LLPS-Bot-4134
P2RY12
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Purinergic receptor P2Y, G-protein coupled, 12 |
| Gene Name: | P2RY12 |
| Ensembl Gene: | ENSBTAG00000015837.6 |
| Ensembl Protein: | ENSBTAP00000041984.1 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Cajal body, Nuclear speckle | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000044491.2 | ENSBTAP00000041984.1 |
| Ensembl | ENSBTAT00000064076.2 | ENSBTAP00000055434.1 |
| UniProt | Q0IIL0, Q0IIL0_BOVIN | |
| GeneBank | BC122591 | AAI22592.1 |
| RefSeq | NM_001001174.2, XM_005201788.3, XM_005201789.3, XM_010801476.2 | NP_001001174.2, XP_005201845.1, XP_005201846.1, XP_010799778.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDNLTSVAGN SSQCSRDYKI TQVLFPLLYT VLFFVGLITN SLAMRIFFQI RSKSNFIIFL 60 61 KNTVISDLLM ILTFPFKILS DTKLGTGPLR AFVCQVTSVV FYFTMYISIS FLGLITIDRY 120 121 QKTTRPFKTA NPNNLLGAKI LSVVIWAFMF LISLPNMILT NRRPSDKTVK KCSFLKSEFG 180 181 LVWHEIVNYV CQVIFWINFL IVIVCYTLIT KELYKSYVRT RGAGKVPKKK VNIKVFIIIA 240 241 VFFICFVPFH FARIPYTLSQ TRDVFDCTAE NTLFYVKEST LWLTSLNACL DPFIYFFLCK 300 301 SFKNSLMSML RCSNSTSPPS HDNRKKGQDG SDPSEETPM 339 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGACAACC TCACCTCTGT GGCTGGGAAC AGCAGCCAGT GCAGCAGAGA CTACAAGATT 60 61 ACCCAGGTGC TCTTCCCACT CCTCTACACT GTCCTGTTTT TTGTTGGACT CATCACAAAC 120 121 AGCCTGGCAA TGAGGATTTT CTTTCAAATC CGCAGTAAAT CCAACTTTAT TATTTTCCTT 180 181 AAGAACACAG TCATTTCCGA TCTCCTCATG ATTCTGACTT TTCCATTCAA AATCCTCAGC 240 241 GATACTAAAC TGGGAACAGG ACCTCTAAGG GCCTTTGTGT GCCAAGTGAC CTCCGTCGTG 300 301 TTCTACTTCA CGATGTACAT CAGTATCTCA TTCCTAGGAC TAATAACTAT TGATCGCTAC 360 361 CAGAAGACCA CCAGGCCCTT TAAGACAGCC AATCCCAACA ATCTCTTGGG GGCTAAGATT 420 421 CTCTCGGTTG TCATCTGGGC ATTCATGTTC TTAATCTCCT TGCCTAACAT GATTCTGACC 480 481 AACAGGAGGC CGAGTGACAA GACTGTGAAG AAATGCTCAT TTCTGAAGTC AGAGTTTGGT 540 541 CTGGTTTGGC ATGAAATAGT CAATTATGTC TGTCAAGTCA TTTTCTGGAT TAATTTTCTA 600 601 ATTGTCATCG TATGCTATAC GCTCATTACC AAAGAACTGT ACAAGTCATA TGTGAGAACA 660 661 AGGGGTGCTG GCAAAGTCCC CAAGAAAAAG GTAAACATTA AGGTTTTCAT TATCATTGCT 720 721 GTATTCTTTA TATGTTTTGT TCCATTCCAT TTTGCCCGAA TTCCCTACAC CCTGAGTCAA 780 781 ACCCGGGACG TCTTTGACTG CACTGCTGAG AATACTCTGT TCTACGTGAA AGAGAGCACA 840 841 CTCTGGTTAA CGTCCTTAAA TGCATGCCTG GATCCATTCA TCTACTTTTT CCTTTGCAAA 900 901 TCCTTCAAAA ATTCCTTGAT GAGTATGCTG AGATGTTCCA ATTCTACATC ACCTCCATCC 960 961 CATGACAATC GGAAAAAAGG ACAGGATGGC AGTGACCCAA GTGAAGAGAC ACCAATGTAA 1020 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ova-2745 | Ovis aries | 97.94 | 0.0 | 621 |
| LLPS-Tut-1924 | Tursiops truncatus | 94.1 | 0.0 | 592 |
| LLPS-Sus-3239 | Sus scrofa | 93.77 | 0.0 | 588 |
| LLPS-Fec-1207 | Felis catus | 92.63 | 0.0 | 587 |
| LLPS-Caf-4640 | Canis familiaris | 92.63 | 0.0 | 588 |
| LLPS-Aim-4266 | Ailuropoda melanoleuca | 92.04 | 0.0 | 587 |
| LLPS-Cas-3697 | Carlito syrichta | 91.42 | 0.0 | 582 |
| LLPS-Mup-2255 | Mustela putorius furo | 91.15 | 0.0 | 580 |
| LLPS-Mal-4379 | Mandrillus leucophaeus | 90.56 | 0.0 | 578 |
| LLPS-Paa-4497 | Papio anubis | 90.56 | 0.0 | 578 |
| LLPS-Myl-0733 | Myotis lucifugus | 90.56 | 0.0 | 574 |
