LLPS-Brr-3013
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SCS-alpha |
| Ensembl Gene: | Bra028665 |
| Ensembl Protein: | Bra028665.1-P |
| Organism: | Brassica rapa |
| Taxa ID: | 51351 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Bra028665.1 | Bra028665.1-P |
| UniProt | M4EIQ0, M4EIQ0_BRARP |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSRQVARLLG SLSRRCSSTS SEAIPPTLSS FTQSRSFASD PPPPAAVFVD KNTRVMCQGI 60 61 TGKNGTFHTE QAIEYGTKMV AGVTPKKGGT EHLGLPVFNS VAEAKAETKA NASVIYVPAP 120 121 FAAAAIMEGI EAELDLIVCI TEGIPQHDMV RVKHALNSQS KTRLIGPNCP GIIKPGECKI 180 181 GIMPGYIHKP GKIGIVSRSG TLTYEAVFQT TAVGLGQSTC VGIGGDPFNG TNFVDCLEKF 240 241 FVDPQTEGIV LIGEIGGTAE EDAAALIKES GTDKPVVAFI AGLTAPPGRR MGHAGAIVSG 300 301 GKGTAQDKIK SLNDAGVKVV ESPAKIGAAM YDLFKERGLL KQ 342 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTAGAC AAGTCGCAAG GCTCCTCGGA TCTCTGTCTC GCCGCTGCTC AAGCACCAGC 60 61 TCCGAAGCTA TTCCTCCGAC TCTCAGCTCG TTCACCCAAT CTCGCTCATT CGCGTCGGAT 120 121 CCTCCCCCTC CAGCCGCCGT CTTCGTCGAC AAAAACACCA GAGTCATGTG CCAAGGGATC 180 181 ACCGGAAAGA ACGGGACTTT CCACACCGAG CAAGCCATTG AGTACGGCAC CAAAATGGTG 240 241 GCAGGAGTGA CGCCAAAGAA GGGAGGAACG GAGCACTTAG GCCTCCCTGT GTTCAACTCT 300 301 GTTGCTGAAG CAAAAGCTGA GACCAAAGCC AATGCCTCTG TGATCTATGT TCCCGCGCCT 360 361 TTCGCTGCTG CTGCTATTAT GGAGGGGATA GAAGCTGAGT TGGATCTTAT TGTGTGTATT 420 421 ACTGAAGGAA TCCCTCAGCA TGACATGGTA CGTGTAAAGC ATGCTCTTAA CAGTCAGTCG 480 481 AAAACTAGGC TGATTGGTCC AAACTGCCCT GGGATTATCA AGCCTGGTGA GTGCAAGATT 540 541 GGTATTATGC CGGGGTACAT CCACAAGCCT GGCAAGATTG GGATTGTTTC TCGTTCTGGA 600 601 ACCTTGACAT ATGAAGCTGT TTTCCAAACA ACTGCTGTTG GTCTAGGCCA GTCTACTTGT 660 661 GTAGGAATTG GTGGAGATCC TTTTAACGGT ACCAACTTTG TGGACTGCTT GGAGAAATTC 720 721 TTTGTTGATC CTCAAACTGA AGGTATTGTT CTCATTGGAG AAATTGGAGG CACTGCAGAA 780 781 GAAGATGCTG CAGCTTTGAT AAAGGAAAGT GGTACTGATA AACCTGTTGT TGCTTTCATT 840 841 GCTGGGCTTA CTGCACCACC GGGTCGTCGA ATGGGTCATG CAGGAGCCAT TGTTTCTGGT 900 901 GGCAAAGGTA CAGCTCAGGA CAAGATTAAG AGCCTAAATG ATGCAGGAGT GAAGGTTGTT 960 961 GAATCCCCAG CTAAGATAGG AGCGGCCATG TATGATCTCT TTAAAGAAAG AGGTCTTTTG 1020 1021 AAGCAGTGA 1029 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrion | |
Molecular Function | Cofactor binding | |
Molecular Function | Nucleotide binding | |
Molecular Function | Succinate-CoA ligase (ADP-forming) activity | |
Biological Process | Tricarboxylic acid cycle |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Brn-0773 | Brassica napus | 100.0 | 0.0 | 633 |
