LLPS-Bot-4108
PKD2L1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Polycystin 2 like 1, transient receptor potential cation channel |
| Gene Name: | PKD2L1 |
| Ensembl Gene: | ENSBTAG00000010742.5 |
| Ensembl Protein: | ENSBTAP00000014222.4 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000014222.5 | ENSBTAP00000014222.4 |
| Ensembl | ENSBTAT00000071944.1 | ENSBTAP00000072780.1 |
| UniProt | F1N5R3, F1N5R3_BOVIN | |
| RefSeq | XM_015460714.1, XM_015469558.1 | XP_015316200.1, XP_015325044.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MNAVGSPEEQ ELQELGSGAW DNPTYSGPPS PRGTLKIYTI SSAVLSQPQP KQPEDGPQEK 60 61 AHRTLVSSCC LRICHGIRGL WGTTLTENTA ENRELYVKTT LRELLVYVVF LVDICLLTYG 120 121 MTSSSAYYYT KVMSELFLHT PSDTGISFQA ISSMEDFWDF AQGPLLDSLY WTKWYNNQSL 180 181 GHGSHSFIYY ENLLLGVPRL RQLRVRNDSC MVHEDFREDI LSCYDVYSPD EEEQLPFGPL 240 241 NGTAWTYHSQ DELGGSSHWG QLTSYSGGGY YLDLPGSRRA CEEALKDLKE GLWLDRGTRV 300 301 VFIDFSVYNA NINLFCVLRL VVEFPATGGA IPSWQIRTVK LIRYVSNWDF FIVGCEIAFC 360 361 IFIFYYIVEE ILELRIHRLR YLSSIWNILD LVVILLSIMA VGFHIFRTLE VNRLMGKLLQ 420 421 QPNMYADFEF LAFWQTQYNN MNAVNLFFAW IKIFKYISFN KTMTQLSSTL ARCAKDILGF 480 481 AVMFFLVFFA YAQLGYLLFG TQVENFSTFV KCIFTQFRII LGDFDYNAID NANRILGPVY 540 541 FVTYVFFVFF VLLNMFLAII NDTYSEVKEE LAGQKDELQL SDLLRQGYNK TLRRLHLRKE 600 601 QVSDVQKVLQ AGEQEIQFED FTNTLRELEH TEHETTKLTA AFTRFDQDGN GVLDEKEQKE 660 661 TQQKLEGERV AVHAEIENLG WSIVRSPPGE SSPKQAAKTG GWVSGEEFYT LTRRVLQLET 720 721 VLEGVMTQVD AMRSKLTMVE RKGWLAPLPG AGEQGIWEHL QAAPAVTPAP WGL 773 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAATGCTG TGGGAAGCCC CGAGGAGCAG GAGCTACAAG AGCTGGGGAG TGGAGCCTGG 60 61 GACAACCCCA CCTATAGCGG CCCCCCCTCC CCTCGAGGGA CCCTCAAGAT CTACACCATC 120 121 TCCAGTGCAG TGCTGTCTCA ACCCCAACCC AAGCAGCCTG AAGATGGACC CCAGGAGAAG 180 181 GCACACAGGA CCCTGGTGTC CAGCTGCTGC CTTCGCATCT GTCACGGCAT CAGAGGACTT 240 241 TGGGGAACGA CCTTGACTGA GAACACAGCT GAGAACCGGG AGCTGTATGT CAAGACCACC 300 301 CTGCGGGAGC TTTTGGTATA CGTCGTGTTC CTGGTGGACA TCTGTCTCTT GACCTATGGA 360 361 ATGACAAGCT CCAGTGCCTA TTACTACACC AAAGTGATGT CTGAGCTCTT CTTACATACC 420 421 CCATCGGACA CTGGAATCTC CTTCCAGGCC