LLPS-Bot-4713
WAPL
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | WAPL cohesin release factor |
| Gene Name: | WAPL |
| Ensembl Gene: | ENSBTAG00000012213.6 |
| Ensembl Protein: | ENSBTAP00000072396.1 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| PcG body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000066703.1 | ENSBTAP00000072396.1 |
| Ensembl | ENSBTAT00000016211.6 | ENSBTAP00000016211.5 |
| UniProt | E1BGC3, E1BGC3_BOVIN | |
| RefSeq | XM_001789058.6, XM_002698897.5, XM_005193121.3, XM_005226523.3 | XP_001789110.3, XP_002698943.2, XP_005193178.1, XP_005226580.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTSRFGKTYS RKGGNGSSKF DEVFSNKRTT LSTKWGETTF MAKLGQKRPN FKPDIQEVPK 60 61 KPKIEEENTG DPFGFDSDDE SLPVSSKNLA KGSSYTESSE AAQLEEVTSV LEANSKISHV 120 121 MGEDSVVSDK CLRLEDTLLG KEKSTNRVLE DDASRSSCAK LMTSDKVENF SEEHEKNSHH 180 181 IYKNAEDSTK KHNAETTVAS GYKADEIKEN DTWNSQLGKR SESPSETSSI KGSVRTGLYE 240 241 WDNDFEDSRS EDCILNLDSD PLLEMKDEDF KNRLENLNEA IEEDMMQSVL RPSNCRTYCR 300 301 ANKAKSSQGA SSFDKLMDGT SQALAKANSE SSKDGLNQAK KGSVSCGTSF RGTVGRTRDY 360 361 TVLHPSCLSV CNVTIQDTME RSMDEFTAST PADLGEAGRL RKKADIATSK TTTRFRPSNT 420 421 KSKKDVKLEF FGFEDHDETG GDEGGSGSSN YKIKYFGFDD LSESEDDEDD DCQVERKTSK 480 481 KRTKTAPSPS LQPPPESNDN SQDSQSSSNN AENLDFTEDL PGVPESVKKP PNKQGDKSKE 540 541 NTRKIFSGPK RSPTKAVYNA RHWNHPDSEE LPAPPVVKPQ SVTVRLSSKE QNQKDDGVFK 600 601 APAPPPKVIK TVTIPTQPYQ DIVTALKCRK EDKELYTVVQ HVKHFNDVVE FGENQEFTDD 660 661 IEYLLSGLKS TQPLNTRCLS VISLATKCAM PSFRMHLRAH GMVAMVFKTL DDSQHHQNLS 720 721 LCTAALMYIL SRDRLNMDLD RASLDLMIRL LELEQDASSA KLLNEKDMNK IKEKIRRLCE 780 781 TVHNKHLDLE NITTGHLAME TLLSLTSKRA GDWFKEELRL LGGLDHIVDK VKECVDHLSK 840 841 DEDEEKLVAS LWGAERCLRV LESVTVHNPE NQSYLIAYKD SQLIVSSAKA LQHCEELIKQ 900 901 YNRAENSICL PDSKPLPQQN VTNHVGKAVE DCMRAIIGVL LNLTNDNEWG STKTGEQDGL 960 961 IGTAMNCVLQ VPKYLPQEQR FDIRVLGLGL LINLVEYSAR NRHCLVNMET SCSFDSSFCS 1020 1021 GEGDDSLRIA GQVHAVQALV QLFLERERAA QLAESKTDEL IKDAPTTQHD KSGEWQETSG 1080 1081 EIQWVSTEKA DGAEEKNKKE EDDEELDLNK ALQHAGKHME DCIVASYTAL LLGCLCQESP 1140 1141 INVTTVREYL PEGDFSIMTE MLKKFLSFMN LTCAVGTTGQ KSISRVIEYL EHC 1193 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACATCCA GATTTGGGAA AACATACAGT AGGAAAGGAG GAAATGGAAG TTCAAAGTTT 60 61 GATGAAGTCT TTTCCAACAA ACGGACCACC CTTAGCACAA AGTGGGGAGA AACCACATTT 120 121 ATGGCTAAAT TAGGACAGAA GAGGCCCAAT TTCAAACCAG ATATCCAAGA AGTTCCGAAG 180 181 AAACCTAAGA TAGAAGAAGA AAATACTGGA GATCCTTTTG GATTTGATAG TGATGATGAA 240 241 TCTCTACCAG TTTCTTCAAA GAATTTAGCT AAAGGTTCCT CTTACACGGA ATCTAGTGAA 300 301 GCTGCTCAGT TGGAAGAGGT CACATCTGTA CTTGAAGCTA ATAGCAAAAT TAGTCATGTG 360 361 ATGGGTGAAG ACAGTGTTGT ATCTGATAAA TGCTTACGTT TGGAGGATAC TTTGCTTGGG 420 421 AAAGAAAAGA GCACAAACCG TGTCTTAGAA GATGATGCAA GCAGAAGTAG CTGTGCTAAA 480 481 TTAATGACTT CAGATAAAGT GGAGAACTTT AGTGAAGAAC ATGAAAAGAA TAGTCACCAT 540 541 ATTTACAAAA ATGCTGAAGA CAGTACTAAG AAACACAATG CAGAAACTAC AGTGGCTTCT 600 601 GGATACAAAG CTGATGAAAT CAAGGAAAAT GATACTTGGA ATTCCCAACT TGGGAAAAGG 660 661 TCAGAATCGC CATCAGAAAC ATCATCAATC AAGGGATCTG TAAGAACTGG TTTATATGAA 720 721 TGGGATAATG ATTTTGAAGA TAGCAGATCC GAAGATTGTA TTTTAAATCT GGATAGTGAT 780 781 CCTCTTTTGG AGATGAAGGA TGAGGATTTT AAAAATCGGT TGGAAAATCT AAATGAAGCC 840 841 ATTGAGGAAG ACATGATGCA AAGTGTTCTT AGGCCAAGCA ACTGTAGGAC GTACTGTAGG 900 901 GCCAATAAAG CAAAATCCTC ACAAGGAGCG TCGAGTTTTG ATAAGCTAAT GGACGGCACC 960 961 AGTCAGGCCT TAGCCAAAGC AAACAGTGAA TCTAGTAAAG ATGGCCTGAA TCAGGCAAAG 1020 1021 AAGGGCAGTG TAAGCTGTGG GACCAGTTTT AGAGGGACGG TTGGACGGAC TAGAGATTAT 1080 1081 ACTGTTTTAC ATCCATCTTG CTTGTCAGTT TGTAATGTTA CCATCCAGGA TACTATGGAA 1140 1141 CGCAGCATGG ATGAGTTCAC TGCTTCAACT CCTGCAGATT TGGGAGAAGC TGGCCGGCTA 1200 1201 AGAAAAAAAG CAGATATTGC AACATCTAAG ACCACTACTA GATTTCGACC TAGTAATACT 1260 1261 AAATCTAAAA AGGATGTTAA ACTTGAATTT TTTGGTTTTG AAGATCATGA TGAGACAGGA 1320 1321 GGTGATGAGG GAGGTTCTGG GAGTTCTAAC TACAAAATTA AATATTTTGG CTTTGATGAT 1380 1381 CTCAGTGAAA GTGAAGATGA TGAAGATGAT GACTGTCAGG TGGAAAGAAA GACAAGCAAA 1440 1441 AAAAGAACTA AAACAGCTCC ATCACCCTCC TTGCAGCCTC CTCCAGAAAG CAATGATAAT 1500 1501 TCCCAGGACA GTCAGTCTAG TTCTAATAAT GCAGAAAACT TGGATTTTAC AGAGGACTTG 1560 1561 CCTGGTGTGC CTGAAAGTGT GAAGAAGCCT CCAAATAAAC AAGGAGATAA ATCAAAGGAA 1620 1621 AATACCAGAA AGATTTTTAG TGGCCCCAAA CGGTCTCCTA CAAAAGCCGT ATATAATGCT 1680 1681 AGACATTGGA ATCATCCAGA CTCGGAAGAA CTACCTGCAC CACCAGTAGT AAAACCTCAG 1740 1741 AGTGTCACAG