| LLPS-Maf-2994 | Macaca fascicularis | 90.27 | 0.0 | 578 |
| LLPS-Chs-3465 | Chlorocebus sabaeus | 90.27 | 0.0 | 578 |
| LLPS-Rhb-1345 | Rhinopithecus bieti | 90.27 | 0.0 | 578 |
| LLPS-Hos-2852 | Homo sapiens | 90.27 | 0.0 | 577 |
| LLPS-Mam-0684 | Macaca mulatta | 90.27 | 0.0 | 578 |
| LLPS-Orc-1146 | Oryctolagus cuniculus | 90.24 | 0.0 | 575 |
| LLPS-Cea-4103 | Cercocebus atys | 89.97 | 0.0 | 573 |
| LLPS-Man-2218 | Macaca nemestrina | 89.97 | 0.0 | 578 |
| LLPS-Poa-3821 | Pongo abelii | 89.97 | 0.0 | 573 |
| LLPS-Urm-3227 | Ursus maritimus | 89.68 | 0.0 | 560 |
| LLPS-Nol-3421 | Nomascus leucogenys | 89.68 | 0.0 | 573 |
| LLPS-Eqc-4174 | Equus caballus | 89.68 | 0.0 | 578 |
| LLPS-Otg-2066 | Otolemur garnettii | 89.09 | 0.0 | 566 |
| LLPS-Loa-0639 | Loxodonta africana | 89.09 | 0.0 | 568 |
| LLPS-Aon-4563 | Aotus nancymaae | 88.79 | 0.0 | 565 |
| LLPS-Mum-4022 | Mus musculus | 88.43 | 0.0 | 547 |
| LLPS-Mea-3527 | Mesocricetus auratus | 87.61 | 0.0 | 550 |
| LLPS-Fud-1705 | Fukomys damarensis | 86.98 | 0.0 | 556 |
| LLPS-Ran-1707 | Rattus norvegicus | 86.94 | 0.0 | 544 |
| LLPS-Dio-1910 | Dipodomys ordii | 85.25 | 0.0 | 537 |
| LLPS-Ict-0869 | Ictidomys tridecemlineatus | 84.32 | 0.0 | 551 |
| LLPS-Mod-4028 | Monodelphis domestica | 83.14 | 0.0 | 526 |
| LLPS-Sah-4061 | Sarcophilus harrisii | 82.84 | 0.0 | 517 |
| LLPS-Ora-3391 | Ornithorhynchus anatinus | 80.88 | 8e-179 | 506 |
| LLPS-Anc-0975 | Anolis carolinensis | 71.84 | 2e-141 | 410 |
| LLPS-Anp-1801 | Anas platyrhynchos | 69.76 | 2e-147 | 427 |
| LLPS-Fia-0666 | Ficedula albicollis | 67.37 | 1e-143 | 417 |
| LLPS-Tag-2477 | Taeniopygia guttata | 64.63 | 8e-123 | 362 |
| LLPS-Xet-1352 | Xenopus tropicalis | 63.64 | 5e-119 | 354 |
| LLPS-Lac-2201 | Latimeria chalumnae | 60.47 | 5e-136 | 397 |
| LLPS-Leo-0828 | Lepisosteus oculatus | 58.18 | 3e-108 | 327 |
| LLPS-Dar-2335 | Danio rerio | 56.81 | 3e-95 | 294 |
| LLPS-Ten-2958 | Tetraodon nigroviridis | 56.23 | 1e-103 | 314 |
| LLPS-Tar-1683 | Takifugu rubripes | 53.38 | 2e-96 | 296 |
| LLPS-Pof-2652 | Poecilia formosa | 53.35 | 3e-99 | 303 |
| LLPS-Icp-3500 | Ictalurus punctatus | 53.2 | 5e-91 | 283 |
| LLPS-Scf-1612 | Scleropages formosus | 52.77 | 6e-90 | 280 |
| LLPS-Asm-2710 | Astyanax mexicanus | 51.26 | 3e-101 | 309 |
| LLPS-Gaa-2472 | Gasterosteus aculeatus | 49.12 | 2e-87 | 274 |
| LLPS-Orn-0951 | Oreochromis niloticus | 48.62 | 4e-96 | 296 |
| LLPS-Scm-2390 | Scophthalmus maximus | 47.74 | 2e-90 | 281 |
| LLPS-Xim-0495 | Xiphophorus maculatus | 46.67 | 2e-94 | 292 |
| LLPS-Orl-3798 | Oryzias latipes | 46.06 | 2e-87 | 274 |
| LLPS-Pes-2689 | Pelodiscus sinensis | 26.57 | 6e-13 | 72.8 |
| LLPS-Gaga-3098 | Gallus gallus | 26.2 | 3e-16 | 82.8 |
| LLPS-Meg-2624 | Meleagris gallopavo | 25.48 | 2e-14 | 77.4 |
| LLPS-Gog-2996 | Gorilla gorilla | 25.0 | 2e-06 | 53.1 |
| LLPS-Cap-1339 | Cavia porcellus | 24.89 | 6e-07 | 55.1 |
| LLPS-Pat-2929 | Pan troglodytes | 24.64 | 3e-06 | 52.8 |
| LLPS-Pap-2045 | Pan paniscus | 24.64 | 3e-06 | 52.8 |
| LLPS-Caj-4732 | Callithrix jacchus | 23.15 | 8e-13 | 72.8 |