| LLPS-Bro-2315 | Brassica oleracea | 98.54 | 0.0 | 624 |
| LLPS-Art-0950 | Arabidopsis thaliana | 94.6 | 0.0 | 586 |
| LLPS-Arl-2046 | Arabidopsis lyrata | 92.8 | 0.0 | 598 |
| LLPS-Zem-2512 | Zea mays | 92.2 | 3e-126 | 372 |
| LLPS-Mae-0528 | Manihot esculenta | 90.85 | 0.0 | 520 |
| LLPS-Pot-1246 | Populus trichocarpa | 90.48 | 0.0 | 527 |
| LLPS-Coc-1141 | Corchorus capsularis | 90.13 | 0.0 | 537 |
| LLPS-Thc-1886 | Theobroma cacao | 90.0 | 5e-178 | 505 |
| LLPS-Tra-2926 | Triticum aestivum | 89.83 | 0.0 | 526 |
| LLPS-Orbr-2129 | Oryza brachyantha | 89.69 | 6e-160 | 456 |
| LLPS-Sot-1845 | Solanum tuberosum | 89.52 | 0.0 | 544 |
| LLPS-Cus-0124 | Cucumis sativus | 89.32 | 0.0 | 545 |
| LLPS-Ori-2444 | Oryza indica | 89.31 | 1e-157 | 456 |
| LLPS-Orp-0245 | Oryza punctata | 89.26 | 0.0 | 522 |
| LLPS-Mua-0811 | Musa acuminata | 89.18 | 3e-174 | 495 |
| LLPS-Nia-0275 | Nicotiana attenuata | 89.03 | 0.0 | 536 |
| LLPS-Orni-1979 | Oryza nivara | 88.96 | 0.0 | 523 |
| LLPS-Orgl-1005 | Oryza glumaepatula | 88.96 | 0.0 | 523 |
| LLPS-Ors-0415 | Oryza sativa | 88.96 | 0.0 | 523 |
| LLPS-Orm-1100 | Oryza meridionalis | 88.96 | 0.0 | 523 |
| LLPS-Orr-2381 | Oryza rufipogon | 88.96 | 0.0 | 523 |
| LLPS-Org-0568 | Oryza glaberrima | 88.96 | 0.0 | 522 |
| LLPS-Sol-0701 | Solanum lycopersicum | 88.89 | 0.0 | 541 |
| LLPS-Hea-1220 | Helianthus annuus | 88.82 | 0.0 | 531 |
| LLPS-Orb-2216 | Oryza barthii | 88.63 | 0.0 | 521 |
| LLPS-Sei-0270 | Setaria italica | 88.63 | 0.0 | 521 |
| LLPS-Gor-0811 | Gossypium raimondii | 88.54 | 0.0 | 524 |
| LLPS-Met-2057 | Medicago truncatula | 88.27 | 2e-180 | 509 |
| LLPS-Sob-1727 | Sorghum bicolor | 87.96 | 0.0 | 520 |
| LLPS-Viv-2366 | Vitis vinifera | 87.3 | 4e-178 | 504 |
| LLPS-Prp-1375 | Prunus persica | 87.03 | 4e-179 | 507 |
| LLPS-Brd-2247 | Brachypodium distachyon | 86.26 | 0.0 | 531 |
| LLPS-Lep-2021 | Leersia perrieri | 85.99 | 0.0 | 521 |
| LLPS-Dac-1832 | Daucus carota | 85.9 | 0.0 | 527 |
| LLPS-Via-2182 | Vigna angularis | 85.49 | 9e-180 | 508 |
| LLPS-Vir-1085 | Vigna radiata | 85.49 | 7e-180 | 508 |
| LLPS-Glm-2693 | Glycine max | 85.23 | 1e-179 | 508 |
| LLPS-Phv-1302 | Phaseolus vulgaris | 85.19 | 7e-180 | 508 |
| LLPS-Sem-1370 | Selaginella moellendorffii | 83.47 | 2e-55 | 184 |
| LLPS-Php-0845 | Physcomitrella patens | 83.33 | 2e-177 | 502 |
| LLPS-Amt-1776 | Amborella trichopoda | 80.77 | 5e-163 | 465 |
| LLPS-Chr-0755 | Chlamydomonas reinhardtii | 79.02 | 4e-159 | 456 |