TGAGGCTGTC TTCAAAGGAG CAAAATCAAA AAGATGATGG AGTTTTTAAG 1800 1801 GCTCCTGCAC CACCACCCAA AGTGATAAAA ACTGTGACAA TACCTACTCA GCCCTACCAA 1860 1861 GATATAGTTA CTGCACTGAA ATGCAGAAAA GAAGACAAAG AATTGTATAC TGTTGTTCAG 1920 1921 CACGTGAAGC ACTTCAATGA TGTGGTGGAA TTTGGTGAAA ACCAAGAGTT CACTGATGAC 1980 1981 ATTGAGTACT TGTTAAGTGG CTTAAAGAGC ACACAGCCTC TAAACACACG TTGCCTTAGT 2040 2041 GTTATTAGCT TGGCTACTAA ATGTGCCATG CCCAGTTTTC GAATGCACCT GAGAGCACAT 2100 2101 GGAATGGTAG CAATGGTCTT TAAAACCTTG GATGATTCCC AGCATCATCA GAATCTGTCC 2160 2161 CTTTGTACAG CTGCCCTCAT GTACATTCTG AGTAGAGATC GTTTAAACAT GGATCTTGAT 2220 2221 AGAGCTAGCC TAGATCTGAT GATTCGACTC CTAGAACTGG AACAAGATGC TTCTTCAGCT 2280 2281 AAGCTGCTGA ATGAAAAAGA CATGAACAAA ATCAAAGAAA AAATTCGAAG GCTCTGTGAA 2340 2341 ACTGTACACA ATAAGCACCT TGATCTAGAA AATATAACGA CTGGGCATTT AGCTATGGAG 2400 2401 ACTTTACTGT CCCTTACTTC TAAACGAGCA GGAGACTGGT TTAAAGAAGA ACTACGGCTT 2460 2461 TTGGGTGGTC TGGATCATAT TGTAGATAAA GTGAAAGAAT GTGTGGATCA TTTAAGTAAA 2520 2521 GATGAGGATG AAGAGAAATT AGTAGCCTCA TTATGGGGAG CAGAGAGATG TTTACGAGTT 2580 2581 TTAGAAAGCG TAACAGTGCA TAATCCAGAG AATCAAAGCT ACTTGATTGC CTATAAAGAT 2640 2641 TCACAACTCA TTGTTTCGTC AGCTAAGGCA TTACAACATT GTGAAGAGCT GATTAAGCAG 2700 2701 TATAACCGTG CTGAGAACAG TATATGCTTA CCTGACAGTA AGCCTCTGCC TCAGCAGAAT 2760 2761 GTAACTAACC ACGTGGGCAA AGCAGTGGAG GACTGCATGA GGGCCATCAT TGGGGTGCTG 2820 2821 CTCAACTTAA CTAATGATAA TGAATGGGGC AGCACCAAAA CAGGAGAGCA GGATGGCTTG 2880 2881 ATTGGCACAG CCATGAATTG TGTGCTTCAG GTTCCAAAGT ACCTACCTCA GGAGCAGAGA 2940 2941 TTTGATATTC GAGTGCTGGG TTTAGGTCTA CTGATAAATC TAGTGGAATA TAGTGCTCGA 3000 3001 AATCGGCACT GTCTTGTCAA CATGGAAACA TCATGTTCTT TTGATTCTTC CTTCTGTAGT 3060 3061 GGAGAAGGAG ATGATAGTTT AAGGATAGCT GGACAAGTTC ATGCAGTTCA GGCTTTAGTG 3120 3121 CAGCTGTTCC TTGAGCGAGA GCGAGCAGCA CAGTTGGCAG AAAGTAAAAC AGATGAACTG 3180 3181 ATCAAAGATG CTCCCACCAC TCAGCATGAC AAGAGTGGGG AGTGGCAGGA GACGAGTGGG 3240 3241 GAGATACAGT GGGTGTCAAC TGAGAAGGCT GATGGTGCAG AAGAGAAAAA TAAGAAGGAG 3300 3301 GAGGACGATG AAGAACTTGA CCTCAATAAA GCCCTTCAGC ATGCTGGCAA GCACATGGAG 3360 3361 GATTGCATTG TGGCCTCATA CACAGCACTG CTTCTTGGGT GTCTCTGCCA GGAGAGTCCA 3420 3421 ATCAATGTGA CCACTGTGCG GGAGTATCTG CCAGAAGGGG ACTTTTCAAT AATGACAGAG 3480 3481 ATGCTCAAAA AATTCCTGAG CTTCATGAAT CTTACCTGTG CTGTTGGAAC CACGGGCCAG 3540 3541 AAGTCCATCT CTAGAGTGAT TGAGTACTTG GAACACTGCT AG 3582 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ova-3403 | Ovis aries | 98.41 | 0.0 | 2246 |
