1133 |
| LLPS-Gaa-2612 | Gasterosteus aculeatus | 85.68 | 0.0 | 701 |
| LLPS-Pof-1272 | Poecilia formosa | 85.42 | 0.0 | 1128 |
| LLPS-Xim-3416 | Xiphophorus maculatus | 85.1 | 0.0 | 1127 |
| LLPS-Ten-0290 | Tetraodon nigroviridis | 85.0 | 2e-54 | 188 |
| LLPS-Asm-1103 | Astyanax mexicanus | 84.35 | 0.0 | 991 |
| LLPS-Anc-1581 | Anolis carolinensis | 83.18 | 0.0 | 1068 |
| LLPS-Cap-3409 | Cavia porcellus | 82.69 | 0.0 | 1080 |
| LLPS-Scm-1188 | Scophthalmus maximus | 81.99 | 0.0 | 833 |
| LLPS-Tar-0187 | Takifugu rubripes | 81.3 | 7e-64 | 215 |
| LLPS-Cis-1728 | Ciona savignyi | 58.16 | 0.0 | 730 |
| LLPS-Drm-1747 | Drosophila melanogaster | 57.86 | 0.0 | 731 |
| LLPS-Cii-2157 | Ciona intestinalis | 57.19 | 0.0 | 722 |
| LLPS-Cae-0084 | Caenorhabditis elegans | 46.59 | 0.0 | 568 |
| LLPS-Abg-0206 | Absidia glauca | 43.02 | 8e-161 | 483 |
| LLPS-Sot-1234 | Solanum tuberosum | 41.74 | 4e-142 | 434 |
| LLPS-Gas-0078 | Galdieria sulphuraria | 41.7 | 2e-160 | 484 |
| LLPS-Sol-1253 | Solanum lycopersicum | 41.5 | 3e-143 | 437 |
| LLPS-Tru-1172 | Triticum urartu | 41.2 | 4e-96 | 314 |
| LLPS-Prp-0481 | Prunus persica | 41.19 | 1e-147 | 449 |
| LLPS-Dac-1555 | Daucus carota | 41.19 | 3e-149 | 452 |
| LLPS-Coc-0903 | Corchorus capsularis | 40.9 | 8e-143 | 436 |
| LLPS-Nia-0655 | Nicotiana attenuata | 40.87 | 3e-141 | 432 |
| LLPS-Sob-0883 | Sorghum bicolor | 40.84 | 2e-140 | 430 |
| LLPS-Gor-0336 | Gossypium raimondii | 40.72 | 2e-144 | 440 |
| LLPS-Amt-0154 | Amborella trichopoda | 40.57 | 4e-154 | 466 |
| LLPS-Chc-0147 | Chondrus crispus | 40.54 | 1e-144 | 443 |
| LLPS-Zem-0073 | Zea mays | 40.22 | 4e-136 | 419 |
| LLPS-Mae-1258 | Manihot esculenta | 40.19 | 1e-145 | 444 |
| LLPS-Glm-1315 | Glycine max | 40.16 | 7e-144 | 439 |
| LLPS-Php-0620 | Physcomitrella patens | 40.09 | 5e-144 | 439 |
| LLPS-Sem-0324 | Selaginella moellendorffii | 40.03 | 2e-140 | 429 |
| LLPS-Pot-0729 | Populus trichocarpa | 40.0 | 9e-144 | 439 |
| LLPS-Thc-0774 | Theobroma cacao | 39.91 | 3e-145 | 442 |
| LLPS-Via-0932 | Vigna angularis | 39.88 | 2e-140 | 432 |
| LLPS-Vir-0189 | Vigna radiata | 39.84 | 1e-137 | 422 |
| LLPS-Hea-0790 | Helianthus annuus | 39.81 | 6e-146 | 444 |
| LLPS-Arl-1211 | Arabidopsis lyrata | 39.78 | 1e-146 | 446 |
