LLPS-Cae-0467
pfd-5
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Probable prefoldin subunit 5 |
| Gene Name: | pfd-5, R151.9 |
| Ensembl Gene: | WBGene00020112 |
| Ensembl Protein: | R151.9 |
| Organism: | Caenorhabditis elegans |
| Taxa ID: | 6239 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, P-body | Predicted from orthologs | (View) |
▼ FUNCTION
| Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | R151.9 | R151.9 |
| UniProt | Q21993, PFD5_CAEEL | |
| GeneBank | FO081317, AF303258 | CCD70764.1, AAG50216.1 |
| RefSeq | NM_066181.5 | NP_498582.1 |
| Entrez | 176013 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAEEPKGVPL SELSLQQLGE LQKNCEQELN FFQESFNALK GLLTRNEKSI SALDDVKIAT 60 61 AGHTALIPLS ESLYIRAELS DPSKHLVEIG TGYFVELDRE KAKAIFDRKK EHITKQVETV 120 121 EGILKEKRRT RAYISDAFQT KVQSQLATMN TQ 152 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAGAAG AACCGAAAGG AGTACCGCTG TCAGAGCTCA GCTTGCAACA ACTCGGAGAA 60 61 CTCCAGAAGA ATTGCGAACA AGAATTAAAC TTCTTCCAGG AGTCTTTCAA TGCTCTTAAA 120 121 GGTCTTTTAA CGCGGAACGA AAAAAGTATT TCTGCTTTGG ACGATGTGAA AATTGCAACT 180 181 GCAGGACATA CAGCTCTCAT TCCACTTTCT GAATCGCTCT ACATCCGTGC TGAACTATCT 240 241 GATCCATCAA AGCATTTGGT GGAGATCGGA ACTGGATACT TCGTGGAGCT GGACCGCGAG 300 301 AAAGCCAAAG CAATTTTTGA CCGTAAAAAG GAACATATTA CAAAGCAGGT TGAGACAGTT 360 361 GAGGGAATTC TGAAAGAGAA GCGAAGAACT CGGGCCTATA TTTCGGACGC ATTCCAGACC 420 421 AAGGTTCAGT CTCAACTCGC CACGATGAAT ACACAATAA 459 |
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Prefoldin complex | |
Molecular Function | Unfolded protein binding | |
Biological Process | Protein folding |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Zem-1001 | Zea mays | 45.45 | 9e-06 | 45.4 |
| LLPS-Mae-0283 | Manihot esculenta | 42.68 | 1e-12 | 65.9 |
| LLPS-Met-1891 | Medicago truncatula | 41.18 | 2e-14 | 71.2 |
| LLPS-Sol-0242 | Solanum lycopersicum | 40.24 | 1e-12 | 66.2 |
| LLPS-Glm-2391 | Glycine max | 40.24 | 4e-13 | 67.4 |
| LLPS-Sot-1678 | Solanum tuberosum | 40.24 | 1e-12 | 66.2 |
| LLPS-Pot-1350 | Populus trichocarpa | 40.24 | 4e-12 | 64.7 |
| LLPS-Coc-1526 | Corchorus capsularis | 40.24 | 4e-12 | 64.7 |
| LLPS-Lep-1306 | Leersia perrieri | 39.34 | 7e-06 | 46.2 |
| LLPS-Hea-0588 | Helianthus annuus | 39.29 | 2e-14 | 70.9 |
| LLPS-Gor-0376 | Gossypium raimondii | 39.02 | 3e-12 | 65.1 |
| LLPS-Nia-1648 | Nicotiana attenuata | 39.02 | 2e-12 | 65.5 |
| LLPS-Cog-0649 | Colletotrichum gloeosporioides | 38.64 | 1e-13 | 68.6 |