| LLPS-Osl-1200 | Ostreococcus lucimarinus | 76.43 | 9e-160 | 458 |
| LLPS-Tru-1736 | Triticum urartu | 76.15 | 5e-176 | 501 |
| LLPS-Cis-0254 | Ciona savignyi | 73.76 | 5e-129 | 379 |
| LLPS-Pes-0276 | Pelodiscus sinensis | 72.38 | 2e-86 | 266 |
| LLPS-Ran-0431 | Rattus norvegicus | 71.72 | 3e-131 | 386 |
| LLPS-Caf-0254 | Canis familiaris | 71.72 | 1e-120 | 359 |
| LLPS-Aim-1993 | Ailuropoda melanoleuca | 71.38 | 1e-125 | 371 |
| LLPS-Tag-3219 | Taeniopygia guttata | 71.38 | 4e-128 | 377 |
| LLPS-Leo-1460 | Lepisosteus oculatus | 71.04 | 5e-125 | 369 |
| LLPS-Myl-1927 | Myotis lucifugus | 71.04 | 2e-121 | 360 |
| LLPS-Anp-2462 | Anas platyrhynchos | 71.04 | 3e-127 | 375 |
| LLPS-Urm-1461 | Ursus maritimus | 71.04 | 4e-125 | 370 |
| LLPS-Fia-1629 | Ficedula albicollis | 71.04 | 5e-128 | 378 |
| LLPS-Sah-1397 | Sarcophilus harrisii | 70.71 | 5e-121 | 360 |
| LLPS-Fud-0495 | Fukomys damarensis | 70.71 | 1e-120 | 359 |
| LLPS-Mup-1225 | Mustela putorius furo | 70.71 | 8e-125 | 370 |
| LLPS-Meg-2437 | Meleagris gallopavo | 70.71 | 7e-127 | 374 |
| LLPS-Fec-3490 | Felis catus | 70.71 | 1e-120 | 358 |
| LLPS-Ova-1895 | Ovis aries | 70.37 | 1e-118 | 353 |
| LLPS-Orn-0598 | Oreochromis niloticus | 70.37 | 1e-124 | 368 |
| LLPS-Gaga-1334 | Gallus gallus | 70.37 | 2e-126 | 372 |
| LLPS-Asm-1124 | Astyanax mexicanus | 70.34 | 7e-119 | 354 |
| LLPS-Xim-0026 | Xiphophorus maculatus | 70.03 | 3e-123 | 364 |
| LLPS-Cii-0537 | Ciona intestinalis | 70.0 | 1e-128 | 379 |
| LLPS-Drm-1175 | Drosophila melanogaster | 69.93 | 8e-128 | 376 |
| LLPS-Orl-1683 | Oryzias latipes | 69.7 | 8e-123 | 363 |
| LLPS-Pof-2614 | Poecilia formosa | 69.7 | 2e-121 | 360 |
| LLPS-Anc-3286 | Anolis carolinensis | 69.7 | 8e-122 | 361 |
| LLPS-Tar-0168 | Takifugu rubripes | 69.49 | 7e-122 | 361 |
| LLPS-Icp-2116 | Ictalurus punctatus | 69.46 | 5e-121 | 359 |
| LLPS-Mea-3243 | Mesocricetus auratus | 69.43 | 8e-132 | 387 |
| LLPS-Dar-2967 | Danio rerio | 69.36 | 4e-122 | 362 |
| LLPS-Cap-0577 | Cavia porcellus | 69.36 | 6e-118 | 352 |
| LLPS-Ten-2855 | Tetraodon nigroviridis | 69.15 | 2e-120 | 357 |
| LLPS-Nol-1262 | Nomascus leucogenys | 69.09 | 5e-66 | 214 |
| LLPS-Ora-1828 | Ornithorhynchus anatinus | 68.79 | 2e-128 | 378 |
| LLPS-Orc-1744 | Oryctolagus cuniculus | 68.79 | 2e-120 | 358 |
| LLPS-Poa-0125 | Pongo abelii | 68.79 | 3e-134 | 393 |
| LLPS-Scm-1765 | Scophthalmus maximus | 68.69 | 3e-121 | 359 |