| LLPS-Cus-0589 | Cucumis sativus | 39.72 | 1e-143 | 438 |
| LLPS-Met-1731 | Medicago truncatula | 39.69 | 3e-140 | 430 |
| LLPS-Phv-1082 | Phaseolus vulgaris | 39.56 | 2e-140 | 430 |
| LLPS-Asn-0385 | Aspergillus nidulans | 39.45 | 5e-122 | 379 |
| LLPS-Tra-1718 | Triticum aestivum | 39.18 | 1e-128 | 400 |
| LLPS-Art-0077 | Arabidopsis thaliana | 39.09 | 5e-142 | 434 |
| LLPS-Brn-3373 | Brassica napus | 39.09 | 6e-139 | 426 |
| LLPS-Sei-1144 | Setaria italica | 38.94 | 6e-130 | 403 |
| LLPS-Viv-1224 | Vitis vinifera | 38.87 | 3e-132 | 408 |
| LLPS-Bro-1824 | Brassica oleracea | 38.8 | 2e-140 | 430 |
| LLPS-Orgl-0887 | Oryza glumaepatula | 38.76 | 3e-133 | 413 |
| LLPS-Spr-0400 | Sporisorium reilianum | 38.67 | 9e-132 | 411 |
| LLPS-Orr-1065 | Oryza rufipogon | 38.66 | 2e-134 | 414 |
| LLPS-Org-1796 | Oryza glaberrima | 38.66 | 2e-134 | 414 |
| LLPS-Osl-0957 | Ostreococcus lucimarinus | 38.66 | 4e-135 | 417 |
| LLPS-Orni-1693 | Oryza nivara | 38.66 | 2e-134 | 414 |
| LLPS-Mel-0298 | Melampsora laricipopulina | 38.63 | 2e-125 | 392 |
| LLPS-Orm-1969 | Oryza meridionalis | 38.58 | 2e-133 | 412 |
| LLPS-Orp-0373 | Oryza punctata | 38.58 | 1e-133 | 412 |
| LLPS-Ori-1024 | Oryza indica | 38.51 | 8e-134 | 413 |
| LLPS-Put-0140 | Puccinia triticina | 38.45 | 4e-118 | 374 |
| LLPS-Ors-0621 | Oryza sativa | 38.35 | 1e-132 | 410 |
| LLPS-Brr-0934 | Brassica rapa | 38.35 | 2e-137 | 423 |
| LLPS-Brd-0159 | Brachypodium distachyon | 37.99 | 3e-122 | 383 |
| LLPS-Chr-1011 | Chlamydomonas reinhardtii | 37.89 | 5e-136 | 419 |
| LLPS-Dos-0816 | Dothistroma septosporum | 37.82 | 1e-150 | 459 |
| LLPS-Mua-1940 | Musa acuminata | 37.75 | 5e-127 | 393 |
| LLPS-Lep-1665 | Leersia perrieri | 37.38 | 5e-120 | 377 |
| LLPS-Zyt-1026 | Zymoseptoria tritici | 37.29 | 2e-148 | 453 |
| LLPS-Miv-1132 | Microbotryum violaceum | 37.24 | 3e-145 | 445 |
| LLPS-Orb-1099 | Oryza barthii | 37.18 | 9e-106 | 338 |
| LLPS-Scc-1273 | Schizosaccharomyces cryophilus | 37.18 | 3e-136 | 419 |
| LLPS-Scj-1155 | Schizosaccharomyces japonicus | 37.12 | 1e-136 | 421 |
| LLPS-Orbr-0031 | Oryza brachyantha | 37.06 | 2e-76 | 256 |
| LLPS-Trr-1041 | Trichoderma reesei | 36.96 | 2e-151 | 461 |
| LLPS-Crn-0170 | Cryptococcus neoformans | 36.56 | 1e-102 | 335 |
| LLPS-Usm-0975 | Ustilago maydis | 36.54 | 1e-124 | 393 |