| LLPS-Ori-0337 | Oryza indica | 37.84 | 5e-11 | 61.2 |
| LLPS-Thc-0008 | Theobroma cacao | 37.8 | 3e-11 | 62.4 |
| LLPS-Arl-2943 | Arabidopsis lyrata | 37.8 | 7e-11 | 60.5 |
| LLPS-Sei-1143 | Setaria italica | 37.8 | 1e-12 | 66.2 |
| LLPS-Ors-0955 | Oryza sativa | 37.8 | 5e-12 | 64.3 |
| LLPS-Viv-0400 | Vitis vinifera | 37.8 | 2e-12 | 65.5 |
| LLPS-Sob-0077 | Sorghum bicolor | 37.8 | 6e-12 | 63.9 |
| LLPS-Phv-1286 | Phaseolus vulgaris | 36.9 | 4e-13 | 67.4 |
| LLPS-Mua-1273 | Musa acuminata | 36.59 | 3e-10 | 58.9 |
| LLPS-Art-2518 | Arabidopsis thaliana | 36.59 | 1e-10 | 60.1 |
| LLPS-Pes-1809 | Pelodiscus sinensis | 36.26 | 2e-13 | 67.0 |
| LLPS-Scj-0007 | Schizosaccharomyces japonicus | 36.11 | 1e-09 | 57.0 |
| LLPS-Sac-0151 | Saccharomyces cerevisiae | 36.04 | 1e-12 | 65.9 |
| LLPS-Asfu-1197 | Aspergillus fumigatus | 36.0 | 5e-06 | 46.6 |
| LLPS-Usm-1046 | Ustilago maydis | 35.85 | 2e-12 | 65.9 |
| LLPS-Cii-1499 | Ciona intestinalis | 35.59 | 7e-17 | 77.8 |
| LLPS-Aon-0428 | Aotus nancymaae | 35.37 | 1e-09 | 57.4 |
| LLPS-Dac-0986 | Daucus carota | 35.37 | 2e-10 | 59.7 |
| LLPS-Brd-2196 | Brachypodium distachyon | 35.37 | 8e-11 | 60.8 |
| LLPS-Tra-1876 | Triticum aestivum | 35.37 | 6e-11 | 61.2 |
| LLPS-Amt-1243 | Amborella trichopoda | 35.29 | 1e-10 | 60.5 |
| LLPS-Asm-1379 | Astyanax mexicanus | 35.04 | 6e-16 | 75.5 |
| LLPS-Meg-2626 | Meleagris gallopavo | 34.78 | 1e-07 | 50.1 |
| LLPS-Osl-1109 | Ostreococcus lucimarinus | 34.78 | 5e-11 | 60.8 |
| LLPS-Brn-0009 | Brassica napus | 34.43 | 7e-13 | 66.6 |
| LLPS-Brr-0248 | Brassica rapa | 34.43 | 5e-13 | 67.4 |
| LLPS-Bro-1802 | Brassica oleracea | 34.43 | 1e-12 | 66.6 |
| LLPS-Scp-1239 | Schizosaccharomyces pombe | 34.11 | 5e-09 | 55.5 |
| LLPS-Chs-0737 | Chlorocebus sabaeus | 33.96 | 3e-13 | 68.2 |
| LLPS-Xet-1281 | Xenopus tropicalis | 33.9 | 3e-16 | 75.9 |
| LLPS-Leo-1898 | Lepisosteus oculatus | 33.87 | 1e-15 | 74.7 |
| LLPS-Ova-0699 | Ovis aries | 33.87 | 1e-15 | 74.7 |
| LLPS-Scf-0745 | Scleropages formosus | 33.61 | 5e-16 | 75.5 |
| LLPS-Cym-0949 | Cyanidioschyzon merolae | 33.33 | 2e-08 | 54.7 |
| LLPS-Tar-0412 | Takifugu rubripes | 33.06 | 2e-15 | 73.9 |
| LLPS-Xim-1425 | Xiphophorus maculatus | 33.06 | 2e-14 | 71.2 |
| LLPS-Prp-1245 | Prunus persica | 33.06 | 5e-13 | 67.0 |
| LLPS-Ten-3046 | Tetraodon nigroviridis | 33.06 | 2e-16 | 76.3 |
| LLPS-Gaa-2981 | Gasterosteus aculeatus | 32.77 | 1e-16 | 77.0 |
| LLPS-Dar-1518 | Danio rerio | 32.77 | 3e-15 | 73.6 |
| LLPS-Drm-1955 | Drosophila melanogaster | 32.69 | 2e-13 | 68.6 |