| LLPS-Dio-2627 | Dipodomys ordii | 68.61 | 2e-115 | 345 |
| LLPS-Lac-0965 | Latimeria chalumnae | 68.56 | 7e-118 | 351 |
| LLPS-Caj-4123 | Callithrix jacchus | 68.47 | 1e-124 | 369 |
| LLPS-Gog-0714 | Gorilla gorilla | 68.47 | 1e-124 | 369 |
| LLPS-Ere-0154 | Erinaceus europaeus | 68.47 | 5e-125 | 369 |
| LLPS-Hos-1943 | Homo sapiens | 68.47 | 1e-124 | 369 |
| LLPS-Pap-2673 | Pan paniscus | 68.47 | 2e-124 | 368 |
| LLPS-Pat-3248 | Pan troglodytes | 68.47 | 4e-124 | 367 |
| LLPS-Gaa-1224 | Gasterosteus aculeatus | 68.35 | 8e-121 | 358 |
| LLPS-Mam-1961 | Macaca mulatta | 68.25 | 7e-124 | 367 |
| LLPS-Cea-2016 | Cercocebus atys | 68.15 | 1e-125 | 371 |
| LLPS-Maf-1878 | Macaca fascicularis | 68.15 | 1e-125 | 372 |
| LLPS-Chs-1040 | Chlorocebus sabaeus | 68.15 | 2e-125 | 373 |
| LLPS-Bot-1290 | Bos taurus | 68.15 | 9e-120 | 357 |
| LLPS-Paa-2407 | Papio anubis | 68.15 | 1e-125 | 372 |
| LLPS-Mal-2236 | Mandrillus leucophaeus | 68.15 | 1e-125 | 372 |
| LLPS-Man-1740 | Macaca nemestrina | 68.15 | 5e-126 | 372 |
| LLPS-Ict-1689 | Ictidomys tridecemlineatus | 68.15 | 4e-120 | 357 |
| LLPS-Rhb-0373 | Rhinopithecus bieti | 68.05 | 4e-124 | 367 |
| LLPS-Cae-1305 | Caenorhabditis elegans | 67.94 | 1e-120 | 357 |
| LLPS-Gas-1351 | Galdieria sulphuraria | 67.89 | 2e-125 | 370 |
| LLPS-Mum-4248 | Mus musculus | 67.83 | 2e-126 | 374 |
| LLPS-Tut-1705 | Tursiops truncatus | 67.83 | 2e-118 | 353 |
| LLPS-Eqc-0441 | Equus caballus | 67.72 | 1e-117 | 353 |
| LLPS-Pyt-1169 | Pyrenophora teres | 67.24 | 3e-125 | 370 |
| LLPS-Pytr-0887 | Pyrenophora triticirepentis | 67.24 | 2e-125 | 370 |
| LLPS-Fuv-1116 | Fusarium verticillioides | 67.12 | 4e-123 | 364 |
| LLPS-Fuo-0583 | Fusarium oxysporum | 67.12 | 4e-123 | 364 |
| LLPS-Loa-1115 | Loxodonta africana | 66.98 | 8e-125 | 369 |
| LLPS-Lem-0527 | Leptosphaeria maculans | 66.89 | 9e-125 | 369 |
| LLPS-Chc-0966 | Chondrus crispus | 66.78 | 3e-129 | 379 |
| LLPS-Cogr-1179 | Colletotrichum graminicola | 66.78 | 2e-122 | 363 |
| LLPS-Otg-0504 | Otolemur garnettii | 66.56 | 3e-119 | 355 |
| LLPS-Fus-1409 | Fusarium solani | 66.44 | 7e-122 | 361 |
| LLPS-Dos-1018 | Dothistroma septosporum | 65.77 | 2e-121 | 361 |
| LLPS-Map-0325 | Magnaporthe poae | 65.76 | 8e-121 | 358 |
| LLPS-Trv-1453 | Trichoderma virens | 65.76 | 1e-120 | 358 |
| LLPS-Cym-1011 | Cyanidioschyzon merolae | 65.42 | 5e-125 | 370 |
| LLPS-Asfu-1548 | Aspergillus fumigatus | 65.19 | 2e-116 | 347 |
| LLPS-Beb-0475 | Beauveria bassiana | 65.08 | 1e-114 | 343 |