ATCAGCAGCA TGGAGGACTT CTGGGATTTT 480 481 GCCCAGGGCC CATTACTGGA CAGCTTGTAT TGGACCAAAT GGTACAACAA CCAGAGCCTG 540 541 GGCCACGGCT CCCACTCCTT CATCTACTAT GAGAACCTGT TGCTGGGGGT TCCGAGGCTG 600 601 CGGCAGCTGC GGGTCCGCAA TGACTCCTGC ATGGTGCATG AGGACTTCCG CGAGGACATT 660 661 CTGAGCTGCT ACGATGTCTA CTCCCCAGAC GAGGAAGAGC AACTCCCCTT TGGGCCCCTC 720 721 AATGGCACAG CATGGACCTA CCACTCGCAG GATGAGCTGG GGGGCTCCTC TCACTGGGGC 780 781 CAGCTCACAA GCTACAGTGG AGGTGGCTAC TACCTGGACC TTCCAGGATC TCGACGGGCC 840 841 TGTGAAGAGG CACTCAAGGA CCTTAAGGAG GGCCTATGGC TGGACAGGGG CACTCGGGTG 900 901 GTCTTCATCG ACTTCTCAGT CTACAATGCT AACATCAATC TTTTCTGTGT TCTGAGACTG 960 961 GTGGTGGAGT TTCCAGCTAC AGGAGGTGCC ATCCCATCCT GGCAAATCCG CACGGTTAAG 1020 1021 CTGATCCGCT ATGTCAGCAA CTGGGACTTC TTTATCGTTG GCTGTGAGAT TGCCTTCTGC 1080 1081 ATCTTCATCT TCTACTACAT AGTGGAGGAG ATCCTAGAGC TCCGCATCCA CAGGCTTCGT 1140 1141 TACCTCAGCA GCATCTGGAA CATTCTGGAC CTGGTGGTCA TCTTGCTCTC CATTATGGCT 1200 1201 GTGGGCTTCC ACATATTCCG AACCCTCGAG GTGAATCGGC TGATGGGGAA GCTTTTACAG 1260 1261 CAGCCAAACA TGTATGCTGA CTTTGAGTTC CTCGCCTTCT GGCAGACACA GTACAACAAC 1320 1321 ATGAACGCCG TCAACCTCTT CTTTGCCTGG ATCAAGATAT TCAAGTACAT CAGCTTCAAC 1380 1381 AAGACCATGA CCCAGCTCTC CTCCACGCTG GCCCGCTGTG CCAAGGACAT CTTGGGCTTT 1440 1441 GCCGTCATGT TCTTCCTTGT GTTTTTCGCC TATGCCCAGC TGGGCTACCT GCTTTTCGGG 1500 1501 ACCCAAGTGG AAAACTTCAG CACTTTCGTC AAGTGCATCT TCACTCAGTT CCGGATCATC 1560 1561 CTTGGGGACT TTGACTACAA TGCTATTGAC AACGCCAACC GCATCCTGGG ACCTGTTTAC 1620 1621 TTTGTCACCT ACGTCTTCTT CGTCTTCTTC GTGCTCCTGA ACATGTTCCT GGCCATCATC 1680 1681 AATGACACAT ATTCAGAGGT CAAGGAGGAG CTGGCTGGAC AAAAGGATGA GCTACAGCTT 1740 1741 TCAGACCTCC TGAGACAGGG CTACAACAAG ACCCTACGGA GGCTGCATCT GAGGAAGGAG 1800 1801 CAGGTTTCAG ATGTGCAGAA GGTCCTGCAG GCTGGGGAGC AGGAGATCCA GTTCGAGGAC 1860 1861 TTCACCAACA CCTTGAGGGA GCTGGAGCAC ACAGAGCATG AGACGACCAA GCTCACGGCT 1920 1921 GCCTTCACCA GGTTTGACCA AGATGGGAAC GGCGTCCTAG ACGAGAAGGA GCAGAAGGAG 1980 1981 ACGCAGCAGA AGCTGGAGGG GGAGAGGGTG GCTGTCCATG CTGAGATTGA GAACTTGGGC 2040 2041 TGGTCCATTG TGAGGAGCCC ACCAGGCGAG TCGAGTCCAA AGCAGGCTGC CAAAACAGGT 2100 2101 GGCTGGGTTT CGGGAGAAGA ATTCTACACG