| LLPS-Aim-3928 | Ailuropoda melanoleuca | 98.4 | 7e-169 | 513 |
| LLPS-Ora-3407 | Ornithorhynchus anatinus | 97.31 | 2e-175 | 530 |
| LLPS-Dio-2773 | Dipodomys ordii | 97.2 | 3e-167 | 508 |
| LLPS-Sus-4236 | Sus scrofa | 96.66 | 0.0 | 2181 |
| LLPS-Caf-1434 | Canis familiaris | 96.57 | 0.0 | 2214 |
| LLPS-Fec-0317 | Felis catus | 96.49 | 0.0 | 2199 |
| LLPS-Eqc-2566 | Equus caballus | 96.4 | 0.0 | 2185 |
| LLPS-Urm-1289 | Ursus maritimus | 96.32 | 0.0 | 2231 |
| LLPS-Mup-3360 | Mustela putorius furo | 95.9 | 0.0 | 2187 |
| LLPS-Myl-1560 | Myotis lucifugus | 95.49 | 0.0 | 2177 |
| LLPS-Tut-1834 | Tursiops truncatus | 95.4 | 0.0 | 2134 |
| LLPS-Ict-3720 | Ictidomys tridecemlineatus | 95.32 | 0.0 | 2167 |
| LLPS-Cas-2123 | Carlito syrichta | 95.07 | 0.0 | 2176 |
| LLPS-Loa-2887 | Loxodonta africana | 94.9 | 0.0 | 2143 |
| LLPS-Orc-1903 | Oryctolagus cuniculus | 94.4 | 0.0 | 2163 |
| LLPS-Chs-4312 | Chlorocebus sabaeus | 94.31 | 0.0 | 2165 |
| LLPS-Pat-4045 | Pan troglodytes | 94.23 | 0.0 | 2165 |
| LLPS-Pap-2713 | Pan paniscus | 94.23 | 0.0 | 2165 |
| LLPS-Mam-4612 | Macaca mulatta | 94.23 | 0.0 | 2163 |
| LLPS-Gog-3444 | Gorilla gorilla | 94.23 | 0.0 | 2165 |
| LLPS-Man-0570 | Macaca nemestrina | 94.15 | 0.0 | 2160 |
| LLPS-Hos-3671 | Homo sapiens | 94.15 | 0.0 | 2162 |
| LLPS-Mal-3156 | Mandrillus leucophaeus | 94.15 | 0.0 | 2165 |
| LLPS-Rhb-3204 | Rhinopithecus bieti | 94.06 | 0.0 | 2157 |
| LLPS-Poa-0280 | Pongo abelii | 94.06 | 0.0 | 2158 |
| LLPS-Paa-4367 | Papio anubis | 94.06 | 0.0 | 2163 |
| LLPS-Cea-0548 | Cercocebus atys | 93.98 | 0.0 | 2157 |
| LLPS-Maf-3512 | Macaca fascicularis | 93.65 | 0.0 | 2165 |
| LLPS-Mum-3665 | Mus musculus | 92.83 | 0.0 | 2061 |
| LLPS-Ran-4808 | Rattus norvegicus | 92.74 | 0.0 | 2085 |
| LLPS-Fud-2761 | Fukomys damarensis | 92.55 | 0.0 | 2112 |
| LLPS-Caj-2684 | Callithrix jacchus | 91.3 | 0.0 | 2095 |
| LLPS-Cap-4045 | Cavia porcellus | 90.65 | 0.0 | 2033 |