| LLPS-Asc-1086 | Aspergillus clavatus | 64.85 | 3e-116 | 347 |
| LLPS-Asn-1067 | Aspergillus nidulans | 64.85 | 1e-117 | 350 |
| LLPS-Nef-1071 | Neosartorya fischeri | 64.85 | 9e-117 | 348 |
| LLPS-Scc-0857 | Schizosaccharomyces cryophilus | 64.83 | 3e-117 | 349 |
| LLPS-Scs-0349 | Sclerotinia sclerotiorum | 64.51 | 3e-115 | 344 |
| LLPS-Zyt-0737 | Zymoseptoria tritici | 64.43 | 3e-119 | 355 |
| LLPS-Gag-0622 | Gaeumannomyces graminis | 63.9 | 2e-121 | 360 |
| LLPS-Miv-0652 | Microbotryum violaceum | 63.73 | 8e-119 | 353 |
| LLPS-Coo-0784 | Colletotrichum orbiculare | 63.55 | 6e-125 | 369 |
| LLPS-Nec-0253 | Neurospora crassa | 63.26 | 6e-121 | 359 |
| LLPS-Sus-0504 | Sus scrofa | 62.97 | 3e-100 | 307 |
| LLPS-Yal-0639 | Yarrowia lipolytica | 62.97 | 9e-113 | 338 |
| LLPS-Spr-0558 | Sporisorium reilianum | 62.89 | 3e-118 | 352 |
| LLPS-Usm-1078 | Ustilago maydis | 62.89 | 9e-118 | 351 |
| LLPS-Crn-0204 | Cryptococcus neoformans | 62.84 | 6e-119 | 354 |
| LLPS-Phn-1124 | Phaeosphaeria nodorum | 62.73 | 3e-124 | 367 |
| LLPS-Scf-1751 | Scleropages formosus | 62.5 | 2e-117 | 350 |
| LLPS-Mel-0351 | Melampsora laricipopulina | 62.42 | 5e-120 | 357 |
| LLPS-Put-0613 | Puccinia triticina | 62.42 | 1e-119 | 356 |
| LLPS-Ved-1135 | Verticillium dahliae | 62.39 | 2e-123 | 365 |
| LLPS-Tum-0304 | Tuber melanosporum | 62.37 | 6e-117 | 348 |
| LLPS-Ast-0656 | Aspergillus terreus | 62.3 | 2e-118 | 352 |
| LLPS-Mao-0330 | Magnaporthe oryzae | 62.1 | 7e-118 | 351 |
| LLPS-Aso-0216 | Aspergillus oryzae | 61.86 | 9e-117 | 348 |
| LLPS-Asf-0614 | Aspergillus flavus | 61.86 | 9e-117 | 348 |
| LLPS-Kop-1482 | Komagataella pastoris | 61.82 | 2e-106 | 322 |
| LLPS-Asni-0554 | Aspergillus niger | 61.59 | 6e-118 | 351 |
| LLPS-Trr-0044 | Trichoderma reesei | 61.4 | 2e-121 | 360 |
| LLPS-Scj-0178 | Schizosaccharomyces japonicus | 61.18 | 1e-119 | 355 |
| LLPS-Scp-1446 | Schizosaccharomyces pombe | 61.04 | 7e-113 | 338 |
| LLPS-Blg-0883 | Blumeria graminis | 60.71 | 4e-114 | 343 |
| LLPS-Mod-0753 | Monodelphis domestica | 59.75 | 3e-99 | 304 |
| LLPS-Cog-1383 | Colletotrichum gloeosporioides | 59.66 | 2e-97 | 298 |
| LLPS-Pug-1408 | Puccinia graminis | 58.9 | 9e-121 | 359 |
| LLPS-Aon-2154 | Aotus nancymaae | 58.44 | 1e-72 | 231 |
| LLPS-Abg-0959 | Absidia glauca | 57.59 | 9e-62 | 203 |
| LLPS-Asg-0189 | Ashbya gossypii | 56.42 | 1e-93 | 288 |
| LLPS-Hov-0283 | Hordeum vulgare | 30.84 | 1e-19 | 93.6 |