LLPS-Cae-0343
mex-1
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | MEX-1 |
| Gene Name: | mex-1, CELE_W03C9.7, W03C9.7 |
| Ensembl Gene: | WBGene00003228 |
| Ensembl Protein: | W03C9.7a.3 |
| Organism: | Caenorhabditis elegans |
| Taxa ID: | 6239 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| P granule | "...A current list of P granule components is shown in the Table." | Caenorhabditis elegans | 19875490 |
| P granule | "...14 P-granule components were used for this study: four were constitutive P-granule components—PGL-1, PGL-3, GLH-1, and GLH-3 —and ten were transient components: MEX-1, MEX-3, POS-1, OMA-1, OMA-2, SPN-4, GLD-1, GLD-3, CGH-1, and IFE-1." | N/A | 21402787 |
| P-body, Others | Predicted from orthologs | N/A | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | W03C9.7a.3 | W03C9.7a.3 |
| Ensembl | W03C9.7a.2 | W03C9.7a.2 |
| Ensembl | W03C9.7a.4 | W03C9.7a.4 |
| Ensembl | W03C9.7b.1 | W03C9.7b.1 |
| Ensembl | W03C9.7b.2 | W03C9.7b.2 |
| Ensembl | W03C9.7a.1 | W03C9.7a.1 |
| Ensembl | W03C9.7b.3 | W03C9.7b.3 |
| UniProt | G5ECB9, G5ECB9_CAEEL | |
| GeneBank | BX284602, U81043 | AAC47486.1, CAA91362.2 |
| RefSeq | NM_001267396.1 | NP_001254325.1 |
| Entrez | 174836 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQSSNGEHHQ QKQTPYFMNA PCDPALLALA QQTFLGFQPQ KNMYQHGFPP MLPHRNLIPS 60 61 LAAAIPEMDK LMLEEPIEAG SMPYRRATNK NISVSDDSFN NMHRSSSSSQ YRRHSAQWET 120 121 MTDDERESVQ RQKRKEEAFK TALCDAFKRS GSCPYGEACR FAHGENELRM PSQPRGKAHP 180 181 KYKTQLCDKF SNFGQCPYGP RCQFIHKLKK GLPLSEYNRA LQEGEISPAR DDEITNPDES 240 241 SSQVEDLSEL HHRQHQQQQQ YQQRYRRPPF NNFHDMSDSG YSAPRRRLHH QFEHLGSEQQ 300 301 QQQQQQTPAP KIVYPSMQVV NIEMATGDGP KRSDNHHYHH HHHQRRHIPA PPSTGPLSSL 360 361 IDQADYEASM ASGKMFGKPE NIRTYGAMIR ANEEHVERNQ TGVVKKERAT VLPKRDLSLI 420 421 REEDTLLVDG SHLNMTSSAI LPAHQIPSTT TTSTSSPVQE QPWYEKIFGK MTMIQEESSM 480 481 GGEDDDAHED HYSR 494 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGGATA GTGGATACAG TGCTCCTCGC CGCCGGCTTC ATCATCAATT CGAGCATCTT 60 61 GGTAGTGAGC AGCAGCAGCA GCAGCAGCAG CAGACACCAG CTCCGAAGAT TGTCTATCCA 120 121 TCGATGCAAG TTGTCAATAT TGAAATGGCA ACTGGTGACG GACCTAAAAG GTCTGACAAT 180 181 CATCATTATC ATCATCATCA TCATCAACGT CGTCATATTC CGGCACCACC ATCCACCGGT 240 241 CCACTGAGCT CTCTCATTGA TCAGGCCGAC TATGAAGCTT CTATGGCAAG CGGGAAAATG 300 301 TTCGGAAAAC CAGAGAACAT TCGCACCTAT GGAGCCATGA TCCGCGCCAA CGAGGAGCAC 360 361 GTCGAGCGTA ATCAGACTGG AGTTGTCAAG AAGGAACGGG CGACGGTTCT ACCGAAAAGG 420 421 GATCTTTCAC TGATTCGCGA GGAGGATACA CTGCTCGTCG ACGGTTCTCA TCTGAATATG 480 481 ACGTCATCGG CGATTCTGCC AGCTCATCAA ATCCCTTCCA CCACGACCAC CAGCACATCA 540 541 TCTCCAGTCC AAGAACAGCC GTGGTACGAG AAGATTTTCG GGAAAATGAC AATGATCCAA 600 601 GAGGAATCAT CGATGGGCGG TGAAGACGAC GATGCTCACG AAGATCATTA TTCGAGATAA 660 |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Drug | ||||
| CTD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| ENPD | ||||
| Element | ||||
| RAID | microRNA.org | |||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Maf-4783 | Macaca fascicularis | 57.35 | 9e-17 | 87.0 |
| LLPS-Mum-4854 | Mus musculus | 57.35 | 1e-16 | 86.7 |
| LLPS-Chs-3838 | Chlorocebus sabaeus | 57.35 | 9e-17 | 87.0 |
| LLPS-Sus-4485 | Sus scrofa | 57.35 | 1e-16 | 86.7 |
| LLPS-Aon-4835 | Aotus nancymaae | 57.35 | 2e-16 | 85.9 |
| LLPS-Cea-0722 | Cercocebus atys | 57.35 | 9e-17 | 87.0 |
| LLPS-Caj-2972 | Callithrix jacchus | 57.35 | 2e-16 | 85.9 |
