LLPS-Cae-a084
dgk-3
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Probable diacylglycerol kinase 3 |
| Gene Name: | dgk-3, F54G8.2 |
| Ensembl Gene: | WBGene00000960 |
| Ensembl Protein: | F54G8.2 |
| Organism: | Caenorhabditis elegans |
| Taxa ID: | 6239 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in AFD-neuron mediated thermotaxis. Regulates behavior to environmental temperature. Thought to have a role in olfactory adaptation by affecting diacylglycerol levels. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | F54G8.2 | F54G8.2 |
| UniProt | Q03603, DGK3_CAEEL | |
| GeneBank | Z19155 | CAA79558.3 |
| RefSeq | NM_066630.3 | NP_499031.3 |
| Entrez | 186262 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MLLSPEQFSR LSEYAAYSRR KLKDMLSDFQ QDGKFYSYLS VDGQTINIDG FRAFLIDYFG 60 61 ADLPSDLVDQ LFLSFSKPPI KERRTSLFED AISTVRAKFS ESLSGRMAGL NIAGGSGQQT 120 121 DRSQSSEPQA LVCIPEDDVM GPRVANNDSQ EPRIPLKPLI CTLSLLEADT PENKLDVVFH 180 181 VYDSDGNGFL DKSEIDGIIE QMMNVARYQQ WDTIELEQVI RQMMVDIDYD NDGIVSFDEW 240 241 RRGGLTNIPL LVLLGFDTEM KEDGSHVWRL RHFTKPTYCN ACCSILVGWG GKQGLSCSLC 300 301 KYTVHERCVR SAATNCIRTY SSRQQDKLYH HWQDANATAK CVKCKATVGV FQGKGCRWCH 360 361 NYVHHRCMSA LAQECDLGAL VHHILPPTHI FPAFLERKTS TSLKNHNFSS HSASLLQAVS 420 421 PSNDCRPLLV LVNPKSGGKQ GVKILQKFEY LLNPRQVYDL SKTGPEPGLQ LFSTLKNCNI 480 481 LVCGGDGTIG WVLESMDKMT FPHGRPPVAV LPLGTGNDLA RCLRWGGGYE NENLHKILEQ 540 541 IEKSSLIDMD RWQIKIEITE NKSARRASEK GDTPPYSIIN NYFSIGVDAS IAHRFHVMRE 600 601 KFPEKFNSRM RNKLWYFELG TSETLSSSCK NLHEQIDILC DGESIDLGQD ASLEGIALLN 660 661 IPSIYGGSNL WGRSRKSKGR MPGLFPMKNA EKMQLQTRVQ DIGDGLIELV GLESAMQMGQ 720 721 IKAGVRGARR LSQCSTVVIQ THKSFPMQID GEPWMQPPCI IQITHKNQAK MLVAAAPRKR 780 781 SSWMLLKRQS TNDDN 795 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTGTTAT CACCGGAGCA ATTCTCGCGG CTTAGCGAAT ATGCGGCATA TTCTCGGCGA 60 61 AAGTTGAAAG ATATGTTGAG CGATTTTCAG CAAGACGGGA AGTTCTACTC ATATCTTTCA 120 121 GTTGATGGGC AGACTATAAA TATTGATGGT TTTCGTGCGT TTCTTATCGA TTACTTTGGA 180 181 GCGGATCTTC CCAGTGATCT TGTGGATCAA CTGTTCCTTT CATTCTCCAA GCCACCAATA 240 241 AAAGAGCGGC GAACAAGTCT ATTCGAAGAT GCGATTTCAA CTGTCAGAGC AAAATTCAGT 300 301 GAATCGTTAT CCGGACGAAT GGCTGGACTG AATATTGCAG GAGGATCAGG TCAACAAACG 360 361 GATAGGAGTC AAAGTAGTGA ACCGCAAGCG CTTGTTTGCA TTCCAGAAGA TGATGTAATG 420 421 GGGCCAAGAG TTGCCAACAA TGATTCCCAG GAGCCTAGAA TTCCACTGAA GCCTCTAATT 480 481 TGCACTCTTT CTCTACTTGA AGCCGACACA CCTGAAAACA AACTAGATGT CGTTTTTCAT 540 541 GTCTACGATT CCGATGGAAA TGGGTTTCTG GACAAATCTG AAATCGACGG AATCATTGAG 600 601 CAGATGATGA ATGTGGCAAG ATATCAACAA TGGGATACAA TTGAACTGGA ACAGGTTATT 660 661 CGCCAAATGA TGGTTGACAT TGATTACGAT AATGATGGAA TTGTATCATT CGATGAATGG 720 721 AGACGAGGAG GACTTACAAA TATTCCTTTG CTAGTTCTTC TTGGTTTTGA CACGGAAATG 780 781 AAAGAAGATG GGTCTCATGT TTGGCGTCTT CGTCATTTTA CAAAGCCAAC TTACTGCAAT 840 841 GCGTGCTGCA GTATTCTAGT TGGATGGGGT GGAAAGCAAG GGCTCAGTTG TTCATTATGC 900 