LLPS-Cae-1139
mai-2

▼ OVERVIEW

Status: Unreviewed
Protein Name: ATPase inhibitor mai-2, mitochondrial; ATP synthase F1 subunit epsilon
Gene Name: mai-2, B0546.1
Ensembl Gene: WBGene00015248
Ensembl Protein: B0546.1.1
Organism: Caenorhabditis elegans
Taxa ID: 6239
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria. Activity is pH dependent.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblB0546.1.1B0546.1.1
EnsemblB0546.1.2B0546.1.2
UniProtO44441, ATIF2_CAEEL
GeneBankAF326939, FO080229CCD62188.1, AAG49389.1
RefSeqNM_067935.6NP_500336.1
Entrez177106

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLSVSRAATR  MTGMVARFSA  GGHGDGAGRG  GGSGGSIRDA  GGAFGKMEAA  REDEYFYKKQ  60
61    KAQLQELREH  IQEEVKHHEG  QLENHKKVLE  RHQQRISEIE  AQERALGKE  109
Nucleotide CDS Sequence (FASTA)
1     ATGCTCAGCG  TTTCAAGAGC  CGCCACTCGC  ATGACCGGAA  TGGTCGCCCG  CTTCTCCGCC  60
61    GGAGGACACG  GAGACGGAGC  CGGACGCGGA  GGAGGCTCCG  GTGGATCGAT  CCGCGACGCC  120
121   GGAGGTGCGT  TCGGAAAGAT  GGAGGCCGCC  CGCGAGGACG  AGTACTTCTA  CAAGAAGCAG  180
181   AAGGCTCAAC  TTCAGGAACT  CCGCGAGCAC  ATCCAGGAGG  AGGTCAAGCA  TCACGAGGGA  240
241   CAACTCGAGA  ATCACAAGAA  GGTGCTCGAA  CGCCATCAAC  AACGCATTTC  GGAGATCGAA  300
301   GCCCAGGAGC  GTGCCCTCGG  AAAGGAATAA  330

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Mitochondrion
Reference proteome
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrion
Molecular Function
ATPase binding
Molecular Function
ATPase inhibitor activity
Biological Process
Heme biosynthetic process
Biological Process
Negative regulation of ATPase activity
Biological Process
Negative regulation of nucleotide metabolic process

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Interaction
MIST
Drug
CTD
Physicochemical
AAindex
Function
PIRSF

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anc-0961Anolis carolinensis45.284e-0748.5
LLPS-Mum-2572Mus musculus44.648e-0850.8
LLPS-Gog-3220Gorilla gorilla43.49e-0644.7
LLPS-Aon-2757Aotus nancymaae43.49e-0644.7
LLPS-Pat-0599Pan troglodytes43.41e-0544.7
LLPS-Pap-3244Pan paniscus43.41e-0544.7
LLPS-Hos-1774Homo sapiens43.41e-0544.7
LLPS-Nol-0222Nomascus leucogenys43.41e-0544.7
LLPS-Poa-2923Pongo abelii43.41e-0544.7
LLPS-Mea-3548Mesocricetus auratus43.19e-0850.4
LLPS-Icp-3271Ictalurus punctatus42.863e-0748.9
LLPS-Gaga-0684Gallus gallus42.861e-0647.0
LLPS-Xet-0088Xenopus tropicalis42.862e-0852.4
LLPS-Eqc-1775Equus caballus42.867e-0748.1
LLPS-Chs-4710Chlorocebus sabaeus41.078e-0645.1
LLPS-Maf-1834Macaca fascicularis41.079e-0644.7
LLPS-Cea-1642Cercocebus atys41.079e-0644.7
LLPS-Paa-0859Papio anubis41.079e-0644.7
LLPS-Mal-2385Mandrillus leucophaeus41.079e-0644.7
LLPS-Scf-1981Scleropages formosus41.072e-0646.6
LLPS-Otg-1001Otolemur garnettii41.077e-0645.1
LLPS-Orn-1283Oreochromis niloticus41.072e-0647.0
LLPS-Rhb-2903Rhinopithecus bieti41.078e-0645.1
LLPS-Man-3667Macaca nemestrina41.079e-0644.7
LLPS-Ict-0121Ictidomys tridecemlineatus41.076e-0645.1
LLPS-Fud-0416Fukomys damarensis40.04e-0645.8
LLPS-Ran-1426Rattus norvegicus40.07e-0748.1
LLPS-Orc-0606Oryctolagus cuniculus40.08e-0747.8
LLPS-Gaa-0217Gasterosteus aculeatus39.298e-0645.1
LLPS-Cap-1245Cavia porcellus39.294e-0645.8