| LLPS-Gas-0637 | Galdieria sulphuraria | 32.48 | 2e-16 | 76.6 |
| LLPS-Mao-0963 | Magnaporthe oryzae | 32.47 | 2e-10 | 59.7 |
| LLPS-Zyt-1181 | Zymoseptoria tritici | 32.47 | 3e-09 | 56.6 |
| LLPS-Myl-1537 | Myotis lucifugus | 32.28 | 4e-15 | 73.2 |
| LLPS-Ran-3978 | Rattus norvegicus | 32.28 | 3e-15 | 73.2 |
| LLPS-Fec-2050 | Felis catus | 32.28 | 8e-15 | 72.4 |
| LLPS-Urm-2534 | Ursus maritimus | 32.28 | 6e-15 | 72.4 |
| LLPS-Caf-1693 | Canis familiaris | 32.28 | 2e-14 | 71.2 |
| LLPS-Pof-3886 | Poecilia formosa | 32.23 | 6e-14 | 69.7 |
| LLPS-Cea-2276 | Cercocebus atys | 32.2 | 6e-15 | 72.4 |
| LLPS-Mum-3170 | Mus musculus | 32.2 | 6e-15 | 72.4 |
| LLPS-Maf-2043 | Macaca fascicularis | 32.2 | 6e-15 | 72.4 |
| LLPS-Caj-2536 | Callithrix jacchus | 32.2 | 6e-15 | 72.4 |
| LLPS-Fud-2385 | Fukomys damarensis | 32.2 | 6e-15 | 72.4 |
| LLPS-Gog-2352 | Gorilla gorilla | 32.2 | 6e-15 | 72.4 |
| LLPS-Dio-0201 | Dipodomys ordii | 32.2 | 6e-15 | 72.4 |
| LLPS-Mal-0542 | Mandrillus leucophaeus | 32.2 | 6e-15 | 72.4 |
| LLPS-Paa-0102 | Papio anubis | 32.2 | 6e-15 | 72.4 |
| LLPS-Man-1089 | Macaca nemestrina | 32.2 | 6e-15 | 72.4 |
| LLPS-Scm-2672 | Scophthalmus maximus | 32.2 | 2e-15 | 73.9 |
| LLPS-Pap-3925 | Pan paniscus | 32.2 | 6e-15 | 72.4 |
| LLPS-Pat-1161 | Pan troglodytes | 32.2 | 6e-15 | 72.4 |
| LLPS-Hos-1360 | Homo sapiens | 32.2 | 6e-15 | 72.4 |
| LLPS-Rhb-0656 | Rhinopithecus bieti | 32.2 | 6e-15 | 72.4 |
| LLPS-Orc-1468 | Oryctolagus cuniculus | 32.2 | 1e-14 | 72.0 |
| LLPS-Otg-0720 | Otolemur garnettii | 32.2 | 6e-15 | 72.4 |
| LLPS-Mam-0455 | Macaca mulatta | 32.2 | 6e-15 | 72.4 |
| LLPS-Cap-2449 | Cavia porcellus | 32.2 | 6e-15 | 72.4 |
| LLPS-Poa-3465 | Pongo abelii | 32.2 | 6e-15 | 72.4 |
| LLPS-Ict-2342 | Ictidomys tridecemlineatus | 32.2 | 6e-15 | 72.4 |
| LLPS-Nol-1633 | Nomascus leucogenys | 32.2 | 6e-15 | 72.4 |
| LLPS-Cas-0358 | Carlito syrichta | 32.2 | 4e-15 | 73.2 |
| LLPS-Icp-3484 | Ictalurus punctatus | 31.93 | 3e-15 | 73.6 |
| LLPS-Spr-0120 | Sporisorium reilianum | 31.86 | 7e-12 | 63.9 |
| LLPS-Nec-1212 | Neurospora crassa | 31.71 | 5e-11 | 61.2 |
| LLPS-Php-1486 | Physcomitrella patens | 31.67 | 2e-09 | 57.0 |
| LLPS-Anp-2135 | Anas platyrhynchos | 31.62 | 4e-15 | 73.2 |
| LLPS-Mea-4043 | Mesocricetus auratus | 31.5 | 8e-15 | 72.4 |
| LLPS-Mup-0257 | Mustela putorius furo | 31.5 | 2e-14 | 71.2 |
| LLPS-Aim-4252 | Ailuropoda melanoleuca | 31.5 | 9e-14 | 69.3 |
| LLPS-Bot-1594 | Bos taurus | 31.45 | 5e-12 | 64.3 |