CTCACAAGGA GAGTTTTGCA GCTGGAGACT 2160 2161 GTCCTGGAAG GAGTCATGAC CCAGGTTGAT GCCATGAGGT CAAAGCTGAC GATGGTGGAG 2220 2221 AGGAAGGGGT GGCTGGCTCC TCTTCCAGGC GCAGGGGAAC AAGGCATTTG GGAGCACCTG 2280 2281 CAGGCAGCCC CAGCTGTGAC TCCAGCCCCC TGGGGACTCT AG 2322 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ova-3388 | Ovis aries | 96.25 | 0.0 | 1443 |
| LLPS-Urm-1835 | Ursus maritimus | 89.49 | 0.0 | 1329 |
| LLPS-Aim-3937 | Ailuropoda melanoleuca | 89.26 | 0.0 | 1328 |
| LLPS-Caf-4308 | Canis familiaris | 88.87 | 0.0 | 1333 |
| LLPS-Fec-1411 | Felis catus | 88.53 | 0.0 | 1285 |
| LLPS-Rhb-4687 | Rhinopithecus bieti | 88.1 | 0.0 | 1323 |
| LLPS-Paa-2291 | Papio anubis | 87.97 | 0.0 | 1320 |
| LLPS-Maf-0412 | Macaca fascicularis | 87.84 | 0.0 | 1321 |
| LLPS-Cea-4842 | Cercocebus atys | 87.84 | 0.0 | 1316 |
| LLPS-Mal-4308 | Mandrillus leucophaeus | 87.84 | 0.0 | 1317 |
| LLPS-Man-0737 | Macaca nemestrina | 87.84 | 0.0 | 1322 |
| LLPS-Mam-3488 | Macaca mulatta | 87.84 | 0.0 | 1322 |
| LLPS-Otg-0003 | Otolemur garnettii | 87.68 | 0.0 | 1259 |
| LLPS-Chs-3732 | Chlorocebus sabaeus | 87.58 | 0.0 | 1313 |
| LLPS-Hos-0125 | Homo sapiens | 87.58 | 0.0 | 1321 |
| LLPS-Pat-3704 | Pan troglodytes | 87.58 | 0.0 | 1322 |
| LLPS-Poa-4037 | Pongo abelii | 87.45 | 0.0 | 1309 |
| LLPS-Myl-1846 | Myotis lucifugus | 87.35 | 0.0 | 1313 |
| LLPS-Mup-1008 | Mustela putorius furo | 87.32 | 0.0 | 1296 |
| LLPS-Caj-0236 | Callithrix jacchus | 87.19 | 0.0 | 1314 |
| LLPS-Loa-1674 | Loxodonta africana | 87.12 | 0.0 | 1298 |
| LLPS-Aon-0233 | Aotus nancymaae | 87.06 | 0.0 | 1310 |
| LLPS-Gog-0172 | Gorilla gorilla | 86.93 | 0.0 | 1303 |
| LLPS-Ran-3128 | Rattus norvegicus | 85.83 | 0.0 | 1093 |
| LLPS-Pap-3672 | Pan paniscus | 85.77 | 0.0 | 1197 |
| LLPS-Ere-0869 | Erinaceus europaeus | 85.67 | 0.0 | 1082 |
| LLPS-Sus-3955 | Sus scrofa | 85.38 | 0.0 | 1270 |
| LLPS-Eqc-2913 | Equus caballus | 85.38 | 0.0 | 1292 |
| LLPS-Dio-2589 | Dipodomys ordii | 84.46 | 0.0 | 1252 |
| LLPS-Cap-4255 | Cavia porcellus | 83.75 | 0.0 | 1243 |
| LLPS-Mum-4848 | Mus musculus | 82.37 | 0.0 | 1229 |