901 AAATACACGG TTCATGAAAG ATGTGTCAGA TCGGCTGCCA CAAATTGCAT TCGAACTTAT 960 961 TCAAGTAGAC AGCAAGACAA ACTATATCAT CACTGGCAAG ATGCAAATGC AACCGCTAAA 1020 1021 TGTGTCAAAT GCAAAGCAAC AGTCGGAGTT TTTCAAGGGA AAGGGTGTCG GTGGTGTCAT 1080 1081 AATTATGTTC ATCATAGATG TATGTCTGCA CTTGCTCAAG AGTGTGATCT CGGTGCTTTA 1140 1141 GTCCACCATA TTCTCCCACC AACGCATATA TTTCCTGCAT TTCTGGAACG TAAAACTTCA 1200 1201 ACATCGCTGA AAAATCACAA CTTCAGCTCC CACAGTGCCA GTCTCCTTCA GGCCGTATCT 1260 1261 CCTAGCAATG ATTGTCGTCC TCTCCTAGTT CTTGTCAATC CGAAAAGTGG TGGGAAACAA 1320 1321 GGAGTCAAGA TTCTACAGAA ATTTGAATAT CTTCTCAATC CAAGACAGGT CTATGATTTG 1380 1381 AGTAAAACTG GCCCTGAACC AGGACTTCAA TTATTTTCCA CTTTGAAAAA CTGTAACATT 1440 1441 TTGGTATGTG GAGGTGATGG AACAATTGGA TGGGTATTGG AATCAATGGA TAAAATGACA 1500 1501 TTTCCACATG GAAGACCACC CGTCGCAGTT TTACCATTGG GAACTGGAAA TGATTTGGCA 1560 1561 AGATGTCTTC GATGGGGTGG TGGATATGAA AATGAGAATT TGCATAAAAT ATTGGAACAA 1620 1621 ATTGAAAAAT CAAGTCTAAT TGATATGGAT CGATGGCAGA TTAAAATAGA AATAACAGAG 1680 1681 AATAAAAGTG CAAGAAGAGC AAGTGAAAAA GGAGATACAC CACCATACAG TATCATTAAT 1740 1741 AATTATTTTT CTATTGGAGT GGACGCCTCA ATTGCTCACC GATTCCATGT GATGAGAGAA 1800 1801 AAGTTTCCTG AAAAGTTCAA TAGCCGGATG CGAAACAAGT TGTGGTACTT TGAGTTAGGT 1860 1861 ACAAGTGAGA CCCTATCAAG TTCTTGCAAG AACTTACACG AGCAAATTGA TATTTTGTGC 1920 1921 GATGGAGAAT CAATCGATCT TGGACAAGAT GCATCACTTG AAGGAATTGC TCTTTTGAAT 1980 1981 ATTCCATCAA TTTACGGAGG ATCTAATTTA TGGGGAAGGA GTCGAAAATC TAAAGGAAGA 2040 2041 ATGCCTGGGC TGTTCCCAAT GAAAAATGCC GAGAAAATGC AATTACAGAC AAGAGTTCAA 2100 2101 GATATTGGAG ATGGTCTCAT TGAGTTAGTT GGATTGGAGT CAGCAATGCA AATGGGACAG 2160 2161 ATTAAAGCGG GTGTACGTGG AGCAAGACGG CTTTCTCAAT GTTCAACTGT TGTGATTCAA 2220 2221 ACACACAAAT CATTTCCCAT GCAAATTGAC GGGGAACCAT GGATGCAACC TCCTTGCATC 2280 2281 ATTCAAATCA CACACAAAAA CCAAGCAAAA ATGCTTGTTG CTGCAGCTCC ACGAAAACGA 2340 2341 AGCTCCTGGA TGCTTCTCAA ACGACAGTCC ACAAATGACG ATAACTGA 2388 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | Calcium ion binding | |
Molecular Function | Diacylglycerol kinase activity | |
Molecular Function | NAD+ kinase activity | |
Biological Process | Diacylglycerol metabolic process | |
Biological Process | Glycerolipid metabolic process | |
Biological Process | Intracellular signal transduction | |
Biological Process | Lipid phosphorylation | |
Biological Process | Olfactory behavior | |
Biological Process | Protein kinase C-activating G protein-coupled receptor signaling pathway | |
Biological Process | Regulation of long-term neuronal synaptic plasticity | |
Biological Process | Thermotaxis |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Interaction | ||||
| MIST | ||||
| Drug | ||||
| CTD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Element | ||||
| RAID | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a564 | Homo sapiens | 0.0 | 772 | undefined |
| LLPS-Mum-a559 | Mus musculus | 0.0 | 773 | undefined |