LLPS-Cae-1304
sav-1

▼ OVERVIEW

Status: Unreviewed
Protein Name: SAlVador (Cell proliferation regulator) homolog
Gene Name: sav-1, CELE_T10H10.3, T10H10.3
Ensembl Gene: WBGene00020427
Ensembl Protein: T10H10.3
Organism: Caenorhabditis elegans
Taxa ID: 6239
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblT10H10.3T10H10.3
UniProtP91441, P91441_CAEEL
GeneBankBX284606CCD61192.1
RefSeqNM_076017.5NP_508418.3
Entrez188402

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLFSRRKPVT  SVEGTQGKYV  KRESPPTVPS  LAATAVSRTR  RSPIAASTLI  LSSVPPPPTS  60
61    TPPPEIQMYH  SENPSVEEAD  DLDDIEHQED  FFDLNDLKEM  EFERLHSRST  ASENDVYTEP  120
121   SDEPSTSFGA  RNNYVLSSRS  FNRGALRYVP  RKSLTASHSI  GNVEQGTREL  SVIEKRLASP  180
181   QPPRFQSLQT  LPSEHLMTIQ  QYRSSCDCSS  DIPLPENWAV  EFTTENQPYY  VDHANRRTHW  240
241   VHPFVHESLK  PGWKKFFDPE  KGVFYYHEEM  KRTQYEHPGI  SNPIFRTESV  NVASRSQVDL  300
301   NANLHIIEEK  ELPPWLLMYA  QSDSSLDHLL  EWDLFNFEQL  TEYEHLMMKL  YKQEVFDIVK  360
361   KYEKKRNVLN  REIHRRDVSR  PPPARINEN  389
Nucleotide CDS Sequence (FASTA)
1     ATGCTATTCT  CTCGAAGGAA  ACCTGTAACG  TCGGTAGAAG  GAACACAGGG  TAAATACGTG  60
61    AAACGAGAGA  GCCCACCAAC  AGTTCCGTCA  CTGGCAGCAA  CTGCTGTGAG  CAGAACTCGA  120
121   AGAAGTCCTA  TTGCCGCCTC  GACACTGATT  TTGTCATCCG  TACCCCCACC  ACCAACAAGT  180
181   ACACCACCGC  CTGAAATTCA  GATGTATCAT  TCGGAAAATC  CAAGTGTCGA  AGAAGCCGAT  240
241   GATCTGGATG  ATATTGAGCA  TCAAGAAGAC  TTTTTCGATC  TGAATGATTT  GAAGGAAATG  300
301   GAATTTGAAA  GACTTCATTC  AAGATCTACG  GCTAGTGAAA  ACGATGTCTA  CACGGAGCCA  360
361   TCCGACGAGC  CGTCTACTTC  ATTTGGAGCA  CGAAACAACT  ACGTACTCTC  TTCAAGAAGC  420
421   TTCAACAGAG  GAGCACTGCG  GTATGTTCCA  AGGAAGTCAC  TGACAGCCTC  ACACTCGATT  480
481   GGTAATGTAG  AACAGGGCAC  ACGGGAACTC  AGCGTGATTG  AAAAAAGGCT  GGCTTCCCCT  540
541   CAACCGCCAA  GATTCCAATC  GCTTCAAACT  CTTCCCAGTG  AACATTTGAT  GACAATTCAA  600
601   CAATATCGAT  CTTCTTGTGA  CTGTTCAAGT  GATATTCCAC  TGCCGGAAAA  CTGGGCTGTA  660
661   GAATTCACCA  CAGAAAACCA  GCCATACTAC  GTTGATCATG  CCAACCGGCG  AACTCATTGG  720
721   GTTCATCCTT  TTGTTCATGA  AAGTCTCAAG  CCTGGATGGA  AGAAGTTTTT  CGATCCGGAG  780
781   AAGGGAGTTT  TTTACTATCA  TGAAGAAATG  AAGAGAACAC  AATACGAGCA  CCCTGGTATA  840
841   TCAAATCCAA  TTTTTCGAAC  GGAATCTGTA  AATGTTGCTA  GCCGCTCCCA  AGTGGATTTG  900
901   AATGCCAATC  TGCACATTAT  AGAGGAGAAA  GAACTGCCAC  CCTGGCTACT  GATGTATGCT  960
961   CAATCGGATT  CGTCGCTGGA  CCACCTGTTA  GAGTGGGATT  TGTTCAATTT  CGAGCAGCTG  1020
1021  ACGGAATACG  AACACCTGAT  GATGAAGCTT  TACAAACAAG  AAGTGTTCGA  TATTGTGAAA  1080
1081  AAATATGAGA  AGAAGCGAAA  TGTTTTGAAC  CGAGAGATTC  ATCGACGGGA  TGTCTCAAGA  1140
1141  CCGCCCCCTG  CGAGGATCAA  CGAGAATTGA  1170