| LLPS-Tut-2354 | Tursiops truncatus | 57.35 | 2e-16 | 85.9 |
| LLPS-Bot-2078 | Bos taurus | 57.35 | 1e-16 | 86.7 |
| LLPS-Ran-4885 | Rattus norvegicus | 57.35 | 2e-16 | 86.3 |
| LLPS-Paa-0755 | Papio anubis | 57.35 | 9e-17 | 87.0 |
| LLPS-Mup-3710 | Mustela putorius furo | 57.35 | 9e-17 | 87.0 |
| LLPS-Hos-2863 | Homo sapiens | 57.35 | 1e-16 | 86.3 |
| LLPS-Pat-2843 | Pan troglodytes | 57.35 | 1e-16 | 86.3 |
| LLPS-Mod-2046 | Monodelphis domestica | 57.35 | 2e-17 | 88.6 |
| LLPS-Fec-2792 | Felis catus | 57.35 | 9e-17 | 87.0 |
| LLPS-Man-1958 | Macaca nemestrina | 57.35 | 9e-17 | 87.0 |
| LLPS-Loa-1526 | Loxodonta africana | 57.35 | 4e-17 | 88.2 |
| LLPS-Otg-4463 | Otolemur garnettii | 57.35 | 1e-16 | 87.0 |
| LLPS-Orc-2884 | Oryctolagus cuniculus | 57.35 | 3e-17 | 87.0 |
| LLPS-Rhb-2336 | Rhinopithecus bieti | 57.35 | 9e-17 | 87.0 |
| LLPS-Poa-1249 | Pongo abelii | 57.35 | 1e-16 | 84.7 |
| LLPS-Caf-2350 | Canis familiaris | 57.35 | 7e-17 | 87.4 |
| LLPS-Eqc-2255 | Equus caballus | 57.35 | 9e-17 | 87.0 |
| LLPS-Mam-2646 | Macaca mulatta | 57.35 | 1e-16 | 86.7 |
| LLPS-Gaga-2556 | Gallus gallus | 57.35 | 6e-17 | 87.4 |
| LLPS-Ict-2680 | Ictidomys tridecemlineatus | 57.35 | 2e-16 | 85.9 |
| LLPS-Nol-1217 | Nomascus leucogenys | 56.52 | 1e-14 | 80.5 |
| LLPS-Dio-2889 | Dipodomys ordii | 56.06 | 2e-15 | 80.9 |
| LLPS-Gog-2382 | Gorilla gorilla | 55.88 | 2e-15 | 81.3 |
| LLPS-Pap-4464 | Pan paniscus | 55.88 | 2e-15 | 81.3 |
| LLPS-Cap-3602 | Cavia porcellus | 55.88 | 1e-16 | 86.3 |
| LLPS-Hov-1825 | Hordeum vulgare | 48.57 | 4e-14 | 77.8 |
| LLPS-Brd-2108 | Brachypodium distachyon | 48.57 | 7e-14 | 77.4 |
| LLPS-Myl-3904 | Myotis lucifugus | 47.46 | 7e-07 | 55.5 |
| LLPS-Via-1307 | Vigna angularis | 47.14 | 4e-13 | 74.7 |
| LLPS-Viv-2279 | Vitis vinifera | 47.14 | 3e-14 | 72.8 |
| LLPS-Phv-0401 | Phaseolus vulgaris | 47.14 | 4e-13 | 74.7 |
| LLPS-Kop-0365 | Komagataella pastoris | 45.59 | 3e-13 | 73.6 |
| LLPS-Tar-3996 | Takifugu rubripes | 44.55 | 5e-19 | 93.6 |
| LLPS-Mea-1701 | Mesocricetus auratus | 44.44 | 2e-15 | 82.4 |
| LLPS-Anc-2066 | Anolis carolinensis | 43.24 | 2e-17 | 89.0 |
| LLPS-Arl-1291 | Arabidopsis lyrata | 42.53 | 1e-15 | 81.6 |
| LLPS-Sem-2196 | Selaginella moellendorffii | 41.98 | 4e-08 | 57.0 |
| LLPS-Sac-0737 | Saccharomyces cerevisiae | 41.56 | 9e-13 | 72.8 |
| LLPS-Nia-2405 | Nicotiana attenuata | 41.38 | 4e-14 | 77.4 |
| LLPS-Vir-2259 | Vigna radiata | 40.7 | 4e-13 | 71.2 |
| LLPS-Php-2113 | Physcomitrella patens | 39.13 | 3e-06 | 53.5 |
| LLPS-Orm-1494 | Oryza meridionalis | 37.35 | 1e-05 | 52.4 |
| LLPS-Lep-2300 | Leersia perrieri | 37.18 | 2e-06 | 54.3 |
| LLPS-Met-0547 | Medicago truncatula | 36.21 | 1e-13 | 76.3 |
| LLPS-Orb-1151 | Oryza barthii | 35.9 | 7e-06 | 52.8 |
| LLPS-Ori-2377 | Oryza indica | 35.9 | 5e-06 | 53.1 |
| LLPS-Orni-1023 | Oryza nivara | 35.9 | 6e-06 | 52.8 |
| LLPS-Orgl-2165 | Oryza glumaepatula | 35.9 | 6e-06 | 52.8 |
| LLPS-Ors-2243 | Oryza sativa | 35.9 | 5e-06 | 53.1 |
| LLPS-Orp-1029 | Oryza punctata | 35.9 | 5e-06 | 53.1 |
| LLPS-Orr-2203 | Oryza rufipogon | 35.9 | 7e-06 | 52.8 |
| LLPS-Org-1924 | Oryza glaberrima | 35.9 | 5e-06 | 53.1 |
| LLPS-Sei-0771 | Setaria italica | 34.83 | 8e-06 | 51.6 |
| LLPS-Orbr-0244 | Oryza brachyantha | 34.62 | 2e-06 | 54.7 |
| LLPS-Sob-0734 | Sorghum bicolor | 29.84 | 3e-06 | 53.9 |