LLPS-Cae-1844
ctl-1
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Catalase-2 |
| Gene Name: | ctl-1, cat-2, Y54G11A.6 |
| Ensembl Gene: | WBGene00000830 |
| Ensembl Protein: | Y54G11A.6.2 |
| Organism: | Caenorhabditis elegans |
| Taxa ID: | 6239 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Responsible for the increase in catalase activity detected in dauer larvae. May act as a general scavenger of hydrogen peroxide in the cytosol, or it may protect cells from the effects of an unknown, dauer-specific metabolic process. Expression may be directly regulated by daf-16. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Y54G11A.6.2 | Y54G11A.6.2 |
| Ensembl | Y54G11A.6.1 | Y54G11A.6.1 |
| UniProt | O61235, CATA2_CAEEL, O18193, Q9XVZ4 | |
| GeneBank | Y14066, U55384, Y14065, AL034488 | AAC14537.1, CAA22458.2, CAA74392.1, CAA74394.1 |
| RefSeq | NM_064578.4 | NP_496979.2 |
| Entrez | 259738 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPNDPSDNQL KTYKETYPKP QVITTSNGAP IYSKTAVLTA GRRGPMLMQD VVYMDEMAHF 60 61 DRERIPERVV HAKGAGAHGY FEVTHDITKY CKADMFNKVG KQTPLLVRFS TVAGESGSAD 120 121 TVRDPRGFSL KFYTEEGNWD LVGNNTPIFF IRDAIHFPNF IHALKRNPQT HMRDPNALFD 180 181 FWMNRPESIH QVMFLYSDRG IPDGFRFMNG YGAHTFKMVN KEGNPIYCKF HFKPAQGSKN 240 241 LDPTDAGKLA SSDPDYAIRD LFNAIESRNF PEWKMFIQVM TFEQAEKWEF NPFDVTKVWP 300 301 HGDYPLIEVG KMVLNRNVKN YFAEVEQAAF CPAHIVPGIE FSPDKMLQGR IFSYTDTHYH 360 361 RLGPNYIQLP VNCPYRSRAH TTQRDGAMAY ESQGDAPNYF PNSFRGYRTR DDVKESTFQT 420 421 TGDVDRYETG DDHNYEQPRQ FWEKVLKEEE RDRLVGNLAS DLGGCLEEIQ NGMVKEFTKV 480 481 HPDFGNALRH QLCQKKH 497 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCAAACG ATCCATCGGA TAATCAACTG AAAACCTACA AGGAGACGTA TCCAAAACCC 60 61 CAAGTGATCA CAACTTCAAA TGGAGCTCCG ATCTACTCGA AGACCGCCGT GCTCACCGCC 120 121 GGGCGGCGTG GCCCAATGCT CATGCAAGAT GTAGTTTATA TGGATGAGAT GGCTCATTTC 180 181 GATCGTGAAC GTATCCCCGA GCGTGTCGTT CATGCCAAGG GAGCCGGAGC CCATGGATAC 240 241 TTCGAGGTCA CCCATGACAT CACCAAGTAC TGTAAGGCCG ATATGTTCAA CAAGGTCGGA 300 301 AAACAGACAC CACTTCTCGT TCGTTTTTCA ACGGTCGCTG GAGAATCGGG ATCCGCTGAT 360 361 ACTGTCCGCG ATCCACGTGG ATTCTCTCTC AAATTCTATA CCGAGGAGGG TAACTGGGAT 420 421 CTGGTTGGAA ATAACACTCC GATCTTCTTC ATTCGTGACG CAATCCACTT TCCGAATTTC 480 481 ATTCATGCCC TGAAGCGCAA TCCACAGACT CACATGAGGG ATCCGAATGC GCTCTTCGAT 540 541 TTCTGGATGA ATCGCCCTGA ATCCATTCAT CAGGTGATGT TCCTCTACTC GGATCGTGGA 600 601 ATTCCTGATG GATTCCGTTT TATGAATGGA TACGGAGCGC ATACTTTCAA GATGGTCAAC 660 661 AAGGAGGGAA ATCCGATTTA TTGTAAATTC CATTTCAAGC CTGCTCAAGG TTCCAAGAAT 720 721 CTCGATCCAA CTGACGCTGG AAAGCTCGCC TCTTCGGATC CAGACTATGC GATCCGCGAC 780 781 CTGTTCAATG CCATTGAGTC AAGAAATTTC CCGGAATGGA AGATGTTCAT TCAAGTGATG 840 841 ACATTCGAAC AAGCTGAGAA ATGGGAGTTC AATCCATTTG ATGTCACTAA AGTTTGGCCA 900 901 CACGGTGATT ACCCACTGAT CGAGGTCGGC AAGATGGTGC