▼ ANNOTATION

Disorder
IUPred2A
Interaction
MIST
Physicochemical
Compute pI/MwAAindex
Function
iEKPD
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cis-2079Ciona savignyi40.795e-1270.1
LLPS-Ora-1293Ornithorhynchus anatinus37.363e-28 118
LLPS-Gaga-2321Gallus gallus36.782e-27 115
LLPS-Meg-2771Meleagris gallopavo36.782e-27 115
LLPS-Scf-2668Scleropages formosus36.722e-25 110
LLPS-Tar-0860Takifugu rubripes36.723e-26 112
LLPS-Sah-4047Sarcophilus harrisii36.211e-27 116
LLPS-Lac-2230Latimeria chalumnae36.113e-26 112
LLPS-Orl-3528Oryzias latipes36.077e-26 111
LLPS-Ten-2225Tetraodon nigroviridis36.076e-26 111
LLPS-Orn-2252Oreochromis niloticus36.073e-26 112
LLPS-Gaa-2190Gasterosteus aculeatus35.753e-26 112
LLPS-Asm-0136Astyanax mexicanus35.678e-23 102
LLPS-Icp-1508Ictalurus punctatus35.633e-23 103
LLPS-Dio-2753Dipodomys ordii35.262e-27 116
LLPS-Ran-1958Rattus norvegicus35.262e-27 115
LLPS-Mea-2219Mesocricetus auratus35.261e-27 116
LLPS-Mum-4157Mus musculus35.262e-27 116
LLPS-Anc-1845Anolis carolinensis35.261e-25 110
LLPS-Mod-0171Monodelphis domestica35.268e-28 117
LLPS-Leo-3723Lepisosteus oculatus35.163e-26 112
LLPS-Loa-0069Loxodonta africana35.111e-1889.7
LLPS-Aim-1002Ailuropoda melanoleuca34.941e-26 113
LLPS-Bot-4241Bos taurus34.681e-26 113
LLPS-Ova-0749Ovis aries34.685e-27 114
LLPS-Mup-2466Mustela putorius furo34.684e-27 114
LLPS-Mal-0386Mandrillus leucophaeus34.684e-27 114
LLPS-Paa-4740Papio anubis34.684e-27 114
LLPS-Cea-4695Cercocebus atys34.686e-27 114
LLPS-Aon-0512Aotus nancymaae34.685e-27 114
LLPS-Sus-3789Sus scrofa34.688e-27 114
LLPS-Maf-1070Macaca fascicularis34.684e-27 114
LLPS-Gog-2813Gorilla gorilla34.683e-27 114
LLPS-Mam-1679Macaca mulatta34.684e-27 114
LLPS-Cap-2983Cavia porcellus34.686e-27 114
LLPS-Nol-0228Nomascus leucogenys34.684e-27 114
LLPS-Cas-3383Carlito syrichta34.686e-27 114
LLPS-Man-0609Macaca nemestrina34.684e-27 114
LLPS-Fec-0841Felis catus34.685e-27 114
LLPS-Urm-1503Ursus maritimus34.684e-27 114
LLPS-Pap-2493Pan paniscus34.686e-27 114
LLPS-Pat-2729Pan troglodytes34.684e-27 114
LLPS-Hos-0308Homo sapiens34.684e-27 114
LLPS-Rhb-4446Rhinopithecus bieti34.684e-27 114
LLPS-Otg-1862Otolemur garnettii34.625e-0859.3
LLPS-Myl-0823Myotis lucifugus34.485e-27 114
LLPS-Caj-2416Callithrix jacchus34.485e-27 114
LLPS-Fia-2459Ficedula albicollis34.355e-1579.3
LLPS-Tag-0452Taeniopygia guttata34.123e-26 111
LLPS-Fud-4322Fukomys damarensis34.11e-26 113
LLPS-Caf-1024Canis familiaris34.11e-26 113
LLPS-Poa-4565Pongo abelii34.11e-26 113
LLPS-Orc-3587Oryctolagus cuniculus34.11e-26 113
LLPS-Xet-1218Xenopus tropicalis33.93e-25 109
LLPS-Xim-3951Xiphophorus maculatus33.335e-22 100
LLPS-Pof-1403Poecilia formosa33.143e-25 109
LLPS-Dar-4107Danio rerio32.948e-23 102
LLPS-Eqc-2617Equus caballus32.714e-1374.7
LLPS-Drm-0266Drosophila melanogaster31.864e-27 117
LLPS-Anp-1465Anas platyrhynchos30.771e-0654.7
LLPS-Ict-1320Ictidomys tridecemlineatus30.02e-0653.9
LLPS-Chs-3006Chlorocebus sabaeus29.672e-0653.9
LLPS-Pes-1500Pelodiscus sinensis28.461e-0655.1