| LLPS-Nol-3369 | Nomascus leucogenys | 89.67 | 0.0 | 2020 |
| LLPS-Mea-2484 | Mesocricetus auratus | 89.63 | 0.0 | 2028 |
| LLPS-Aon-1971 | Aotus nancymaae | 89.07 | 0.0 | 2025 |
| LLPS-Mod-2361 | Monodelphis domestica | 84.74 | 0.0 | 1912 |
| LLPS-Sah-1999 | Sarcophilus harrisii | 84.5 | 0.0 | 1919 |
| LLPS-Anp-0953 | Anas platyrhynchos | 81.11 | 0.0 | 1865 |
| LLPS-Otg-1434 | Otolemur garnettii | 81.02 | 0.0 | 1813 |
| LLPS-Gaga-2088 | Gallus gallus | 80.37 | 0.0 | 1849 |
| LLPS-Fia-1315 | Ficedula albicollis | 80.2 | 0.0 | 1831 |
| LLPS-Meg-2749 | Meleagris gallopavo | 79.95 | 0.0 | 1843 |
| LLPS-Pes-1291 | Pelodiscus sinensis | 79.93 | 0.0 | 1846 |
| LLPS-Tag-2667 | Taeniopygia guttata | 79.78 | 0.0 | 1837 |
| LLPS-Anc-1977 | Anolis carolinensis | 77.45 | 0.0 | 1758 |
| LLPS-Lac-3976 | Latimeria chalumnae | 70.89 | 0.0 | 1620 |
| LLPS-Xet-0623 | Xenopus tropicalis | 69.91 | 0.0 | 1559 |
| LLPS-Tar-2300 | Takifugu rubripes | 63.17 | 0.0 | 1019 |
| LLPS-Leo-2747 | Lepisosteus oculatus | 62.89 | 0.0 | 1348 |
| LLPS-Orl-0797 | Oryzias latipes | 62.04 | 0.0 | 1012 |
| LLPS-Scf-3495 | Scleropages formosus | 60.91 | 0.0 | 1296 |
| LLPS-Dar-3670 | Danio rerio | 58.93 | 0.0 | 1220 |
| LLPS-Icp-1016 | Ictalurus punctatus | 58.12 | 0.0 | 1176 |
| LLPS-Ten-2471 | Tetraodon nigroviridis | 57.04 | 0.0 | 1148 |
| LLPS-Scm-1633 | Scophthalmus maximus | 54.62 | 0.0 | 1109 |
| LLPS-Pof-4036 | Poecilia formosa | 53.32 | 0.0 | 1068 |
| LLPS-Orn-2547 | Oreochromis niloticus | 53.24 | 0.0 | 1106 |
| LLPS-Gaa-3774 | Gasterosteus aculeatus | 52.38 | 0.0 | 1071 |
| LLPS-Xim-3101 | Xiphophorus maculatus | 51.84 | 0.0 | 1069 |
| LLPS-Asm-3562 | Astyanax mexicanus | 41.49 | 5e-71 | 263 |
| LLPS-Cis-0504 | Ciona savignyi | 36.79 | 7e-38 | 147 |
| LLPS-Drm-0239 | Drosophila melanogaster | 34.77 | 3e-85 | 310 |
| LLPS-Sem-1471 | Selaginella moellendorffii | 31.5 | 1e-16 | 89.7 |
| LLPS-Thc-2197 | Theobroma cacao | 28.03 | 2e-12 | 75.9 |
| LLPS-Cus-0257 | Cucumis sativus | 27.86 | 1e-14 | 83.2 |
| LLPS-Cae-1707 | Caenorhabditis elegans | 27.7 | 5e-50 | 194 |
| LLPS-Pot-2801 | Populus trichocarpa | 25.61 | 9e-11 | 70.9 |
| LLPS-Hea-1567 | Helianthus annuus | 25.6 | 2e-12 | 76.3 |