TGAACAGGAA TGTGAAGAAT 960 961 TATTTCGCTG AGGTCGAACA AGCCGCCTTC TGCCCGGCCC ACATCGTCCC AGGAATCGAG 1020 1021 TTCTCGCCAG ACAAGATGCT CCAAGGGCGT ATCTTCTCCT ACACGGACAC GCATTACCAT 1080 1081 CGCCTTGGAC CAAACTACAT TCAGCTTCCA GTCAACTGCC CGTACCGCTC CCGTGCTCAT 1140 1141 ACCACTCAAC GCGATGGTGC AATGGCTTAT GAAAGCCAGG GAGATGCGCC GAATTACTTC 1200 1201 CCGAACAGTT TCCGCGGATA CCGTACTCGT GATGATGTGA AGGAGTCGAC ATTTCAGACG 1260 1261 ACTGGAGATG TTGATCGTTA TGAGACTGGA GACGATCACA ACTACGAGCA GCCACGTCAG 1320 1321 TTCTGGGAGA AAGTGCTCAA GGAGGAGGAG AGAGATCGGC TCGTTGGGAA TTTGGCTAGT 1380 1381 GATTTGGGTG GCTGTTTGGA GGAAATTCAA AATGGAATGG TCAAAGAGTT CACGAAAGTT 1440 1441 CATCCGGATT TCGGAAATGC TCTTCGCCAT CAGCTCTGCC AGAAGAAGCA TTAA 1494 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Peroxisome | |
Molecular Function | Catalase activity | |
Molecular Function | Heme binding | |
Molecular Function | Metal ion binding | |
Biological Process | Hydrogen peroxide catabolic process | |
Biological Process | Response to hydrogen peroxide |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| PTM | ||||
| EPSD | ||||
| Interaction | ||||
| MIST | ||||
| Drug | ||||
| CTD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Element | ||||
| RAID | microRNA.org | |||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Anc-1501 | Anolis carolinensis | 71.21 | 3e-176 | 506 |
| LLPS-Xet-2600 | Xenopus tropicalis | 63.38 | 0.0 | 657 |
| LLPS-Bot-2789 | Bos taurus | 58.22 | 0.0 | 575 |
| LLPS-Sol-2267 | Solanum lycopersicum | 57.89 | 1e-35 | 145 |
| LLPS-Cus-1583 | Cucumis sativus | 55.43 | 1e-62 | 216 |
| LLPS-Ora-3046 | Ornithorhynchus anatinus | 54.95 | 1e-27 | 110 |
| LLPS-Icp-4181 | Ictalurus punctatus | 54.21 | 5e-104 | 322 |
| LLPS-Drm-2359 | Drosophila melanogaster | 54.03 | 0.0 | 546 |
| LLPS-Orbr-0477 | Oryza brachyantha | 49.48 | 1e-133 | 404 |
| LLPS-Lep-0977 | Leersia perrieri | 49.21 | 6e-134 | 404 |
| LLPS-Mel-0606 | Melampsora laricipopulina | 48.55 | 1e-147 | 440 |
| LLPS-Aso-1095 | Aspergillus oryzae | 48.35 | 1e-154 | 458 |
| LLPS-Dac-0788 | Daucus carota | 48.23 | 4e-139 | 417 |
| LLPS-Scc-0649 | Schizosaccharomyces cryophilus | 47.89 | 6e-141 | 422 |
| LLPS-Coo-0492 | Colletotrichum orbiculare | 47.64 | 1e-148 | 442 |
| LLPS-Ved-0220 | Verticillium dahliae | 47.55 | 8e-147 | 440 |
| LLPS-Asni-0577 | Aspergillus niger | 47.52 | 3e-150 | 446 |
| LLPS-Asn-1375 | Aspergillus nidulans | 47.52 | 1e-146 | 437 |
| LLPS-Sem-1168 | Selaginella moellendorffii | 47.47 | 1e-136 | 410 |
| LLPS-Zyt-1370 | Zymoseptoria tritici | 46.96 | 4e-144 | 432 |
| LLPS-Trv-1343 | Trichoderma virens | 46.88 | 4e-152 | 451 |
| LLPS-Pytr-1381 | Pyrenophora triticirepentis | 46.67 | 2e-135 | 410 |
| LLPS-Caf-4475 | Canis familiaris | 46.63 | 2e-137 | 411 |
| LLPS-Asf-1182 | Aspergillus flavus | 46.51 | 6e-108 | 344 |