| LLPS-Lac-1886 | Latimeria chalumnae | 31.45 | 2e-14 | 70.9 |
| LLPS-Via-2248 | Vigna angularis | 31.4 | 8e-13 | 66.6 |
| LLPS-Vir-1806 | Vigna radiata | 31.4 | 8e-13 | 66.6 |
| LLPS-Tut-0664 | Tursiops truncatus | 31.36 | 1e-14 | 71.6 |
| LLPS-Gaga-1192 | Gallus gallus | 31.36 | 1e-15 | 74.7 |
| LLPS-Asf-0360 | Aspergillus flavus | 31.25 | 8e-07 | 49.7 |
| LLPS-Asg-0279 | Ashbya gossypii | 30.97 | 3e-10 | 58.9 |
| LLPS-Eqc-3101 | Equus caballus | 30.71 | 1e-09 | 57.4 |
| LLPS-Tum-0057 | Tuber melanosporum | 30.56 | 2e-09 | 57.0 |
| LLPS-Nef-0405 | Neosartorya fischeri | 30.08 | 6e-08 | 52.8 |
| LLPS-Orl-1575 | Oryzias latipes | 29.91 | 5e-13 | 67.0 |
| LLPS-Map-0482 | Magnaporthe poae | 29.87 | 4e-10 | 58.5 |
| LLPS-Miv-0807 | Microbotryum violaceum | 29.82 | 4e-08 | 53.1 |
| LLPS-Asc-0021 | Aspergillus clavatus | 29.81 | 3e-07 | 50.8 |
| LLPS-Sem-0722 | Selaginella moellendorffii | 29.75 | 1e-11 | 63.2 |
| LLPS-Lem-1449 | Leptosphaeria maculans | 29.75 | 1e-12 | 66.2 |
| LLPS-Chr-1652 | Chlamydomonas reinhardtii | 29.69 | 3e-11 | 61.6 |
| LLPS-Coo-0618 | Colletotrichum orbiculare | 29.25 | 1e-08 | 54.3 |
| LLPS-Phn-1158 | Phaeosphaeria nodorum | 29.23 | 2e-09 | 57.0 |
| LLPS-Fus-1111 | Fusarium solani | 28.93 | 2e-10 | 59.7 |
| LLPS-Cogr-0375 | Colletotrichum graminicola | 28.93 | 8e-12 | 63.5 |
| LLPS-Dos-0719 | Dothistroma septosporum | 28.75 | 2e-07 | 51.2 |
| LLPS-Gag-0454 | Gaeumannomyces graminis | 28.57 | 2e-09 | 56.6 |
| LLPS-Pyt-1566 | Pyrenophora teres | 28.57 | 4e-11 | 61.6 |
| LLPS-Pytr-1001 | Pyrenophora triticirepentis | 27.78 | 9e-11 | 60.8 |
| LLPS-Cus-1300 | Cucumis sativus | 27.64 | 7e-10 | 58.2 |
| LLPS-Kop-0200 | Komagataella pastoris | 27.27 | 5e-10 | 58.5 |
| LLPS-Trr-0406 | Trichoderma reesei | 27.1 | 4e-07 | 50.1 |
| LLPS-Fuo-0146 | Fusarium oxysporum | 26.83 | 2e-09 | 56.6 |
| LLPS-Asn-1262 | Aspergillus nidulans | 26.61 | 2e-08 | 53.9 |
| LLPS-Put-0348 | Puccinia triticina | 26.23 | 6e-11 | 61.2 |
| LLPS-Yal-0833 | Yarrowia lipolytica | 26.19 | 2e-08 | 53.9 |
| LLPS-Trv-0011 | Trichoderma virens | 26.19 | 1e-10 | 60.1 |
| LLPS-Crn-0455 | Cryptococcus neoformans | 26.17 | 4e-10 | 58.5 |
| LLPS-Pug-0644 | Puccinia graminis | 25.86 | 7e-09 | 55.1 |
| LLPS-Blg-1277 | Blumeria graminis | 25.62 | 1e-07 | 51.6 |
| LLPS-Beb-1161 | Beauveria bassiana | 25.62 | 3e-09 | 56.2 |
| LLPS-Asni-0134 | Aspergillus niger | 25.6 | 5e-08 | 53.1 |
| LLPS-Mel-0953 | Melampsora laricipopulina | 24.37 | 5e-09 | 55.8 |