| LLPS-Asfu-1404 | Aspergillus fumigatus | 36.39 | 4e-146 | 448 |
| LLPS-Fus-1109 | Fusarium solani | 36.27 | 1e-144 | 444 |
| LLPS-Scp-1019 | Schizosaccharomyces pombe | 36.27 | 1e-134 | 416 |
| LLPS-Nef-1222 | Neosartorya fischeri | 36.25 | 4e-145 | 445 |
| LLPS-Trv-0591 | Trichoderma virens | 36.21 | 4e-146 | 447 |
| LLPS-Scs-0281 | Sclerotinia sclerotiorum | 36.13 | 2e-137 | 425 |
| LLPS-Tum-1366 | Tuber melanosporum | 36.09 | 1e-145 | 446 |
| LLPS-Coo-1303 | Colletotrichum orbiculare | 36.05 | 8e-140 | 431 |
| LLPS-Fuo-0596 | Fusarium oxysporum | 36.01 | 7e-145 | 444 |
| LLPS-Lem-0793 | Leptosphaeria maculans | 35.96 | 2e-138 | 427 |
| LLPS-Pug-1109 | Puccinia graminis | 35.88 | 1e-119 | 378 |
| LLPS-Cogr-0830 | Colletotrichum graminicola | 35.77 | 2e-137 | 426 |
| LLPS-Blg-0856 | Blumeria graminis | 35.45 | 3e-141 | 435 |
| LLPS-Nec-1089 | Neurospora crassa | 35.43 | 1e-135 | 421 |
| LLPS-Ast-0737 | Aspergillus terreus | 35.29 | 2e-137 | 425 |
| LLPS-Fuv-0380 | Fusarium verticillioides | 35.29 | 5e-143 | 439 |
| LLPS-Yal-0921 | Yarrowia lipolytica | 35.28 | 2e-114 | 361 |
| LLPS-Asni-1127 | Aspergillus niger | 35.01 | 1e-133 | 415 |
| LLPS-Beb-0280 | Beauveria bassiana | 34.87 | 5e-141 | 434 |
| LLPS-Cog-0088 | Colletotrichum gloeosporioides | 34.82 | 3e-127 | 398 |
| LLPS-Asc-0035 | Aspergillus clavatus | 34.72 | 2e-140 | 433 |
| LLPS-Aso-0016 | Aspergillus oryzae | 34.54 | 1e-140 | 433 |
| LLPS-Asf-0625 | Aspergillus flavus | 34.4 | 4e-140 | 432 |
| LLPS-Gag-0305 | Gaeumannomyces graminis | 34.29 | 1e-137 | 426 |
| LLPS-Map-0359 | Magnaporthe poae | 34.25 | 1e-135 | 421 |
| LLPS-Mao-1067 | Magnaporthe oryzae | 33.98 | 1e-133 | 416 |
| LLPS-Phn-1451 | Phaeosphaeria nodorum | 33.72 | 3e-113 | 360 |
| LLPS-Ved-0008 | Verticillium dahliae | 33.71 | 3e-121 | 382 |
| LLPS-Pytr-1532 | Pyrenophora triticirepentis | 33.48 | 5e-119 | 376 |
| LLPS-Pyt-0315 | Pyrenophora teres | 33.19 | 2e-117 | 372 |
| LLPS-Sac-1588 | Saccharomyces cerevisiae | 32.8 | 8e-112 | 357 |
| LLPS-Kop-0379 | Komagataella pastoris | 32.67 | 2e-106 | 342 |
| LLPS-Asg-0818 | Ashbya gossypii | 32.48 | 2e-106 | 342 |
| LLPS-Cym-0391 | Cyanidioschyzon merolae | 32.3 | 2e-83 | 286 |
| LLPS-Hov-0853 | Hordeum vulgare | 23.71 | 1e-19 | 97.4 |