| LLPS-Mea-2259 | Mesocricetus auratus | 81.39 | 0.0 | 1221 |
| LLPS-Fud-0243 | Fukomys damarensis | 79.74 | 0.0 | 1170 |
| LLPS-Orc-0400 | Oryctolagus cuniculus | 78.23 | 0.0 | 1248 |
| LLPS-Cas-2927 | Carlito syrichta | 75.55 | 0.0 | 1051 |
| LLPS-Mod-2965 | Monodelphis domestica | 75.0 | 0.0 | 1052 |
| LLPS-Sah-1467 | Sarcophilus harrisii | 73.83 | 0.0 | 1077 |
| LLPS-Tag-1655 | Taeniopygia guttata | 72.9 | 0.0 | 974 |
| LLPS-Anp-2668 | Anas platyrhynchos | 71.7 | 0.0 | 1048 |
| LLPS-Xet-3882 | Xenopus tropicalis | 70.43 | 0.0 | 945 |
| LLPS-Meg-1651 | Meleagris gallopavo | 70.33 | 0.0 | 1034 |
| LLPS-Fia-3307 | Ficedula albicollis | 70.15 | 0.0 | 1033 |
| LLPS-Gaga-2203 | Gallus gallus | 68.62 | 0.0 | 992 |
| LLPS-Anc-3193 | Anolis carolinensis | 68.61 | 0.0 | 915 |
| LLPS-Lac-3177 | Latimeria chalumnae | 66.62 | 0.0 | 982 |
| LLPS-Ten-2605 | Tetraodon nigroviridis | 65.56 | 0.0 | 885 |
| LLPS-Scm-1818 | Scophthalmus maximus | 65.19 | 0.0 | 880 |
| LLPS-Ora-0192 | Ornithorhynchus anatinus | 64.95 | 0.0 | 757 |
| LLPS-Leo-0017 | Lepisosteus oculatus | 64.63 | 0.0 | 924 |
| LLPS-Scf-0004 | Scleropages formosus | 64.38 | 0.0 | 834 |
| LLPS-Xim-3445 | Xiphophorus maculatus | 64.07 | 0.0 | 830 |
| LLPS-Tar-1507 | Takifugu rubripes | 63.24 | 0.0 | 811 |
| LLPS-Gaa-2306 | Gasterosteus aculeatus | 61.71 | 0.0 | 912 |
| LLPS-Asm-0161 | Astyanax mexicanus | 61.39 | 0.0 | 913 |
| LLPS-Pof-3709 | Poecilia formosa | 60.76 | 0.0 | 907 |
| LLPS-Dar-2835 | Danio rerio | 59.7 | 0.0 | 862 |
| LLPS-Orl-1583 | Oryzias latipes | 59.26 | 0.0 | 865 |
| LLPS-Orn-1793 | Oreochromis niloticus | 59.18 | 0.0 | 869 |
| LLPS-Pes-2343 | Pelodiscus sinensis | 59.16 | 0.0 | 549 |
| LLPS-Icp-0567 | Ictalurus punctatus | 58.23 | 0.0 | 829 |
| LLPS-Ict-3425 | Ictidomys tridecemlineatus | 51.43 | 4e-165 | 499 |
| LLPS-Nol-3252 | Nomascus leucogenys | 50.86 | 6e-167 | 503 |
| LLPS-Tut-0991 | Tursiops truncatus | 50.38 | 4e-165 | 499 |
| LLPS-Cae-1816 | Caenorhabditis elegans | 42.19 | 5e-106 | 347 |
| LLPS-Drm-1289 | Drosophila melanogaster | 40.69 | 2e-86 | 299 |
| LLPS-Chr-1610 | Chlamydomonas reinhardtii | 27.86 | 4e-15 | 84.3 |