| LLPS-Mua-0274 | Musa acuminata | 45.68 | 7e-138 | 414 |
| LLPS-Asc-0791 | Aspergillus clavatus | 45.5 | 1e-108 | 346 |
| LLPS-Ast-1183 | Aspergillus terreus | 45.48 | 1e-110 | 351 |
| LLPS-Arl-2385 | Arabidopsis lyrata | 45.48 | 5e-127 | 400 |
| LLPS-Orp-0071 | Oryza punctata | 45.25 | 1e-134 | 406 |
| LLPS-Org-2085 | Oryza glaberrima | 45.25 | 1e-134 | 406 |
| LLPS-Orb-1492 | Oryza barthii | 45.25 | 8e-135 | 406 |
| LLPS-Brr-0323 | Brassica rapa | 45.13 | 5e-146 | 435 |
| LLPS-Fuo-1595 | Fusarium oxysporum | 45.13 | 3e-136 | 410 |
| LLPS-Brn-2525 | Brassica napus | 45.13 | 3e-146 | 436 |
| LLPS-Pot-2775 | Populus trichocarpa | 45.1 | 9e-142 | 425 |
| LLPS-Ors-0478 | Oryza sativa | 45.02 | 4e-134 | 404 |
| LLPS-Orm-1020 | Oryza meridionalis | 45.02 | 4e-134 | 404 |
| LLPS-Orr-1878 | Oryza rufipogon | 45.02 | 4e-134 | 404 |
| LLPS-Orni-1280 | Oryza nivara | 45.02 | 4e-134 | 404 |
| LLPS-Ori-2351 | Oryza indica | 45.02 | 4e-134 | 404 |
| LLPS-Orgl-0688 | Oryza glumaepatula | 45.02 | 4e-134 | 404 |
| LLPS-Nef-0638 | Neosartorya fischeri | 44.72 | 1e-108 | 347 |
| LLPS-Asfu-1582 | Aspergillus fumigatus | 44.72 | 2e-109 | 348 |
| LLPS-Fuv-0206 | Fusarium verticillioides | 44.57 | 7e-131 | 396 |
| LLPS-Bro-1246 | Brassica oleracea | 44.16 | 4e-142 | 425 |
| LLPS-Phn-0964 | Phaeosphaeria nodorum | 44.14 | 2e-127 | 389 |
| LLPS-Hea-2078 | Helianthus annuus | 44.0 | 2e-143 | 428 |
| LLPS-Art-1163 | Arabidopsis thaliana | 43.95 | 2e-142 | 426 |
| LLPS-Gor-1051 | Gossypium raimondii | 43.95 | 6e-145 | 432 |
| LLPS-Glm-1848 | Glycine max | 43.88 | 5e-143 | 427 |
| LLPS-Nia-2312 | Nicotiana attenuata | 43.64 | 2e-141 | 423 |
| LLPS-Lem-0904 | Leptosphaeria maculans | 43.27 | 2e-105 | 338 |
| LLPS-Sot-1938 | Solanum tuberosum | 42.95 | 2e-137 | 413 |
| LLPS-Tum-1156 | Tuber melanosporum | 42.83 | 1e-118 | 372 |
| LLPS-Dos-1274 | Dothistroma septosporum | 42.55 | 2e-104 | 335 |
| LLPS-Mae-2299 | Manihot esculenta | 42.46 | 5e-134 | 404 |
| LLPS-Tra-2146 | Triticum aestivum | 42.41 | 1e-136 | 411 |
| LLPS-Mao-0711 | Magnaporthe oryzae | 42.12 | 8e-108 | 343 |
| LLPS-Scs-0330 | Sclerotinia sclerotiorum | 41.76 | 5e-109 | 347 |
| LLPS-Php-0548 | Physcomitrella patens | 40.84 | 5e-131 | 396 |
| LLPS-Blg-1301 | Blumeria graminis | 40.82 | 2e-100 | 325 |
| LLPS-Beb-1049 | Beauveria bassiana | 40.43 | 1e-106 | 340 |
| LLPS-Pug-1457 | Puccinia graminis | 40.31 | 1e-99 | 316 |
| LLPS-Pyt-1162 | Pyrenophora teres | 39.95 | 1e-101 | 328 |
| LLPS-Trr-1194 | Trichoderma reesei | 39.5 | 1e-104 | 335 |
| LLPS-Sac-1441 | Saccharomyces cerevisiae | 38.94 | 1e-114 | 357 |
| LLPS-Chc-0889 | Chondrus crispus | 38.61 | 2e-101 | 321 |
| LLPS-Tru-0313 | Triticum urartu | 34.81 | 2e-94 | 303 |
| LLPS-Put-0752 | Puccinia triticina | 31.64 | 2e-51 | 189 |